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CoolVox:Advanced 3D convolutional neural network models for predicting solar radiation on building facades

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Building Simulation 2022年第5期15卷 755-768页

作者： jung Min Han eun Seuk Choi Ali Malkawi Harvard University Graduate School of Design CambridgeUSA Harvard Center for Green Buildings and Cities CambridgeUSA Harvard John A.Paulson School of Engineering and Applied Sciences CambridgeUSA

Data-driven models have become increasingly prominent in the building,architecture,and construction *** area ideally suited to exploit this powerful new technology is building performance ***-based models have traditionally been used to estimate the energy flow,air movement,and heat balance of ***,physics-based models require many assumptions,significant computational power,and a considerable amount of time to output *** neural networks(ANNs)with prefabricated or simulated data are likely to be a more feasible option for environmental analysis conducted by designers during the early design *** ANNs require fewer inputs and shorter computation times and offer superior performance and potential for data augmentation,they have received increased attention for predicting the surface solar radiation on ***,ANNs can provide innovative and quick design solutions,enabling designers to receive instantaneous feedback on the effects of a proposed change to a building's *** research introduces deep learning methods as a means of simulating the annual radiation intensities and exposure level of buildings without the need for physics-based *** propose the CoolVox model to demonstrate the feasibility of using 3D convolutional neural networks to predict the surface radiation on building *** CoolVox model accurately predicted the radiation intensities of building facades under different boundary conditions and performed better than ARINet(with average mean square errors of 0.01 and 0.036,respectively)in predicting the radiation intensity both with(validation error=0.0165)and without(validation error=0.0066)the presence of boundary buildings.

关键词： artificial neural networks 3D convolutional neural networks solar radiation simulation building performance simulation

Applications of scaffolds:Tools for enhancing the immunomodulation of mesenchymal stromal cells

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BIOCELL 2022年第6期46卷 1439-1443页

作者： OK-HYEON KIM eun RAN KIM jun HYUNG PARK HYUN jung LEE Department of Anatomy and Cell Biology College of MedicineChung-Ang UniversitySeoul06974South Korea Department of Global Innovative Drugs Graduate School of Chung-Ang UniversitySeoul06974South Korea Severance Biomedical Science Institute Yonsei Biomedical Research InstituteCollege of MedicineYonsei UniversitySeoul03722South Korea

Exogenously delivered mesenchymal stromal cells(MSCs)are therapeutically beneficial owing to their paracrine effect;they secrete various cytokines,nucleic acids,and *** bioengineering techniques can help MSC cultures to release secretomes by providing stem cell niche-like conditions(both structurally and functionally).Various scaffolds mimic the natural extracellular matrix(ECM)using both natural and synthetic polymers,providing favorable environments for MSC proliferation and *** on material properties,either topographically or elastically structured scaffolds can be ***-dimensional scaffolds have tunable substrate rigidities and structures,aiding MSC *** ECM-derived hydrogels are similar to the natural ECM,thus improving the paracrine effects of ***,we discuss recent research on the application of scaffolds to maximize the immunomodulatory function of MSCs.

关键词： Extracellular matrix(ECM) Immunomodulation Mesenchymal stromal cells(MSCs) Scaffolds Stem cell niche

Translocator protein 18 kDa(TSPO): old dogma, new mice, new structure, and new questions for neuroprotection

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Neural Regeneration Research 2015年第6期10卷 878-880页

作者： eun-jung Kim Seong-Woon Yu Department of Brain and Cognitive Science Daegu Gyeongbuk Institute of Science and Technology (DGIST)

The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,

关键词： TSPO old dogma Translocator protein 18 kDa new mice new structure

Thermal energy harvesting circuit with maximum power point tracking control for self-powered sensor node applications

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Frontiers of Information Technology & Electronic Engineering 2018年第2期19卷 285-296页

作者： eun-jung YOON Jong-Tae PARK Chong-Gun YU Department of Electronics Engineering Incheon National University

We present a simple implementation of a thermal energy harvesting circuit with the maximum power point tracking（MPPT） control for self-powered miniature-sized sensor nodes. Complex start-up circuitry and direct current to direct current（DC-DC） boost converters are not required, because the output voltage of targeted thermoelectric generator（TEG） devices is high enough to drive the load applications directly. The circuit operates in the active/asleep mode to overcome the power mismatch between TEG devices and load applications. The proposed circuit was implemented using a 0.35-μm complementary metal-oxide semiconductor（CMOS） process. Experimental results confirmed correct circuit operation and demonstrated the performance of the MPPT scheme. The circuit achieved a peak power efficiency of 95.5% and an MPPT accuracy of higher than 99%.

关键词： Thermoelectric energy Energy harvesting Maximum power point tracking (MPPT) control Self-powered system Sensor node

Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy

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World Journal of Gastrointestinal Oncology 2021年第8期13卷 915-928页

作者： Kabsoo Shin eun-Kyo jung Se jun Park Sangwoon Jeong In-Ho Kim Myung-ah Lee Division of Medical Oncology Department of Internal MedicineSeoul St.Mary's HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Catholic Cancer Research Institute College of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND A decline in serum carbohydrate antigen 19-9(CA19-9)levels during systemic chemotherapy is considered as a prognostic marker for patients with advanced pancreatic ***-to-lymphocyte ratio(NLR)has been extensively studied as a simple and useful indicator of prognosis in various cancers including pancreatic *** To assess the prognostic significance of NLR and CA19-9 in patients with advanced pancreatic adenocarcinoma received first-line chemotherapy according to CA19-9 *** We retrospectively analyzed patients diagnosed with advanced pancreatic cancer who received first-line chemotherapy between January 2010 and July 2017 at the Catholic University of Seoul ***’s *** were divided according to CA19-9 positivity(CA19-9-positive vs-negative groups)and pre-and posttreatment NLR *** determine cut-off value of NLR and CA19-9 reduction,time-dependent receiver operating characteristic curve was *** evaluated overall survival(OS)and progression-free survival(PFS)for each group using Kaplan-Meier method,and we performed multivariate analyses on the entire *** We included 271 patients in this ***-off value of NLR and CA19-9 reduction was determined as 2.62 and 18%.Multivariate analysis showed that post-treatment NLR<2.62 and reduction of≥18%of baseline CA19-9 were significantly associated with OS and ***-treatment NLR≥2.62 showed hazard ratio(HR)of 2.47[95%confidence interval(CI):1.84-3.32,P<0.001]and CA19-9 decline(≥18%)showed HR of 0.51(95%CI:0.39-0.67,P<0.001)for *** CA19-9-positive patients were divided into groups according to CA19-9 response(responder vs non-responder)and post-treatment NLR(<2.62 vs≥2.62),CA19-9 responder and post-treatment NLR<2.62 group showed better survival than CA19-9 non-responder and post-treatment NLR≥2.62 group(OS 11.0 mo vs 3.9 mo,P<0.001;PFS 6.3 mo vs 2.0 mo,P<0.001).The combination of CA19-9 decline and post-treatment NLR showed a significant c

关键词： Pancreatic adenocarcinoma Serum carbohydrate antigen 19-9 Neutrophil-tolymphocyte ratio Multivariate analysis Prognosis Chemotherapy

3-D geochemical interpolation guided by geophysical inversion models

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Geoscience Frontiers 2021年第3期12卷 132-145页

作者： Tom Horrocks eun-jung Holden Daniel Wedge ChrisWijns Centre for Exploration Targeting.School of Earth Sciences University of Western AustraliaCrawleyWA 6009Australia

3-D geochemical subsurface models,as constructed by spatial interpolation of drill-core assays,are valuable assets across multiple stages of the mineral industry's ***,the accuracy of such models is limited by the spatial sparsity of the underlying drill-core,which samples only a small fraction of the *** limitation can be alleviated by integrating collocated 3-D models into the interpolation process,such as the 3-D rock property models produced by modern geophysical inversion procedures,provided that they are sufficiently resolved and correlated with the interpolation *** standard machine learning algorithms are capable of predicting the target property given these data,incorporating spatial autocorrelation and anisotropy in these models is often not *** propose a Gaussian process regression model for 3-D geochemical interpolation,where custom kernels are introduced to integrate collocated 3-D rock property models while addressing the trade-off between the spatial proximity of drill-cores and the similarities in their collocated rock properties,as well as the relative degree to which each supporting 3-D model contributes to *** proposed model was evaluated for 3-D modelling of Mg content in the Kevitsa Ni-Cu-PGE deposit based on drill-core analyses and four 3-D geophysical inversion *** the inversion models improved the regression model's likelihood(relative to a purely spatial Gaussian process regression model)when evaluated at held-out test holes,but only for moderate spatial scales(100 m).

关键词： Machine learning Gaussian process regression Kriging Geophysical inversion Interpolation

Hybrid algorithm for modeling of fluid-structure interaction in incompressible, viscous flows

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Acta Mechanica Sinica 2012年第4期28卷 1030-1041页

作者： eun jung Chae Deniz Tolga Akcabay Department of Naval Architecture and Marine Engineering University of Michigan

The objective of this paper is to present and to validate a new hybrid coupling （HC） algorithm for modeling of fluid-structure interaction （FSI） in incompressible, viscous flows. The HC algorithm is able to avoid numerical instability issues associated with artificial added mass effects, which are often encountered by standard loosely coupled （LC） and tightly coupled （TC） algorithms, when modeling the FSI response of flexible structures in incompressible flow. The artificial added mass effect is caused by the lag in exchange of interfacial displacements and forces between the fluid and solid solvers in partitioned algorithms. The artificial added mass effect is much more prominent for light/flexible struc- tures moving in water, because the fluid forces are in the same order of magnitude as the solid forces, and because the speed at which numerical errors propagate in an incom- pressible fluid. The new HC algorithm avoids numerical instability issues associated with artificial added mass effects by embedding Theodorsen＇s analytical approximation of the hydroelastic forces in the solution process to obtain better initial estimates of the displacements. Details of the new HC algorithm are presented. Numerical validation studies are shown for the forced pitching response of a steel and a plastic hydrofoil. The results show that the HC algorithm is able to converge faster, and is able to avoid numerical insta- bility issues, compared to standard LC and TC algorithms, when modeling the transient FSI response of a plastic hydrofoil. Although the HC algorithm is only demonstrated for a NACA0009 hydrofoil subject to pure pitching motion, the method can be easily extended to model general 3-D FSI response and stability of complex, flexible structures in turbulent, incompressible, multiphase flows.

关键词： Fluid-structure interaction Viscous Incom- pressible Computational Added Mass Stability

InIncidence and clinical features of endoscopic ulcers developing after gastrectomy

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World Journal of Gastroenterology 2012年第25期18卷 3260-3266页

作者： Woo Chul Chung eun jung Jeon Kang-Moon Lee Chang Nyol Paik Sung Hoon jung jung Hwan Oh Ji Hyun Kim Kyong-Hwa jun Hyung Min Chin Department of Internal Medicine The Catholic University of KoreaSeoul 130-709South Korea Department of Surgery The Catholic University of Korea College of MedicineSeoul 130-709South Korea

AIM： To determine the precise incidence and clinica features of endoscopic ulcers following gastrectomy. METHODS： A consecutive series of patients who un- derwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ulcers following gastrectomy were enrolled. We analyzed differences in patient age, sex, size of the le- sions, method of operation, indications for gastric resec- tion, and infection rates of Helicobacterpylor/（H. pylor/~ between the nonulcer and ulcer groups. RESULTS： The incidence of endoscopic ulcers after gastrectomy was 9.3% and that of marginal ulcers was 8.6%. Ulcers were more common in patients with Billroth l] anastomosis and pre-existing conditions forpeptic ulcer disease （PUD）. Infection rates of H. pylori- did not differ significantly between the two groups. The patients who underwent operations to treat PUD had lower initial levels of hemoglobin and higher rates of hospital admission. CONCLUSION： H. pylori was not an important factor in ulcerogenesis following gastrectomy. For patients who underwent surgery for PUD, clinical course of mar- ginal ulcers was more severe.

关键词： Gastrectomy Marginal ulcer Helicobacterpylori

Effects of Polymeric Stabilizers on the Synthesis of Gold Nanoparticles

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Journal of Materials Science & Technology 2014年第2期30卷 107-111页

作者： eun jung Kim Jeong Hyun Yeum Jin Hyun Choi Department of Advanced Organic Materials Science and Engineering Kyungpook National University Department of Bio-fibers and materials Science Kyungpook National University

Gold nanoparticles （AuNPs） stabilized with sodium alginate （SA）, glycol chitosan （GC）, polyvinyl alcohol （PVA）, and polyethyleneimine （PEI） were synthesized in aqueous solutions at room temperature. Different sizes and size distributions of AuNPs were obtained according to the polymeric stabilizers. The mean particle diameters of AuNPs synthesized with GC and PVA as stabilizers were about 5.1 and 5.3 nm, respectively, while those of AuNPs stabilized with SA and PEI were 8.4 and 10.8 nm, respectively. When SA was used, relatively large particles aggregated to form large clusters. In the case of GC, a number of small particles built up large clusters. When PVA was used, the size and the number of nanoperticles were estimated small with a low weight content of Au. For this reason, the PVA-stabilized AuNPs formed clusters with a small hydrodynamic size. The AuNPs synthesized in the aqueous solution of PEI without a reducing agent, sodium borohydride, were uniform in size and formed the smallest nanoclusters （67.4 nm）. In this case, the highest Au content was obtained. Sufficiently grown nanoparticles with a high Au content and a limited hydrodynamic size are considered to be suitable for a variety of applications.

关键词： Gold nanoparticles Sodium alginate Glycol chitosan Polyvinyl alcohol Polyethyleneimine