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Analysis of Herbal Medicine Prescriptions for Patients in An Academic Korean Medical Hospital:A Cross Sectional Study of Electronic Medical Records(2010–2013)

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Chinese Journal of Integrative Medicine 2018年第6期24卷 467-473页

作者： Byung-Wook Lee Hyeon-Yeop Lee Kwang-Ho Heo Hyun-Woo Cho Man-Suk hwang In Heo Byung-Cheul Shin eui-hyoung hwang Department of Classics and Medical History College of Korean MedicineDongguk University Dongje Medical Co. Ltd. Department of Korean Medicine Yeongam Public Health Center Department of Third Green Oriental HospitalBu-cheon (14582)Republic of Korea Department of Korean Medical Science School of Korean MedicinePusan National University Department of Rehabilitation Medicine of Korean Medicine Dae-Jeon Korean Medicine HospitalDae-Jeon University Department of Rehabilitation Medicine of Korean Medicine Korean Medicine HospitalPusan National University

Objective： To obtain fundamental information for the standardization of herbal medicine in Korea. Methods： We analyzed the herbal medicine prescription data of patients at the Pusan National University Korean Medicine Hospital from March 2010 to February 2013. We used the Dongui-Bogam （Dong Yi Bao Jian） to classify prescribed herbal medicines. Results： The study revealed that the most frequently prescribed herbal medicine was ‘Liuwei Dihuang Pill （LWDHP, 六味地黄丸）＇ which was used for invigorating ‘Shen （Kidndy）-yin＇. ‘LWDHP＇ was most frequently prescribed to male patients aged 50-59, 60-69, 70-79 and 80-89 years, and ‘Xionggui Tiaoxue Decoction （XGTXD, 芎归调血饮）＇ was most frequently prescribed to female patients aged 30-39 and 40-49 years. According to the International Classification of Diseases （ICD） codes,‘Diseases of the musculoskeletal system and connective tissue＇ showed the highest prevalence. ‘LWDHP＇ and ＇XGTXD＇ was the most frequently prescribed in categories 5 and 3, respectively. Based on the percentage of prescriptions for each sex, ‘Ziyin Jianghuo Decoction （滋阴降火汤）＇ was prescribed to mainly male patients, and ‘XGTXD＇ with ‘Guima Geban Decoction （桂麻各半汤）＇ were prescribed to mainly female patients. Conclusion： This study analysis successfully determined the frequency of a variety of herbal medicines, and many restorative herbal medicines were identified and frequently administered.

关键词： herbal medicine herbal medicine prescription traditional Korean medicine Chinese medicine electronic medical record Dongui-Bogam

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Fatty acid methyl ester profiles and nutritive values of 20 marine microalgae in Korea

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Asian Pacific Journal of Tropical Medicine 2015年第3期8卷 191-196页

作者： Sung-Suk Suh So Jung Kim Jinik hwang Mirye Park Taek-Kyun Lee eui-Joon Kil Sukchan Lee South Sea Environment Research Department Korea Institute of Ocean Science and Technology Kyeongbuk Institute for Marine Bio-Industry Department of Genetic Engineering Sungkyunkwan University

Objecive:To screen the fatty acid(FA) composition of 20 marine microalgae species,including seven Diophyceae,six Bacillariophyeae four Chlorophyceae,two Haptophyceae and one Raphidophyceae ***:Microalgal cells cultured at the Korea Institute of Ocean Science & Technology were harvested during the late exponential growth phase and the FA composition ***:The FA composition of microalgae was *** example,seven different species of Dinophyceae were composed primarily of C14:0,C16:0.C18:0.C20:4n-6.C20:5n-3 and C22:*** C14:0.C16:0,C16:1.C18:0.C20:5n-3 and C22:6n-3 were abundant FAs in six species of *** addition,four Chlurophyceae,two Haptopkyeeae and one Raphidophyceae species all contained a high degree of C16:1 n-7[(9.2R-34.91)%and(34.48-35.04)%].C14:0[(13.34-25.96)%]and[(26.69-Z8.24)%],and C16:0[(5.89-29.15)%]and[(5.70-16.81)%].Several factors contribute to the nutritional value of *** the polyunsaturated FA content and n-3 to n-6 FA ratio,which could be used to assess the nutritional quality of ***:This study is the first comprehensive assessment of the FA composition and nutritional value of microalgae species in South Korea,and identifies the potential utility of FAs as species-specific biomarkers.

关键词： Microalgae PUFA Nutritive values DHA EPA

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Fabrication of two-layer flexible copper clad laminate by electroless-Cu plating on surface modified polyimide

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中国有色金属学会会刊：英文版 2009年第4期19卷 970-974页

作者： Soo-Min hwang Jun-Hyung LIM Chang-Min LEE eui-Cheol PARK Jun-Hyuk CHOI Jinho JOO Hoo-Jeong LEE Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

A flexible copper clad laminate(FCCL) was fabricated using electroless-and electro-Cu plating processes and the effects of pre-treatment time on the adhesion strength of the FCCL were evaluated based on interfacial *** neutralization and catalyst time were varied in the range of 0-20 min and 0.1-10 min,respectively,and the interfacial condition of the FCCL was characterized by atomic force microscopy(AFM) and X-ray photoelectron spectroscopy(XPS).It is observed that the peel strength increases significantly as the neutralization and catalyst time *** strength as high as 7.2-7.3 N/cm is obtained as the neutralization and catalyst time increase up to 20 min and 10 min,respectively,which is comparable to the strength achieved by the conventional laminating and sputtering *** improvements are probably due to an increase in the surface roughness of polyimide(PI),the activated surface condition,and the adsorption of palladium ions/atoms(Pd) on the PI surface which act as nucleation sites for Cu.

关键词：聚酰亚胺表面改性化学制备层压板铜电镀铜箔软性 X射线光电子能谱

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Characterization of flexible copper laminates fabricated by Cu electro-plating process

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中国有色金属学会会刊：英文版 2009年第4期19卷 965-969页

作者： Chang-Min LEE Jun-Hyung LIM Soo-Min hwang eui-Cheol PARK Jong-Hyun SHIM Jin-Hyun PARK Jinho JOO Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

Flexible copper clad laminates(FCCLs) were fabricated using the electro-plating process and the combined effect of the current density and plating time on their surface morphology,texture,hardness,electrical resistivity and folding behavior was *** achieve Cu layers with similar thicknesses,the current density was varied in the range of 0.2-3 A/dm2 and the plating time was controlled in the range of 0.5-7.5 h to compensate for the variation of the current *** surface morphology,hardness,and folding behavior were characterized by atomic force microscopy,nanoindentation technique and Massachusett Institute of Technology folding endurance test,*** X-ray diffraction patterns indicated that the Cu phase was formed without any secondary phases;however,the preferred orientation changed from(220) to(111) as the current density increased over 1 A/*** addition,it was observed that the root-mean-square and hardness values decreased when the current density increased and the plating time decreased *** electrical resistivity was as low as approximately 21 nΩ·m and the number of cycles without failure in the folding test was over 15 000,which were comparable to those of commercial FCCLs.

关键词：电镀工艺层压板铜层制备表征电流密度原子力显微镜纳米压痕技术

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Roles of humidity and heat treatment temperatures on YBa_2Cu_3O_(7-x) coated conductors by trifluoroacetic acid-metal organic deposition process

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中国有色金属学会会刊：英文版 2009年第4期19卷 956-960页

作者： Seok-Hern JANG Jun-Hyung LIM Chang-Min LEE eui-Cheol PARK Soo-Min hwang Jun-Hyuk CHOI Jong-Hyun SHIM Jin-Hyun PARK Won KIM Jinho JOO School of Advanced Materials Science and Engineering Sungkyunkwan University

YBa2Cu3O7-x(YBCO) films were fabricated on an LAO substrate using the trifluoroacetic acid-metal organic deposition(TFA-MOD) method and the effects of the humidity and heat treatment temperatures on the microstructure,degree of texture and critical properties of the films were *** order to understand the combined effects of the humidity and the calcining and firing temperatures on critical properties,heat-treatment was performed at various temperatures with the other processing variables *** films were calcined at 400-430 ℃ and fired at 750-800 ℃ in a 0-12.1% humidified Ar-O2 *** texture was determined by pole-figure *** amount of the BaF2 phase was effectively reduced and a sharp and strong biaxial texture was formed under a humidified atmosphere,which led to increased critical *** addition,the microstructure varied significantly with firing temperature but changed little with calcining *** highest IC of 40 A/cm-width,which corresponds to JC value of 1.8 MA/cm2,was obtained for the films fired at 775 ℃(in 12.1% humidity) after calcining at 400-430 ℃.It is likely that the highest IC value is due to the formation of a more pure YBCO phase,c-axis grains,and a denser microstructure.

关键词： YBa2Cu3O7 热处理温度三氟乙酸沉积过程湿度涂层导体有机金属微观结构变化

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Harnessing novel engineered feeder cells expressing activating molecules for optimal expansion of NK cells with potent antitumor activity

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Cellular & Molecular Immunology 2022年第2期19卷 296-298页

作者： Bokyung Min Bitna Yang You-Sun Kim Gyeong Min Park HyunAh Kim Hyojin Kim Eun-Ji Kim Yu Kyeong hwang eui-Cheol Shin Sungyoo Cho BioMedical Science and Engineering Interdisciplinary Program KAISTDaejeonKorea Cell Therapy Research Center GC LabCellYonginKorea Laboratory of Immunology and Infectious Diseases Graduate School of Medical Science and EngineeringKAISTDaejeonKorea

Natural killer(NK)cells play an important role in the antitumor immune response as the major cytotoxic lymphocytes in the innate immune *** cells without any genetic modifications have been used for both autologous and allogeneic ***,many reports have suggested that allogeneic NK cells can reduce the recurrence of disease and improve survival through a graft-versus-leukemia effect without GVHD[1,2].

关键词： killer expressing optimal

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Lithium plating-free 1 Ah-level high-voltage lithium-ion pouch battery via ambi-functional pentaerythritol disulfate

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能源化学:英文版 2023年第8期83卷 229-238,I0007页

作者： Dung Tien Tuan Vu Jinsol Im Jae-Hee Kim Jisoo Han Gyeong Jun Chung Giang Thi Huong Nguyen Junhyeok Seo Minjae Kim eui-Hyung hwang Young-Gil Kwon Jae Wook Shin Kuk Young Cho Seung-Wan Song Department of Chemical Engineering&Applied Chemistry Chungnam National UniversityDaejeon 34134Republic of Korea Department of Materials Science&Chemical Engineering Hanyang UniversityAnsan 15588Republic of Korea Fine Chem Co.Ltd. Daejeon 34365Republic of Korea d CSIM Co.Ltd. Yesan 32400Republic of Korea Dongwha Electrolyte Nonsan 32925Republic of Korea

Elevating the charge cut-off voltage beyond traditional 4.2 V is a commonly accepted technology to increase the energy density of Li-ion batteries(LIBs) but the risk of Li-dendrites and fire hazard increases as well. The use of ambi-functional additive, which forms stable solid electrolyte interphase(SEI) simultaneously at both cathode and anode, is a key to enabling a dendrites-free and well-working high-voltage LIB. Herein, a novel ambi-functional additive, pentaerythritol disulfate(PEDS), at 1 wt% without any other additive is demonstrated. We show the feasibility and high impacts of PEDS in forming lithium sulfateincorporated robust SEI layers at NCM523 cathode and graphite anode in 1 Ah-level pouch cell under4.4 V, 25 °C and 0.1 C rate, which mitigates the high-voltage instability, metal-dissolution and cracks on NCM523 particles, and prevents Li-dendrites at graphite anode. Improved capacity retention of 83%after 300 cycles is thereby achieved, with respect to 69% with base electrolyte, offering a promising path toward the design of practical high-energy LIBs.

关键词： Lithium-ion pouch cell Lithium plating-free High-voltage Ambi-functional additive SEI layer

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Computation of Impact Factor of High-Speed Railway Bridge by KTX Train Riding Test

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Engineering（科研） 2013年第9期5卷 751-755页

作者： Hyejin Yoon Won Jong Chin Jae Yoon Kang Jongwon Kwark eui-Seung hwang Department of Civil Engineering Kyung Hee University Goyang South Korea Structural Engineering Research Division Korea Institute of Construction Technology Goyang South Korea

The design live load of railway is divided into common railway and high-speed railway separately inKorea. Accordingly, the Korean design specification of railway specifies the impact factor for common railway and high-speed railway respectively. The impact factor for high-speed railway is based on Eurocode. Since the impact factor criteria inKoreawere established by adopting those of the Eurocode and without dedicated investigation relying on research results reflecting the domestic circumstances, thorough examination should be implemented on these criteria. Therefore the evaluation of impact factor based on field tests is required. Both dynamic and static vertical displacements are necessary to compute the impact factor. The dynamic response can be obtained from the measurement of deflection of the bridge slab crossed by the firstKoreahigh-speed train (KTX, Korea Train eXpress) running at high-speed. The main difficulties encountered are in obtaining static response because static response corresponds to the response of the bridge when the train remains immobile on the bridge or crosses the bridge at speed slower than5 km/hr. This study introduces the static response derived by applying the moving average method on the dynamic response signal. To that goal, field measurements was conducted under train speeds of5 km/hr and ranging from100 km/hr to300 km/hr on Yeonjae Bridge located in the trial section of the Gyeonbu High-Speed Railway Line before its opening. The validity of the application of the moving average method is verified from comparison of measured static response and derived static response by moving average method. Moreover, evaluation is conducted on the impact factor computed for a bridge crossed by the KTX train running at operational speed.

关键词： High-Speed Railway Dynamic Response Impact Factor Moving Average Method

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Comparison Study and Forensic Analysis between Experiment and Coupled Dynamics Simulation for Submerged Floating Tunnel Segment with Free Ends under Wave Excitations

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Computer Modeling in Engineering & Sciences 2023年第10期137卷 155-174页

作者： Woo Chul Chung Chungkuk Jin Moo Hyun Kim Ju-young hwang Division of Mechanical Engineering Korea Maritime&Ocean UniversityBusanSouth Korea Department of Ocean Engineering and Marine Sciences Florida Institute of TechnologyMelbourneFLUSA Department of Ocean Engineering Texas A&M UniversityCollege StationTXUSA Department of Civil Engineering Dong-Eui UniversityBusanSouth Korea

This paper presents dynamic-behavior comparisons and related forensic analyses of a submerged floating tunnel(SFT)between numerical simulation and physical experiment under regular and irregular *** experiments are conducted in the 3Dwave tank with 1:33.3 scale,and the corresponding coupled time-domain simulation tool is devised for *** entire SFT systemconsists of a long concrete tunnel and 12 tubular aluminummooring *** numerical simulation models,the Cummins equation with 3D potential theory including second-order wave-body interaction effects and the much simpler Morison-equation-based formula with the lumped-massbased line model,are designed and *** analyses for mooring-line adjustments in the simulation are carried out in view of the best representation of the physical *** that,the measured pre-tension distribution and systemstiffness of twelvemooring lines arewell reproduced in the ***,the dynamic responses and mooring tensions of the SFT are compared under regular and irregular *** measured and simulated results coincide reasonably well for both regular-and irregular-wave conditions.

关键词： Submerged floating tunnel comparative study forensic analysis mooring-line modeling dynamic response mooring tension

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Effect of molybdenum on interfacial properties of titanium carbide reinforced Fe composite

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Journal of Materials Science & Technology 2022年第12期107卷 252-258页

作者： Seungchan Cho Junghwan Kim Ilguk Jo Jae Hyun Park Jaekwang Lee Hyun-Uk Hong Bong Ho Lee Wook Ryol hwang Dong-Woo Suh Sang-Kwan Lee Sang-Bok Lee Composites Research Division Korea Institute of Materials Science(KIMS)Changwon 51508South Korea Advanced Materials Engineering Dong-Eui UniversityBusan 47340South Korea Department of Aerospace and Software Engineering Gyeongsang National UniversityJinju 52828South Korea Department of Physics Pusan National UniversityBusan 46241South Korea Department of Materials Convergence and System Engineering Changwon National UniversityChangwon 51140South Korea Center for Core Research Facilities Daegu Gyeongbuk Institute of Science and TechnologyDaegu 42988South Korea School of Mechanical Engineering Gyeongsang National UniversityJinju 52828South Korea Graduate Institute of Ferrous Technology Pohang University of Science and TechnologyGyeongbuk 37673South Korea

This study shows that the mechanical strength of the composite of Fe matrix and titanium carbide(Ti C)ceramic particles is significantly enhanced with addition of molybdenum(Mo) atoms. Ti C reinforced Fe(Fe-0.2C-7Mn) composites with and without Mo were fabricated by a liquid pressing infiltration(LPI)process and the effect of Mo on interfacial properties of TiC–Fe composite was investigated using atomic probe tomography(APT) analysis, molecular dynamics(MD) simulations, first-principle density functional theory(DFT), and thermodynamic calculations. First, DFT calculations showed that total energies of the Mo-doped Ti C–Fe superlattices strongly depend on the position of Mo defects, and are minimized when the Mo atom is located at the TiC/Fe interface, supporting the probable formation of MoC-like interphase at the TiC/Fe interface region. Then, APT analysis confirmed the DFT predictions by finding that about6.5 wt.% Mo is incorporated in the Ti C–Fe(Mo) composite and that sub-micrometer thick(Ti,Mo)C interphase is indeed formed near the interface. The MD simulations show that Mo atoms migrate to the Mo-free TiC–Fe interface at elevated temperatures and the mechanical strength of the interface is considerably enhanced, which is in good agreement with experimental observations.

关键词： Metal matrix composites(MMCs) Titanium carbide Fe matrix composite Infiltration Molybdenum Interfacial property

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