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Third-line and rescue therapy for refractory Helicobacter pylori infection: A systematic review

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World Journal of Gastroenterology 2023年第2期29卷 390-409页

作者： Pedro Vieira de Moraes Andrade Yan Mosca Monteiro ethel Zimberg Chehter Department of Gastroenterology Faculdade de Medicina do ABCSanto André09060-650SPBrazil

BACKGROUND Due to increasing resistance rates of Helicobacter pylori(***)to different antibiotics,failures in eradication therapies are becoming more *** though eradication criteria and treatment algorithms for first-line and second-line therapy against *** infection are well-established,there is no clear recommendation for third-line and rescue therapy in refractory *** *** To perform a systematic review evaluating the efficacy and safety of rescue therapies against refractory *** *** A systematic search of available rescue treatments for refractory *** infection was conducted on the National Library of Medicine’s PubMed search platform based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** or non-randomized clinical trials and observational studies evaluating the effectiveness of *** infection rescue therapies were *** Twenty-eight studies were included in the analysis of mean eradication rates as rescue therapy,and 21 of these were selected for analysis of mean eradication rate as third-line *** rifabutin-,sitafloxacin-,levofloxacin-,or metronidazole-based triple-therapy as third-line treatment,mean eradication rates of 81.6%and 84.4%,79.4%and 81.5%,55.7%and 60.6%,and 62.0%and 63.0%were found in intention-to-treat(ITT)and per-protocol(PP)analysis,*** third-line quadruple therapy,mean eradication rates of 69.2%and 72.1%were found for bismuth quadruple therapy(BQT),88.9%and 90.9%for bismuth quadruple therapy,three-in-one,Pylera®(BQT-Pylera),and 61.3%and 64.2%for non-BQT)in ITT and PP analysis,*** rifabutin-,sitafloxacin-,levofloxacin-,or metronidazole-based triple therapy as rescue therapy,mean eradication rates of 75.4%and 78.8%,79.4 and 81.5%,55.7%and 60.6%,and 62.0%and 63.0%were found in ITT and PP analysis,*** quadruple therapy as rescue treatment,mean eradication rates of 76.7%and 79.2%for BQT,

关键词： Helicobacter pylori Refractory infection Third-line therapy Rescue therapy Eradication Treatment

Building an interoperable space for smart agriculture

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Digital Communications and Networks 2023年第1期9卷 183-193页

作者： Ioanna Roussaki Kevin Doolin Antonio Skarmeta George Routis Juan Antonio Lopez-Morales ethel Claffey Manuel Mora Juan Antonio Martinez Institute of Communications and Computer Systems AthensGreece Walton Institute WaterfordIreland Department of Information and Communications Engineering University of MurciaMurciaSpain School of Business Waterford Institute of TechnologyWaterfordIreland R&D Department Odin SolutionsMurciaSpain

The digital transformation in agriculture introduces new challenges in terms of data,knowledge and technology adoption due to critical interoperability issues,and also challenges regarding the identification of the most suitable data sources to be exploited and the information models that must be ***(Building an Interoperable,Data-Driven,Innovative and Sustainable European Agri-Food Sector)addresses these challenges by providing an overarching solution that integrates various heterogeneous hardware and software resources(e.g.,devices,networks,platforms)and enables the seamless sharing of data and knowledge throughout the agri-food *** paper introduces the main concepts of DEMETER and its reference architecture to address the data sharing and interoperability needs of farmers,which is validated via two rounds of 20 large-scale pilots along the DEMETER *** paper elaborates on the two pilots carried out in region of Murcia in Spain,which target the arable crops sector and demonstrate the benefits of the deployed DEMETER reference architecture.

关键词： Smart agriculture Internet of things(IoT) DEMETER Reference architecture Interoperability Agricultural information model(AIM) Pilot validation

Co-host Cities of the Beijing Olympic Games

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China Today 2008年第8期57卷 48-57页

作者： ethel LU

IN August,Hong Kong,Qingdao, Tianjin,Shenyang,Shanghai and Qinhuangdao,as co-host cities of the Beijing Olympic Games, will respectively host the equestrian, sailing and soccer competitions.

关键词：北京奥运会协办城市香港青岛体育竞赛

Getting Around the Capital——Transport in Beijing

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China Today 2008年第8期57卷 14-17页

作者： ethel LU

THE number of motor vehicles in Beijing hit 3.2 million in February this year-almost double the figure of late *** the munici- pal government having spent some RMB 110 billion on improving traf- fic systems since Beijing was announced as the host city for the 2008 Olympics,an average day still sees chronic congestion in the *** August, hundreds of thousands of athletes,coaches,sports officials,media personnel and tourists will flood into Beijing,placing even more pressure on the city and poten- tially creating a major headache for residents as well as the government. Below is a guide *** your way around Beijing’s transport options and dodging the traffic.

关键词：北京奥运会交通运输城市建设

China Goes All Out to Ward off H1N1 Flu

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China Today 2009年第6期58卷 24-25页

作者： ethel LU

AFTER its debut in late March, A/H1N1 flu soon spread from Mexico and the U.S. to more than 30 countries and regions worldwide, including China’s mainland and Hong Kong, causing global alarm and prompting a flurry of... 详细信息

关键词：中国大陆禽流感病毒抵御世界卫生组织墨西哥

Radical Shifts in China’s Milk Market

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China Today 2009年第1期58卷 28-30页

作者： ethel LU

THE recent melamine scandal has bitten deep into China＇s milk industry, smearing a number of reputed domestic names and ruining the companies. Sanlu, the principal company implicated in the scandal, now faces bankrup... 详细信息

关键词：中国牛奶市场食品安全三聚氰胺

Beijing’s Olympic Venues Are Earthquake Proof

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China Today 2008年第8期57卷 58-59页

作者： ethel LU

WHEN the Wenchuan earth- quake struck on May 12, 2008,Li Jiulin,chief en- gineer with the Engineer Procurement Construction Department of the National Stadium,popularly known as the Bird’s Nest,was per-

关键词：北京奥运会比赛地点地震应急避难措施

Healthy Babies for HIV/AIDS Mothers

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China Today 2005年第8期54卷 37-39页

作者： ethel LU staff reporter

Clinical studies indicate that the risk of perinatal HIY/AIDS transmission, if not interrupted, is between 15 and 50 percent International statistics show that every year. there are 2.4 nillion HIV/AIDS infected pregn... 详细信息

关键词：艾滋病妇女防治措施中国

Making the Most of Every Cent in the Disaster Zone

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China Today 2008年第7期57卷 29-30页

作者： ethel LU staff reporter

MS. Chen is not rich by any standard Forbes would acknowledge, but like her ancient predecessor spoken of once in a parable, she is a modest woman more rich in generosity for having sacrificed a greater portion of what little she had to spare. ＂I do-nated my monthly pay of 3,000 yuan,＂ she said, without false modesty. ＂It is my largest donation yet.＂

关键词：中国汶川地震国际援助爱心捐款