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Prognostic role of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with non-metastatic and metastatic prostate cancer:A meta-analysis and systematic review

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Asian Journal of Urology 2024年第2期11卷 191-207页

作者： Stefano Salciccia marco Frisenda Giulio Bevilacqua Pietro Viscuso Paolo Casale ettore De Berardinis Giovanni Battista Di Pierro Susanna Cattarino Gloria Giorgino Davide Rosati Francesco Del Giudice Alessandro Sciarra Gianna mariotti Alessandro Gentilucci Department of Urology Sapienza Rome UniversityPoliclinico Umberto I00161 RomeItaly Department of Urology Humanitas20089 RozzanoMIItaly

Objective: To analyze data available in the literature regarding a possible prognostic value of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in prostate cancer (PCa) patients stratified in non-metastatic and metastatic ***: A literature search process was performed following the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. In our meta-analysis, the pooled event rate estimated and the pooled hazard ratio were calculated using a random effect ***: Forty-two articles were selected for our analysis. The pooled risk difference for non-organ confined PCa between high and low NLR cases was 0.06 (95% confidence interval [CI]: −0.03-0.15) and between high and low PLR cases increased to 0.30 (95% CI: 0.16-0.43). In non-metastatic PCa cases, the pooled hazard ratio for overall mortality between high and low NLR was 1.33 (95% CI: 0.78-1.88) and between high and low PLR was 1.47 (95% CI: 0.91-2.03), whereas in metastatic PCa cases, between high and low NLR was 1.79 (95% CI: 1.44-2.13) and between high and low PLR was 1.05 (95% CI: 0.87-1.24).Conclusion: The prognostic values of NLR and PLR in terms of PCa characteristics and responses after treatment show a high level of heterogeneity of results among studies. These two ratios can represent the inflammatory and immunity status of the patient related to several conditions. A higher predictive value is related to a high NLR in terms of risk for overall mortality in metastatic PCa cases under systemic treatments.

关键词： Prostatic neoplasm Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyteratio Meta-analysis Radical prostatectomy Metastatic

Minimally invasive surgical therapies(MISTs)for lower urinary tract symptoms(LUTS):promise or panacea?

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Asian Journal of Andrology 2024年第2期26卷 135-143页

作者： Gian maria Busetto Andrea Checchia marco Recchia Edoardo Tocci Ugo G Falagario Gennaro Annunziata Pasquale Annese Nicola d'Altilia Vito mancini matteo Ferro Felice Crocetto Octavian Sabin Tataru Luca Di Gianfrancesco Angelo Porreca Francesco Del Giudice ettore De Berardinis Carlo Bettocchi Luigi Cormio Giuseppe Carrieri University of Foggia Foggia 71122Italy Department of Urology and Renal Transplantation Policlinico of FoggiaFoggia 71122Italy Urology Unit "G.Tatarlla"HospitalCerignola 71042Italy Urology Unit European Institute of Oncology(IE0)IRCcSMilan 20141Italy University of Naples Federico Il Naples 80126Italy G.E.Palade University of Medicine PharmacyScienceand Technology of Targu MuresTargu Mures 540142Romania Department of Oncological Urology Veneto Institute of Oncology(IOv)IRccSPadua 35128Italy Department of maternal-Infant and Urological Sciences Sapienza Rome UniversityRoma 00161Italy Urology Unit "L.Bonomo"HospitalAndria 76123Italy

The increasing importance of treatment of lower urinary tract symptoms(LUTS),while avoiding side effects and maintaining sexual function,has allowed for the development of minimally invasive surgical therapies(MiSTs).Recently,the European Association of Urology guidelines reported a paradigm shift from the management of benign prostatic hyperplasia(BPH)to the management of nonneurogenic male *** aim of the present review was to evaluate the efficacy and safety of the most commonly used MisTs:ablative techniques such as aquablation,prostatic artery embolization,water vapor energy,and transperineal prostate laser ablation,and nonablative techniques such as prostatic urethral lift and temporarily implanted nitinol device(iTIND).MiSTs are becoming a new promise,even if clinical trials with longer follow-up are still *** of them are still under investigation and,to date,only a few options have been given as a recommendation for *** cannot be considered as standard of care and are not suitable for all *** and disadvantages should be underlined,without forgetting our objective:treatment of LUTS and re-treatment avoidance.

关键词： aquablation iTIND prostatic artery embolization prostatic urethral lift transperineal prostate laser ablation water vapor energy

Impacts of COVID-19 Pandemic on Italian Electricity Demand and markets

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CSEE Journal of Power and Energy Systems 2023年第2期9卷 824-827页

作者： mahmood Hosseini Imani ettore Bompard Pietro Colella Tao Huang Politecnico di Torino Dipartimento EnergiaTurin10129Italy

In this paper,the short-,medium-,and long-term effects of the COVID-19 pandemic on the Italian power system,particularly electricity consumption behavior and electricity market prices,are investigated by defining various *** investigation reveals that COVID-19 lockdown caused a drop in load consumption and,consequently,a decrement in day-ahead market prices and an increase in ancillary service prices.

关键词： Ancillary service market price COVID-19 day-ahead market price Italian electricity markets load consumption

On the Proper Homotopy Invariance of the Tucker Property

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Acta mathematica Sinica,English Series 2007年第3期23卷 571-576页

作者： Daniele ettore OTERA Universitádi Palermo Dipartimento di Matematica ed Applicazionivia Archirafi 3490123-PalermoItaly and Université Paris-SudMathématiquesBt 42591405 Orsay Cedex-France

A non-compact polyhedron P is Tucker if, for any compact subset K begong to P, the fundamental group π1 （P - K） is finitely generated. The main result of this note is that a manifold which is proper homotopy equivalent to a Tucker polyhedron is Tucker. We use Poenaru＇s theory of the equivalence relations forced by the singularities of a non-degenerate simplicial map.

关键词： proper homotopy Φ/ψ-theory tucker property

Recent developments in Boolean networks control

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Journal of Control and Decision 2016年第1期3卷 1-18页

作者： ettore Fornasini maria Elena Valcher Dipartimento di Ingegneria dell’Informazione Universitàdi PadovaPadovaItaly

The aim of this survey paper is to provide the state of the art of the research on control and optimal control of Boolean control networks,under the assumption that all the state variables are accessible and hence available for *** and sufficient conditions for stabilisability to a limit cycle or to an equilibrium point are ***,it is shown that when such conditions are satisfied,stabilisation can always be achieved by means of state *** results are obtained for the safe control problem that is investigated for the first time in this *** and infinite horizon optimal control are subsequently considered,and solution algorithms are provided,based on suitable adaptations of theRiccati difference and algebraic ***,an appropriate definition of the cost function allows to restate and to solve both stabilisation and safe control as infinite horizon optimal control problems.

关键词： Boolean control networks algebraic representation controllability stabilisation optimal control safe control

Kinetics of defect formation in chemically vapor deposited （CVD） graphene during laser irradiation： The case of Raman investigation

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Nano Research 2015年第12期8卷 3972-3981页

作者： Giampiero Amato Gianluca Milano Umberto Vignolo ettore Vittone Quantum Research Laboratory INRIM Strada delle Cacce 91 Torino Italy Department of Physics NIS Research Center University of Torino via Pietro Giuria 1 10125 Torino Italy

激光照耀在上的效果化学上，蒸汽扔了(CVD ) graphene 被分析在各种各样的照明条件下面获得的拉曼系列的时间的进化学习。系列证明缺点相关的山峰的规范的紧张与暴露时间的方形的根增加并且与激光力量密度几乎线性地变化。而且，到放射... 详细信息

激光照耀在上的效果化学上，蒸汽扔了(CVD ) graphene 被分析在各种各样的照明条件下面获得的拉曼系列的时间的进化学习。系列证明缺点相关的山峰的规范的紧张与暴露时间的方形的根增加并且与激光力量密度几乎线性地变化。而且，到放射损坏的 graphene 的坚硬取决于它的内在的结构的质量。结果建议与普通信仰相反， micro-Raman 光谱学不能为 graphene 的描述被认为一个 noninvasive 工具。试验性的观察与我们在 hydrogenated 从 StaeblerWronski 效果的解释途径导出的一个模型兼容非结晶的硅；这条途径假设 photoexcited 搬运人的再结合导致碎弱 CC 契约。

关键词：缺陷形成激光辐照化学气相沉积石墨动力学显微拉曼光谱激光功率密度氢化非晶硅

Does kinship affect spatial organization in a small and isolated population of a solitary felid: The Eurasian lynx?

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Integrative Zoology 2016年第5期11卷 334-349页

作者： Krzysztof SCHMIDT Francesca DAVOLI Rafał KOWALCZYK ettore RANDI mammal Research Institute Polish Academy of SciencesBiałowieżaPoland Laboratory of Genetics Institute for Environmental Protection and ResearchOzzano EmiliaItaly Aalborg University Department of BiotechnologyChemistry and Environmental EngineeringAalborgDenmark

Social organization in wild carnivores is mostly determined by patterns of family bonds,which may shape the degree of relatedness among individuals in the *** studied kinship in a small and isolated population of a solitary carnivore,the Eurasian lynx(Lynx lynx)to evaluate its effect on spatial distribution of *** investigated the relationship between spatial location and pair-wise kinship among 28 lynx individuals identified in 2004-2011 by telemetry,non-invasive sampling and genotyping with the use of 12 autosomal microsatellites in the Białowieża Primeval Forest,*** average relatedness of the lynx population was relatively low(Lynch and Ritland’s R=0.03).Females were significantly more related to each other than males with other *** inferred pedigree showed that the population was dominated by only 2 familial *** did not find significant correlations between the relatedness and the extent of home range overlap or the straight-line distances between the home ranges’central *** results suggest that the dynamics of kinship in this solitary felid may not differ from the random mating processes described in social *** the chances of random mating could be limited to a few resident males and females,the presence of unrelated floaters may provide a“breeding buffer”that may prevent an increase of relatedness and likely inbreeding in the pop*** system is likely to fail in preserving genetic diversity in small,highly isolated populations;therefore,restoring habitat connectivity is crucial to ensure sufficient immigration from neighboring populations.

关键词： genetic variability inbreeding mating system relatedness social organization

Viability of thermal imaging in detecting nests of the invasive hornet Vespa velutina

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Insect Science 2021年第1期28卷 271-277页

作者： Simone Lioy ettore Bianchi Alessandro Biglia mattia Bessone Daniela Laurino marco Porporato Department of Agriculture Forest and Food SciencesUniversity of TurinGrugliasco(Turin)Italy School of Biological and Environmental Science Liverpool John Moores UniversityLiverpoolUK

Vespa velutina is an invasive hornet species that is colonising Europe,generating considerable impacts on honeybees,beekeeping and *** and early warning strategies for this species are mainly based on monitoring plans and procedures of nest detection and *** tools(harmonic radar,radio-telemetry)have been developed to increase the probabilities of nest detection in new *** hornets are able to regulate nest temperature,thermography may represent an additional technique that may be used,both alone or in support to other *** this study,the viability of thermal imaging in detecting nests of *** was evaluated in controlled *** influence of different environmental and operative variables(time of the day,presence/absence of leaves covering the nest,distance between the nest and the operator)were tested on three nests detected during August 2018 in *** the nests were detectable by thermal imaging,but environmental and operative variables affect their *** temperature difference between the nests and the surrounding reaches its maximum before sunrise and without a tree canopy covering the *** nests were visible in some cases from 30 m,the detectability was higher at shorter distances,even if this variable may also depend on infrared camera *** increase in the environmental temperature also generates a decrease of nest *** some limitations could occur,these results show the applicability of thermography in detecting V velutina nests before the beginning of the reproductive phase,and consequently its potentiality in control strategies.

关键词： alien species Asian yellow-legged hornet monitoring nest detection remote sensing thermography

A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor

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Asian Journal of Andrology 2022年第6期24卷 579-583页

作者： Francesco A Mistretta Ottavio de Cobelli Paolo Verze Francesco Botticelli Letizia Jannello Stefano Luzzago Gabriele Cozzi Roberto Bianchi ettore Di Trapani matteo Ferro Giovanni Cordima Danilo Bottero Deliu Victor matei Vincenzo Mirone Gennaro Musi Department of Urology European Institute of OncologyIRccSMilan 20141Italy Department of Oncology and Hemato-Oncology University of MilanMilan 20122Italy Department of Urology University of NaplesFederico IlNaples 80138Italy

Sexual disorders following retroperitoneal pelvic lymph node dissection(RPLND)for testis tumor can affect the quality of life of *** aim of the current study was to investigate several different andrological outcomes,which may be influenced by robot-assisted(RA)*** January 2012 to march 2020,32 patients underwent RA-RPLND for stage I nonseminomatous testis cancer or postchemotherapy(PC)residual *** unilateral RPLND nerve-sparing template was always *** variables of interest were erectile dysfunction(ED),premature ejaculation(PE),dry ejaculation(DE),or orgasm ***,fertility as well as the fecundation process(sexual intercourse or medically assisted procreation[maP])was *** patients(31.3%)presented an andrological disorder of any type after *** was present in 4(12.5%)patients,DE(International Index of Erectile Function-5[IIEF-5]mass index(BMI),number of nodes removed,scholar status,and preoperative risk factor rates were identified between *** all these 10 patients,6(60.0%)were treated at the beginning of our robotic experience(2012-2016).Of all 32 patients,5(15.6%)attempted to have a child after *** of these 5 patients have successfully fathered children,but 2(40.0%)required a *** conclusion,a nonnegligible number of andrological complications occurred after RA-RPLND,mainly represented by ejaculation disorders,but ED occurrence and overall sexual satisfaction deficit should be definitely *** negative impact on fertility was described after RA-RPLND.

关键词： andrology lymph node excision nonseminomatous germ cell tumor robotics testicular cancer