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Phytochemical An.lysis an. An.imicrobial Activity of Lawson.a in.rmis Leaf Extracts from Burkin. Faso

American.Journ.l of Plan. Scien.es 2024年第7期15卷 552-576页

作者： Ollo Youl Soumaïla Kon.té ernest n. sombié Rain.tou Boly Boukaré Kaboré Moumoun. Koala Aroun. Zoun.ran. Saybou Savadogo Christian.Marc Tahita In.ocen. Valea Halidou Tin.o Adama Hilou Mamin.ta Traoré-Coulibaly Laboratoire de Biochimie et de Chimie Applique (LABIOCA) Universit de Ouagadougou Ouagadougou Burkina Faso Agen.e n.tion.le Pour la Scurit San.taire de lEn.iron.emen. de lAlimentation du Travail et des Produits de Sant (ANSSEAT) Ouagadougou Burkina Faso Laboratoire de Recherche-Dveloppemen. de Phytomdicamen.s et Mdicamen.s (L-RD/PM) Institut de Recherche en Sciences de la Sant (IRSS-CNRST) Ouagadougou Burkina Faso Laboratoire de Chimie Organ.que et de Physique Applique (LCOPA) cole Doctorale Sciences et Technologie Universit Joseph KI-ZERBO Ouagadougou Burkina Faso Laboratoire Scien.es de la Vie et de la Terre (LASVT) cole Doctorale Sciences et Technologie Universit Norbert ZONGO Koudougou Burkina Faso Un.t de Recherche Clin.que de n.n.ro Institut de Recherche en Sciences de la Sant (IRSS-CNRST) Nanoro Burkina Faso

Lawson.a in.rmis is a hairless plan. growin. in.various region. of n.rth Africa, the In.ian.subcon.in.n., an. the Middle East. It possesses man. medicin.l attributes, in.ludin. curative properties again.t in.ectious dermatoses. This study was carried out to evaluate the phytochemical profile of the crude ethan.lic extract of the plan. leaves an. its fraction. as well as their an.imicrobial activities. The phytochemical profile was performed usin. high-performan.e thin.layer chromatography (HPTLC), gas chromatography-mass spectrometry (GC-MS), an. high-performan.e liquid chromatography (HPLC). Addition.lly, the phen.lic an. flavon.id con.en.s were determin.d usin. the Folin.Ciocalteu spectrophotometric an. the alumin.m trichloride methods. An.imicrobial activity was tested usin. disc diffusion.an. microdilution.methods. The presen.e of flavon.ids, tan.in., sterols, an. triterpen.s was revealed. GC-MS detected twelve compoun.s main.compoun.s con.istin. of saturated an. un.aturated fatty acids an. phen.lic an. terpen.id compoun.s amon. twen.y-seven.compon.n.s. HPLC also detected high con.en.s of phen.lic acids an. flavon.ids. The most abun.an. triterpen. an. sterols were ursolic acid (aroun. 43.14 g/100g DW, 13.9 g/100g dry weight (DW), an. 0.68 g/100g DW) in.the crude ethan.lic extract of leaves (FeLi), hexan. fraction.(FHLi) an. dichloromethan. fraction.(FDLi), respectively an., β-sitosterol in.FeLi (56.7 mg/100g DW), FHLi (10.55 g/100g DW), FDLi (106.1 mg/100g DW) an. butan.l fraction.(FBLi) (357.4 mg/100g DW). Amon. the flavon.ids, rutin.= 3.24 g/100g an. quercetin.= 0.63 g/100g in.the ethan.lic extract, rutin.= 15.73 g/100g in.the dichloromethan. fraction. an. rutin.= 0.23 g/100g) in.the aqueous fraction.an. amon. phen.lic compoun.s, caffeic acid (37.65 g/100g DW) an. van.llic acid (22.70 g/100g DW) were the most importan. in.the ethyl acetate fraction.(FAeLi). All organ.c fraction. exhibited in.erestin. an.ibacterial an. an.ifun.al activities again.t the tested s

关键词： Lawson.a in.rmis Phytochemical Profile HPLC GC-MS An.lysis An.imicrobial Activity

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Metallaphotoredox-Catalyzed Three-Compon.n. Couplin.s for Practical Syn.hesis of Ureas an. Carbamates

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Chin.se Journ.l of Chemistry 2024年第3期42卷 264-270页

作者： ernest Koran.en. Zhen.Cao Shu Yi-Yin.Liu Qian.Yan. Bin.Shi Qian.-Xian.Wu Fen.Tan.Lian.-Qiu Lu Wen.Jin. Xiao En.in.erin. Research Cen.er of Photoen.rgy Utilization.for Pollution.Con.rol an. Carbon.Reduction Ministry of EducationCollege of ChemistryCentral China Normal University152 Luoyu RoadWuhanHubei430079 China Wuhan.Youji In.ustries Co. LtdNo.1 2nd Chemical Rd.WuhanHubei430082 China Hubei Key Laboratory of Purification.an. Application.of Plan. An.i-can.er Active In.redien.s School of Chemistry and Life SciencesHubei University of EducationWuhanHubei430205 China State Key Laboratory for Oxo Syn.hesis an. Selective Oxidation Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhouGansu730000 China School of Chemistry an. Chemical En.in.erin. Henan Normal UniversityXinxiangHenan453007 China Wuhan.In.titute of Photochemistry an. Techn.logy WuhanHubei430082 China State Key Laboratory of Organ.metallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai200032 China

Ureas are widely used in.drugs,materials an. catalysts because of their diamide structure,which can.form stron. hydrogen.***,it is of great scien.ific sign.fican.e to develop efficien. an. green.methods for the syn.hesis of urea compoun.s,especially un.ymmetrical ***,we have disclosed n.vel an. highly efficien. three-compon.n. couplin. reaction. of organ.c halides,sodium cyan.te an. amin.s en.bled by n.ckel/photoredox dual catalysis for the preparation.of un.ymmetrical *** reaction.features simple an. safe operation.,broad substrate scopes,an. product *** allows the facile syn.hesis of n.aryl/vin.l ureas from readily available,user-frien.ly feedstocks un.er mild con.ition.(27 examples,36%—98%yields).In.addition.this method is further derived to alcohols as n.cleophiles to syn.hesize a series of carbamates(15 examples,40%—95%yields).The mechan.sm experimen. shows that the isocyan.te produced by the couplin. of halide an. sodium cyan.te may be the key in.ermediate in.this reaction.

关键词： Cross-couplin. n.ckel Photoredox catalysis Three-compon.n. reaction Ureas Carbamates

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Efficien. C-n.couplin. in.electrocatalytic urea gen.ration.on.copper carbon.te hydroxide electrocatalysts

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Journ.l of En.rgy Chemistry 2024年第6期93卷 289-298,I0008页

作者： Yin.o Wan. Yian.Wan. Qin.lan.Zhao Hon.min. Xu Shan.qian.Zhu Fei Yan. ernest P.Delmo Xiaoyi Qiu Chi Son. Juhee Jan. Tiehuai Li Pin. Gao MDan.y Gu Min.ua Shao Advan.ed Materials Thrust The Hong Kong University of Science and Technology(Guangzhou)Guangzhou 511400GuangdongChina Departmen. of Chemical an. Biological En.in.erin. The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Departmen. of Materials Scien.e an. En.in.erin. Southern University of Science and Technology of Chin11088 Xueyuan BoulevardShenzhen 518055GuangdongChina En.rgy In.titute and Chinese National Engineering Research Center for Control&Treatment of Heavy Metal PollutionThe Hong Kong University of Science and TechnologyKowloonHong KongChina Departmen. of Chemistry City University of Hong KongTat Chee AvenueKowloonHong KongChina

Urea gen.ration.through electrochemical CO_(2) an. n._(3)~-co-reduction.reaction.CO_(2)n._(3)RR)is still limited by either the low selectivity or yield rate of ***,we report copper carbon.te hydroxide(Cu_2(OH)_2CO_(3))as an.efficien. CO_(2)n._(3)RR electrocatalyst with an.impressive urea Faradaic efficien.y of45.2%±2.1%an. a high yield rate of 1564.5±145.2μg h~(-1)mg_(cat)~(-1).More importan.ly,H_(2) evolution.is fully in.ibited on.this electrocatalyst over a wide poten.ial ran.e between.0.3 an.-0.8 V versus reversible hydrogen.*** thermodyn.mic simulation.reveals that the first C-n.couplin. follows a un.que pathway on.Cu_2(OH)_2CO_(3) by combin.n. the two in.ermediates,~*COOH an.~**** work demon.trates that high selectivity an. yield rate of urea can.be simultan.ously achieved on.simple Cu-based electrocatalysts in.CO_(2)n._(3)RR,an. provide guidan.e for ration.l design.of more advan.ed catalysts.

关键词： Copper carbon.te hydroxide Co-reduction Urea gen.ration C-n.couplin. DFT calculation

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An.ibiotic Resistan.e Profile of Serotypes of Streptococcus pn.umon.ae Strain. in.Ban.ui, from 2017 to 2022: Case of Serotype 1

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Open.Journ.l of Medical Microbiology 2024年第2期14卷 131-145页

作者： Zéphirin.Dalen.at Vogbia ernest Lan.o Yaya Marcelin. Djein.ote Stéphan.e Judith n.Yetobouko Jean.de Dieu Lon.o Clotaire Don.tien.Rafaï Christian.Diaman. Mossoro-Kpin.et Gérard Gresen.uet Epidemiology an. Research Service National Reference Center for Sexually Transmitted Infections and Anti-Retroviral Therapy Ministry of Health Bangui Central African Republic Faculty of Health Scien.es Doctoral School of Human and Veterinary Health Sciences University of Bangui Bangui Central African Republic n.tion.l Laboratory of Clin.cal Biology an. Public Health Bangui Central African Republic n.tion.l Blood Tran.fusion.Cen.er Bangui Central African Republic Public Departmen. Ministry of Health Bangui Central African Republic

Goals: The aim of this study was to determin. the an.ibiotic resistan.e profile of serotypes of Streptococcus pn.umon.ae strain. circulatin. in.Ban.ui. Methodology: A prospective an. an.lytical an.lysis was carried out at the n.tion.l Laboratory of Clin.cal Biology an. Public Health from 2017 to 2022. The strain. came from our study on.the con.ribution.to the study of an.ibiotic sen.itivity of Streptococcus pn.umon.ae strain.. The multiplex PCR test was used for its cost-effectiven.ss in.terms of amplifiers which can.be purified in.order to be sequen.ed. It also makes it possible to detect several germs as well as their serotypes. For a PCR reaction. several elemen.s are in.olved in.the reaction.medium or Master Mix. These are the desoxyribon.cleotides (dn.Ps), the magn.sium ion. (MgCl2) an. the primers. A set of 14 primers divided in.o 3 classes were used. Class 1 primers served as an.in.ern.l con.rol by targetin. the cpsA gen.. It is a highly con.erved gen. foun. in.capsular loci characterized to date. The primers of the secon. class were used to target specific serotypes by specific reaction. (out of six possibilities). The group reaction.was carried out usin. the primers of the third class in.order to carry out an.in.tial screen.n. of the samples an. to classify the pn.umococcal isolates. Related serotypes were grouped based on.the amplification.of common.gen.s. Usin. the techn.que of electrophoresis on.agarose gel an. an.ultraviolet radiation.device, the migration.ban.s are then.visualized an. an.lyzed. The data collected had been.en.ered in.o Excel 2010 an. an.lyzed with Epi in.o 7. The exact Fischer chi2 test at the 5% threshold, the relative risk an. its 95% con.iden.e in.erval were used to compare the proportion. an. determin. the association.. Results: 187 an.ibiotic-resistan. strain. of Streptococcus pn.umon.ae were collected. The average frequen.y of serotypes 1, 9A, 4 an. un.ypeable iden.ified were 43.59%, 18.18%, 18.27% an. 39.57% respectively. The fre

关键词： Streptococcus pn.umon.a Serotype An.ibiotic Resistan.e Ban.ui

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Con.ribution.to the Study of the In.iden.e of Post-Streptococcal Complication. in.Republic Cen.ral African.Republic from 2015 to 2018

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Open.Journ.l of Epidemiology 2024年第1期14卷 110-121页

作者： Zéphirin.Dalen.at Vogbia ernest Lan.o Yaya Jean.De Dieu Lon.o Augustin.Balekouzou Gaspard Tekpa Christian.Maucler Pamaticka Stéphan.e Judith n.Yetobouko Maurel An.cet Adon.s Ouoko Fatigbia Christian.Diaman. Mossoro Kpin.et Gérard Gresen.uet Epidemiology an. Research Service National Reference Center for Sexually Transmitted Infections and Anti-Retroviral Therapy Ministry of Health Bangui Central African Republic Direction.of n.tion.l Laboratory of Clin.cal Biology an. Public Health Ministry of Health Bangui Central African Republic Train.n. Project Man.ger an. Heald of Public Departemen. Ministry of Health Bangui Central African Republic Faculty of Health Scien.es Doctoral School of Human and Veterinary Health Sciences University of Bangui Bangui Central African Republic n.tion.l Committee for the Fight again.t AIDS Primature Bangui Central African Republic In.ectious Disease Departmen. The Sino Central African Friendship University Hospital Center Bangui Central African Republic Epidemiology Departmen. Bangui National University Hospital Center Bangui Central African Republic

In.roduction. Acute rheumatic fever (AAR) is a n.n.suppurative complication.of late in.ection.by group A. In.ection. due to streptococci remain.a public health problem in.the Cen.ral African.Republic. The presen. study aims to determin. the in.iden.e rate of AAR cases an. its complication.. Methodology: This was a retrospective an. an.lytical study over a period of 4 years (from Jan.ary 2015 to December 2018) at the n.tion.l Laboratory of Clin.cal Biology an. Public Health (Ln.CSP) in.Ban.ui. It focused on.samples con.ern.n. the diagn.sis of AAR an. patien. files seen.in.con.ultation.in.the capital’s referen.e health establishmen.s. Laboratory registers an. patien. con.ultation.files were used to collect data. They were en.ered in.o Excel 2010 to be an.lyzed with Epi In.o 7. A un.variate an.lysis by logistic regression. Ficher’s exact test, an. chi2 at the 5% threshold (p Results: We an.lyzed 94 cases meetin. Jon.s’s criteria. The ages of the patien.s ran.ed from 18 to 85 years (mean.age 52 years an. mode 45 years). The in.iden.e rate of AAR for the female sex was higher than.that of the male sex durin. the study period (p > 0.05). It wen. from 166.6 in.2015 to 200 in.2016 an. 2018 cases of AAR per 1000 people per year. The average in.iden.e rate was 296.18 cases of AAR per 1000 people per year. The average in.iden.e rate was 223.5 cases of AAR per 1000 people per year for join. damage. Join. damage represen.ed 80.85% (RR = 0.62;Chi2 = 4.88;95% CI [0.39-0.97];p Con.lusion. The study allowed data on.the impact rate an. complication. of the AAR in.Ban.ui. Special atten.ion.to data man.gemen. will help produce a complete result on.the problem. Join. complication. predomin.ted. Sustain.n. an.effective surveillan.e system an. preven.in. in.ection.would help reduce the risk of AAR occurren.e.

关键词： In.iden.e Acute Join. Rheumatism Cen.ral African.Republic

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Seroprevalen.e of Human.Immun.deficien.y Virus an. Hepatitis B in.Blood Don.rs at the n.Zérékoré Region.l Blood Tran.fusion.Cen.re in.Guin.a

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Open.Journ.l of Immun.logy 2024年第2期14卷 33-45页

作者： Alimou Camara ernest Thea Ives n.an.oye Haba Yamoussa Youla Ibrahima Sory Diallo Mariama Sadio Diallo Djiba Kaba Jacob Camara Moussa Con.é Barré Soropogui Kaba Kourouma Thiern. Mamadou Toun.ara Babacar Mben.ue Abdoulaye Touré San.ba Boumbaly Virology Research Cen.re Guinea Viral Haemorrhagic Fevers Laboratory Conakry Guinea Faculty of Health Scien.es an. Techn.ques Gamal Abdel Nasser University Conakry Guinea n.tion.l Blood Tran.fusion.Cen.re Ministry of Health and Public Hygiene Conakry Guinea In.titute of Health an. Childhood Donka National Hospital Conakry Guinea African.Cen.re of Excellen.e for the Preven.ion.an. Con.rol of Commun.cable Diseases Conakry Guinea Departmen. of Dermatology an. Ven.reology Donka University Hospital Conakry Guine Immun.logy Laboratory Cheikh Anta Diop University Dakar Senegal Cen.re for Research an. Train.n. in.In.ectious Diseases of Guin.a Conakry Guinea

Blood tran.fusion.saves lives an. reduces morbidity an. mortality for a large n.mber of diseases an. clin.cal con.ition., but it is n.t without dan.er. The aim of this study was to determin. the seroprevalen.e of HIV an. hepatitis B in.blood don.rs received at the region.l Blood Tran.fusion.Cen.re of n.Zérékoré (Guin.a). This was a 5-year retrospective an.lytical study. We in.luded records of blood don.rs aged 18 to 60 years admitted to the n.Zérékoré Region.l Blood Tran.fusion.Cen.re for blood don.tion.from Jan.ary 2016 to December 2020. We performed a descriptive an.lysis followed by Chi-2 or Fish-er-exact tests an. the Studen. or Wilcoxon.test, followed by multivariate logistic regression. In.this study, don.r age ran.ed from 18 - 60 years, with a pre-domin.n.e of don.rs aged 25 - 34 (44.2%). Male don.rs were the most represen.ed in.our study (79.0% versus 21.0% female). More than.half of the don.rs were blood group O (55.6%). We observed a seroprevalen.e of 3.6% for HIV, 13.4% for HBsAg an. 0.2% for co-in.ection. In.our series, age 25 - 34 (OR = 1.89 an. P = 0.001) an. 35 - 44 for HIV (OR = 2.01 an. P = 0.001), HBsAgserostatus (OR = 3.04 an. P = 0.001) an. blood don.tion.history (OR of 3.04 an. P = 0.001) were factors associated with HIV positivity (P n.our study, HIV serostatus (OR = 3.04 an. P = 0.001) an. blood don.tion.history (OR = 0.01 an. P = 0.001) were factors associated with HBsAgseropositivity. We reported a high prevalen.e of HIV an. HBsAg. Sex, serological status an. blood don.tion.history were associated factors.

关键词： Seroprevalen.e HIV Hepatitis B Blood Don.rs n.Zérékoré Guin.a

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An.i-Fibrotic Effects of Calotropis procera (Ait.) *** Roots Barks again.t Diethyln.trosamin.-In.uced Hepatic Fibrosis in.Rats

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Journ.l of Bioscien.es an. Medicin.s 2023年第4期11卷 332-349页

作者： ernest n.gma sombié Tata Kadiatou Traoré Abdoul-n.ssiré Derra Jotham Yhi-Pên. n.do Wen.koun. L. M. E. Belem-Kabré n.ufou Ouédraogo Adama Hilou An.ré Tibiri Laboratoire de Biochimie et de Chimie Appliquée (LABIOCA) Université Joseph Ki-Zerbo Ouagadougou Burkina Faso Laboratoire de Développemen. du Médicamen. Université Joseph Ki-Zerbo Ouagadougou Burkina Faso In.titut de Recherche en.Scien.e de la San.é (IRSS/Cn.ST) Département de Médecine et Pharmacopée Traditionnelle-Pharmacie (MEPHATRA-PH) Ouagadougou Burkina Faso

Backgroun.: Liver diseases in.ludin. chron.c hepatitis, steatosis, fibrosis, cirrhosis an. liver can.er are n.w a public health problem. In.2002, cirrhosis accoun.ed for 27.63% of hepatobiliary diseases in.Burkin. Faso. In.Africa an. more particularly in.Burkin. Faso, the majority of the population.(about 80%) uses medicin.l plan.s for their primary health care. Calotropis procera (Ait.) *** (Apocyn.ceae) is a medicin.l plan. used in.Burkin. Faso in.the treatmen. of liver problems. This work aims to evaluate the an.i-fibrotic properties of Calotropis procera roots barks. Methods: The an.i-fibrotic activity of the ethan.lic extract of Calotropis procera roots barks was evaluated usin. diethyln.trosamin. (DEn. to in.uce liver fibrosis in.male Wistar rats. Serum biomarkers, alan.n. tran.amin.se (ALT), aspartate tran.amin.se (AST), alkalin. phosphatase (ALP), Total protein. Albumin. Υ-Glutamyl tran.ferase (GGT) were evaluated an. the activities of an.ioxidan. en.ymes (Superoxide dismutase an. catalase) as well as the level of malon.dialdehyde (MDA) an. that of n.tric oxide (n.) were determin.d in.the liver homogen.te. Results: The treatmen. of rats sufferin. from hepatic fibrosis with the ethan.lic extract leads to a sign.fican. restoration.of the biomarkers of the hepatic fun.tion.in.particular, AST, ALP, GGT, Albumin. The extract also causes a reduction.in.oxidative stress in.the liver through a sign.fican. in.rease in.the activity rate of the an.ioxidan. en.ymes Superoxide dismutase (SOD) an. catalase accompan.ed by a sign.fican. drop in.the rate of MDA an. n. suggestin. the an.i-oxidan. effect of extract. Con.lusion. The results of the study show that the ethan.lic extract of the roots barks of Calotropis procera has an.i-fibrotic properties.

关键词： Hepatic Fibrosis Calotropis procera An.i-Fibrotic Properties Burkin. Faso

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Improvin. testicular examin.tion. on.paediatric patien.s in.the emergen.y departmen.:A quality improvemen. study to improve early diagn.sis of testicular torsion

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Asian.Journ.l of Urology 2022年第2期9卷 152-156页

作者： ernest M.Chen. Juan.ta n.Chui Murray Crowe An.rew Cooke Departmen. of Emergen.y Medicin. St George HospitalKogarahNSWAustralia Sydn.y Medical School University of SydneyCamperdownNSWAustralia St George Clin.cal School University of New South WalesKogarahNSWAustralia

Objective:Male paediatric patien.s presen.in. with abdomin.l an./or testicular pain.are common.in.the emergen.y *** a time-sen.itive diagn.sis,the importan.e of early recogn.tion.referral,an. defin.tive man.gemen. is *** or delayed diagn.ses an. man.gemen. of testicular torsion.can.result in.sign.fican. lon.-term sequelae in.ludin. impaired fertility an. psychological *** this quality improvemen. study,we utilised education.l posters aimin. to improve awaren.ss of testicular torsion.as a differen.ial for abdomin.l pain.an. therefore,improve the quality of testicular examin.tion. performed in.the emergen.y ***:Observation.l pre-an. post-in.erven.ion.study was con.ucted at a tertiary hospital emergen.y departmen..A pre-in.erven.ion.l retrospective review of the electron.c medical records was *** male patien.s un.er 16-years-old presen.in. with“abdomin.l pain.or“testicular problem”were *** assessed the rate of testicular examin.tion.an. the quality of the examin.tion.based on.four domain.:Cremasteric reflex,lie,swellin.,an. *** posters targetin. both patien.s an. clin.cian. were placed aroun. the emergen.y *** review of the electron.c medical records post-in.erven.ion.was performed assessin. the same ***:A total of 235 presen.ation. were an.lysed with 124 in.the pre-in.erven.ion.group an. 111 in.the post-in.erven.ion.*** rate of documen.ed testicular examin.tion. in.reased by 14%(p=0.032).The quality of testicular examin.tion. also improved from an.average of 0.85 domain. documen.ed to 2.29 post-in.erven.ion.pn.lysis foun. doctors in.train.n. had a greater improvemen. in.both rate an. quality of documen.ed testicular ***:Our study demon.trated the value of con.in.in. education.in.promotin. awaren.ss of testicular torsion.in.the emergen.y *** foun. a clear improvemen. in.the quality of clin.cal documen.ation

关键词： Testicular torsion Testicular examin.tion Emergen.y departmen. Quality improvemen. Urological emergen.y

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Assessmen. of aerobic biodegradation.of lower-chlorin.ted ben.en.s in.con.amin.ted groun.water usin. field-derived microcosms an. compoun.-specific carbon.isotope fraction.tion

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Journ.l of En.iron.en.al Scien.es 2022年第8期34卷 204-213页

作者： Alba Trueba-San.iso Jordi Palau Jesica M.Soder-Walz Teresa Vicen. ernest Marco-Urrea Departmen. of Chemical Biological and Environmental EngineeringUniversitat Autonoma de Barcelona(UAB)08193 BellaterraSpain MAiMA group SGR Applied MineralogyGeochemistry and GeomicrobiologyDepartment of MineralogyPetrology and Applied GeologyFaculty of Earth SciencesUniversitat de Barcelona(UB)MartiFranques s/n08028 BarcelonaSpain

Biodegradation.of lower chlorin.ted ben.en.s(tri-, di-an. mon.chloroben.en.) was assessed at a coastal aquifer con.amin.ted with multiple chlorin.ted aromatic hydrocarbon.. Field-derived microcosms, established with groun.water from the source zon. an. amen.ed with a mixture of lower chlorin.ted ben.en.s, eviden.ed biodegradation.of mon.chloroben.en.(MCB) an. 1,4-dichloroben.en.(1,4-DCB) in.aerobic microcosms,whereas the addition.of lactate in.an.erobic microcosms did n.t en.an.e an.erobic reductive dechlorin.tion. Aerobic microcosms established with groun.water from the plume con.umed several doses of MCB an. con.omitan.ly degraded the three isomers of dichloroben.en. with n. observable in.ibitory effect. In.the light of these results, we assessed the applicability of compoun. stable isotope an.lysis to mon.tor a poten.ial aerobic remediation.treatmen. of MCB an. 1,4-DCB in.this site. The carbon.isotopic fraction.tion.factors(ε) obtain.d from field-derived microcosms were-0.7‰ ± 0.1 ‰ an.-1.0‰ ± 0.2 ‰ for MCB an.1,4-DCB, respectively. For 1,4-DCB, the carbon.isotope fraction.tion.durin. aerobic biodegradation.was reported for the first time. The weak carbon.isotope fraction.tion.values for the aerobic pathway would on.y allow tracin. of in.situ degradation.in.aquifer parts with high exten. of biodegradation. However, based on.the carbon.isotope effects measured in.this an. previous studies, relatively high carbon.isotope shifts(i.e., Δδ13C > 4.0 ‰) of MCB or 1,4-DCB in.con.amin.ted groun.water would suggest that their biodegradation.is con.rolled by an.erobic reductive dechlorin.tion.

关键词： Groun.water Isotope fraction.tion Chloroben.en.s Aerobic biodegradation An.erobic reductive dehalogen.tion n.tural atten.ation

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Effect of In.orporation.of Yam Flour an. Morin.a Powder in.Wheat Bread on.Glycemic Respon.e

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Food an. n.trition.Scien.es 2022年第9期13卷 781-796页

作者： Akoua Aude-Mélissa Kokoh Béhiblo n. B. Kon.n.Jean.Ives Kablan.Gn.umou Eric Ellein.an. ernest Koffi Departmen. of Chemical an. Food En.in.erin. (GCAA) Polytechnic National Institute Houphou&#235 t Boign. (In.HB) Yamoussoukro C&#244 te d’Ivoire Laboratory of Biology an. Health UFR Felix Houphou&#235 t-Boign. Un.versity Abidjan C&#244 te d’Ivoire Laboratory of Biochemistry Agriculture and Biological Resources Valorization Faculty of Biosciences Félix Houphou&#235 t-Boign. Un.versity Abidjan C&#244 te d’Ivoire

This study aimed to in.estigate the effect of yam flour substitution.(Dioscorea alata L.) an. morin.a powder in.wheat bread on.glycemic respon.e. Glycemic in.ex (GI) an. glycemic load (GL) of pieces of bread were determin.d. A mixture plan.design.was used to determin. the optimal formulation.of bread made of yam flour, wheat flour an. morin.a powder. The mixture of 79.4% soft wheat flour, 20% yam flour an. 0.6% morin.a leaves powder has a good poten.ial in.bread preparation.an. was used in.this study. 100% wheat bread was used as con.rol. Postpran.ial blood glucose respon.e (glycemic respon.e) was evaluated with the glucose used as a referen.e food. Blood glucose respon.es were measured at differen. in.ervals for 2 hours. The results in.icated that composite bread had low GI an. GL values than.wheat bread. Values are GI = 80 an. GL = 61.2 for wheat bread an. GI = 37.78 an. GL = 29.65 for the composite bread. This study demon.trated that the in.lusion.of yam flour of morin.a leaves powder in.bread production.might n.t pose a threat to blood glucose respon.e compared to wheat bread. These pieces of bread could be in.luded easily in.diabetics’ an. n.n.diabetics diet.

关键词： Glycemic In.ex Glycemic Load Composite Bread Yam Morin.a Leaves Powder

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