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作者： (美)比尔·伯林霍夫(William P. Berlinghoff)，费尔南多·辜维亚(fernando Q. Gouvea)

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附文：沙门菌的特性和防控方法

国外畜牧学(猪与禽) 2021年第1期41卷 41-41页

作者： fernando Lozano 诗华动物保健公司

1沙门菌的特性

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冰雹结构异质性的分析:大气条件及其潜在的环境意义

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AMBIO-人类环境杂志 2001年第7期30卷 452-454页

作者： Jesús Martínez-Frías Millán Millán Nicolás García fernando López-Vera Antonio Delgado Roberto García 闵庆文 Departamento de Geologia Museo Nacional de Ciencias Naturales CSIC Jos Gutirraez Abascal 228006 Madrid Spain Jos A. Rodrguez-Losada Emilio Reyes Juan A. Martn Rub Aurora Gmez-Coedo

冰雹是球状或不规则冰块形式的降水,它一般产生于与复合单体、超级单体和冷锋锋面有关的对流云中。冰雹开始时是一些微小的冰球,这些小冰球与周围的小水滴不断发生碰撞,当附着的小水滴冻结起来,这些小冰球就增大了。当一个冰块混合体的... 详细信息

冰雹是球状或不规则冰块形式的降水,它一般产生于与复合单体、超级单体和冷锋锋面有关的对流云中。冰雹开始时是一些微小的冰球,这些小冰球与周围的小水滴不断发生碰撞,当附着的小水滴冻结起来,这些小冰球就增大了。当一个冰块混合体的直径达到或超过5 mm时,就称为雹块。一般来说,雹块是存在过冷水滴的雷暴积雨云内部上升气流和下沉气流共同作用的结果。过冷却的水滴不断沉积在冰晶上,使其起生长为雹块,这一般经过了从软雹(第一阶段)到小冰雹、再到雹块的不同阶段。一个雹块在

关键词：冰雹固态降水雹块对流层顶对流层上限低层大气大气条件异质性

Enzymatic vitrectomy for diabetic retinopathy and diabetic macular edema

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World Journal of Diabetes 2013年第6期4卷 319-323页

作者： Manuel Diaz-Llopis Patricia Udaondo Jose Maria Millán J fernando Arevalo Department of Ophthalmology University and Polytechnic Hospital La Fe of Valencia46009 ValenciaSpain Department of Genetics Hospital Universitario La Fe of Valencia46009 ValenciaSpain Retina Division Wilmer Eye InstituteJohns Hopkins University School of MedicineBaltimoreMD 21231United States King Khaled Eye Specialist Hospital Riyadh 11462Saudi Arabia

The aim of this paper is to determine the role of enzymatic vitrectomy performed by intravitreal injection of autologous plasmin enzyme(APE)in the management of diabetic retinopathy and diabetic macular edema(DME).Diabetic patients with proliferative diabetic retinopathy or DME and evident posterior hyaloid adherence to the retinal surface were *** cases were treated with an initial intravitreal injection of APE and reevaluated one month later,measuring changes in best-corrected visual acuity(BCVA),macular thickness and the status of the posterior hyaloid.A second APE injection was performed in cases with no evident posterior vitreous detachment(PVD)after the initial ***-three eyes were included in the present review.A complete PVD appeared in 38%of cases(24 eyes)after one injection of plasmin and the total increased to 51%(32 eyes)after the second injection,separated at least by one *** central macular thickness improved in all cases(100%)and BCVA in89%.Finally,in 50%of eyes with proliferative diabetic retinopathy,a high reduction of new vessels regression was *** vitrectomy could be considered a good therapeutic alternative in diabetic retinopathy and macular edema.

关键词： Enzymatic vitrectomy Autologous plasmin Diabetic macular edema Diabetic retinopathy

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古巴的有机农业运动

Implementation of a Telechemotherapy Module in the Peruvian Jungle with Adequate Quality of Life:Breaking the Access Gaps to Health with Teleoncology

农业经济研究 2010年第8期

作者： fernando Funes

在历史大背景和古巴政府发起的现代改革的前提下，古巴意识到替代传统农业模式的必要。20世纪90年代，古巴有机农业协会的形成小组(ACAO)在推动古巴有机农业方面发挥了巨大作用，众多研究中心多年的研究成果与农民积累的大量经验也为有... 详细信息

在历史大背景和古巴政府发起的现代改革的前提下，古巴意识到替代传统农业模式的必要。20世纪90年代，古巴有机农业协会的形成小组(ACAO)在推动古巴有机农业方面发挥了巨大作用，众多研究中心多年的研究成果与农民积累的大量经验也为有机农业的发展奠定基础。古巴在有机肥料、土壤保持、作物与畜禽管理等方面均取得重要成果，它推行的全国都市农业计划、小型水稻生产普及等成功经验，使古巴的有机农业转变堪称典范。如今的古巴已完成替代依赖于投入的农业模式的目标，在未来要面临的挑战是要建立更加复杂的生态农业体系。

关键词：有机农业生态农业合作社可持续 organic agriculture ecological agriculture co-operatives sustainability

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Journal of Cancer Therapy 2019年第8期10卷 677-691页

作者： Tatiana Vidaurre Jule Vásquez fernando Valencia Cindy Alcarraz Luis Más Nataly Poma Litol Becerra Gino Rodriguez Socorro Saldana Pepe Diaz Silvia Neciosup Karina Aliaga Roxana Regalado Miriam Salazar Kavita Sarwal Simon Sutcliffe Julio Abugattas Carlos Castaneda Mónica Calderón Hugo Fuentes Henry Gómez Medical Oncologist Instituto Nacional de Enfermedades Neoplasicas(INEN)LimaPeru Hospital II-E Lamas San MartinPeru Instituto Nacional de Enfermedades Neoplasicas(INEN) LimaPeru International Cancer Control Congress Association(ICCCA) VancouverCanada

Background: Cancer is a leading cause of death worldwide as well as in Peru. The national cancer plan includes decentralization, but one of the greatest barriers is our complicated geography. San Martin is a department located in the Peruvian jungle where there are no public services for cancer care. Our aim was to implement a “distance telemedicine-enabled” outpatient chemotherapy module, monitored by oncologists. Methods: The implementation was conducted in 3 stages: 1) Planning and Organization: working teams were formed, a chemotherapy room was developed and people were trained. 2) Execution: patients from San Martín region, aged >18 years with pathological confirmation of cancer, requiring systemic chemotherapy, ECOG <3, and first course of chemotherapy received at INEN without adverse reaction were selected. 3) Evaluation: adverse events, cost-user evaluation and quality of life (QoL) were assessed. Results: By November 2015, a module with a chemotherapy room with 18 chairs, a pharmacy, a hospitalization room, 1 medical office, a training room, a nutrition area, and a nursing station was implemented. 3 physicians, 3 nurses and 1 pharmacist were trained. Through March 2018, 501 sessions of teleoncology were completed to deliver 232 cycles of chemotherapy for 56 patients aged 19 - 78 years with different solid tumors, with no serious adverse event, without negatively affecting their QoL, and with an average out-of-pocket expense saving of 500 PEN. Conclusions: Using information and communication technology, a telechemotherapy module was successfully implemented in the Peruvian jungle, without adversely affecting the QoL of patients. Neither patients nor family members needed to travel to Lima to receive chemotherapy. This first program can be replicated in other rural and remote regions through non-specialized personnel and facilities, providing chemotherapy services equivalent to a tertiary center through trained health care professionals, supported through tel

关键词： Telechemotherapy Module Cancer Treatment Urban Tertiary Center Teleoncology

Molecular Modeling and Synthesis of Ethyl Benzyl Carbamates as Possible Ixodicide Activity

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Computational Chemistry 2019年第1期7卷 1-26页

作者： Vazquez-Valadez Victor Hugo Hernandez-S.Manuel Alejandro Velazquez-S.Ana Maria Rosales-H.Maria Leyva-R.Marco Antonio Prado-O.Maria Guadalupe Munoz-G.Marco Antonio Alba-H.fernando Abrego Victor Cruz-A.Diego Angeles Enrique Laboratorio de Quimica Medicinal Departamento de Ciencias QuimicasFES-Cuautitlan UNAMEdo.Mex.Mexico Laboratorio de Investigacion Nave 3000 Departamento de Ciencias QuimicasFES-Cuautitlan UNAMEdo.Mex.Mexico Departamento de Quimica CINVESTAVCd.Mx.Mexico Laboratorio 1 de la UIM Departamento de Ciencias BiologicasFES-Cuautitlan UNAMEdo.Mex.Mexico QSAR Analytics S.A.de C.V. Edo.Mex.Mexico

Carbamates are molecules that have different types of biological activities and provide a particular chemical control against ticks. The new structures of the proposed compounds were optimized and synthetized respectively, through a molecular model using the methods:PM3, HF and DFT applying the B3LYP functional, with the basis 6-31+G(d) and 6-311+G(d,p), BVP86 and PBEPBE with 6-31+G(d) and the vibrational frequencies computed. These calculated frequencies were compared with the experimental ones to determine the most accurate level of theory for the prediction of vibrational frequencies of the compounds. The best results were obtained through HF/631+G(d). Additionally, we report a modification to obtain this type of compounds, and based on the amino-dehalogenation of ethyl chloroformate, different benzyl ethyl carbamates were synthesized modifying the base molecule. The performances obtained were compared to others already reported. The methodology used allowed us to synthesize new carbamates using benzylamine derivatives through a modification on the basic catalysis of the addition-elimination reaction.

关键词： N-Carbamates Ixodicide Molecular Modeling

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粒径与晶向对纳米针铁矿体弹模量的影响

粒径与晶向对纳米针铁矿体弹模量的影响

Treatment of systemic lupus erythematosus with intravenous immunoglobulin （ivIg） and its impact on cellular subsets and immunoregulation

第十八届中国高压科学学术会议

作者：张衡中闫进元陈斌朱孟强郭华 S.fernando M.Baynes J.F.Banfield 北京高压科学研究中心美国加州大学伯克利分校美国劳伦斯伯克利国家实验室

纳米晶体的体弹模量不但是一基本力学性质,还通过纳米颗粒的表面压和表面自由能与其热力学稳定性相关联1。天然纳米针铁矿可形成于矿山酸性废水之中和和自然界磁性细菌体内,多呈现于纳米棒状。研究颗粒尺寸和形状对其体弹模量的影响有...

纳米晶体的体弹模量不但是一基本力学性质,还通过纳米颗粒的表面压和表面自由能与其热力学稳定性相关联1。天然纳米针铁矿可形成于矿山酸性废水之中和和自然界磁性细菌体内,多呈现于纳米棒状。研究颗粒尺寸和形状对其体弹模量的影响有助于探明颗粒环境(包括溶液与生物膜)对其生长、长大和热力学稳定性所起作用。本工作采用高压同步辐射X射线衍射法测定不同粒径下纳米针铁矿的状态方程及相应体弹模量;用分子动力学模拟方法得出体弹模量随纳米棒

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Treatment of systemic lupus erythematosus with intravenous i...

Diffuse intestinal ganglioneuromatosis an uncommon manifestation of Cowden syndrome

The 8th International Congress on SLE

作者： Luiz fernando Goulart Clara Pereira Ana Monica Gabriel Barbara Leal Maria Francisca Fontes Carlos Vasconcelos Carlos M.Ferreira Jorge Martins Joo Matos-Costa Berta Martins António Marinho Margarida Lima Jocelyne Demengeot Constantin Fesel Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPort

＜正＞Purpose:Intavenous immunoglobulin（ivIg）,which has well-demonstrated beneficial effects in various autoimmune diseases,is used as a therapeutic option for Systemic Lupus Erythematosus（SLE）patients,particularly for those with poor responses to standard *** studied immune homeostasis and regulation in patients undergoing this

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World Journal of Gastrointestinal Oncology 2013年第2期5卷 34-37页

作者： Maria Teresa Herranz Bachiller Jesus Barrio Andrés fernando Pons Noelia Alcaide Suárez Rafael Ruiz-Zorrilla Lorena Sancho del Val Sara Lorenzo Pelayo Carlos De La Serna Higuera Ramon Atienza Sánchez Manuel Perez Miranda Department of Gastroenterology Rio Hortega Hospital

Diffuse intestinal ganglioneuromatosis is a hamartomatous polyposis characterized by a disseminated, intramural or transmural proliferation of neural elements involving the enteric plexuses. It has been associated with MEN Ⅱ, neurofibromatosis type 1 and hamartomatous polyposis associated with phosphatase and tensin homolog mutation. We report the case of a female patient with a history of a breast and endometrial tumor who presented in a colonoscopy performed for rectal bleeding diffuse ganglioneuromatosis, which oriented the search for other characteristic findings of Cowden syndrome given the personal history of the patient. The presence of an esophagogastric polyposis was also noted. Cowden syndrome is characterized by skin lesions, but it is rarely diagnosed by these lesions, because they are usually overlooked. Intestinal polyposis is not a major diagnostic criterion but it is very useful for early diagnosis. The combination of colonic polyposis and glucogenic acanthosis should orient the diagnosis to Cowden syndrome.

关键词： Ganglioneuromatosis Gastrointestinal poliposis Phosphatase and tensin homolog Cowden síndrome Hamartoma