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低频电刺激联合穴位贴敷对人工流产术后子宫康复效果及月经恢复时间的影响观察

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中国现代药物应用 2024年第10期18卷 138-141页

作者：张宇枣庄市妇幼保健院 277100

目的探究对人工流产术后患者给予低频电刺激联合穴位贴敷治疗的有效性,并观察对其子宫康复效果、月经恢复时间的影响。方法选取70例人工流产术患者,根据电脑随机法将其分成对照组和观察组,每组35例。对照组将低频电刺激作为治疗方案,观... 详细信息

目的探究对人工流产术后患者给予低频电刺激联合穴位贴敷治疗的有效性,并观察对其子宫康复效果、月经恢复时间的影响。方法选取70例人工流产术患者,根据电脑随机法将其分成对照组和观察组,每组35例。对照组将低频电刺激作为治疗方案,观察组将低频电刺激联合穴位贴敷作为治疗方案。比较两组治疗前后性激素(血清人绒毛膜促性腺激素、孕酮以及雌二醇)、子宫血流动力学指标[搏动指数(PI)、阻力指数(RI)、收缩期峰值血流与舒张期末流速比(S/D)]及康复效果、月经恢复时间、子宫内膜厚度。结果两组治疗后血清人绒毛膜促性腺激素、孕酮以及雌二醇水平较同组治疗前均降低,且观察组血清人绒毛膜促性腺激素(153.78±31.40)mIU/ml、孕酮(15.16±3.14)ng/ml以及雌二醇(56.47±9.63)pg/ml低于对照组的(188.69±36.21)mIU/ml、(17.14±4.05)ng/ml、(60.75±5.29)pg/ml,差异有统计学意义(P<0.05)。两组治疗后子宫内膜螺旋动脉RI、PI、S/D较本组治疗前均降低,且观察组子宫内膜螺旋动脉RI(0.51±0.10)、PI(0.75±0.11)、S/D(2.18±0.17)低于对照组的(0.59±0.06)、(0.86±0.19)、(2.43±0.21),差异有统计学意义(P<0.05)。观察组康复总有效率91.43%高于对照组的71.43%,差异有统计学意义(P<0.05)。观察组月经恢复时间以及子宫内膜厚度均优于对照组,差异有统计学意义(P<0.05)。结论临床将低频电刺激联合穴位贴敷应用于人工流产术后方法可行,其能够改善患者性激素、子宫血流动力学,提升子宫康复效果,促进月经早日恢复。

关键词：低频电刺激穴位贴敷人工流产术子宫康复月经恢复

温针灸联合小建中汤加减治疗在脾胃虚寒型消化性溃疡中的临床效果观察

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中国实用医药 2024年第6期19卷 10-14页

作者：余立北京鹤年堂中医医院 100000

目的研究温针灸联合小建中汤加减治疗在脾胃虚寒型消化性溃疡中的临床效果。方法 80例脾胃虚寒型消化性溃疡患者,按照住院号录入系统后,采取住院号尾数奇偶性分为对照组(奇数)与观察组(偶数),每组40例。对照组服用小建中汤加减治疗,观... 详细信息

目的研究温针灸联合小建中汤加减治疗在脾胃虚寒型消化性溃疡中的临床效果。方法 80例脾胃虚寒型消化性溃疡患者,按照住院号录入系统后,采取住院号尾数奇偶性分为对照组(奇数)与观察组(偶数),每组40例。对照组服用小建中汤加减治疗,观察组服用小建中汤加减治疗的同时采取温针灸治疗。比较两组临床疗效、临床改善情况、中医证候积分、临床相关指标[血清表皮生长因子(EGF)、胃液EGF、胃黏膜表皮生长因子受体(EGFR)(积分光密度、面积百分比)、血清一氧化氮(NO)、白细胞介素-10(IL-10)]。结果观察组的总有效率95.00%高于对照组的77.50%(Png/ml、胃液EGF(0.83±0.16)ng/ml、积分光密度(1.78±0.23)D、面积百分比(28.72±4.12)%高于对照组的(0.43±0.10)ng/ml、(0.47±0.20)ng/ml、(1.34±0.24)D、(21.52±3.87)%(Png/L高于对照组的(62.14±10.25)μmol/L、(110.57±5.44)ng/L(P<0.05)。结论脾胃虚寒型消化性溃疡通过采取温针灸联合小建中汤加减治疗后临床效果提高,可有效改善患者的临床症状及相关临床指标,减轻患者的痛苦,促进患者尽快恢复,具有较高的临床应用价值。

关键词：脾胃虚寒型消化性溃疡小建中汤温针灸

调强放疗同步化疗对中晚期食管癌患者血清肿瘤标志物水平、生活质量的影响

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反射疗法与康复医学 2024年第9期5卷 149-151,159页

作者：王瑜新泰市人民医院肿瘤二科山东泰安271200

目的探讨调强放疗同步化疗在中晚期食管癌患者中的应用效果。方法选取新泰市人民医院2020年6月—2023年6月收治的64例中晚期食管癌患者为研究对象,按随机数字表法将其分为对照组和观察组,每组32例。两组均行化疗,在此基础上,对照组进行... 详细信息

目的探讨调强放疗同步化疗在中晚期食管癌患者中的应用效果。方法选取新泰市人民医院2020年6月—2023年6月收治的64例中晚期食管癌患者为研究对象,按随机数字表法将其分为对照组和观察组,每组32例。两组均行化疗,在此基础上,对照组进行常规放疗,观察组进行调强放疗。比较两组患者的临床效果及安全性。结果观察组的临床疗效为93.75%,高于对照组的75.00%,差异有统计学意义(Png/mL、(1.04±0.22)μg/mL,均低于对照组的(1.91±0.32)μg/mL、(1.78±0.28)ng/mL、(1.38±0.25)μg/mL,组间差异有统计学意义(P0.05)。结论调强放疗同步化疗可提高中晚期食管癌的控制效果,降低患者血清肿瘤标志物水平,更好地改善其生活质量,安全可行。

关键词：中晚期食管癌调强放疗化疗肿瘤标志物生活质量

独活寄生汤配合温针灸治疗类风湿性关节炎的效果分析

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中国实用医药 2024年第8期19卷 149-151页

作者：于龙辽阳市中医院 111000

目的探究对类风湿性关节炎患者使用独活寄生汤配合温针灸治疗的效果。方法 82例类风湿性关节炎患者作为研究对象,随机分为对照组(n=41)、观察组(n=41)。对照组给予常规治疗,观察组给予独活寄生汤配合温针灸治疗。比较两组患者的临床症... 详细信息

目的探究对类风湿性关节炎患者使用独活寄生汤配合温针灸治疗的效果。方法 82例类风湿性关节炎患者作为研究对象,随机分为对照组(n=41)、观察组(n=41)。对照组给予常规治疗,观察组给予独活寄生汤配合温针灸治疗。比较两组患者的临床症状(关节肿胀数目、关节压痛数目、晨僵时间)变化情况,炎症因子[肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞介素-1(IL-1)、白细胞介素-6(IL-6)]水平。结果治疗前,两组关节肿胀数目、关节压痛数目、晨僵时间对比,差异无统计学意义(P>0.05);治疗后,两组关节肿胀数目、关节压痛数目少于治疗前,晨僵时间短于治疗前,且观察组关节肿胀数目(3.12±1.24)个、关节压痛数目(5.12±2.18)个少于对照组的(4.33±2.07)、(7.23±2.88)个,晨僵时间(25.44±9.11)min短于对照组的(32.73±14.82)min,差异显著(P0.05);治疗后,两组IL-1、IL-6、TNF-α、CRP低于治疗前,且观察组IL-1(32.55±2.76)ng/L、IL-6(16.34±5.11)ng/L、TNF-α(3.83±1.16)pg/ml、CRP(9.18±2.15)mg/L低于对照组的(41.31±3.58)ng/L、(23.06±1.38)ng/L、(7.84±2.52)pg/ml、(18.36±2.41)mg/L,差异显著(P<0.05)。结论独活寄生汤配合温针灸治疗,可有效改善类风湿性关节炎患者的临床症状,减轻炎症反应,对患者预后改善有积极影响,值得推广。

关键词：独活寄生汤温针灸类风湿性关节炎

A guide to use fluorinated aromatic bulky cations for stable and high-performance 2D/3D perovskite solar cells:The more fluorination the better?

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Journal of Energy Chemistry 2022年第1期31卷 179-189,I0006页

作者： Lei Wang Qin Zhou Zilong Zhang Wenbo Li Xiaobing Wang Qi ng Tian Xiaoyan yu Ting Sun Jihuai Wu Bao Zhang Peng Gao School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002FujianChina Laboratory for Advanced Functional Materials.Xiamen Institute of Rare Earth Materials Haixi InstituteChinese Academy of SciencesXiamen 361021FujianChina College of Materials Science and Engineering Huaqiao University361021 XiamenFujianChina

While serious stability issues impede the commercialization of perovskite solar cells(PSCs),two-dime nsional(2D)perovskites based on fluorinated bulky cations have emerged as more intrinsically stable ***,the influence of fluorination degree of the bulky aromatic cation on the per-formance of resulting PSCs has not been ***,2D perovskites(FxPEA)_(2)PbI_(4)(x=1,2,3,5)are grown in situ on the surface of the three-dime nsion al(3D)perovskite and dem on strate effective passivation of the surface defects of 3D *** power conversion efficiency(PCE)of the optimized devices were boosted from 20.75%for the control device to 21.09%,22.06%,22.74%and 21.86%for 2D/3D devices treated with 4-fluorophenethylamine iodide,3,5-difluorophenylethylamine iodide,2,4,5-trifluoroethylphenylethylamine iodide,and 1,2,3,4,5-pentafluorophenylethylamine iodide,*** firstly reported two unexplored RP-type layered perovskites with F_(2)PEAI and F_(3)PEAI as bulky *** combined experimental and theoretical analysis revealed the reasons behind the various morphology,device performances,dynamic behavior,and humidity *** best performing F_(5)PEAI-treated device retaining 95.0%of its initial PCE under ambient atmosphere(with RH of 60%±5%)without encapsulation for 300 h *** work provides useful guidance for selecting fluorinated bulky cations with different molecular electronic properties,which will play an essential role in further improving the performance/stability of PSCs for the sake of further commercialization.

关键词： 2D perovskite Fluorinated spacer cation Perovskite solar cells Passivation Stability

Intratumoral Bacteria Dysbiosis Is Associated with Human Papillary Thyroid Cancer and Correlated with Oncogenic Signaling Pathways

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Engineering 2023年第9期28卷 179-192页

作者： Shuang yu Yanqiang Ding Xuejie Wang Siu Kin ng Siting Cao Weixin Liu Zhuming Guo yubin Xie Shubin Hong Lixia Xu Xiaoxing Li Jie Li Weiming Lv Sui Peng Yanbing Li Joseph J.Y.Sung Jun yu Haipeng Xiao Department of Endocrinology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Institute of Digestive Disease and Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseThe Chinese University of Hong KongHong Kong 999077China Department of Head and Neck Surgery Sun Yat-Sen University Cancer CenterGuangzhou 510060China Clinical Trials Unit The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Institute of Precision Medicine The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Department of Oncology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Department of Breast and Thyroid Surgery The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Lee Kong Chian School of Medicine Nanyang Technology UniversitySingapore 308232Singapore

Emerging evidence suggests that microbial dysbiosis plays vital roles in many human ***,knowledge of whether the microbial community in thyroid tumor is related to tumorigenesis remains *** this study,we aimed to explore the microbial community in thyroid tissues and its contribution to papillary thyroid cancer(PTC).In parallel,we performed microbial profiling and transcriptome sequencing in the tumor and adjacent normal tissues of a large cohort of 340 PTC and benign thyroid nodule(BTN)*** microbial signatures were identified in PTC,BTN,and their adjacent nontumor ***-thyroid tissue bacteria were verified by means of bacteria staining,fluorescence in situ hybridization,and immunoelectron *** found that 17 bacterial taxa were differentially abundant in PTC compared with BTN,which included enrichment in PTC of the pathobionts Rhodococcus,Neisseria,Streptococcus,Halomonas,and Devosia,and depletion of the beneficial bacteria *** differentially abundant bacteria could differentiate PTC tumor tissues(PTC-T)from BTN tissues(BTN-T)with an area under the curve(AUC)of 81.66%.Microbial network analysis showed increased correlation strengths among the bacterial taxa in PTC-T in comparison with ***-corresponding bacteria(i.e.,Erwinia,Bacillus,and Acinetobacter)were found to be enriched in PTC with Hashimoto’s ***,our integrative analysis revealed that the PTC-enriched bacteria had a positive association with key PTC-oncogenic pathway-related genes,including BRAF,KRAS,IRAK4,CTNNB1,PIK3CA,MAP3K7,and *** conclusion,our results suggest that intratumor bacteria dysbiosis is associated with the thyroid tumorigenesis and oncogenic signaling pathways of PTC.

关键词： Papillary thyroid cancer Benign thyroid nodule Bacteria Transcriptome Hashimoto’s thyroiditis

电感耦合等离子体质谱法测定锌电解液中铊含量的研究

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世界有色金属 2024年第12期 12-14页

作者：于亮杨月郑丽霞株洲冶炼集团股份有限公司

建立了使用电感耦合等离子体质谱仪测定锌湿法冶炼电解液中铊含量的方法，样品经过稀释在稀硝酸介质中，205Tl为测量同位素，以He作为碰撞气体，185Re作内标校正干扰，用工作曲线法计算铊的含量。该方法测定锌电解液中铊含量的检出限为0... 详细信息

建立了使用电感耦合等离子体质谱仪测定锌湿法冶炼电解液中铊含量的方法，样品经过稀释在稀硝酸介质中，205Tl为测量同位素，以He作为碰撞气体，185Re作内标校正干扰，用工作曲线法计算铊的含量。该方法测定锌电解液中铊含量的检出限为0.2ng/L，相对标准偏差小于5%，方法试验回收率在96%～101.1%之间，具有良好的准确度和精密度。

关键词： ICP-MS 锌电解液铊

来源：博看期刊

Modeling the high-energy emission from the gamma-ray binary 1FGL J1018.6–5856

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Research in Astronomy and Astrophysics 2021年第8期21卷 46-58页

作者： A-Ming Chen Chowing ng Jumpei Takata yun-Wei yu School of physics Huazhong University of Science and TechnologyWuhan 430074China Department of Physics The University of Hong KongPokfulam RoadHong KongChina College of Physical Science and Technology Central China Normal UniversityWuhan 430079China

1FGL J1018.6–5856 is a high mass gamma-ray binary containing a compact object orbiting around a massive star with a period of 16.544 *** the compact object is a pulsar,non-thermal emissions are likely produced by electrons accelerated at the termination shock,and may also originate from the magnetosphere and the un-shocked wind of the *** this paper,we investigate the non-thermal emissions from the wind and the shock with different viewing geometries and study the multi-wavelength emissions from 1FGL J1018.6–*** present the analysis results of the Fermi/LAT using nearly 10 years of *** phase-resolved spectra indicate that the Ge V emissions comprise a rather steady component that does not vary with orbital motion and a modulated component that shows flux maximum around inferior *** ke V/Te V light curves of 1FGL J1018.6–5856 also exhibit a sharp peak around inferior conjunction,which are attributed to the boosted emission from the shock,while the broad sinusoidal modulations could be originating from the deflected shock tail at a larger *** modulations of Ge V flux are likely caused by the boosted synchrotron emission from the shock and the IC emission from the unshocked pulsar wind,while the steady component comes from the outer gap of the pulsar ***,we discuss the similarities and differences of 1FGL J1018.6–5856 with other binaries,like LS 5039.

关键词： binaries:close gamma rays:stars X-rays:binaries radiation mechanisms:non-thermal

四烯甲萘醌联合PKP术治疗骨质疏松性椎体压缩骨折患者的临床研究

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中国临床药理学杂志 2024年第10期40卷 1409-1413页

作者：朱衍邱雷雨周筱诸暨市人民医院脊柱外科浙江诸暨311800 诸暨市人民医院介入科浙江诸暨311800 诸暨市人民医院内分泌科浙江诸暨311800

目的观察四烯甲萘醌联合经皮球囊扩张椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩骨折(OVCF)患者的临床疗效及安全性。方法将OVCF患者用随机数字表法分为试验组和对照组。对照组予以PKP术及常规抗骨质疏松治疗,试验组在对照组基础上加... 详细信息

目的观察四烯甲萘醌联合经皮球囊扩张椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩骨折(OVCF)患者的临床疗效及安全性。方法将OVCF患者用随机数字表法分为试验组和对照组。对照组予以PKP术及常规抗骨质疏松治疗,试验组在对照组基础上加用四烯甲萘醌15 mg,tid,连续治疗6个月,比较2组骨密度T值、Oswestry功能障碍指数(ODI)、视觉模拟评分(VAS)、骨代谢指标[骨钙素(OC)、碱性磷酸酶(ALP)、Ⅰ型胶原交联C-末端肽(CTX-Ⅰ)、25羟维生素D(25(OH)D)]变化,记录2组再骨折和药物不良反应发生情况。结果试验组和对照组各40例。治疗后,试验组和对照组的腰椎L2-4骨密度T值分别为-1.79±0.24和-2.16±0.28,股骨颈骨密度T值分别为-1.44±0.16和-2.01±0.22,股骨大转子骨密度T值分别为-1.76±0.18和-1.97±0.23,在统计学上差异均有统计学意义(均Png·mL^(-1),25(OH)D分别为(30.14±3.28)和(26.55±2.73)ng·mL^(-1),在统计学上差异均有统计学意义(均P0.05)。结论四烯甲萘醌联合PKP可明显提高OVCF患者骨密度,改善骨代谢指标,减少腰椎功能障碍及疼痛,不增加再骨折风险和药物不良反应发生率。

关键词：四烯甲萘醌胶囊骨质疏松性椎体压缩骨折经皮球囊扩张椎体后凸成形术骨代谢