检索结果-南通市图书馆

An update on hormonal regulation of early embryo-fallopian tube interactions: insights for improvements of assisted reproductive technology outcomes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reproductive and Developmental Medicine 2024年第1期8卷 39-49页

作者： Suranga P.Kodithuwakku ernest H.Y.Ng William S.B.Yeung Kai-fai Lee Department of Obstetrics and Gynaecology LKS Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China Department of Animal Science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka Shenzhen Key Laboratory of fertility Regulation.The University of Hong Kong-Shenzhen Hospital Shenzhen 518053China

Human fallopian tubes(fTs)play important roles in the whole reproductive *** are the site for the final maturation of gametes,fertilization,transport of preimplantation embryos,and early embryonic development before entering the *** these functions are critical in the establishment of a successful *** the embryo is in transit through the fT,the fT microenvironment changes through endocrine,paracrine,autocrine,and juxtacrine mechanisms which involve various hormones and bioactive substances mainly from the neighboring ***,the interactions between the embryo and the fT may be the earliest embryo-maternal communications that are essential for the establishment of *** review critically discusses the evidence of various hormonal and bioactive mediated control of the microenvironment in the fTs during the earliest embryo-maternal ***,we highlight existing gaps in the knowledge and the importance of exploring more of the physiology of fTs which will hold the key to producing high-quality embryos for patients seekingin vitro fertilization(IVf)treatments.

关键词： fallopian tube Embryo Maternal-embryo communication Hormonal control

Antibiotic Resistance Profile of Salmonella Strains Isolated at the National Clinical Biology and Public Health Laboratory in Bangui, Central African Republic

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Health 2024年第2期16卷 160-171页

作者： Marceline Djeintote ernest Lango-Yaya Zéphirin-Dalengat Vogbia Clotaire Donatien Rafaï Augustin Balekouzou Henri Saint-Claver Djemer Wilfried Sylvain Nambei Boniface Koffi Gérard Gresenguet National Blood Transfusion Center Bangui Central African Republic faculty of Health Sciences University of Bangui Bangui Central African Republic National Laboratory of Clinical Biology and Public Health Bangui Central African Republic National Reference Center for Sexually Transmitted Infections and Anti-Retroviral Therapy Bangui Central African Republic National Center for the fight against AIDS Bangui Central African Republic

In Africa, each year, there are estimated to be more than 91 million cases of salmonellosis and 137,000 cases of death. The problem of antibiotic resistance in Salmonella strains is a threat to public health. The objective of this study is to evaluate the antibiotic resistance profile of Salmonella strains isolated in biological products analyzed at the National Laboratory of Clinical Biology and Public Health (NLCBPH) in Bangui. This is, therefore, a cross-sectional study with a descriptive aim, running from January to December 2022. It focused on the strains of Salmonella isolated and identified in stools, urines, and blood samples. for each strain of Salmonella isolated, an antibiogram was carried out following the recommendations of the french Society of Microbiology (CASfM, 2022). A total of 93 strains of Salmonella have been recorded. The age group 0 - 9 years was 29% and that of >50 years was 11%. The median age of patients was 30 years with a minimum of 1 and a maximum of 78 years. The female gender was more represented at 52.69% than the male gender at 47.31%, i.e. a sex ratio of 0.89 (M/f). Salmonella strains were much more isolated in stools at 62% followed by urines at 29% and blood at 6%. Salmonella arizonae strains were more represented with 52%. Salmonella strains have a resistance rate to Tetracycline of 62.37% followed by Penicillins of 50%. The rate of multi-antibiotic resistance of the Salmonella strains isolated represented 48.38%. Salmonella spp. strains were multi-resistant at 58.69% followed by Salmonella arizonae strains at 47.91%. There is a significant association between the different families of antibiotics and Salmonella strains (p f resistance on Salmonella strains. No strain-producing Broad Spectrum Beta-lactamase has been isolated. Salmonella strains represent a zoonotic health danger, constitute a public health problem and remain a curre

关键词： Salmonella Resistance Antibiotics Central African Republic

Multiomics approaches to uncover endometrial receptivity in embryo implantation:a mini-review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reproductive and Developmental Medicine 2024年第3期8卷 178-185页

作者： Sudini R.fernando Yang Yan Manish Kumar Hoi-Lam Lai Yin-Lau Lee ernest H.Y.Ng William S.B.Yeung Kai-fai Lee Department of Obstetrics and Gynaecology Li Ka Shing Faculty of MedicineThe University of Hong KongPokfulamHong Kong SAR 999077China Department of Animal Science Faculty of Animal Science and Export AgricultureUva Wellassa UniversityBadullaSri Lanka Shenzhen Key Laboratory of fertility Regulation The University of Hong Kong-Shenzhen HospitalFutian DistrictShenzhen 518053China

Successful implantation requires concerted interactions during the apposition,adhesion,and invasion of the embryo into a receptive ***,the embryo implantation rate for assisted reproduction remains low despite the transfer of good quality *** in endometrial transcriptomics,proteomics,lipidomics,and even microbiota all play important roles in embryo ***,the expression of steroid hormone-regulated adhesive and anti-adhesive molecules during the embryo implantation window is becoming an area of increasingly intense *** review(a)summarizes the different molecules expressed in the receptive endometrium and(b)proposes the use of surface protein markers to predict pregnancy outcomes from assisted reproduction.

关键词： Cell surface proteins Steroid regulation Endometrial receptivity Receptivity marker Infertility

Effects of the substitution of cow’s milk with soymilk on the micronutrients,microbial,and sensory qualities of yoghurt

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

food Production, Processing and Nutrition 2022年第1期4卷 162-171页

作者： Dupe T.Otolowo Omolola M.Omosebi Kudirat T.Araoye Temiloluwa E.ernest Oluwatooyin f.Osundahunsi Department of food Science and Technology Mountain Top UniversityPrayer CityNigeria Department of food Science and Technology Wesley University OndoOndoNigeria Department of food Science and Technology Federal University of Oye-EkitiOye-EkitiNigeria Department of food Science and Technology Federal University of TechnologyAkureNigeria

The consumption of imported dairy products is high especially in developing countries including Nigeria where little or no milk is produced locally which makes the products expensive,out of reach to common consumers and also inconvenient for lactose intolerance and ***,as plant-based milk was substituted for cow’s milk in parts and in whole for the production of yoghurt and the effect of substitution was evaluated on the minerals,vitamins,microbial,and sensory properties of the products using the established *** differences(pf 0.14–28.50 mg/100 g and vitamin contents(ranged 0.02–0.43 mg/100 g)that were of comparable range of values with the yoghurt made with 100%cow’s milk(0.21–29.60 mg/100 g minerals and 0.05–0.58 mg/100 g vitamins).Generally,no significant difference(pf the sensory attributes evaluated(range 8.00–8.01)in the entire samples(except in the 100%soymilk yoghurt).The microbial analysis proved the safety of the entire products for *** showed the positive effect of substituting soymilk for cow’s milk at all the levels used,thus,the lactose intolerance and vegans can find alternative to dairy yoghurt in the 100%soymilk substitution and enjoy the functional health benefits of ***,the total dependence on importation of dairy milk and cost of production of composited milk yoghurt could be reduced to improve the nation’s economy and make the product economically accessible to common man.

关键词： Cow’s milk Soymilk Yoghurt Mineral and vitamin contents Microbial quality Sensory acceptability

Early stage risk communication and community engagement(RCCE)strategies and measures against the coronavirus disease 2019(COVID-19)pandemic crisi

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Global Health Journal 2021年第1期5卷 44-50页

作者： ernest Tambo Ingrid C.Djuikoue Gildas K.Tazemda Michael f.fotsing Xiao-Nong Zhou Higher Institute of Health Sciences University of the MountainsP.O.Box 208 BagangtéCameroon Prevention and Control NGOCameroon National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention

Coronavirus disease 2019(COVID-19)pandemic has proven to be tenacious and shows that the global commu nity is still poorly prepared to handling such emerging *** global solidarity in emergency preparedness and response,and the mobilization of conscience and cooperation,can serve as an excellent source of ideas and measures in a timely *** article provides an overview of the key components of risk communication and community engagement(RCCE)strategies at the early stages in vulnerable nations and populations,and highlight contextual recommendations for strengthening coordinated and sustainable RCCE preventive and emergency response strategies against COVID-19 *** solidarity calls for firming govemance,abundant community participation and enough trust to boost early pandemic preparedness and *** public RCCE response interventions needs crucially improving government health systems and security proactiveness,community to individual confinement,trust and resilience *** better understand population risk and vulnerability,as well as COVID-19 transmission dynamics,it is important to build intelligent systems for monitoring isolation/quarantine and tracking by use of artificial intelligence and machine learning systems *** and lessons learned from the international community is crucial for emerging pandemics prevention and control programs,especially in promoting evidence-based decision-making,integrating data and models to inform effective and sustainable RCCE strategies,such as local and global safe and effective COVID-19 vaccines and mass immunization programs.

关键词： Coronavirus disease 2019(COVID-19) Risk communication and communityengagement(RCCE) Response Trust Governance Pandemic Vaccination

Mass Screening Using Antigenic and Molecular Diagnostic Tests of COVID-19 in Bangui at the Beginning of the Second Wave in July 2021

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Tuberculosis Research 2024年第1期12卷 1-12页

作者： Clotaire Donatien Rafaï Marie-Roseline Darnycka Belizaire Pierre Somse Wilfrid Sylvain Nambei ernest Lango-Yaya Oscar Senzongo Luc Salva Hereidebona Ulrich Jeffrey Kotemossoua Rabbi Mermoz Senekian Simon Pounguinza Christian-Diamant Mossoro-Kpinde Alain Le faou Jean De Dieu Longo françois-Xavier Mbopi-Keou Gérard Grésenguet Boniface Koffi National Laboratory of Clinical Biology and Public Health Bangui Central African Republic faculty of Health Sciences University of Bangui Bangui Central African Republic World Health Organization Bangui Central African Republic Ministry of Health and Population Bangui Central African Republic faculty of Medicine Maieutic and Health Sciences University of Lorraine Pole Brabois Santé Nancy France faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroun

Objective: COVID-19 surveillance was established as early as March 2020 in the Central African Republic (CAR), after the WHO statement relating to the identification of several cases outside China. However, given the non-performing molecular biology technical platform in many developing countries in sub-Saharan Africa, the second wave promised to be surprising and formidable. In this context, a mass survey was launched in Bangui to determine the prevalence of COVID-19. Patients and Methods: from March 18 to April 2, 2021, a mass screening campaign took place in tourist places, companies and the main hospital infrastructures. Nasopharyngeal swab samples were collected from participants with and without symptoms of Influenza-like illness (ILI) and stored in VTM tubes. The Ag (COVID-19) and RT-PCR tests were carried out in Bangui at the LNBCSP. The sequencing of RT-PCR SARS-CoV-2 positives was carried out at the INRB. Results: We included 1480 participants of whom 33 (2.23%) were SARS-COV-2 positive, of whom 24 were male and 9 female. This sex difference was statistically significant (p = 0.012) as the sex ratio M/f was 1.09. Sampling sites located in the 1st arrondissement were the most prolific (p = 0.006) and were sequenced. In addition to the analysis of the 33 samples from the predefined sites under study, 17 control sequences from the provinces generated during the same period are added. We detected 2 Variants Of Concern (VOC) including the predominant B.1.620 (43.86%) followed by B.1.1.7 or Alpha (5.10%). Conclusion: The study showed the importance of surveillance and the availability of means of diagnosis of COVID-19. The identified risk factors were sex and sampling site. This study has shown the importance of setting up sentinel sites for COVID-19 surveillance in all regions of the country and the appropriate use of the anti-COVID-19 vaccine.

关键词： COVID-19 Variants Central African Republic

Seasonal variation for the antidiabetic activity of Loranthus micranthus methanol extract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2010年第3期3卷 196-199页

作者： Patience Ogoamaka Osadebe Edwin Ogechukwu Omeje Philip felix Uzor ernest Kenechukwu David Damian Chiedozie Obiorah Department of Pharmaceutical and Medicinal Chemistry Faculty of Pharmaceutical SciencesUniversity of Nigeria

Objective:To determine the season in which the Eastern Nigeria mistletoe,Loranthus micranthus,parasitic on Persea americana possesses optimum antidiabetic activity and to determine the seasonal variation in the ***:The antidiabetic activities of the aqueous methanol extracts of the leaves of Eastern Nigeria mistletoe,Loranthus micranthus, harvested in two seasons of the year,the onset of rainy season(April) and the peak of rainy season(July) were *** tests were carried out on six(6) groups(A-f) of alloxaninduced diabetic *** A and B received 200 mg/kg and 400 mg/kg of the April sample extracts respectively while groups C and D received same doses of the July sample extracts. Group E and f which were the positive and negative controls received 10 mg/kg of glibenclamide and 2 ml/kg of 3%tween 20 *** blood glucose levels of the animals were monitored hourly with a glucometer for six *** phytochemical analysis of the plant extracts were also carried out by standard ***:The results showed that group A and B exhibited significant(Pfasting blood sugar(fBS) level of the animals(38.9%and 39.2%respectively) with maximum reduction observed at the 5th and 6th hour respectively compared to glibenclamide(71.3%).Group C showed no significant (P>0.05) fBS reduction(15.9%) while group D exhibited highly significant(Pfter 6 *** phytochemical analysis of the crude methanol extracts revealed the presence of carbohydrates,glycosides,saponins, tannins,flavonoids,steroids,terpenoids,acidic compounds,resins and *** were present in different proportions in both ***:This study shows that there is a seasonal, dose-dependent variation in the chemical composition viz-a-viz the antidiabetic activity of the plant under *** activity is highest at the peak of the rainy season.

关键词： Antidiabetic activity Loranthus micranthus Methanol extract Phytochemical analysis Seasonal variation

Assessing the prevalence of urogenital schistosomaisis and transmission risk factors amongst school-aged children around Mapedam ecological suburbs in Malantouen district,Cameroon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2017年第1期6卷 360-367页

作者： Adeline P.Mewabo Roger S.Moyou Lysette E.Kouemeni Jeanne Y.Ngogang Lazare Kaptue ernest Tambo Department Biochemistry Higher Institute of Health SciencesUniversitedes MontagnesBangangteCameroon Institut de Recherches Medicales et d’Etudes des Plantes Medicinale-Centre de Recherches Medicales(IMPM-CRM) YaoundeCameroon Africa Disease Intelligence and Surveillance Communication and Response(Africa DISCoR)InstituteYaoundeCameroon

Background:Urogenital schistosomiasis is a parasitic infection of public health importance that affects over 112 million people *** study aimed at assessing the urogenital schistosomiasis prevalence and risk factors of transmission around Mape dam suburds in Malantouen district,West,***:The study was conducted using semi-structured pretested questionnaires to collect socio-demographic and ecological *** samples were also collected and used to confirm the prevalence of schistosomiasis in consented school-aged children in four primary schools between March-July ***’samples around the dam surburbs were also collected for taxonomy characterization and species *** were compiled and quality control assessed and analysed using SPSS version 17 and Epiinfo data 3.1.Pf 1.04(m/f).The prevalence of schistosomiasis haematobium was 16.6%.Mambonko school site,which is the closest to the dam suburbs,registered the greatest prevalence rate of 40%.The age group beween 10-13 years was the most infected(18.3%)and boys were more infested than girls(21.0%vs.15.5%).Haematuria,urination pain,school absentiesm and poor performance were the major recorded complications in 39.5 and 26.3%males to female *** rate gender disparity documented is still poorly understood and Bulinus truncatus collected from Mambonko suburb as potential snail intermediate host requires further ***:Authors advocated that schools and dam suburds sustained and innovative community-based surveillance and response targeted interventions implementation are needed to inform and support decisionmaking policy,but also in improving effective contextual behavioural communication changes and MDA improved uptake measures on national schistosomiasis control and elimination in Cameroon.

关键词： Urogenital schistosomiasis Pupils Schistosoma haematobium Prevalence Risk factors Mape dam

Assessment of Mercury (Hg) and Cyanide (CN) Pollution in Surfacewaters, Groundwaters and Sediments around Industrial Mining Sites in the Department of Divo (Ivory Coast)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Water Resource and Protection 2021年第2期13卷 75-91页

作者： Yao Kouassi Serge Aristide Ahoussi Kouassi ernest Training and Research Unit for Earth Sciences and Mining Resources Soil Water and Geomaterials Laboratory Université Félix Houphou&euml t-Boigny Abidjan Ivory Coast

Contamination of water and sediments by trace metal elements constitutes a risk to water, living species and for human health. The objective of this study is to assess the level of contamination of water and sediments in the Divo mining area with trace elements. Trace elements (CN and Hg) were determined in water and sediments using an Inductive Coupled Plasma Atomic Emission Spectrometer (ICP-AES). The intensity of sediment contamination was estimated from the calculation of several indices, including the Contamination factor (fC), the Modified Contamination Degree (DCm) and the Sediment Pollution Index (SPI). The results of the monitoring of the seasonal evolution of TME (CN and Hg), during the months of September 2018 and february 2020 are as follows: In surface water, the metallic concentrations vary from 0 to 4. 98 μg/L for mercury and 0 to 95 μg/l for cyanide. All surface water samples have mercury concentrations lower than the average reference concentration of 6 μg/L. 7% of surface water samples have cyanide concentrations above the average concentration of 70 μg/L. Concerning groundwater, the cyanide concentrations remained below the standards for drinking water over the two seasons. Mercury recorded high concentrations in wells in the department. The sediments were found to be polluted with CN (uncontaminated to low contamination/very heavily contaminated) and Hg (uncontaminated to moderately contaminated/very heavily contaminated). The IPS values show that the surface sediments are moderately polluted except at the HR6 stations (0.07);ZR3 (0.22);AR1 (1.15);R3 (0.96);BRR (0);DRV (0.07) where the sediments are healthy. The inhabitants of mining areas are exposed to the risk of contracting various diseases by consuming this water contaminated with these trace elements.

关键词： Mercury Cyanide Sediments Contamination Source Apportionment