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Evaluating mechanism and severity of injuries among trauma patients admitted to Sina Hospital,the National Trauma Registry of Iran

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Chinese Journal of Traumatology 2021年第3期24卷 153-158页

作者： Mina Saeednejad Mohammadreza Zafarghandi Narjes Khalili Vali Baigi Moein Khormali Zahra Ghodsi Mahdi Sharif-Alhoseini Reilly Gerard M.O’ Khatereh Naghdi Melika Khaleghi-Nekou Seyed mohammad Piri Vafa Rahimi-Movaghar Somayeh Bahrami Marjan Laal Mahdi Mohammadzadeh esmaeil Fakharian Habibollah Pirnejad Hamid Pahlavanhosseini Payman Salamati Homayoun Sadeghi-Bazargani Sina Trauma and Surgery Research Center Tehran University of Medical SciencesTehranIran Preventive Medicine and Public Health Research Center Department of Community and Family MedicineSchool of MedicineIran University of Medical SciencesTehranIran National Health and Medical Research Council(NHMRC) AustraliaNational Trauma Research InstituteThe Alfred Hospital and Monash UniversityMelbourneAustralia Trauma Research Center Kashan University of Medical SciencesKashanIran Patient Safety Research Center Urmia University of Medical SciencesUrmiaIran Trauma Research Center Shahid Sadoughi University of Medical SciencesYazdIRIran Road Traffic Injury Research Center Tabriz University of Medical SciencesTabrizIran

Purpose:Injuries are one of the leading causes of death and lead to a high social and financial *** patterns can vary significantly among different age groups and body *** study aimed to evaluate the relationship between mechanism of injury,patient comorbidities and severity of ***:The study included trauma patients from July 2016 to June 2018,who were admitted to Sina Hospital,Tehran,*** inclusion criteria were all injured patients who had at least one of the following:hospital length of stay more than 24 h,death in hospital,and transfer from the intensive care unit of another *** collection was performed using the National Trauma Registry of Iran minimum ***:The most common injury mechanism was road traffic injuries(49.0%),followed by falls(25.5%).The mean age of those who fell was significantly higher in comparison with other mechanisms(p<0.001).Severe extremity injuries occurred more often in the fall group than in the vehicle collision group(69.0%vs.43.5%,p<0.001).Moreover,cases of severe multiple trauma were higher amongst vehicle collisions than injuries caused by falls(27.8%vs.12.9%,p=0.003).Conclusion:Comparing falls with motor vehicle collisions,patients who fell were older and sustained more extremity *** injured by motor vehicle collision were more likely to have sustained multiple trauma than those presenting with *** of the relationship between mechanisms and consequences of injuries may lead to more effective interventions.

关键词： Wounds and injuries Multiple trauma Abbreviated injury scale Injury severity score Registries

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以冠状动脉钙化密度和形态预测心血管事件：Framingham心脏研究的见解

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国际医学放射学杂志 2020年第1期 120-120页

作者： B.Foldyna P.eslami J.Scholtz K.Baltrusaitis M.T.Lu J.M.Massaro 张立武 Cardiac MR PET CT Program Massachusetts General Hospital Harvard Medical School

目的采用CT研究冠状动脉钙化(CAC)的密度和形态与心血管病(CVD)事件之间的相关性。方法纳入2002—2005年Framingham心脏研究(FHS)进行心脏CT时

关键词：冠状动脉钙化 CVD CAC 心血管事件 Framingham 形态预测

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ABI-007,一种不用聚氧乙基代蓖麻油,蛋白质稳定的紫杉醇纳米制剂Ⅰ期临床和药物动力学的研究

ABI-007,一种不用聚氧乙基代蓖麻油,蛋白质稳定的紫杉醇纳米制剂...

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作者： Nuhad K.Ibrahim Neil Desai Sewa Legha Patrick Soon-Shiong Richard L.Theriault Edgardo Rivera Bita esmaeil Sigrid E.Ring Agop Bedikian Gabriel N.Hortobagyi Julie A Ellerhorst 乳腺肿瘤医学系

目的:ABI-007是一种不用聚氧乙基代蓖麻油(Cremophor E1),且蛋白质稳定的紫杉醇纳米制剂。不使用聚氧乙基代蓖麻油Cremophor EI可使ABI-007给药前不用进行常规预防超敏反应的预处理。此外,这种新制剂可使得紫杉醇在溶液中以更高的浓度存...

目的:ABI-007是一种不用聚氧乙基代蓖麻油(Cremophor E1),且蛋白质稳定的紫杉醇纳米制剂。不使用聚氧乙基代蓖麻油Cremophor EI可使ABI-007给药前不用进行常规预防超敏反应的预处理。此外,这种新制剂可使得紫杉醇在溶液中以更高的浓度存在,这样就可以减少输液的体积和时间,I期临床试验是要研究ABI-007的毒性,最大耐药剂量(MTD)和药物动力学。实验设计:ABI-007在门诊病人中使用,病人不用预先用药,30分钟滴注。ABI-007的剂量范围是从135(0级)到375mg/m2(3级)。16个病人参加了药物动力学的研究。结果:十九个病人在进行输液治疗期间没有观察到急性超敏反应。血药毒性是缓和的且无而非蓄积性。以3级(375mg/m2)治疗的6个病人中的3人发生剂量限制性毒性,口腔粘膜炎有2个病人,2个病人出现轻微的角膜炎。因此最大耐受剂量定为300 mg/m2(2级)。药物动力学分析显示当ABI-007的剂量在135-300mg/m2范围内时紫杉醇的Cmax和曲线下面积线形增加,Cmax和曲线下面积与病人个体毒性呈现出很好的相关性。结论:ABI-007提供了几个临床研究感兴趣的方面,包括快速输液率,不用预先用药处理和较高的紫杉醇最大耐药剂量,我们的研究结果为II期临床试验提供了该药抗肿瘤活性的依据。

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睑板腺囊肿

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英国医学杂志中文版 2010年第6期13卷 379-379页

作者： esmaeil M Arbabi Ross J Kelly Zia I Carrim 张吟眉(译) 不详北京大学第三医院检验科

21岁女性患者，主诉右侧上眼睑无痛肿物。肿物已经出现了几周，且在缓慢增大。她的医师建议她使用抗生素眼膏治疗，但使用了几天症状并无改善。

关键词：睑板腺囊肿抗生素眼膏女性患者上眼睑肿物

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采用噬菌体库发现抗白癜风抗体特异性多肽

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世界核心医学期刊文摘（皮肤病学分册） 2006年第2期2卷 47-47页

作者： Jadali Z. eslami M.B. Sanati M.H. 冯义国 PO Box 6446 Tehran 14155 IranDr.

Patients with vitiligo produce specific autoantibodies that can be detected in their sera. These antibodies are believed to play a role in the pathogenesis of this disease. A random peptide library displayed on phage is a technique that can be used to identify the epitopes that react with monoclonal and polyclonal antibodies. We used this technique to identify the epitopes that react specifically with the vitiligo autoantibodies. By screening the random peptide phage library and using ELISA, two clones that showed a higher frequency of reactivity with the antibodies in the sera of patients with vitiligo were identified. The peptides do not show any similarity with the autoantigens so far implicated in vitiligo, indicating that these epitopes may mimic conformational epitopes in proteins.

关键词：抗体特异性噬菌体展示抗原表位抗体反应特异性自身抗体自身抗原特异性反应发病机制

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Fungal diversity notes 1387-1511:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2021年第6期111卷 1-335页

作者： Saranyaphat Boonmee Dhanushka N.Wanasinghe Mark S.Calabon Naruemon Huanraluek Sajini K.U.Chandrasiri Gareth E.B.Jones Walter Rossi Marco Leonardi Sanjay K.Singh Shiwali Rana Paras N.Singh Deepak K.Maurya Ajay C.Lagashetti Deepika Choudhary Yu-Cheng Dai Chang-Lin Zhao Yan-Hong Mu Hai-Sheng Yuan Shuang-Hui He Rungtiwa Phookamsak Hong-Bo Jiang María P.Martín Margarita Dueñas MTeresa Telleria Izabela L.Kałucka Andrzej M.Jagodziński Kare Liimatainen Diana S.Pereira Alan J.L.Phillips Nakarin Suwannarach Jaturong Kumla Surapong Khuna Saisamorn Lumyong Tarynn B.Potter Roger G.Shivas Adam H.Sparks Niloofar Vaghefi Mohamed A.Abdel-Wahab Faten A.Abdel-Aziz Guo-Jie Li Wen-Fei Lin Upendra Singh Rajendra P.Bhatt Hyang Burm Lee Thuong T.T.Nguyen Paul M.Kirk Arun Kumar Dutta Krishnendu Acharya VVenkateswara Sarma M.Niranjan Kunhiraman C.Rajeshkumar Nikhil Ashtekar Sneha Lad Nalin N.Wijayawardene Darbe J.Bhat Rong-Ju Xu Subodini N.Wijesinghe Hong-Wei Shen Zong-Long Luo Jing-Yi Zhang Phongeun Sysouphanthong Naritsada Thongklang Dan-Feng Bao Janith V.S.Aluthmuhandiram Jafar Abdollahzadeh Alireza Javadi Francesco Dovana Muhammad Usman Abdul Nasir Khalid Asha J.Dissanayake Anusha Telagathoti Maraike Probst Ursula Peintner Isaac Garrido-Benavent Lilla Bóna Zsolt Merényi Lajos Boros Bratek Zoltán JBenjamin Stielow Ning Jiang Cheng-Ming Tian esmaeil Shams Farzaneh Dehghanizadeh Adel Pordel Mohammad Javan-Nikkhah Teodor T.Denchev Cvetomir M.Denchev Martin Kemler Dominik Begerow Chun-Ying Deng Emma Harrower Tohir Bozorov Tutigul Kholmuradova Yusufjon Gafforov Aziz Abdurazakov Jian-Chu Xu Peter E.Mortimer Guang-Cong Ren Rajesh Jeewon Sajeewa S.N.Maharachchikumbura Chayanard Phukhamsakda Ausana Mapook Kevin D.Hyde Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand CAS Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China CIFOR-ICRAF China Program World Agroforestry(ICRAF)Kunming 650201YunnanPeople’s Republic of China Honghe Center for Mountain Futures Kunming Institute of BotanyHonghe CountyKunming 654400YunnanPeople’s Republic of China Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia Section Environmental Sciences Department MeSVAUniversity of L’Aquila67100 CoppitoAQItaly National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology GroupMACS Agharkar Research InstituteG.G.Agarkar RoadPune 411004India Institute of Microbiology School of Ecology and Nature ConservationBeijing Forestry UniversityBeijing 100083People’s Republic of China College of Biodiversity Conservation Southwest Forestry UniversityKunming 650224People’s Republic of China CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110164People’s Republic of China University of the Chinese Academy of Sciences Beijing 100049People’s Republic of China Centre for Mountain Futures(CMF) Kunming Institute of BotanyKunming 650201YunnanPeople’s Republic of China Department of Mycology Real Jardín Botánico-CSICPlaza de Murillo 228014 MadridSpain Department of Algology and Mycology Faculty of Biology and Environmental ProtectionUniversity of LodzBanacha 12/1690-237ŁódźPoland Institute of Dendrology Polish Academy of SciencesParkowa 562-035 KórnikPoland Jodrell Laboratory Royal Botanic GardensKewRichmond TW93DSSurreyUK Faculdade de Ciências Biosystems and Integrative Sciences Institute(BioISI)Universidade de LisboaCampo Grande1749-016 LisbonPortugal Dep

This article is the 13th contribution in the Fungal Diversity Notes series,wherein 125 taxa from four phyla,ten classes,31 orders,69 families,92 genera and three genera incertae sedis are treated,demonstrating worldwide and geographic *** taxa described and illustrated in the present study include three new genera,69 new species,one new com-bination,one reference specimen and 51 new records on new hosts and new geographical *** new genera,Cylindrotorula(Torulaceae),Scolecoleotia(Leotiales genus incertae sedis)and Xenovaginatispora(Lindomycetaceae)are introduced based on distinct phylogenetic lineages and unique *** described species are Aspergillus lan-naensis,Cercophora dulciaquae,Cladophialophora aquatica,Coprinellus punjabensis,Cortinarius alutarius,***-latus,***,Coryneum fagi,Cruentomycena uttarakhandina,Cryptocoryneum rosae,Cyathus uniperidiolus,Cylindrotorula indica,Diaporthe chamaeropicola,Didymella azollae,Diplodia alanphillipsii,Dothiora coronicola,Efibula rodriguezarmasiae,Erysiphe salicicola,Fusarium queenslandicum,Geastrum gorgonicum,***,Helicosporium sexualis,Helminthosporium chiangraiensis,Hongkongmyces kokensis,Hydrophilomyces hydraenae,Hygrocybe boertmannii,Hyphoderma australosetigerum,Hyphodontia yunnanensis,Khaleijomyces umikazeana,Laboulbenia divisa,Laboulbenia triarthronis,Laccaria populina,Lactarius pallidozonarius,Lepidosphaeria strobelii,Longipedicellata megafusiformis,Lophiotrema lincangensis,Marasmius benghalensis,***,***,Mariannaea camelliae,Mel-anographium smilaxii,Microbotryum polycnemoides,Mimeomyces digitatus,Minutisphaera thailandensis,Mortierella solitaria,Mucor harpali,Nigrograna jinghongensis,Odontia huanrenensis,***,Paraconiothyrium ajrekarii,Par-afuscosporella niloticus,Phaeocytostroma yomensis,Phaeoisaria synnematicus,Phanerochaete hainanensis,Pleopunctum thailandicum,Pleurotheciella dimorphospora,Pseudochaetosphaeronema

关键词： 72 new taxa One new combination One reference specimen 51 new records Agaricomycetes Ascomycota Bartheletiomycetes Basidiomycota Dothideomycetes Eurotiomycetes Exobasidiomycetes Laboulbeniomycetes Leotiomycetes Mortierellomycetes Mortierellomycota Mucoromycetes Mucoromycota Phylogeny Sordariomycetes Taxonomy

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