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Role of molecular imaging in the management of patients affected by inflammatory bowel disease:State-of-the-art

World Journal of Radiology 2016年第10期8卷 829-845页

作者： Federico Caobelli Laura Evangelista Natale Quartuccio Demetrio Familiari Corinna Altini Angelo Castello Mariapaola Cucinotta Rossella Di Dato Cristina Ferrari Aurora Kokomani Iashar Laghai Riccardo Laudicella Silvia Migliari Federica Orsini Salvatore Antonio Pignata Cristina Popescu erinda puta Martina Ricci Silvia Seghezzi Alessandro Sindoni Martina Sollini Letterio Sturiale Anna Svyridenka Vittoria Vergura Pierpaolo Alongi Department of Nuclear Medicine Universitatsspital Basel Department of Nuclear Medicine Istituto Oncologico Veneto Wolfson Molecular Imaging Centre Univer-sity of Manchester Department of Nuclear Medicine A.R.N.A.S. Nuclear Medicine Unit Univer-sity"Aldo Moro"of Bari Department of Nuclear Medicine University of Florence Department of medical-surgical science and translational medicine "La Sapienza"University Nuclear Medicine Unit Department of Biomedical Sciences and Morphological and Functional ImagesUniversity of Messina Department of Nuclear Medicine University of Parma Department of Nuclear Medicine University Hospital"Maggiore della Carita di Novara" Department of Nuclear Medicine Niguarda Ca'Grande Hospital Department of Nuclear Medicine Hospital of Treviglio Humanitas University Department of Nuclear Medicine University of Bologna Nuclear Medicine Unit Department of Radio-logical SciencesG.Giglio Institute

AIM To present the current state-of-the art of molecular imaging in the management of patients affected by inflammatory bowel disease(IBD).METHODS A systematic review of the literature was performed in order to find important original articles on the role of molecular imaging in the management of patients affected by IBD. The search was updated until February 2016 and limited to articles in *** Fifty-five original articles were included in this review, highlighting the role of single photon emission tomography and positron emission tomography. CONCLUSION To date, molecular imaging represents a useful tool to detect active disease in IBD. However, the available data need to be validated in prospective multicenter studies on larger patient samples.

关键词： White blood cell scintigraphy Inflammatory bowel disease Inflammation ^(18)F-Fluorodehoxiglucose positron emission tomography/computed tomography Molecular imaging

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