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World Journal of Clinical Cases 2019年第6期7卷 753-758页

作者： Luis Pablo López Rivero Miguel Jaimes Felipe Camargo esther López-Bayghen Instituto de Infertilidad y Genética México SC Departamento de Toxicología Centro de Investigación de Estudios

BACKGROUND An isthmocele is a scar defect in the uterine wall due to a cesarean section. Its prevalence is unknown,but it has been associated with secondary ***,we present a case where the patient suffered from an isthmocele that was associated with persistent hydrometra,which developed during in vitro *** SUMMARY The patient underwent hysteroscopic surgery,which successfully resolved the isthmocele as well as the hydrometra. Afterward,two high-quality,euploid embryos,determined by morphological assessment and pre-implantation genetic diagnostic testing,were transferred. This resulted in uterine pregnancy,as determined byserum β-human chorionic gonadotropin levels on day 14(180 m U/mL) and ultrasound-confirmed presence of a gestational sac with a positive embryocardia at week 6. The pregnancy reached 36 wk without any complications,and the product was born in good health. We report a successful isthmocele treatment in a patient with secondary infertility,in which the isthmocele was the cause of persistent *** Hydrometra caused by secondary cesarean is an infertility factor,which can be corrected by hysteroscopy plus ablation of the isthmocele.

关键词： In vitro fertilization Isthmocele Hydrometra Case report

Prospects for ASEAN-China Free Trade Area:A Qualitative and Quantitative Analysis

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China & World Economy 2009年第4期17卷 104-120页

作者： Donghyun Park Innwon Park Gemma esther B.Estrada Economic and Research Department Asian Development Bank Division of International Studies Korea University

The current global financial and economic crisis is giving new life to initiatives that promote closer economic integration among East Asian countries. A significant example is the ASEAN- China Free Trade Area （.4 CFTA）, which is set to come into effect around 2010..4CFTA aims to boost trade between two economies that are partners as well as competitors： ASEAN and China. In the present paper, we use insights from customs union theory in a qualitative analysis considering whether,4CFTA would benefit both sides. We also apply a computable general equilibrium model to perform a quantitative analysis of the same issue. Both our qualitative and quantitative analyses provide grounds for guarded optimism regarding A CFTA ＇s prospects as a vehicle for strengthening the economic partnership between ASEAN and China.

关键词： ASEAN China computable general equilibrium model economic integration free trade area

Apoptosis in skeletal muscle and its relevance to atrophy

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World Journal of Gastroenterology 2006年第46期12卷 7463-7466页

作者： esther E Dupont-Versteegden University of Arkansas for Medical Sciences Departments of Geriatrics and Physiology and Biophysics 4301 West Markham #807 Little Rock AR 72205 and University of Kentucky Department of Rehabilitation Sciences Division of Physical Therapy 900 S Limestone Lexington KY 40536-0200 United States

Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal system. The role of apoptosis in post mitotic tissues, such as skeletal muscle, is less well defined. Apoptosis during muscle atrophy occurs in both myonuclei and other muscle cell types. Apoptosis of myonuclei likely contributes to the loss of muscle mass, but the mechanisms underlying this process are largely unknown. Caspase-dependent as well as -independent pathways have been implicated and the mode by which atrophy is induced likely determines the apoptotic mechanisms that are utilized. It remains to be determined whether a decrease in apoptosis will alleviate atrophy and distinct research strategies may be required for different causes of skeletal muscle loss.

关键词： Skeletal muscle Apoptosis Disuse atrophy Aging

Stable NiO-CeO_(2) nanoparticles with improved carbon resistance for methane dry reforming

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Journal of Rare Earths 2022年第1期40卷 57-62页

作者： Andrea Cárdenas-Arenas esther Bailón-García Dolores Lozano-Castelló Patrick Da Costa Agustín Bueno-López Department of Inorganic Chemistry University of AlicanteCarretera de San Vicente s/nE03080AlicanteSpain Sorbonne Universite Institut Jean Le Rond d'AlembertCNRS UMR 71902 place de la gare de ceinture78210Saint Cyr L'EcoleFrance

High surface area mixed oxide 8.7%NiO-CeO_(2) nanoparticles(122 m2/g;6-7 nm)were prepared using a reversed microemulsion method,and were tested for dry methane reforming(DRM).The catalytic activity of these nanoparticles remains stable under the severe conditions of DRM(700℃),and they show better carbon resistance than conventional NiO-CeO_(2) catalysts prepared without control of the *** activity and selectivity of nanoparticles and reference catalyst are similar,but nanoparticles reduce the accumulation of carbon by 63%during the DRM tests,which is a key feature for this *** and H_(2)-TPR suggest that the improved carbon resistance of the nanoparticles is due to the better interaction and cooperation between NiO and CeO_(2) mixed *** nanoparticles,the participation of cerium cations in the redox processes taking place during DRM stabilizes cationic species of *** the contrary,the catalyst prepared without control of the size suffers segregation of Ni during DRM reaction,and segregated Ni explains the higher catalytic formation of carbon.

关键词： Methane dry reforming Nickel Ceria Nanoparticle Rare earths

An overview of biomass solid fuels:Biomass sources,processing methods,and morphological and microstructural properties

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Journal of Bioresources and Bioproducts 2023年第4期8卷 333-360页

作者： Segun E.Ibitoye Rasheedat M.Mahamood Tien-Chien Jen Chanchal Loha esther T.Akinlabi Department of Mechanical Engineering Science Faculty of Engineering and the Built EnvironmentUniversity of JohannesburgAuckland Park2006524South Africa Department of Mechanical Engineering Faculty of Engineering and TechnologyUniversity of IlorinIlorin P.M.B.1515Nigeria Energy Research and Technology Group CSIR-Central Mechanical Engineering Research InstituteWest BengalDurgapur-713209India Department of Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle NE18STUnited Kingdom

Biomass solid fuel(BSF)has emerged as a promising renewable energy source,but its morphological and microstructural properties are crucial in determining their physical,mechanical,and chemical *** paper provides an overview of recent research on *** focus is on biomass sources,BSF processing methods,and morphological and microstructural properties,with a special emphasis on energy-related *** inclusion and exclusion criteria were established for the study to ensure *** inclusion criteria encompassed studies about BSFs and studies investigating the influence of biomass sources and processing methods on the morphological and microstructural properties of solid fuels within the past five *** technologies for converting biomass into usable energy were discussed,including gasification,torrefaction,carbonization,hydrothermal carbonization(HTC),and *** has advantages and disadvantages in energy performance,techno-economics,and climate *** is efficient but requires high *** produces bio-oil,char,and gases based on feedstock *** generates low-cost biochar for solid fuels and carbon sequestration *** increases energy density for co-firing with *** processes wet biomass efficiently with lower energy *** treatment affects BSF durability and strength,often leading to less durability due to voids and gaps between *** carbonization alters surface morphology,creating cavities,pores,and distinctive *** pyrolysis generates biochar with better morphological properties,while fast pyrolysis yields biochar with lower porosity and surface *** constitutes 67%of the biomass sources utilized for bioenergy generation,followed by wood residues(5%),agro-residues(4%),municipal solid wastes(3%),energy crops(3%),livestock wastes(3%),and forest residues(1%).Each source has advantages and drawbacks,such as avail

关键词： Biomass feedstock Microstructural property Morphological property Renewable energy Thermal treatment

Application of the Population Health Approach to Drinking Water System Surveillance

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环境与职业医学 2007年第1期24卷 117-119页

作者： Deborah Kelly Barnard esther Parker Ann Thomas Population Health Epidemiologist Population Health Surveillance Unit

A drinking water supply is a complicated system in its construction,operation,maintenance and need for public health surveillance.

关键词： drinking water surveillance british columbia canada

More Transporters,More Substrates:The Arabidopsis Major Facilitator Superfamily Revisited

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Molecular Plant 2019年第9期12卷 1182-1202页

作者： Maria Nino-Gonzalez esther Novo-Uzal Dale N.Richardson Pedro M.Barros Paula Duque Instituto Gulbenkian de Ciencia 2780-156 OeirasPortugal Genomics of Plant Stress Unit ITQB NOVA-Instituto de Tecnologia Quimica e Biologica Antonio XavierUniversidade Nova de Lisboa2780-157 OeirasPortugal

The Major Facilitator Superfamily(MFS)is ubiquitous in living organisms and represents the largest group of secondary active membrane *** plants,significant research efforts have focused on the role of specific families within the MFS,particularly those transporting macronutrients(C,N,and P)that constitute the vast majority of the members of this *** MFS families remain less explored,although a plethora of additional substrates and physiological functions have been ***,the lack of a systematic approach to analyzing the MFS as a whole has obscured the high diversity and versatility of these ***,we present a phylogenetic analysis of all annotated MFS domaincontaining proteins encoded in the Arab/dops/s fA?a//ana genome and propose that this superfamily of transporters consists of 218 members,clustered in 22 *** reviewing the available information regarding the diversity in biological functions and substrates of Arab/dops/s MFS members,we provide arguments for intensified research on these membrane transporters to unveil the breadth of their physiological relevance,disclose the molecular mechanisms underlying their mode of action,and explore their biotechnological potential.

关键词： Arabidopsis thaliana membrane transport MFS transporters phylogenetic analysis

Split-root systems applied to the study of the legume-rhizobial symbiosis: What have we learned?

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Journal of Integrative Plant Biology 2014年第12期56卷 1118-1124页

作者： Estíbaliz Larrainzar Erena Gil-Quintana Cesar Arrese-Igor esther M.González Daniel Marino Department of Environmental Sciences Public University of Navarra Pamplona E-31006 Spain Department of Plant Biology and Ecology University of the Basque Country UPV/EHU Bilbao E-48080 Spain Ikerbasque Basque Foundation for Science Bilbao E-48011 Spain

Split-root system（SRS） approaches allow the differential treatment of separate and independent root systems, while sharing a common aerial part. As such, SRS is a useful tool for the discrimination of systemic（shoot origin）versus local（root/nodule origin） regulation mechanisms. This type of approach is particularly useful when studying the complex regulatory mechanisms governing the symbiosis established between legumes and Rhizobium bacteria. The current work provides an overview of the main insights gained from the application of SRS approaches to understand how nodule number（nodulation autoregulation） and nitrogen fixation are controlled both under non-stressful conditions and in response to a variety of stresses. Nodule number appears to be mainly controlled at the systemic level through a signal which is produced by nodule/root tissue, translocated to the shoot, and transmitted back to the root system, involving shoot Leu-rich repeat receptor-like kinases. In contrast, both local and systemic mechanisms have been shown to operate for the regulation of nitrogenase activity in nodules. Under drought and heavy metal stress, the regulation is mostly local,whereas the application of exogenous nitrogen seems to exert a regulation of nitrogen fixation both at the local and systemic levels.

关键词： legume-rhizobia nitrogen fixation nodulation split-root system symbiosis

Model–proxy comparison for overshoot phenomenon of Atlantic thermohaline circulation at Bφlling–Allerφd

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Chinese Science Bulletin 2014年第33期59卷 4510-4515页

作者： Jun Cheng Zhengyu Liu Feng He Bette Otto-Bliesner esther Brady Jean Lynch-Stieglitz Polar Climate System and Global Change Laboratory and Earth System Modeling Center (ESMC) Nanjing International Academy of Meteorological Sciences (NIAMS) Nanjing University of Information Science and Technology Department of Atmospheric and Oceanic Sciences Center for Climatic Research University of Wisconsin-Madison LaCOAS/Department of Atmospheric and Oceanic Sciences Peking University Climate and Global Dynamics Division National Center for Atmospheric Research School of Earth and Atmospheric Sciences Georgia Institute of Technology

The overshoot phenomenon of the Atlantic thermohaline circulation(THC) is a transient climate response to meltwater forcing and could induce intense climate change by increasing the magnitudes of Atlantic THC changes at the end of meltwater discharges. This phenomenon was formally presented with the successfully simulated Bφlling–Allerφd(BA) event in the first transient simulation of the last deglaciation with fully coupled model NCAR-CCSM3(TraCE-21K). Currently, not all proxy records of Atlantic THC support the occurrence of the THC overshoot at BA. Commonly used THC proxy from Bermuda Rise(GGC5) does not exhibit THC overshoot at BA but other proxies such as TTR-451 at Eirik Drift do. How to interpret this regional discrepancy of proxy records is a key question for the validation of the Atlantic THC overshoot at BA. Here, we show that the vigor of deep circulation varies regionally during the Atlantic THC overshoot at BA in TraCE-21 K simulation, and this regional discrepancy in the simulation is consistent with that in the marine sediment records in North Atlantic. The consistent model–proxy evidence supports the occurrence of Atlantic THC overshoot at BA.

关键词：北大西洋过冲现象温盐环流代理模型模拟过程 THC 气候变化

Crowdfunding Effort Identifies the Causative Mutation in a Patient with Nystagmus,Microcephaly,Dystonia and Hypomyelination

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Journal of Genetics and Genomics 2015年第2期42卷 79-81页

作者： Ofer Isakov Dorit Lev Lubov Blumkin Gershon Celniker esther Leshinsky-Silver Noam Shomron Sackler School of Medicine Tel Aviv University Metabolic-Neurogenetic Clinic Wolfson Medical Center Institute of Medical Genetics Wolfson Medical Center Pediatric Neurology Unit Wolfson Medical Center Molecular Genetic Laboratory Wolfson Medical Center

Crowdfunding refers to the online gathering of finance via numerous small donations from individual supporters （the ＂crowd＂） in order to fund a service, project or cause from various fields including business, arts, medicine and science （Sisler, 2012; Cameron et al., 2013; Weigmann, 2013; Wheat et al., 2013）. Crowdfunding platforms facilitate the interaction between organizations soliciting funding for their projects and the people who wish to support them. As prices of molecular testing plummet, utilizing crowdfunding in order to support genetic research becomes increasingly feasible （Cameron et al., 2013）. Whole Exome Sequencing （WES） has been used extensively for the purpose of identifying the genetic cause of rare mendelian diseases, uncovering novel mutations in previously implicated genes or identifying new disease- causing genes （Ng et al., 2009; Bamshad et al., 2011; Gilissen et al., 2011）.

关键词： PHENOTYPE EXPANSION SPECTRUM