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e-DNA scaffold sensors and the reagentless, single- s.e., measurement of HIV-diagnostic antibodies in human serum

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Microsys.e.s & Nanoengineering 2020年第1期6卷 1141-1148页

作者： Claudio Parolo Ava s.Greenwood Nathan e.Ogden Di Kang Chase Hawes Gabriel Ortega Netzahualcoyotl Arroyo-Curras Kevin W.Plaxco Department of Chemistry and Biochemistry University of CaliforniaSanta BarbaraSanta BarbaraCAUSA Department of Materials University of CaliforniaSanta BarbaraSanta BarbaraCAUSA Department of Pharmacology and Molecular sciences Johns Hopkins School of MedicineBaltimoreMD 21205USA Interdepartmental Program in Biomolecular science and engineering University of CaliforniaSanta BarbaraSanta BarbaraCA 93106USA

The multiplexed,point-of-care measurement of s.e.ific antibodies could improve the s.e.d with which diseases are diagnosed and their treatment *** this.e.d,we are developing e-DNA scaffold sensors,which consist of a rigid,nucleic acid“scaffold”attached on one end to an electrode and presenting both a redox reporter and an epitope on the *** the absence of antibody,the reporter efficiently trans.e.s.e.ectrons when interrogated ***-induced s.e.ic hindrance limits movement,reducing electron trans.e. in a manner that is both easily measured and quantitatively related to target *** we have used monoclonal antibodies to explore the analytical performance of e-DNA sensors,showing that they support the rapid,single-s.e.,quantitative detection of multiple antibodies in small volume ***,in contrast,we employ authentic human samples to better explore the platform’s clinical ***,we developed e-DNA sensors targeting three HIV-s.e.ific antibodies and then compared the analytical and clinical performance of these against those of gold standard serological *** so we find that,although the multis.e. amplification of an eLIsA leads to a lower detection limits,the clinical sensitivity of eLIsAs.e.DNA sensors and lateral-flow dipsticks are indistinguishable across our test *** thus appears that,by merging the quantitation and multiplexing of eLIsAs with the convenience and s.e.d of dipsticks.e.DNA scaffold sensors could significantly improve on current serological practice.

关键词： antibodies attached initiated

Melting heat trans.e. effects on stagnation point flow of micropolar fluid saturated in porous medium with internal heat generation(absorption)

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Applied Mathematics and Mechanics.e.glish edition) 2014年第8期35卷 979-992页

作者： M.A.A.MAHMOUD s.e.WAHeeD Department of Mathematics Faculty of ScienceBenha University 13518BenhaEgypt Department of Mathematics and statistic Faculty of ScienceTaif University 21974TaifKingdom of Saudi Arabia

The effect of melting heat trans.e. on the two dimensional boundary layer flow of a micropolar fluid near a stagnation point embedded in a porous medium in the presence of internal heat generation/absorption is investigated. The governing non-linear partial differential equations describing the problem are reduced to a sys.e. of non-linear ordinary differential equations using similarity transformations solved numerically using the Chebys.e. s.e.tral method. Numerical results for velocity, angular velocity and temperature profiles are shown graphically and discus.e. for different values of the inverse Darcy number, the heat generation/absorption parameter, and the melting parameter. The effects of the pertinent parameters on the local skin-friction coefficient, the wall couple stress, and the local Nus.e.t number are tabulated and discus.e.. The results show that the inverse Darcy number has the effect of enhancing both velocity and temperature and suppressing angular velocity. It is also found that the local skin-friction coefficient decreases, while the local Nus.e.t number increases as the melting parameter increases.

关键词： melting effect stagnation point micropolar fluid porous medium heat generation (absorption)

Variable fluid properties and thermal radiation effects on flow and heat trans.e. in micropolar fluid film past moving permeable infinite flat plate with slip velocity

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Applied Mathematics and Mechanics.e.glish edition) 2012年第5期33卷 663-678页

作者： M.A.A.MAHMOUD s.e.WAHeeD Department of Mathematics Faculty of ScienceBenha UniversityBenha 13518Egypt

This work deals with the influence of thermal radiation on the problem of the mixed convection thin film flow and heat trans.e. of a micropolar fluid past a moving infinite vertical porous flat plate with a slip velocity. The fluid viscosity and the thermal conductivity are assumed to be the functions of temperature. The equations governing the flow are solved numerically by the Chebys.e. s.e.tral method for some representative value of various parameters. In comparison with the previously publis.e. work, the excellent agreement is shown. The effects of various parameters on the velocity, the microrotation velocity, and the temperature profiles, as well as the skin-friction coefficient and the Nus.e.t number, are plotted and discus.e..

关键词： micropolar fluid thin film slip velocity variable fluid properties thermalradiation Chebys.e. s.e.tral method

The Mathematical Analysis for Peristaltic Flow of Hyperbolic Tangent Fluid in a Curved Channel

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Communications in Theoretical Physics 2013年第6期59卷 729-736页

作者： s.Nadeem e.N.Maraj Department of Mathematics Quaid-i-Azam University

In the present paper, we have investigated the peristaltic flow of hyperbolic tangent fluid in a curved channel. The governing equations of hyperbolic tangent fluid model for curved channel are derived including the effects of curvature. The highly nonlinear partial differential equations are simplified by using the wave frame transformation,long wave length and low Reynolds number assumptions. The reduced nonlinear partial differential equation is solved analytically with the help of homotopy perturbation method (HPM). The physical features of pertinent parameters have been discus.e. by plotting the graphs of pressure rise and stream functions.

关键词： tangent hyperbolic fluid curved channel peristaltic flow HPM

Bringing Norwegian mine into world of bits and bytes——possibilities and pitfalls

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中国有色金属学会会刊：英文版 2005年第S1期15卷 262-265页

作者： s. L. ellefmo e. Ludvigsen Department of Geology and Mineral Resources.e.gineering Norwegian University of Science and Technology NorwayDepartment of Geology and Mineral Resources Engineering Norwegian University of Science and Technology Norway

Rana Gruber As is a mining company situated in northern Norway, just south of the artic circle. The hematite/magnetite ore is low grade, s.e.ply dipping and intensively folded. The company excavates about 1.2 million tonnes of ore annually. The mining method is sublevel stoping. The final products are a hematite concentrate and different magnetite-products. The bits and bytes based methods and sys.e.s implemented for production planning and controlling are presented in the paper. Focus is on geological modelling, utilisation of variations in the deposit and associated uncertainty accumulating throughout the value chain. The methods and sys.e.s.e.able the mining department in greater extent than before, to deliver fragmented ore according to the s.e.ifications given by the processing plant.

关键词： mining geological variations uncertainty

极区电离层对IMF Bz4次快速转向的响应--eIsCAT／esR雷达观测

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地球物理学报 2009年第7期52卷 1685-1692页

作者：蔡红涛马淑英 I.W. McCrea J. A. Davi M. Lockwood s.e. Milan 武汉大学电子信息学院武汉430079 武汉大学空间环境与大地测量教育部重点实验室武汉430079 space science and Technique Department Rutherford Appleton Laboratory Chilton Oxfordshire OX11 0QX UK Department Physics and Astronomy University of Leicester UK

利用eIsCAT VHF和eIsCAT svalbard(esR)雷达观测数据,对2003年2月12日IMF B_z分量4次快速方向转换期间,极区电离层,尤其是极尖/极隙区的响应特征进行了分析研究.随着IMF B_z方向的多次快速变化,地面雷达观测到极尖/极隙区所在位置随着... 详细信息

利用eIsCAT VHF和eIsCAT svalbard(esR)雷达观测数据,对2003年2月12日IMF B_z分量4次快速方向转换期间,极区电离层,尤其是极尖/极隙区的响应特征进行了分析研究.随着IMF B_z方向的多次快速变化,地面雷达观测到极尖/极隙区所在位置随着开放闭合磁力线边界在纬度方向上来回移动.在此期间,极区电离层等离子体水平对流多次反向,表现出与IMF B_z分量强的负相关性.进一步分析表明:极区磁层-电离层系统在日侧对IMF极性变化的平均响应时间约为3 min.

关键词：极尖/极隙区行星际磁场 eIsCAT/esR雷达磁重联

Pulsed-Laser Annealing of NiTi shape Memory Alloy Thin Film

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Journal of Materials science & Technology 2009年第1期25卷 135-140页

作者： s.K. sadrnezhaad e. Rezvani s. sanjabi A.A. Ziaei Moayed Materials and energy Research Center P.O. Box 14155-4777 Tehran Iran Department of Materials science and engineering Sharif University of Technology P.O. Box 1156-9466 Tehran Iran Department of Materials science and engineering Tarbiat Modarres University P.O. Box 14115-143 Tehran Iran

Local annealing of amorphous NiTi thin films was performed by using an Nd：YAG 1064 nm wavelength pulsed laser beam. Raw samples produced by simultaneous sputter deposition from elemental Ni and Ti targets onto unheated si （100） and silica （111） substrates were used for annealing. Delicate treatment with 15.92 W/mm^2 power density resulted in crystallization of small spots; while 16.52 and 17.51 W/mm^2 power densities caused ablation of the amorphous layer. Optical microscopy, scanning electron microscopy, X-ray diffraction and atomic force microscopy were performed to characterize the microstructure and surface morphology of the amorphous/crystallized spot patterns.

关键词： Local heat treatment NiTi thin film Pulsed laser annealing Amorphous/crystallized spot composite

Genetic analysis of growth and wood variations in Leucaena leucocephala (Lam.) de Wit.

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Journal of Forestry Research 2013年第3期24卷 485-493页

作者： e K. Pande A. Kumar s. Ravichandran s. Naithani V. Kothiyal e B. K. Kishore A. Raturi e Gautam s. Dobhal s. sharma Forest Research Institute EO. IPE Dehradun 248195 India. Directorate of Rice Research Hyderabad India. Osmania University Hyderabad India

We selected 28 populations of Leucaena leucocephala from different geographical locations in the states of Andhra Pradesh, Tamil Nadu and Orissa of India on the basis of height and girth at breast height （GBH）. We evaluated fiber length, optical density, wall thickness, ves.e. element length, ves.e. element diameter, s.e.ific gravity and lignin of these populations of L. leucocephala in different sites. Populations had significant variations for all growth, wood and paper parameters. Girth at breast height （GBH） and s.e.ific gravity were the most important pa- rameters for heritability and genetic gain, res.e.tively. The minimum heritability was reported for ves.e. element length and genetic gain for fiber length. The populations were grouped into six clus.e.s, clus.e. II had maximum number of populations （14） and clus.e.s IV and VI had one population each. GBH contributed maximum of 34.39 % towards total divergence followed by s.e.ific gravity （14.02%）. An economic technique to produce quality s.e. by establishing s.e. orchards with genetically divergent parents was sugges.e.. The hybridization among the populations selected from diverse clus.e.s could produce greater heterosis needed for higher growth and suitable wood and paper manu- facturing parameters.

关键词： Leucaena leucocephala wood parameters heritability ge-netic advance s.e. orchards

A decision model for decentralized autonomous organization platform selection: Three industry case studies

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Blockchain(Research and Applications) 2023年第2期4卷 82-100页

作者： e.Baninemeh s.Farshidi s.Jansen Department of Information and Computer science Utrecht UniversityUtrechtthe Netherlands Department of software engineering Lappeenranta University of TechnologyLappeenrantaFinland

Context:Decentralized autonomous organizations are a new form of smart contract-based *** autonomous organization platforms,which support the creation of such organizations,are becoming increasingly popular,such as Aragon and *** the best fitting platform is challenging for organizations,as a significant number of decision criteria,such as popularity,developer availability,governance iss.e. and consis.e.t documentation of such platforms,should be ***,decision-makers at the organizations are not experts in every domain,so they must continuously acquire volatile knowledge regarding such ***:supporting decision-makers in selecting the right decentralized autonomous organization platforms by designing an effective decision model is the main objective of this *** aim to provide more insight into their selection process and reduce time and effort significantly by designing a decision ***:This study presents a decision model for the decentralized autonomous organization platform selection *** decision model captures knowledge regarding such platforms and concepts *** model is based on an existing theoretical framework that assists software engineers with a set of multi-criteria decision-making problems in software ***:We conducted three industry case studies in the context of three decentralized autonomous organizations to evaluate the effectiveness and efficiency of the decision model in assisting *** case study participants declared that the decision model provides significantly more insight into their selection process and reduces time and ***:We observe in the empirical evidence from the case studies that decision-makers can make more rational,efficient,and effective decisions with the decision ***,the reusable form of the captured knowledge regarding decentralized autonomous organization platforms can be

关键词： Decentralized autonomous organization Decision model Multi-criteria decision making Decision support sys.e. Decentralized autonomous organization platform Case study research