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Polysaccharide from Astragalus membranaceus promotes the activation of human peripheral blood and mouse spleen dendritic cells

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Chinese Journal of Natural Medicines 2021年第1期19卷 56-62页

作者： lim.Seong-Min Park Hae-Bin Jin Jun-o Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541South Korea Shanghai Public Health Clinical Center Shanghai Medical CollegeFudan UniversityShanghai201508China

Astragalus membranaceus(***)is a widely used traditional herb in China and *** polysaccharides(AMP),which make up a major part of the root extract,have been shown to modulate immune modulations,especially activation of bone marrow-derived dendritic cells(BMDCs)and T ***,the immune stimulatory effect of AMP in the mouse in vivo and human peripheral blood DCs(PBDCs)has not been well *** this study,we found that intravenous(i.v.)injection of AMP in C57 BL/6 mice induced remarkable elevations in co-stimulatory and MHC class I and II molecule levels in the splenic DCs and its *** stimulatory effect of DCs by AMP was elevated 6 h after treatment,which rapidly decreased 18 h after ***,AMP promoted intracellular production of pro-inflammatory cytokines in spleen DC subsets,which contributed elevation of serum cytokine ***,the AMP promoted PBDC ***,these results demonstrate that AMP can be used as an immune stimulatory molecules in human and mouse.

关键词： Astragalus membranaceus polysaccharide Spleen dendritic cell Human peripheral blood dendritic cell

A Quantum Network System of QSS-QDC Using χ-Type Entangled States

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Chinese Physics Letters 2012年第5期29卷 22-25页

作者： Chang Ho Hong Jin o Heo Jong in lim.Hyung jin Yang Graduate School of Information Management and Security Korea UniversitySungbuk-gu Anam 5-gaSeoulSouth Korea Center for Information Security Technologies(CIST) Korea UniversitySeoulSouth Korea Department of Physics Korea UniversityChochiwonChoongnamSouth Korea

A multiuser quantum direct communication network system for N users utilizing χ-type entangled states is prupused. The network system is composed of a communication center,N users,and N quantum lines linking the center and the N *** is no quantum line among users,and therefore only N quantum lines are necessary for communication between *** one χ-type entangled state, in this protocol we are able to send two bits of information through direct communication and,at the same time,share two bits of quantum keys. The security of the protocol is then analyzed.

关键词： quantum system utilizing

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Microbiology 2nd ed.

Microbiology

Integrative multi-omics and systems bioinformatics in translational neuroscience:A data mining perspective

1998年

作者： Daniel V lim.

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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Journal of Pharmaceutical Analysis 2023年第8期13卷 836-850页

作者： Lance M.o'Connor Blake A.o'Connor Su Bin lim.Jialiu Zeng Chih Hung Lo College of Biological Sciences University of MinnesotaMinneapolisMN55455USA School of Pharmacy University of WisconsinMadisonWI53705USA Department of Biochemistry and Molecular Biology Ajou University School of MedicineSuwon16499South Korea Lee Kong Chian School of Medicine Nanyang Technological UniversitySingapore308232Singapore

Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed *** mining of omics datasets has enabled the generation of new hypotheses based on differentially regulated biological molecules associated with disease mechanisms,which can be tested experimentally for improved diagnostic and therapeutic targeting of neurodegenerative ***,integrating multi-omics data using a systems bioinformatics approach will advance the understanding of the layered and interactive network of biological regulation that exchanges systemic knowledge to facilitate the development of a comprehensive human brain *** this review,we first summarize data mining studies utilizing datasets from the individual type of omics analysis,including epigenetics/epigenomics,transcriptomics,proteomics,metabolomics,lipidomics,and spatial omics,pertaining to Alzheimer's disease,Parkinson's disease,and multiple *** then discuss multi-omics integration approaches,including independent biological integration and unsupervised integration methods,for more intuitive and informative interpretation of the biological data obtained across different omics *** further assess studies that integrate multi-omics in data mining which provide convoluted biological insights and offer proof-of-concept proposition towards systems bioinformatics in the reconstruction of brain ***,we recommend a combination of high dimensional bioinformatics analysis with experimental validation to achieve translational neuroscience applications including biomarker discovery,therapeutic development,and elucidation of disease *** conclude by providing future perspectives and opportunities in applying integrative multi-omics and systems bioinformatics to achieve precision phenotyping of neurodegenerative diseases and towards personaliz

关键词： Multi-omics integration Systems bioinformatics Data mining Human brain profile reconstruction Translational neuroscience

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评价热门的电压放大管6SN7

高保真音响 1997年第1期 42-44页

作者： lim.,MK

如何降低DYNACo PAS3 前级的交流声和噪声

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高保真音响 1998年第6期 54-55页

作者： lim.,MK

Characterizations of organic compounds in diesel exhaust particulates

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Journal of Environmental Sciences 2015年第8期27卷 171-183页

作者： Jaehyun lim.Cheolsoo lim.Sangkyun Kim Jihyung Hong Division of Global Environment Research National Institute of Environmental Research Department of Clim.te and Air Quality Research National Institute of Environmental Research

To characterize how the speed and load of a medium-duty diesel engine affected the organic compounds in diesel particle matter（PM） below 1 μm, four driving conditions were examined. At all four driving conditions, concentration of identifiable organic compounds in PM ultrafine（34–94 nm） and accumulation（94–1000 nm） modes ranged from 2.9 to 5.7 μg/m3 and 9.5 to 16.4 μg/m3, respectively. As a function of driving conditions, the non-oxygencontaining organics exhibited a reversed concentration trend to the oxygen-containing organics. The identified organic compounds were classified into eleven classes： alkanes,alkenes, alkynes, aromatic hydrocarbons, carboxylic acids, esters, ketones, alcohols, ethers,nitrogen-containing compounds, and sulfur-containing compounds. At all driving conditions,alkane class consistently showed the highest concentration（8.3 to 18.0 μg/m3） followed by carboxylic acid, esters, ketones and alcohols. Twelve polycyclic aromatic hydrocarbons（PAHs）were identified with a total concentration ranging from 37.9 to 174.8 ng/m3. In addition, nine nitrogen-containing polycyclic aromatic compounds（NPACs） were identified with a total concentration ranging from 7.0 to 10.3 ng/m3. The most abundant PAH（phenanthrene）and NPACs（7,8-benzoquinoline and 3-nitrophenanthrene） comprise a similar molecular（3 aromatic-ring） structure under the highest engine speed and engine load.

关键词： Diesel particle matter organic compounds Polycyclic aromatic hydrocarbons Nitrogen-containing polycyclic aromatic compounds

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自制动图唱头放大器

高保真音响 1997年第8期 57-58页

作者： lim.,MK

Landau damping of twisted waves in Cairns distribution with anisotropic temperature

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Plasma Science and Technology 2021年第8期23卷 18-28页

作者： Sunggeun LEE Hankwon lim School of Energy and Chemical Engineering UNIST50UNIST-gilEonyang-eupUlju-gunUlsan 44919Republic of Korea

The consideration of orbital angular momentum of an electric field(twisted mode)is applied to the kinetic theory of *** linearized Vlasov–Poisson equation is solved for the anisotropic thermal distributed bi-Maxwellian and Cairns distributions of electrons to obtain the damping rates of twisted *** dispersion relation and Landau damping of Langmuir twisted modes are *** presence of twisted modes opens up two more possibilities in Landau damping and dispersion *** may generate a mixture with ion sound *** seems to play the role of a control parameter of Landau damping.

关键词： Landau damping Cairns distribution function anisotropic