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Timing of pubertal development in boys born with cryptorchidism and hypospadias:a nation wide cohort study

作者： ernst Rebel Norbert Wolf (ed.)

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Asian Journal of Andrology 2019年第6期21卷 551-556页

作者： Linn Hakonsen Arendt Andreas ernst Lea Lykke Braskhoj Lauridsen Nis Brix Jorn Olsen Cecilia Host Ramlau-Hansen Department of Public Health Section for EpidemiologyAarhus UniversityAarhus 8000Denmark Perinatal Epidemiology Research Unit Department of Paediatric and Adolesce nt Medici neAarhus Un iversity HospitalAarhus 8000Den mark Department of Clin ical Epidemiology Aarhus University HospitalAarhus 8000Denmark.

Pubertal development may be altered in boys with cryptorchidism and hypospadias,but existing kno wledge is inc on siste ***,we investigated the association between cryptorchidism and hypospadias and pubertal development in a large cohort *** in the Puberty Cohort,a cohort nested within the Danish National Birth Cohort,were in eluded in this *** on cryptorchidism and hypospadias was retrieved from the Danish National Patient *** 11 years until 18 years or full pubertal developme nt,info rmatio n on physical markers of pubertal developme nt was provided biannu ally,in eluding Tanner stages,axillary hair,acne,voice break,and first *** multivariate regression models for interval censored data,the mean(95%confidence intervals[Cis])d iff ere nces in months in obtaining the pubertal markers between boys with and without the anomalies were *** 7698 boys,196(2.5%)had cryptorchidism and 60(0.8%)had *** with hypospadias experienced first ejaculation and voice break 7.7(95%Cl:2.5-13.0)months and 4.5(95%Cl:0.3-8.7)months later than boys without hypospadias?The age at attaining the Tanner stages for gonadal and pubic hair growth was also higher,though not statistically *** development seemed unaffected in boys with mild as well as severe cryptorchidism?In conclusion,hypospadias may be associated with delayed pubertal development,but pubertal development seems unaffected by *** relation between hypospadias and later pubertal development may be due to the underlying shared in utero risk or genetic factors.

关键词： congenital abnormalities cryptorchidism hypospadias prenatal exposure delayed effects puberty Tanner stages

Drought sensitivity of beech on a shallow chalk soil in northeastern Germany - a comparative study

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Forest Ecosystems 2017年第1期4卷 45-54页

作者： Marieke van der Maaten-Theunissen Hanna Bummerstede Janette Iwanowski Tobias Scharnweber Martin Wilmking ernst van der Maaten Institute of Botany and Landscape Ecology University of Greifswald Soldmannstr 15 17487 Greifswald Germany

Background： We compare the climate sensitivity of European beech （Fagus sylvatica L.） in two forest nature reserves in northeastern Germany. The one reserve, Schlossberg, is characterized by shallow chalk soils, whereas in the other reserve, EIdena, soils are deeper and more developed. Little is known about the drought sensitivity of beech on shallow chalk soils. Methods： We collected increment cores at both research sites and established climate-growth relationships. Inter- tree variability was assessed by employing linear mixed-effect models. Results： We expected to find distinctively higher drought sensitivity at Schlossberg due to limited water availability, but find only marginal differences in growth responses. At both sites, drought is the major climatic factor driving tree growth. Adaptations in tree architecture and an underestimation of the water holding capacity of shallow chalk soils are discussed as possible reasons for not finding more distinct climate responses. In analyzing climate-growth relationships, we specifically focused on growth responses of individual trees but observed only low inter-tree variability at both sites. Evident is a shift in climate response patterns from the first to the second half of the twentieth century with previous-year drought conditions becoming more important than current-year drought. This shift is discussed in relation to a warming trend over that same period, as well as possible trends in masting behavior of beech. Conclusion： The investigated beech trees on the shallow chalk soil are only slightly more drought sensitive than beech trees on the reference site with deeper and more developed soils.

关键词： Climate-growth relationships Dendroecology Inter-tree variability Temporal stability Drought stress

The Common Topological Origin of Waves in Quantum and Photon Physics as Well as in the Cosmic Redshift

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Natural Science 2022年第2期14卷 94-116页

作者： ernst Karl Kunst Im Spicher Garten 5 53639 K&ouml nigswinter Germany

It is shown that the well-known wave behaviors of material particles and photons, as well as the newly discovered wave-like structures in the cosmic redshift, are related phenomena that follow conclusively when senders and receivers of photons or material particles are topologically located in manifolds with a dimension difference of one. In this context, the inertial mass of the proton and the electron, their spin properties and the cause of time are derived from basic topological and physical laws. In addition, the quantum geometric basis of relativistic time dilation, the basis of the relativistic energy-momentum relationship and the relationship between energy and time are shown. Finally, it is shown that a curved cosmic space causes a distance-dependent reddening of light and the associated apparent escape velocity of distant cosmic objects, and that this also leads to a topologically conditioned wave structure of this redshift.

关键词： Waves in Particle and Photon Physics Cosmic-Redshift Wavelike Pattern Topological Interpretation Cause of Mass and Time

Why Explore Space(Extract)

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英语学习 2022年第5期 62-65+72页

作者： ernst Stuhlinger

学习任务Activity 1 Think about the following questions, and write down your answers before reading the essay.(1) Have you ever done something without success, but gained something else unexpectedly?(2) What benefits d...

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Relativistic Quantitative Determination of the “Mysterious” Differences in the Hubble Constant

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Natural Science 2021年第1期13卷 1-7页

作者： ernst Karl Kunst Kö nigswinter Germany

This paper discusses the “Hubble constant measurement—mystery”. Independent measurements of this cosmic parameter, referred to as H0 in abbreviated form, have all led to different values, with the highest value ≈ 74 km·s-1·Mpc-1 and the lowest ≈ 67 km·s-1·Mpc-1, where km denotes kilometer, s second and Mpc-1 megaparsec. These measurements have mainly been obtained with space telescopes. Apparently, up to now there was no way to explain the differences. However, previously published studies seem to regard the problem of the different measurement results for H0 [1, 2]. I have shown that due to a symmetrical

关键词： Hubble Constant Different Measurement Results Earthbound and Space-Telescopes Different Orbits Different Hubble Constants Symmetric Special Relativistic Origin

Management of acute nonvariceal upper gastrointestinal bleeding:Current policies and future perspectives

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World Journal of Gastroenterology 2012年第11期18卷 1202-1207页

作者： Ingrid Lisanne Holster ernst Johan Kuipers Department of Gastroenterology and Hepatology Erasmus MC University Medical Centre Departments of Gastroenterology and Hepatology and Internal MedicineErasmus MC University Medical Centre

Acute upper gastrointestinal bleeding(UGIB) is a gastroenterological emergency with a mortality of 6%-13%.The vast majority of these bleeds are due to peptic *** anti-inflammatory drugs and Helicobacter pylori are the main risk factors for peptic ulcer *** has become the mainstay for diagnosis and treatment of acute UGIB,and is recommended within 24 h of *** pump inhibitor(PPI) administration before endoscopy can downstage the bleeding lesion and reduce the need for endoscopic therapy,but has no effect on rebleeding,mortality and need for *** therapy should be undertaken for ulcers with high-risk stigmata,to reduce the risk of *** can be done with a variety of ***-dose PPI administration after endoscopy can prevent rebleeding and reduce the need for further intervention and mortality,particularly in patients with high-risk stigmata.

关键词： Disease management Upper gastrointesti-nal bleeding Nonvariceal bleeding Peptic ulcer bleed-ing Gastrointestinal endoscopy Pharmacotherapy Endoscopic therapy

Investigation of Li-ion transport in Li7P3S11 and solid-state lithium batteries

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Journal of Energy Chemistry 2019年第11期28卷 1-7页

作者： Chuang Yu Swapna Ganapathy ernst R.H.van Eck Lambert van Eijck Niek de Klerk Erik M.Kelder Marnix Wagemaker Department of Radiation Science and Technology Delft University of TechnologyMekelweg 152629JB Delftthe Netherlands Institute for Molecules and Materials Radboud University NijmegenHeyendaalseweg 1356525 AJ Nijmegenthe Netherlands

The high Li-ion conductivity of the Li7P3S11 sulfide-based solid electrolyte makes it a promising candidate for all-solid-state lithium batteries. The Li-ion transport over electrode-electrolyte and electrolyteelectrolyte interfaces, vital for the performance of solid-state batteries, is investigated by impedance spectroscopy and solid-state NMR experiments. An all-solid-state Li-ion battery is assembled with the Li7P3S11 electrolyte, nano-Li2S cathode and Li-In foil anode, showing a relatively large initial discharge capacity of 1139.5 m Ah/g at a current density of 0.064 m A/cm^ 2 retaining 850.0 m Ah/g after 30 cycles. Electrochemical impedance spectroscopy suggests that the decrease in capacity over cycling is due to the increased interfacial resistance between the electrode and the electrolyte. 1D exchange ^7Li NMR quantifies the interfacial Li-ion transport between the uncycled electrode and the electrolyte, resulting in a diffusion coefficient of 1.70(3) ×10^-14cm^2/s at 333 K and an energy barrier of 0.132 e V for the Li-ion transport between Li2S cathode and Li7P3S11 electrolyte. This indicates that the barrier for Li-ion transport over the electrode-electrolyte interface is small. However, the small diffusion coefficient for Li-ion diffusion between the Li2S and the Li7P3S11 suggests that these contact interfaces between electrode and electrolyte are relatively scarce, challenging the performance of these solid-state batteries.

关键词： Li7P3S11 Li-ion transport Spin-lattice NMR Exchange NMR Solid-state battery

SIMULATION OF PARTICLE COATING IN THE SUPERCRITICAL FLUIDIZED BED

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China Particuology 2005年第1期3卷 113-124页

作者： Carsten Vogt ernst-Ulrich Hartge Joachim Werther Gerd Brunner Technical University Hamburg-Harburg D21071 Hamburg Germany

Fluidized bed technology using supercritical carbon dioxide both as a fluidizing gas and as a solvent for the coating material makes possible the production of thin, uniform and solvent-free coatings. But operation at low fluidizing velocities, which is favorable to facilitate gas cleaning under the high pressure conditions, may lead to uneven distribution of the coating in the fluidized bed and to unstable operation due to agglomeration. Therefore a model has been developed which describes local fluid dynamics within the high pressure fluidized bed. Based on this model, the coating process is described and the distribution of the coating inside the fluidized bed is calculated. Furthermore a submodel for the calculation of local concentrations of liquid paraffin has been set up, which may be used as a basis for the prediction of agglomeration and thus stability of operation.

关键词： particle coating fluidized bed supercritical fluid fluid mechanics