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Electrospinning Polylactic Acid Polymer Membranes as Biological Sieve for Yeast and Bacteria

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Materials Sciences and Applications 2022年第6期13卷 389-400页

作者： ernesto suaste-gómez grissel Rodríguez-Roldán Ilian Pérez-Solis Ana Laura Torres-Huerta Carlos Cruz-Cruz José Tapia-Ramírez Department of Electrical Engineering Section of Bioelectronics Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV) Mexico City Mexico National Laboratory of Experimental Services (LaNSE) CINVESTAV Mexico City Mexico Department of genetics and Molecular Biology CINVESTAV Mexico City Mexico

Vaginal infections are suffered by millions of women of reproductive age. Recent research has shown that timely diagnosis of these infections avoids complications in the patient’s health. Since the symptoms of infections caused by yeast and bacteria are similar, the patient is not always treated properly. Membranes with three different thicknesses (66 μm, 83 μm, 128 μm) were produced by electrospinning of polylactic polymer (PLA) and were used as a biological sieve to detect microorganisms present in vaginal infections, bacteria or yeasts. Electrospinning technique is a technique that allows the generation of membranes from nanofibers of material polymeric and therefore, obtaining porous structures. The size of the fibers was observed as well as the morphology and the size of the pores, using the scanning electron microscopy (SEM). The effectiveness of these membranes was proven by the cultivation of the bacteria that passed through the polymeric membrane and the yeasts retained by it. The membranes allowed the retention of yeasts of Candida albicans type with dimensions of 7 μm, which allowed the separation of Brevibacterium ravens purgense bacteria with dimensions of 1.4 μm, thus demonstrating their effectiveness as biological sieve.

关键词： Biological Sieve Electrospinning Polylactic Acid Vaginal Infections

From single to combinatorial therapies in spinal cord injuries for structural and functional restoration

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Neural Regeneration Research 2025年第3期20卷 660-670页

作者： ernesto Doncel-Pérez gabriel guízar-Sahagún Israel grijalva-Otero Hospital Nacional de Parapléjicos de Toledo Servicio de Salud de Castilla La Mancha(SESCAM)ToledoSpain Medical Research Unit for Neurological Diseases UMAE Hospital de EspecialidadesCentro Médico Nacional Siglo XXIIMSSCiudad de MéxicoMéxico

Spinal cord injury results in paralysis, sensory disturbances, sphincter dysfunction, and multiple systemic secondary conditions, most arising from autonomic dysregulation. All this produces profound negative psychosocial implications for affected people, their families, and their communities;the financial costs can be challenging for their families and health institutions. Treatments aimed at restoring the spinal cord after spinal cord injury, which have been tested in animal models or clinical trials, generally seek to counteract one or more of the secondary mechanisms of injury to limit the extent of the initial damage. Most published works on structural/functional restoration in acute and chronic spinal cord injury stages use a single type of treatment: a drug or trophic factor, transplant of a cell type, and implantation of a biomaterial. Despite the significant benefits reported in animal models, when translating these successful therapeutic strategies to humans, the result in clinical trials has been considered of little relevance because the improvement, when present, is usually insufficient. Until now, most studies designed to promote neuroprotection or regeneration at different stages after spinal cord injury have used single treatments. Considering the occurrence of various secondary mechanisms of injury in the acute and sub-acute phases of spinal cord injury, it is reasonable to speculate that more than one therapeutic agent could be required to promote structural and functional restoration of the damaged spinal cord. Treatments that combine several therapeutic agents, targeting different mechanisms of injury, which, when used as a single therapy, have shown some benefits, allow us to assume that they will have synergistic beneficial effects. Thus, this narrative review article aims to summarize current trends in the use of strategies that combine therapeutic agents administered simultaneously or sequentially, seeking structural and functional restoratio

关键词： neural regeneration neuroprotection spinal cord injury repair spinal cord injury treatments structural restoration of spinal cord injury

Dinophysoid dinoflagellates from subphotic depths:Amphisolenia ***,Dinofurcula tricornuta ***.,and Dinophysis profunda ***.(Dinophysales,Dinophyceae)

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Journal of Oceanology and Limnology 2022年第2期40卷 703-711页

作者： Fernando gÓmez Department of Biological and Environmental Sciences and Technologies University of SalentoLecce 73100Italy

Three species of dinophysoid planktonic dinoflagellates are described from the eastern Mediterranean *** *** was collected at 70-m depth in the Ionian *** small species showed a more asymmetric midbody and a proportionally longer neck when compared to the closer relative *** individuals of Dinofurcula tricornuta *** at 154-m depth in the Marmara Sea are characterized by three posterior-oriented processes when compared to its congeneric *** is the first record of the genus Dinofurcula beyond the eastern tropical Pacific *** profunda *** at 500-m depth in the Ionian Sea is characterized by ovate hypotheca and a serrate crest-like left sulcal list when compared to its close relative *** findings evidence an undescribed biodiversity in the under-sampled subphotic depths.

关键词： deep ocean Dinophyta Dinoflagellata Mediterranean Sea mesopelagic new species

Morphology and distribution of Pronoctiluca (Dinoflagellata, incertae sedis) in the Pacific Ocean

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Acta Oceanologica Sinica 2013年第4期32卷 71-76页

作者： gómez Fernando Department of Biological Oceanography Institute of Oceanography University of S o Paulo

The diversity and distribution of Pronoctiluca, a marine dinoflagellate of enigmatic systematic position, was studied in the vicinity of the Kuroshio and Oyashio Currents, the Philippines, Celebes, Sulu and South China Seas, western and central equatorial and southeast Pacific Ocean. The abundance of Pronoctiluca was high- er, with a wide vertical distribution, in eutrophic temperate regions, whereas it was nearly absent in surface waters of oligotrophic tropical regions. Most of the specimens corresponded to P. spinifera. Pronoctiluca pelagica, covered by hyaline layers and with no flagella, is considered as an encysted form. The bipartition was only observed in P. acuta-P, spinifera forms, that together with the occurrence of intermediate forms between P. spinifera and P. pelagica suggest that they may correspond to developmental stages of a single species. Pronoctiluca is essential to understanding the evolutionary history of the alveolates.

关键词： Alveolata basal dinoflagellates Dinophyceae heterotrophic flagellate Noctilucales plankton

Dicroerisma (Actiniscales, Dinophyceae) in the open Pacific Ocean, a gymnodinioid dinoflagellate with an endoskeleton

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Chinese Journal of Oceanology and Limnology 2008年第1期26卷 116-120页

作者： Fernando gómez Station Marine de Wimereux Université des Sciences et Technologies de Lille-Lille1 FRE 2816 ELICO CNRS 28 Avenue Foch BP 80 F-62930 Wimereux France

This study is the first to describe and illustrate the dinoflagellate genus Dicroerisma in the open Pacific Sea and in the southern hemisphere. Eleven individuals ascribed to Dicroerisma psilonereiella were encountered in subsurface waters (>70 m depth) from 34°N to 33°S. Another specimen that differs from the type is also illustrated. These findings reveal that Dicroerisma is a widespread genus and that there is tentative existence of another species within the genus.

关键词： Dicroerisma psilonereiella Actiniscales axostyle endoskeleton Dinophyceae the Pacific Ocean

Lessons from International Students’ Reaction to the 2011 great East Japan Earthquake:The Case of the School of Engineering at Tohoku University

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International Journal of Disaster Risk Science 2013年第3期4卷 137-149页

作者： Oscar A.gómez graduate School of global Studies Doshisha UniversityKyoto 602-0898Japan

The objective of this study is to document the reaction of international students to the 11 March 2011 emergency in order to inform and improve disaster management strategies, both public and institutional. The study is based mainly on a questionnaire survey carried out in August 2011 and follow-up interviews with students and other stakeholders. It describes the background of Tohoku University’s School of Engineering and covers six different stages in the evolution of the emergency:(1) immediate response;(2) taking shelter in Sendai;(3) life in the city during the aftermath;(4) sheltering outside Sendai;(5) coming back;plus(6) an overview of the experience. Major findings include: the process of evacuation and safety confirmation was successful, yet the subsequent phases(2 and 3) went on mostly unmanaged;students relied mostly on secondary sources of information to make decisions, mainly family and friends of the same nationality, most of whom probably were not better informed than the students themselves. Based on the findings, suggestions for future disaster planning are advanced, as well as a discussion on the challenges of information provision during crisis.

关键词： disaster mostly great

An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

Zeckendorf representations with at most two terms to x-coordinates of Pell equations

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Science China Mathematics 2020年第4期63卷 627-642页

作者： Carlos A.gómez Florian Luca Departamento de Matematicas Universidad del ValleCali 25360Colombia School of Mathematics University of the WitwatersrandWits 2050South Africa Max Planck Institute for Mathematics Bonn 53111Germany Department of Mathematics Faculty of SciencesUniversity of OstravaOstrava 70103Czech Republic

In this paper,we find all positive squarefree integers d satisfying that the Pell equation X^2-d Y^2=±1 has at least two positive integer solutions(X,Y)and(X′,Y′)such that both X and X′have Zeckendorf representati... 详细信息

关键词： Pell equation Fibonacci numbers lower bounds for linear forms in logarithms reduction method

Coarse-graining auto-encoders for molecular dynamics

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npj Computational Materials 2019年第1期5卷 48-56页

作者： Wujie Wang Rafael gómez-Bombarelli Department of Materials Science and Engineering Massachusets Institute of Technology77 Massachusetts AvenueCambridgeMA 02319USA

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of condensed-phase materials and,as a predictive tool,enable computational design of new ***,because of the large spatial and temporal scales of thermodynamic and kinetic phenomena in materials,atomistic simulations are often computationally ***-graining methods allow larger systems to be simulated by reducing their dimensionality,propagating longer timesteps,and averaging out fast ***-graining involves two coupled learning problems:defining the mapping from an all-atom representation to a reduced representation,and parameterizing a Hamiltonian over coarse-grained *** propose a generative modeling framework based on variational auto-encoders to unify the tasks of learning discrete coarse-grained variables,decoding back to atomistic detail,and parameterizing coarse-grained force *** framework is tested on a number of model systems including single molecules and bulk-phase periodic simulations.

关键词： dynamics representation steps