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Validity of self-reported male sexual function scales in a young Chinese population:a comparative study with clinician-assisted evaluation

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Asian Journal of Andrology 2024年第3期26卷 321-327页

作者： Hui Zhang Elena Colonnello erika Limoncin Tommaso B Jannini Xu-Chong Tu Andrea sansone Emmanuele A Jannini Yan Zhang Department of Infertility and sexual Medicine Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510000China Chair of Endocrinology and Medicalsexology(ENDOsEX) Department of Experimental MedicineUniversity of Rome Tor VergataRome 00133Italy Department of Urology First Affiliated Hospital ofGuangzhou University of Chinese MedicineGuangzhou 510000China section of Medical Pathophysiology Food Science and EndocrinologySapienza University of RomeRome 00133Italy school of Psychiatry Department of Systems MedicineUniversity of Rome Tor VergataRome 00133Italy

Psychometric scales,commonly used to gauge sexual function,can sometimes be influenced by response *** our researchfrom June 2020 to April 2021,we examined the accuracy of self-reported sexual function *** invited patients from theDepartment of Infertility and sexual Medicine at the Third Affiliated Hospital of sun Yat-sen University(Guangzhou,China),whohave male sexual dysfunction,to participate by filling out a self-reported version of a specific *** addition,they wentthrough a clinician-assisted version of this questionnaire,encompassing tools such as the Premature Ejaculation Diagnostic Tool(PEDT),the 6-item International Index of Erectile Function(IIEF-6),the Erection Hardness scale(EHs),and the MasturbationErection Index(MEI).Using the clinician-assisted version as a reference,we categorized patients and applied various statisticalmethods,such as the Chi-square test,intraclass correlation coefficient(ICC),logistic regression,and the Bland–Altman plot,to gauge *** our study with 322 participants,we found that while there were no notable discrepancies in error ratesbased on our categorization,certain scales showed significant differences in terms of overestimation and underestimation,withthe exception of the *** positive diagnosis rate consistency between the self-reported and clinician-assisted versions *** ICC values between the two versions across the scales were indicative of remarkable *** findings showthat the self-reported versions of tools such as EHs,IIEF-6,MEI,and PEDT are credible and hold clinical ***,employing a dual-diagnosis approach might be more prudent to circumvent potential misdiagnoses.

关键词： psychometry scale sexual function sexual health

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库夫施泰因在童话世界和无垠山野共振

环球人文地理 2024年第11期 144-152页

作者：十一 ARochau erika Karl Allen Lugmayer Nikolai sorokin Olivier pictureserver Roman Babakin stephan sühling Thomas Gross 摄图网

欧洲最适合隐居的地方在哪里？近日Lonely Planet公布的名单中，阿尔卑斯山脚下的库夫施泰因榜上有名。古典音乐环绕小镇，而走进大自然的方式有无数种：夏季徒步，冬季滑雪……库夫施泰因，奥地利西部的一个美丽小镇。得益于德、奥边...

欧洲最适合隐居的地方在哪里？近日Lonely Planet公布的名单中，阿尔卑斯山脚下的库夫施泰因榜上有名。古典音乐环绕小镇，而走进大自然的方式有无数种：夏季徒步，冬季滑雪……库夫施泰因，奥地利西部的一个美丽小镇。得益于德、奥边界的地理之势，无论从慕尼黑还是萨尔茨堡出发，都只需乘车约1小时就能到达。小镇夹在阿尔卑斯山的一个河谷，碧绿草坪、原始森林和清澈湖水环绕四周，八个村庄点缀其间，从高空俯瞰，犹如散落的珍珠。

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美国66号公路全美最著名的公路即将迎来100周年庆

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空中英语教室（高级版．彭蒙惠英语） 2024年第1期 6-8,38,39页

作者： erika Bolstad 不详

01从一开始,66号公路就代表着美国当代文化。1926年,这条连接芝加哥和洛杉矶的公路,标志着汽车的无限可能。20世纪30年代大萧条时期,66号公路是人们逃离尘暴区的东西向逃生路线。到了20世纪50年代,这条2400英里长的公路以二战后的公路... 详细信息

01从一开始,66号公路就代表着美国当代文化。1926年,这条连接芝加哥和洛杉矶的公路,标志着汽车的无限可能。20世纪30年代大萧条时期,66号公路是人们逃离尘暴区的东西向逃生路线。到了20世纪50年代,这条2400英里长的公路以二战后的公路冒险吸引着旅客。

关键词：大萧条时期逃生路线洛杉矶芝加哥当代文化

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新闻剪辑阅读新闻集锦,提升词汇能力

空中英语教室（高级版．彭蒙惠英语） 2024年第7期 22-24,44,45页

作者： erika Bolstad 不详

日课文及其配套音频因故删除,敬请广大读者谅解。美国各州释出优惠条件,争取芯片厂进驻自从2022年美国国会通过527亿美元的芯片法案,鼓励国内半导体制造设计与研发以来,各州无不竞相吸引芯片制造商。俗称芯片的半导体,几乎为生活的方方... 详细信息

日课文及其配套音频因故删除,敬请广大读者谅解。美国各州释出优惠条件,争取芯片厂进驻自从2022年美国国会通过527亿美元的芯片法案,鼓励国内半导体制造设计与研发以来,各州无不竞相吸引芯片制造商。俗称芯片的半导体,几乎为生活的方方面面提供原动力,各州都希望得到半导体产业带来的投资与高薪的工程及制造工作。

关键词：半导体产业芯片制造商半导体制造美国国会芯片厂新闻集锦美国各州词汇能力

Advantageous mechanochemical synthesis of copper(Ⅰ)selenide semiconductor,characterization,and properties

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Frontiers of Chemical science and Engineering 2022年第3期16卷 433-442页

作者： Katarína Gáborová Marcela Achimovičová Michal Hegedüs Vladimír Girman Mária Kaňuchová erika Dutková Institute of Geotechnics Slovak Academy of SciencesKošice04001Slovakia Institute of Metallurgy Faculty of MaterialsMetallurgy and RecyclingTechnical UniversityKošice04201Slovakia synthon s.r.o.Blansko67801Czech Republic Faculty of science Pavol JozefŠafárik UniversityKošice04154Slovakia Institute of Earth Resources Faculty of MiningEcologyProcess Control and GeotechnologiesTechnical UniversityKošice04200Slovakia

Copper(I)selenide-nanocrystalline semiconductor was synthesized via one-step mechanochemical synthesis after 5 min milling in a planetary ball *** kinetics of synthesis was followed by X-ray powder diffraction analysis and specific surface area measurements of milled 2Cu/se *** X-ray diffraction confirmed the orthorhombic crystal structure of Cu_(2)se with the crystallite size∼25 *** surface chemical structure was studied by X-ray photoelectron spectroscopy,whereby the binding energy of the Cu 2p and se 3d signals corresponded to Cu^(+)and se^(2−)oxidation *** electron microscopy revealed agglomerated nanocrystals and confirmed their orthorhombic structure,as *** optical properties were studied utilizing ultraviolet-visible spectroscopy and photoluminescence *** direct bandgap energy 3.7 eV indicated a blue-shift phenomenon due to the quantum size *** type of Cu_(2)se synthesis can be easily adapted to production dimensions using an industrial vibratory *** advantages of mechanochemical synthesis represent the potential for inexpensive,environmentally-friendly,and waste-free manufacturing of Cu_(2)se.

关键词： Cu_(2)se berzelianite nanocrystalline semiconductor mechanochemical synthesis planetary ball mill

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eUREkA! T cells answer nature’s call

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Cellular & Molecular Immunology 2023年第7期20卷 692-693页

作者： Beth Kelly erika L.Pearce Bloomberg-Kimmel Institute of Immunotherapy Department of OncologyJohns Hopkins University School of MedicineBaltimoreMDUSA

Nitrogen is critical for cell growth, proliferation, and function. Amino acid (AA) catabolism is a major source of intracellular nitrogen for biosynthesis but also generates the nitrogen-containing molecule ammonia (NH3+), which can accumulate to toxic levels in a cell if not exported to the circulation and detoxified by the urea cycle in the liver. In a recent paper in Nature Immunology, Tang et al. [1] discovered a functional urea cycle in memory T cells, which metabolizes ammonia, prevents its toxic accumulation.

关键词： function. ammonia cycle

source identification and global implications of black carbon

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Geoscience Frontiers 2022年第1期13卷 404-416页

作者： erika P.Blanco-Donado Ismael L.schneider Paulo Artaxo Jesus Lozano-Osorio Luana Portz Marcos L.s.Oliveira Department of Civil and Environmental Universidad de la CostaCUCBarranquilla080002Colombia Department of Applied Physics Institute of PhysicsUniversity of São PauloSP 05508-220Brazil Universidad de Lima Avenida Javier Prado Este 4600Santiago de Surco 1503Peru

Black carbon(BC)is one of the short-lived air pollutants that contributes significantly to aerosol radiative forcing and global climate *** is emitted by the incomplete combustion of fossil fuels,biofuels,and *** environments are quite complex and thus,the use of mobile jointly with fixed monitoring provides a better understanding of the dynamics of BC distribution in such *** present study addresses the measurement of BC concentration using real-time mobile and ambient monitoring in Barranquilla,an industrialized urban area of the Colombian Caribbean.A microaethalometer(MA200)and an aethalometer(AE33)were used for measuring the BC *** absorption Ångström exponent(AAE)values were determined for the study area,for identifying the BC emission *** results of the ambient sampling show that vehicle traffic emissions prevail;however,the influence of biomass burning was also *** mean ambient BC concentration was found to be 1.04±1.03μg/m^(3) and varied between 0.5 and 4.0μg/m^(3).From the mobile measurements obtained in real traffic conditions on the road,a much higher average value of 16.1±16.5μg/m^(3) was *** parts of the city showed BC concentrations higher than 20μg/m^(3).The spatial distribution of BC concentration shows that vehicle emissions and traffic jams,a consequence of road and transport infrastructure,are the factors that most affect the BC concentration.A comparison of results obtained from two aethalometers indicates that the concentrations measured by MA200 are 9%lower than those measured by *** AAE obtained was found to vary between 1.1 and 1.6,indicating vehicular emissions as the most crucial *** addition,it was observed that the BC concentration on working days was 2.5 times higher than on the weekends in the case of mobile monitoring and 1.5 times higher in the case of ambient monitoring.

关键词： Air pollution Black carbon spatial distribution source apportionment AbsorptionÅngström exponent

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Envita’s Precision Cancer Care: 35-Fold Improvement in Response Rates

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Journal of Cancer Therapy 2024年第4期15卷 99-120页

作者： sheba Goklany John C. Oertle III Ronald Matthias Jr. Daniel Warren David Medina Rory sears Robert Zieve Kendra Quart Christopher Aussems Jon Moma shannon Miller Zach Poteet Conner Coffin Courtney Middleton erika Ware Phylicia Zarnosky Julie Nowak Winlove suasin Daniel Conway Chad Burk Ruth Tan-Lim Dino Prato Envita Medical Centers Scottsdale AZ USA

New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United states. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.

关键词： Envita Medical Centers Late-stage Cancer Overall Response Rate Quality of Life Circulating Tumor Cells (CTCs) Mutant Allele Frequency (MAF) Precision Care

Neurodevelopmental in Relation to Breastfeeding–Experiences among Hungarian Preterm Infants at 12 Months of Corrected Age:Empirical study

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International Journal of Mental Health Promotion 2022年第5期24卷 699-709页

作者： Anna szabina szele Beáta erika Nagy Department of Pediatrics Faculty of MedicinePediatric Psychology and Psychosomatic UnitKálmán Laki Doctoral SchoolUniversity of DebrecenDebrecen4032Hungary Department of Pediatrics Faculty of MedicinePediatric Psychology and Psychosomatic UnitUniversity of DebrecenDebrecen4032Hungary

Preterm and low birth weight infants are at higher risk of neurodevelopmental outcomes;breastfeeding offers sev-eral beneﬁcial aspects for *** study aimed to describe the average neurodevelopmental outcomes of pre-term infants and examine the associations between neurodevelopment and breastfeeding among Hungarian preterm infants at 12 months of corrected age.154 preterm infants with low birth weight(s were participated in this ***-III screening Test(Bayley scales of Infant and Toddler Develop-ment screening Test,Third Edition)was administered to measure the cognitive,language and motor skills of infants;breastfeeding data was obtained through parental *** analyze data,independent sample t-test or the Welch t-test,Mann-Whitney tests,Chi-square tests of independence and spearman’s rank correlation test were used *** the risk of developmental delay,Receptive and Expressive language and Fine motor subscales were the *** of the associations between breastfeeding and neurodevelopmental per-formance identiﬁed signiﬁcantly higher cognitive(U=2047.5;P=0.023)andﬁne motor(U=2096.0;P=0.037)skills in infants who were *** found signiﬁcant positive correlations between the duration of breastfeeding and cognitive,expressive language andﬁne motor *** study draws the attention to the importance of breastfeeding and early *** research is required to examine the casual relationship between neurodevelopmental outcomes and breastfeeding.

关键词： Preterm infants low birth weight breastfeeding duration of breastfeeding neurodevelopmental outcomes