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Modern research in Inflammation 2014年第2期3卷 27-36页

作者： Glenda ernst Jancic Carolina Auteri Santiago rodriguez Moncalvo Juan Galíndez Fernando Grynblat Pedro e. Hajos Silvia Faculty of Pharmacy and Biochemistry Immunology IDEHU UBA-CONICET Buenos Aires Argentina National Academy of Medicine IMEX-CONICET Buenos Aires Argentina respiratory rehabilitation Hospital María Ferrer Buenos Aires Argentina

Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It described the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contributes to the recruitment of inflammatory cells associated with ILD. If this hypothesis was correct, then concentrations of HA in bronchoalveolar lavage (BAL) should correlate with the severity of ILD. Methods: We collected BAL from 22 ILD patients and 15 control subjects. We determined HA and cytokine levels by eLISA. In vitro chemotaxis assays were performed by using a transwell system. results: We found that ILD patients showed a significant increase in HA, IL-6 levels and the amount of cells in BAL compared to control subjects. We detected a significant positive correlation between HA and IL-6 levels (r = 0.53 and p In vitro, HA induced migration of macrophages and monocytes through a CD44-dependent process. BAL from patients with ILD stimulated macro-phage migration and this was abrogated by hyaluronidase. Conclusions: Our results support the hypothesis that HA contributes to the recruitment of monocytes towards the alveolar space, leading to exacerbation of lung inflammation in ILD patients.

关键词： Hyaluronic Acid Interstitial Lung Diseases Lung Inflammation

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论道德的概念与论证

南京大学学报（哲学．人文科学．社会科学） 2007年第3期44卷 104-112页

作者： e.图根特哈特辛启义图宾根大学哲学系德国图宾根d72074

启蒙以来的现代境况使得道德及其论证的问题既重要又困难。一方面,传统论道德连同其更高真理包含着无法论证的前提,因而所有道德的核心必须还原到规范之自然的或合理的基本存在之上;另一方面,契约论以及其他现代道德替代品涉及的仅仅是... 详细信息

启蒙以来的现代境况使得道德及其论证的问题既重要又困难。一方面,传统论道德连同其更高真理包含着无法论证的前提,因而所有道德的核心必须还原到规范之自然的或合理的基本存在之上;另一方面,契约论以及其他现代道德替代品涉及的仅仅是一种外部的社会裁定,而道德则是一种在羞愧、义愤等道德感受中感受到的内部的社会裁定。因此,道德的可能性只在于:本质上将自身理解为一个共同体一般以及与此相关的受到普遍尊重之观念的环节。

关键词：道德内部裁定共同体羞愧普遍尊重

放射性废物管理的安全标准:将国际共识形成文件

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国际原子能机构通报 1994年第2期36卷 17-21页

作者： ernst Warnecke Donald e.Saire IAeA核燃料循环与废物管理处废物管理科

放射性废物来自核能生产和放射性材料在工业、研究、医学等领域的应用。其安全管理对于保护人的健康和环境的重要性早已被人们所认识,而且取得了大量经验。过去几年中,国际原子能机构(IAeA)

关键词：放射性废物管理安全标准

用皮尔斯图解模拟火成岩的分异作用及其它过程

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地质科学译丛 1989年第4期6卷 7-13页

作者： richard e.ernst 许继锋

借助皮尔斯(Pearce)图解,能对地球化学数据作定量模拟.这种图以A/Z与B/Z为坐标,其中A、B、Z均是成分的含量(例如WSiO_2％,W MgO％或La ppm),Z还具有另外一个性质,就是它的绝对含量不变。在火成岩石学术语中,Z(公分母变量)是一个不相容... 详细信息

借助皮尔斯(Pearce)图解,能对地球化学数据作定量模拟.这种图以A/Z与B/Z为坐标,其中A、B、Z均是成分的含量(例如WSiO_2％,W MgO％或La ppm),Z还具有另外一个性质,就是它的绝对含量不变。在火成岩石学术语中,Z(公分母变量)是一个不相容元素。分子项(A或B)可以是几种元素的数学复合项,甚至还可以是CIPW标准矿物的含量。皮尔斯图的应用依据以下事实:一套同源岩石数据分布所成直线的斜率,等于这套岩石减少或增加的矿物中元素A:B的总比率.由于已对这些数据的投影点作了拟合,因而没有投影偏差。用A_i·Z_o/Z_i(Z_o是参考样品中的含量)这样的式子避免了由于选择特定Z值而带来的换算Ai值的麻烦.对于不同样品,上述式子的差值[例如A_i·(Z_o/Z_i)-A·(Z_o/Z_i)],可以确定矿物减少或者增加的数量。数学分析表明:分母这个变量具有限的相容元素特征是允许的。当总分配系数(D)为0.1分异超过50％时,A_i·Z_o/Z_i值的误差仅占10％,皮尔斯图上的直线斜率的角偏差也仅为10°。当D≤0.01、分异超过90％时,引起的误差可忽略不计。

关键词：皮尔斯图解火成岩分异作用

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多变鱼腥藻半稳定状态连续培养的若干特征

水生生物学报 1992年第3期16卷 224-229页

作者：刘永定黎尚豪 ernst A Bger P 中国科学院水生生物研究所武汉430072 德意志联邦共和国Konstanz大学

分别使用恒化装置和全玻璃发酵罐连续培养多变鱼腥藻。在稳定条件下加以周期性的光照(L∶D=12∶12),经5—6d得到半稳定状态连续培养物。在光照阶段,培养物的生物量增长速度约等于稀释速度D的两倍,叶绿素的增长速度略小于D的两倍,糖原的... 详细信息

分别使用恒化装置和全玻璃发酵罐连续培养多变鱼腥藻。在稳定条件下加以周期性的光照(L∶D=12∶12),经5—6d得到半稳定状态连续培养物。在光照阶段,培养物的生物量增长速度约等于稀释速度D的两倍,叶绿素的增长速度略小于D的两倍,糖原的累积速度几乎高出D^5的一个数量级。细胞内糖原和蛋白质含量变化的时间过程反映出培养物在光-暗条件下的碳氮物质合成与消耗相互联系的代谢特点。半稳定状态连续培养受培养物内在的生理活性支配,生长参数的变化符合方程X=X_(oe)^((μ-D)~t),但不同于恒浊培养和恒化培养。外界因素的强弱变化只改变生长参量变化的强度。本法适用于研究微藻的生态生理。

关键词：连续培养多变鱼腥藻生态生理

Biodiversity and belowground interactions mediate community invasion resistance against a tall herb invader

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Journal of Plant ecology 2010年第2期3卷 99-108页

作者： Christoph Scherber Peter NMwangi Martin Schmitz Michael Scherer-Lorenzen Holger Beßler Christof engels Nico eisenhauer Varvara DMigunova Stefan Scheu Wolfgang WWeisser ernst-Detlef Schulze Bernhard Schmid Agroecology Department of Crop ScienceUniversity of GottingenWaldweg 26D-37073 GottingenGermany Institute of evolutionary Biology and environmental Studies University of ZurichWinterthurerstraße 92CH-8057 ZurichSwitzerland Max Planck Institute for Biogeochemistry Hans-Knoll Straße 10D-07745 JenaGermany Institute of ecology Jena UniversityDornburger Straße 159D-07743 JenaGermany Institut fur Biologie II/Geobotanik Schanzlestr.1D-79104 FreiburgGermany Humboldt Universitat zu Berlin Fachgebiet PflanzenernahrungAlbrecht-Thaer-Weg 4D-14195 BerlinGermany J.F.Blumenbach Institute of Zoology and Anthropology University of GottingenBerliner Str.28D-37073 GottingenGermany K.I.Skryabin All-russian Institute of Helminthology Bolschaya Tcheryomuschkinskaya str.28117218 MoscowRussia

Aims Species-rich plant communities are hypothesized to be more resistant against plant invasions because they use resources in a more efficient ***,the relative contributions of aboveground competition and belowground interactions for invasion resistance are still poorly *** We compared the performance of Knautia arvensis transplants growing in plots differing in plant diversity both under full competition and with shoots of neighbors tied back to determine the relative strength of aboveground competition in suppressing this test invader without the confounding effect of *** addition,we assessed the effects of belowground competition and soil-borne pathogens on transplant *** Findings Both aboveground competition and plant species richness strongly and independently affected invader *** biomass,height,leaf mass per area and flowering of transplanted individuals of *** decreased with increasing species richness of the host ***-rich and species-poor communities both imposed equally strong aboveground competition on ***,belowground interactions(especially belowground root competition)had strong negative effects on transplant *** addition,the presence of grasses in a plant community further reduced the performance of *** results suggest that belowground competition can render species-rich host communities more suppressive to newly arriving species,thus enhancing community invasion resistance.

关键词： aboveground competition competitive suppression belowground interactions root competition shoot exclusion species richness

Studying Tuff rings and Volcanic Hazards in a Tropical Setting: The Case of the Batoke Tuff ring, Limbe, SW region Cameroon

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Open Journal of Geology 2023年第8期13卷 883-899页

作者： George Teke Mafany edison Forbuck Njei Gerald G. J. ernst Wilson Yetoh Fantong Cheo emmanue Suh Samuel Ndonwi Ayonghe robert Stephen John Sparks Koffi Teke Mafany Stephen Manga Njome Institute of Geological and Mining research Yaoundé Cameroon Department of Geology University of Buea Buea Cameroon Department of Geology University of Bamenda Bamenda Cameroon Department of Geology and Soil Science University of Ghent Ghent Belgium Department of earth Sciences University of Bristol Bristol UK Department of earth & Space/Physics Cypress Springs High School Houston USA

In subtropical volcanic environments, there are often few accessible outcrops. These are often highly weathered and of very poor quality. Soil development is rapid (1 cm/y) and small eruptions are unlikely to be preserved in the geological record. reconstructing past eruptions and assessing hazards is a challenge. Here, we studied a poorly outcropping tuff ring (very poor, incomplete sections) with the best outcrop observed at a beach cliff (up to ca. 5 - 10 m high) at Batoke, to the south of Mt Cameroon volcano. Mt Cameroon has a few tuff rings, currently of unknown ages, near the SW coast of Cameroon. In the Batoke case, the sequence is dominated by gently dipping tuff beds varying in the proportion of lithics, juvenile clasts, and accretionary lapilli (acc-laps). Several beds are close-packed with acc-laps of up to 10 - 15 mm diameter. Part of the section is gullied by mud flow deposits. The rocks are highly weathered but differential weathering enhances relationships. Quantitative data can be extracted from a detailed study of outcrops’ external surfaces. The preserved section is close to where the deposits were initially thickest and where acc-laps were most abundant and largest. There is an empirical correlation between maximum acc-lap size in the thickest outcrop and eruption column height. This and the deposit features suggest that the Batoke eruption was pulsating but dominated by fallout, with a water and ice-rich eruption column reaching 10 - 15 km high. recycling of water drops and ice-coated fine ash accumulated during eruption. At switch off, wholesale gravitational collapse of this material produced the mud flows, which gullied the previously-laid down deposits. Such ash fall and mud flows can represent a substantial hazard, e.g. they can gully down through towns and roads and cut evacuation routes. This study illustrates how, at subtropical tuff rings, it is possible to extract key data needed for hazard assessment from only 1 - 2 poor outcrops.

关键词： Batoke Tuff ring (BTr) Accretionary Lapilli

establishing a breast cancer center in Herat,Afghanistan:an implementation study

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Global Health Journal 2021年第4期5卷 204-208页

作者： Aziz-ur-rahman Niazi Aziz Ahmad Jami Ahmad Zia Shams Ahmad Saeed Mahmoodi eckart Krapfl Stephan Falk Alexander Buia ernst Hanisch Faculty of Medicine Herat UniversityHeratAfghanistan Afghanistan Surgeons Society-West Andisha buidingEast of Herat Stadium7 Ahmad Shah Bada RoadHeratAfghanistan Kimia Hospital Qomandani Amniya StreetHeratAfghanistan German Cancer research Center Im Neuenheimer Feld 280Heidelberg 69120Germany Interdisziplinäres Brustzentrum Asklepios Klinik LangenRöntgenstraβe 20Langen 63225Germany Center for Histology Cytology and Molecular Diagnostics TrierMax-Planck-Str.5Trier 54296Germany Department of General Visceral and Thoracic Surgery Asklepios Klinik LangenRöntgenstraβe 20Langen 63225Germany

Objective:Breast cancer is the most common cancer in women,causing significant mortality in the world,which contributed 11.7%to the overall cancer-related mortality in *** 2018,3062 new breast cancer cases were reported accounting for 29.7%of all cancers in women in the ***,a comprehensive diagnostic and therapeutic system is lacking in *** this paper,we reported the implementation of a project aiming to establish a comprehensive breast cancer center in Herat province of ***:From July 2017,a two-year-program initiated at Kimia Hospital in *** first free diagnostic and therapeutic breast cancer project planned by the Afghanistan Surgeons Society-West and the Verein für Afghanistan-Förderung e.V.,as well supported by three international *** target populations of this project were women presenting with breast problems at Kimia Hospital in Herat and healthcare staff involved in breast cancer diagnosis and ***:A group of six medical personnel chosen to represent the breast cancer core team for breast cancer diagnosis and management were trained in *** caregivers established the breast cancer service and tumor *** a period of 20 months,a total of 632 women with breast problems presented to Kimia Hospital of whom 44(7.0%)were diagnosed with breast *** was established by a physical examination,ultrasonography,mammography,biopsy and *** included surgery,radiotherapy and *** seminars for 512 healthcare workers,1000 brochures and a movie were prepared for awareness-raising *** continuation of this project,potential resource providers were identified.A database was developed to record project ***:Implementation of this comprehensive breast cancer project resulted in significant achievements in healthcare staff capacity building,diagnosis and management of breast cancer patients in Herat *** obtai

关键词： Breast cancer Implementation Heart Afghanistan

Age and Geochemical Characteristics of Major Mafic Dyke Swarms in the Southern Part of the Siberian Craton

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Acta Geologica Sinica(english edition) 2016年第S1期90卷 125-126页

作者： Tatiana V.DONSKAYA Dmitry P.GLADKOCHUB richard e.ernst Sergei A.PISAreVSKY Anatoliy M.MAZUKABZOV Ulf SODerLUND Michael T.D.WINGATe Michael A.HAMILTON elena I.DeMONTerOVA Institute of the earth’s Crust Siberian Branch of the Russian Academy of Sciences Department of earth Sciences Carleton University Faculty of Geology and Geography Tomsk State University Australian research Council Centre of excellence for Core to Crust Fluid Systems(CCFS)and the Institute for Geoscience research(TIGe r) Department of Applied GeologyCurtin University School of earth and environment University of Western Australia GeoB iosphere Science Centre Department of GeologyUniversity of Lund Geological Survey of Western Australia Department of earth Sciences University of Toronto

Several generations of mafic dyke swarms of different ages and geochemical characteristics cut Precambrian rocks of the southern part of the Siberian craton(Irkutsk Promontory).each generation of dykes is related to a

关键词： Age and Geochemical Characteristics of Major Mafic Dyke Swarms in the Southern Part of the Siberian Craton ppm

高性能分步重复对准系统的性能数据及混合匹配

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电子工业专用设备 1985年第3期 95-104页

作者： Herbert e. Mayer ernst W. Loebach 张晓

本文简要地介绍了1980年问世的晶片分步重复对准系统,接着着重讨论了全晶片对准设备的混合匹配,详细论述了与混合匹配有关的问题(晶片预对准和曝光区的精对准)。给出了分辩率、套刻精度、生产率的基本性能数据,并报道了首次混合匹配的... 详细信息

本文简要地介绍了1980年问世的晶片分步重复对准系统,接着着重讨论了全晶片对准设备的混合匹配,详细论述了与混合匹配有关的问题(晶片预对准和曝光区的精对准)。给出了分辩率、套刻精度、生产率的基本性能数据,并报道了首次混合匹配的结果。

关键词：掩模对准台晶片对准系统套刻畸变误差性能数据全视场微米级光学头