检索结果-南通市图书馆

On-line Tool Wear Classification in Unmanned-machining Environments

厦门大学学报（自然科学版） 2002年第S1期41卷 80-81页

作者： A D Hope G A king Systems Engineering Faculty Southampton InstituteSystems Engineering Faculty Southampton Institute Southampton UKSouthampton UK

One of the most important features of the modern ma ch ining system in an "unmanned" factory is to change tools that have been subjec ted to wear and damage. An integrated tool condition monitoring system composed of multi-sensors, signal processing devices and intelligent decision making pla ns is a necessary requirement for automatic manufacturing processes. An intellig ent tool wear monitoring system will be introduced in this paper. The system is equipped with power consumption, vibration, AE and cutting force sensors, signal transformation and collection apparatus and a microcomputer. Tool condition monitoring is a pattern recognition process in which the characte ristics of the tool to be monitored are compared with those of the standard mode ls. The tool wear classification process is composed of the following parts: fea ture extraction; determination of the fuzzy membership functions of the features ; calculation of the fuzzy similarity; learning and tool wear classification. Fe atures extracted from the time domain and frequency domain for the future patter n recognition are as follows. Power consumption signal: mean value; AE-RMS sign al: mean value, skew and kutorsis; Cutting force, AE and vibration signal: mean value, standard deviation and the mean power in 10 frequency ranges. These signa l features can reflect the tool wear states comprehensively. The fuzzy approachi ng degree and the fuzzy distance between corresponding features of different obj ects are combined to describe the closeness of two fuzzy sets more accurately. A unique fuzzy driven neural network based pattern recognition algorithm has bee n developed from this research. The combination of Artificial Neural Networks (A NNs) and fuzzy logic system integrates the strong learning and classification ab ility of the former and the superb flexibility of the latter to express the dist ribution characteristics of signal features with vague boundaries. This methodol ogy indirectly solves the auto

关键词： condition monitoring feature extraction fuzzy logic and neural networks sensor fusion pattern recognition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pharmacotherapy of anxiety disorders in the 21st century:a call for novel approaches

引用

General Psychiatry 2019年第6期32卷 304-308页

作者： Eric Bui Franklin king Andrew Melaragno Department of Psychiatry Massachusetts General HospitalBostonMassachusettsUSA Department of Psychiatry Harvard Medical SchoolBostonMassachusettsUnited States

While limited advances have occurred in the past 30 years in the pharmacological management of anxiety and stressrelated disorders,novel molecular pathways both within and without the monoamine systems are currently under investigation and offer promising new avenues for more effective future *** psychotherapy approaches with pharmacological compounds offers the potential to not only transform the standard of care of these conditions,but more broadly would introduce a paradigm shift in the way medications and their role in psychiatric care are *** further human trials and more translational research are sorely needed,continuing to pursue innovative mechanisms and treatments is hoped to yield substantial results in the coming decades and a departure from the reliance on chemical agents of the 20th century.

关键词： departure anxiety innovative

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of driving conditions and suspension parameters on dynamic load-sharing of longitudinal-connected air suspensions

引用

Science China Technological Sciences 2013年第3期56卷 666-676页

作者： CHEN YiKai HE Jie king Mark CHEN WuWei ZHANG WeiHua School of Transportation Engineering Hefei University of Technology Traffic Management Research Institute of the Ministry of Public Security School of Transportation Southeast University Centre for Accident Research and Road Safety-Queensland Queensland University of TechnologyKelvin Grove 4059Australia School of Mechanical and Automotive Engineering Hefei University of Technology

The objective of this research was to investigate the effects of driving conditions and suspension parameters on dynamic load-sharing of longitudinal-connected air suspensions of a tri-axle semi-trailer.A novel nonlinear model of a multi-axle semi-trailer with longitudinal-connected air suspension was formulated based on fluid mechanics and thermodynamics and was validated through test *** effects of driving conditions and suspension parameters on dynamic load-sharing and road-friendliness of the semi-trailer were *** results indicate that the road-friendliness metric-DLC(dynamic load coefficient) is not always in accordance with the load-sharing metric-DLSC(dynamic load-sharing coefficient).The effect of employing larger air lines and connectors on the DLSC optimization ratio gives varying results as road roughness increases and as driving speed *** the vehicle load reduces,or the static pressure increases,the DLSC optimization ratio declines *** results also indicate that if the air line diameter is always assumed to be larger than the connector diameter,the influence of air line diameter on load-sharing is more significant than that of the connector.

关键词： driving condition dynamic load-sharing longitudinal-connected air suspension heavy truck

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Preparation and Mechanical Performance of Blended Polyester/Silk Small Diameter Arterial Prostheses

引用

Journal of Donghua University(English Edition) 2013年第5期30卷 356-358页

作者：杨小元王璐关国平关颖 king W Martin Key Laboratory of Textile Science and Technology Ministry of EducationDonghua University College of Textiles Donghua University College of Textiles North Carolina State University

Small diameter arterial prostheses were required to treat coronary and cerebrovascular arterial diseases. The diameters of the artificial blood vessels should match the diameters of the host arteries. Besides,the mechanical properties of the arterial prostheses should be strong enough to endure the forces in the body after implantation. In this study,silk and polyester were woven into small diameter arterial prostheses and the dimensional and mechanical properties,as well as the water permeability,were investigated. The woven samples had an inner diameter ranging from 3. 65 to 3. 94mm. The wall thickness of the samples ranged from 0. 26 to 0. 28mm. Compared with polytetrafiuoroethylene( ePTFE) commercial devices,whose probe bursting strength was measured to be 15. 64 N /mm2,the woven samples had superior strength values ranging from20. 53 to 28. 97 N /mm2. In addition,the radial compliance of the woven samples was found to lie between the ePTFE sample and the pig's carotid artery,and the water permeability of all the woven samples was less than 300 mL /( cm2·min) which indicated that these woven samples could be implanted without preclotting.

关键词： silk polyester woven arterial prostheses mechanical properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel Function of TNF Cytokines in Regulating Bone Marrow B Cell Survival

引用

Cellular & Molecular Immunology 2004年第6期1卷 447-453页

作者： MinZhang king-HungKo QueenieLaiKwanLam CherryKamChunLo DanielJiaLinXu LijunShen BojianZheng GopeshSrivastava LiweiLu DepartmentsofPathologytheUniversityofHongKong HongKongChina. DepartmentsofMicrobiologytheUniversityofHongKong HongKongChina. DepartmentsofPathologytheUniversityofHongKong HongKongChina. ／／Correspondingto：Dr.LiweiLuImmunologyDivision.DepartlnentofPathologytheUniversityofHongKongPokfulamRoad.HongKongChina.

Two newly identified tumor necrosis factor (TNF) family cytokines,B cell activation factor from the TNF family (BAFF) and a proliferation-inducing ligand (APRIL),have recently been shown to enhance the maturation and survival of peripheral B ***,whether BAFF and APRIL are expressed in the bone marrow (BM) microenvironment and if these two cytokines modulate early B cell development remain unclear. In the present study,we have detected the abundant expression of BAFF and APRIL transcripts in BM non-lymphoid *** levels of BAFF and APRIL mRNA are also found in developing B ***, we have determined the expression patterns of BAFF receptors during B *** cultures,both recombinant BAFF and APRIL significantly promote the survival of precursor B cells whereas only BAFF can suppress apoptosis of immature B *** findings suggest that BAFF and APRIL,in addition to their well established role in regulating peripheral B cell growth,can modulate the survival of developing B cells in the *** & Molecular Immunology.2004;1(6):447-453.

关键词： B cell apoptosis cytokine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intestine-derived α-synuclein initiates and aggravates pathogenesis of Parkinson’s disease in Drosophila

引用

Translational Neurodegeneration 2022年第1期11卷 262-279页

作者： Wei Liu Kah-Leong Lim Eng-king Tan School of Plant Protection Anhui Province Key Laboratory of Crop Integrated Pest ManagementAnhui Province Engineering Laboratory for Green Pesticide Development and ApplicationAnhui Agricultural UniversityHefei 230036China Department of Neurology National Neuroscience InstituteSingapore 308433Singapore Department of Research National Neuroscience InstituteSingaporeSingapore Research Lee Kong Chian School of Medi-cineSingaporeSingapore Neuroscience and Behavioural Disorders Program Duke-NUS Medical SchoolSingapore 169857Singapore.

Background:Aberrant aggregation ofα-synuclein(α-syn)is a key pathological feature of Parkinson’s disease(PD),but the precise role of intestinalα-syn in the progression of PD is *** a number of genetic Drosophila models of PD,α-syn was frequently ectopically expressed in the neural system to investigate the ***:We investigated the potential role of intestinalα-syn in PD pathogenesis using a Drosophila ***α-syn was overexpressed in Drosophila guts,and life span,survival,immunofluorescence and climbing were ***,Western blotting and reactive oxygen species(ROS)staining were performed to assess the effects of intestinalα-syn on intestinal ***‐throughput RNA and 16S rRNA gene sequencing,quantitative RT‐PCR,immunofluorescence,and ROS staining were performed to determine the underlying molecular ***:We found that the intestinalα-syn alone recapitulated many phenotypic and pathological features of PD,including impaired life span,loss of dopaminergic neurons,and progressive motor *** intestine-derivedα-syn disrupted intestinal homeostasis and accelerated the onset of intestinal ***,intestinal expression ofα-syn induced dysbiosis,while microbiome depletion was efficient to restore intestinal homeostasis and ameliorate the progression of ***α-syn triggered ROS,and eventually led to the activation of the dual oxidase(DUOX)-ROS-Jun N-terminal Kinase(JNK)*** addition,α-syn from both the gut and the brain synergized to accelerate the progression of ***:The intestinal expression ofα-syn recapitulates many phenotypic and pathologic features of PD,and induces dysbiosis that aggravates the pathology through the DUOX-ROS-JNK pathway in *** findings provide new insights into the role of intestinalα-syn in PD pathophysiology.

关键词： Intestine α-Synuclein Parkinson’s disease Microbiome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sleeping beauties

Sleeping beauties

引用

作者： Stephen king and Owen king.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Microfabrication of Bubbular Cavities in PDMS for Cell Sorting and Microcell Culture Applications

引用

Journal of Bionic Engineering 2008年第4期5卷 308-316页

作者： Ut-Binh T. Giang Michael R. king Lisa A. DeLouise Department of Biomedical Engineering University of Rochester Department of Biomedical Engineering Cornell University Department of Dermatology University of Rochester Medical Center

We describe a novel technique, low surface energy Gas Expansion Molding （GEM）, to fabricate microbubble arrays in polydimethylsiloxane （PDMS） which are incorporated into parallel plate flow chambers and tested in cell sorting and microcell cuTture applications. This architecture confers several operational advantages that distinguish this technology approach from currently used methods. Herein we describe the GEM process and the parameters that are used to control microbubble formation and a Vacuum-Assisted Coating （VAC） process developed to selectively and spatially alter the PDMS surface chemistry in the wells and on the microchannel surface. We describe results from microflow image visualization studies conducted to investigate fluid streams above and within microbubble wells and conclude with a discussion of cell culture studies in PDMS.

关键词： polydimethylsiloxane microfabrication cell culture cell sorting molding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Alternative Derivation of the Propagator in Polar Coordinates by Feynman's Physical Interpretation of the Characteristic Function

引用

Communications in Theoretical Physics 2002年第5期38卷 529-532页

作者： QIAN Shang-Wu CHAN king-Man GU Zhi-Yu Physics Department Peking University Beijing 100871 China Physics Department Peking University Beijing 100871 China Physics Department Capital Normal University Beijing 100037 China

This article revisits Feynman's characteristic function, and points out the insight and usefulness of hisphysical interpretation. As an example, the tedious and rather long derivation of the propagator in polar coordinatescan be easily and clearly obtained by merely using Feynman's physical intepretation of the characteristic function andsome well-known results of central force problem.

关键词： Feynman's characteristic function, propagator in polar coordinates

来源：

维普期刊数据库

维普期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The potential function of post-fledging dispersal behavior in first breeding territory selection for males of a migratory bird

引用

Current Zoology 2022年第6期68卷 708-715页

作者： Robert PATCHETT Patrick STYLES Joanna ROBINS king Alexander NGKIRSCHEL Will CRESSWELL Centre for Biological Diversity University of St AndrewsSt AndrewsKY169THUK Department of Biological Sciences University of CyprusNicosia1678Cyprus

One possible hypothesis for the function of post-fledging dispersal is to locate a suitable future breeding *** post-fledging period may be particularly important in migratory species because they have a limited period to gather information prior to autumn migration,and in protandrous species,males must quickly acquire a territory after returning from spring migration to maximize their *** we use color-ring resightings to investigate how the post-fledging dispersal movements of the Cyprus wheatear Oenanthe cypriaca,a small migratory passerine,relate to their first breeding territory the following year when they return from *** found that males established first breeding territories that were significantly closer to their post-fledging location than to their natal sites or to post-fledging locations of other conspecifics,but these patterns were not apparent in *** findings suggest that familiarity with potential breeding sites may be important for juveniles of migratory species,particularly for the sex that acquires and advertises breeding *** dispersal prior to a migrant’s first autumn migration may contribute toward its breeding success the following year,further highlighting the importance of early seasonal breeding on fitness and population dynamics more generally.

关键词： dispersal migratory bird juvenile territory selection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：