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读友 2021年第19期 122-124页

作者： Tae Keller Christina Soontornvat erin entrada kelly Carole Boston Weatherford 不详

桌子去年,我们为大家介绍了2020年的纽伯瑞儿童文学奖获奖作品,获得许多同学的关注。这期,我们为大家介绍2021年的纽伯瑞儿童文学奖获奖作品。

关键词：书虫纽伯瑞儿童文学奖获奖作品

The Groovy Lifestyles of New Millennium

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英语学习 2000年第1期 10-11页

作者： erin kelly 绿野

Bill Lord isn’t waiting for the new millennium tostart doing his part to protect the ***61-year-old college professor and retired TV journalistis using today’s technology to make a difference *** Lord retired from h... 详细信息

关键词： The Groovy Lifestyles of New Millennium

New“green revolution”cleaner cars and energy

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英语学习 2000年第2期 16-17页

作者：钟灵 erin kelly

By 2010,you may be driving apollution-free,recyclable car,eating genetically engineered foodgrown without pesticides,avoidingrush-hour traffic jams by working andshopping at your home computer,andlighting your home wi... 详细信息

关键词：燃料电池 green revolution New cleaner cars and energy

Predicting the dynamics of local adaptation in invasive species

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Journal of Arid Land 2013年第3期5卷 268-274页

作者： erin K ESPELAND USDA-ARS Pest Management Research Unit Sidney MT 59270USA

An invasive plant species may restrict its spread to only one type of habitat, or, after some time, may continue to spread into a different, often stressful, secondary, habitat. The question of whether evolution is required for an invasive species to spread from one habitat to another is currently hotly debated. In order for local adaptation to occur, genetic variation must be present within invasive populations. In this paper, I focus on the effect of habitat on the maintenance of genetic variation during the lag phase, the phase of population stability prior to expansion. Genetic diversity in invasive plant populations accumulates through multiple introductions, gene flow, mutation, and hybridization, but diversity is maintained by population level processes influencing effective population size （Ne）. I show that when the plastic response to the environment results in little variation in reproductive output among indi- viduals, Ne is maximized and genetic variation is maintained. Established models of plant competition show that below-ground competition reduces the variation in reproductive output, whereas competition for light increases variation in reproductive output. The same environments that maintain high Ne also reduce the opportunity for se- lection and minimize the response to selection, and thus the effects of the environment are synchronized to prevent genetic purges. When the primary invasion habitat supports high Ne, conditions are ripe for local adaptation to a secondary habitat, particularly if the secondary habitat has high opportunity for selection. When the primary invasion habitat supports low Ne, genetic diversity is less likely to be sufficient for local adaptation to secondary habitat to occur.

关键词： canalization phenotypic plasticity population expansion secondary invasion

Structure-aware fusion network for 3D scene understanding

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Chinese Journal of Aeronautics 2022年第5期35卷 194-203页

作者： Haibin YAN Yating LV Venice erin LIONG School of Automation Beijing University of Posts and TelecommunicationsBeijing 100876China Interdisciplinary Graduate School Nanyang Technological UniversitySingapore 639798Singapore

In this paper,we propose a Structure-Aware Fusion Network(SAFNet)for 3D scene *** 2D images present more detailed information while 3D point clouds convey more geometric information,fusing the two complementary data can improve the discriminative ability of the *** is a very challenging task since 2D and 3D data are essentially different and show different *** existing methods first extract 2D multi-view image features and then aggregate them into sparse 3D point clouds and achieve superior ***,the existing methods ignore the structural relations between pixels and point clouds and directly fuse the two modals of data without *** address this,we propose a structural deep metric learning method on pixels and points to explore the relations and further utilize them to adaptively map the images and point clouds into a common canonical space for *** experiments on the widely used ScanNetV2 and S3DIS datasets verify the performance of the proposed SAFNet.

关键词： 3D point clouds Data fusion Structure-aware 3D scene understanding Deep metric learning

Current and emerging therapies in unresectable and recurrent gastric cancer

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World Journal of Gastroenterology 2016年第20期22卷 4812-4823页

作者： erin Jou Lakshmi Rajdev Department of Oncology Montefiore Medical Center/Albert Einstein College of Medicine

Gastric cancer is one of the most lethal cancers worldwide despite many advances and options in therapy. As it is often diagnosed at an advanced stage, prognosis is poor with a median overall survival of less than twelve months. Chemotherapy remains the mainstay of treatment for these patients but it confersonly a moderate survival advantage. There remains a need for new targeted treatment options and a way to better define patient populations who will benefit from these agents. In the past few years, there has been a better understanding of the biology, molecular profiling, and heterogeneity of gastric cancer. Our increased knowledge has led to the identification of gastric cancer subtypes and to the development of new targeted therapeutic agents. There are now two new targeted agents, trastuzumab and ramucirumab, that have recently been approved for the treatment of advanced and metastatic gastric cancer. There are also many other actively investigated targets, including epidermal growth factor receptor, the phosphatadylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathway, c-Met, poly ADP-ribose polymerase, and immune checkpoint inhibition. In this review, we discuss the current management of advanced gastric cancer as well as emerging targeted therapies and immunotherapy.

关键词： Advanced gastric cancer Immunotherapy Human epidermal growth factor receptor type 2 Targeted therapy Vascular endothelial growth factor receptor

Metabolic reprogramming of glial cells as a new target for central nervous system axon regeneration

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Neural Regeneration Research 2022年第5期17卷 997-998页

作者： erin L.Walden Shuxin Li Shriners Hospitals Pediatric Research Center Department of Neural SciencesLewis Katz School of Medicine at Temple UniversityPhiladelphiaPAUSA

After central nervous system(CNS)injury,severed axons fail to regenerate and their disconnections to the original targets result in permanent functional deficits in patients(Mahar and Cavalli,2018).Both the diminished intrinsic regenerative capacity of mature neurons and the inhibitory CNS milieu contribute to the regenerative failure following CNS injury.

关键词： programming system permanent

Focal seizure associated with human parvovirus B19 infection in a non-encephalopathic child

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World Journal of Pediatrics 2016年第1期12卷 118-120页

作者： Debopam Samanta erin Willis Division of Child Neurology University of Arkansas for Medical SciencesLittle RockArkansasUSA

Background:The incidence of acute symptomatic(at the time of documented brain insult)seizures and single unprovoked seizures are 29-39 and 23-61 per 100000 per year,*** stabilization of the patient,fi nding the etiology of the seizure is of paramount importance.A careful history and physical examination may allow a diagnosis without need for further ***:In the literature,severe central nervous system involvement has been reported from human parvovirus B19 *** reported a previously healthy 7-year-old girl who presented after an episode of focal *** was afebrile and didn't have any focal neurological *** had erythematous malar rash along with reticulating pattern of rash over her both upper ***:Parvovirus infection was suspected due to the characteristic erythematous malar *** human parvovirus B19 DNA polymerase chain reaction was positive which was consistent with acute parvovirus *** confirmation of current infection was done with Sandwich enzyme immunoassays showing positive anti-B19 IgM Index(>1.1).IgG index was equivocal(0.9-1.1).Conclusions:We report an extremely rare presentation of non-febrile seizure from acute parvovirus infection in a child without encephalopathy who had an excellent *** diagnosis can provide counselling regarding future seizure recurrence risk,curtail expenditure from expensive diagnostic work up and provide additional recommendations about potential risks to a pregnant caregiver.

关键词： erythema infectiosum human parvovirus B19 nonfebrile seizure

Neurotransmitter Modulation Relates with Tinnitus Signal Generation and Management

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Journal of Otology 2007年第2期2卷 63-69页

作者： erin Laundrie Center for Hearing and Deafness Department of Communicative Disorders and Sciences University at Buffalo Buffalo NY 14214 USA

Tinnitus is a subjective perception of phantom sound that currently cannot be objectively measured. However, there is growing evidence suggesting that the biological source of tinnitus may exist in one or more than one place in the auditory pathway. Recent studies have found that neurotransmitters or modulators, such as glutamate, γ-aminobutyric acid(GABA), serotonin, dynorphin, dopamine, neurosteroid, acetylcholine(ACh) and substance P, are involved in tinnitus generation. Animal and human studies have shown that some of these neurotransmitters and the agonists or antagonists of their receptors either affect tinnitus behaviors or demonstrate some degree of treatment effects on tinnitus. However, due to the unclear biological mechanisms of tinnitus and side effects of these drugs, the value of clinical usage of such drugs in treating tinnitus is yet to be established. Revealing the relationship between tinnitus and neurotransmitter receptor functions will help identify more effective drugs for tinnitus treatment. This article reviews the literature of neurophysiological studies on tinnitus in both animal and human subject studies at various levels of the auditory pathway.

关键词： tinnitus auditory system NMDA serotonin GABA ACh

Epidermal collagenase activity and its induction by 20-hydroxyecdysone in the fiddler crab Uca pugilator

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Current Zoology 2009年第1期55卷 75-80页

作者： erin A. TOUPS Enmin ZOU Department of Biological Sciences Nicholls State University

The epidermal collagenase activity and its induction by 20-hydroxyecdysone in Uca pugilator were investigated. Zymographic electrophoresis showed four bands of collagenase activity, 16, 19, 22 and 29 kDa in molecular weight, with the former two accounting for 60% and 36% , respectively, of the total collagenase activity. The collagenase activity varies during the molting cycle. Among the molt stages tested, Premolt Stage Do exhibited the highest epidermal collagenase activity for both the 16 and 19 kDa isoenzymes and, as the molt stage proceeded, the enzymatic activity of these two isoenzymes decreased, with the lowest activity for both found in Premolt Stage D3 -4 - Injection of 20-hydroxyecdysone significantly induced the activity of the 16 kDa eollagenase in the epidermis of Uca pugilator, suggesting that the activity of this isoenzyme is under molting hormone control. Although 20-hydroxyeedysone injection did not result in a statistically significant increase in the activity of the 19 kDa isoenzyme, a tendency of the induction was nonetheless demonstrated. This is the first report on epidermal collagenase activity and its induction by the molting hormone in a crustacean .

关键词： Collagenase Crustacean Epidermis Exoskeleton 20-Hydroxyecdysone Uca pugilator