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Solid pseudopapillary neoplasm-diagnostic approach and postsurgical follow up:Three case reports and review of literature

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World Journal of Clinical Cases 2021年第7期9卷 1682-1695页

作者： Mohammad Abudalou Eduardo A Vega Rohit Dhingra erik holzwanger Sandeep Krishnan Svetlana Kondratiev Ali Niakosari Claudius Conrad Christopher G Stallwood Department of Internal Medicine St.Elizabeth Medical CenterBrightonMA 02135United States Department of General Surgery St.Elizabeth Medical CenterBrightonMA 02135United States Department of Gastroenterology Tufts Medical CenterBostonMA 02111United States Department of Gastroenterology St.Elizabeth Medical CenterBrightonMA 02135United States Department of Pathology St.Elizabeth Medical CenterBrightonMA 02135United States Department of Radiology St.Elizabeth Medical CenterBrightonMA 02135United States

BACKGROUND Solid pseudopapillary neoplasm(SPN)is a rare tumor that was first described by Frantz in *** this tumor is benign,some may have malignant potential that can be predicted based on demographics,imaging characteristics,and pathologic *** case series presents 3 SPN cases with discussion on gender differences,preoperative predictors of malignancy,and a suggested algorithm for diagnostic approach as well as post-surgical follow *** SUMMARY Three adult patients in a tertiary hospital found to have SPN,one elderly male and two young *** of the cases presented with abdominal pain and were discovered *** cases underwent endoscopic ultrasound with immunohistochemical staining(which were consistent with SPN before undergoing surgery),and one case underwent surgery directly after *** average tumor size was 5 *** was confirmed by *** patients had post-surgical complications requiring *** Demographic and imaging characteristics can be sufficient to establish diagnosis for SPN,while malignant cases require pre-operative evaluation with endoscopic ultrasound fine needle aspiration/fine needle biopsy.

关键词： Pancreas Pancreatic cyst Pancreatic neoplasms Solid pseudopapillary neoplasm Pancreatectomy Case report

Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients

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World Journal of Hepatology 2019年第6期11卷 522-530页

作者： Matthew Fasullo Prashanth Rau Dong-Qi Liu erik holzwanger Jomol P Mathew Yurima Guilarte-Walker Gyongyi Szabo Department of Medicine University of Massachusetts Medical SchoolWorcesterMA 01605United States Department of Population and Quantitative Health Sciences University of Massachusetts Medical SchoolWorcesterMA 01605United States Department of Data Sciences and Technology Information TechnologyUniversity of Massachusetts Medical SchoolWorcesterMA 01605United States

BACKGROUND Liver cirrhosis is the late stage of hepatic fibrosis and is characterized by portal hypertension that can clinically lead to decompensation in the form of ascites,esophageal/gastric varices or *** most common sequelae associated with liver cirrhosis are neurologic and neuropsychiatric impairments labeled as hepatic encephalopathy(HE).Well established triggers for HE include infection,gastrointestinal bleeding,constipation,and *** to the gut microbiome is one of the leading ammonia producers in the body,and therefore may make patients more susceptible to *** To investigate the relationship between the use of proton pump inhibitors(PPIs)and HE in patients with *** This is a single center,retrospective *** were included in the study with an admitting diagnosis of *** degree of HE was determined from subjective and objective portions of hospital admission notes using the West Haven *** primary outcome of the study was to evaluate the grade of HE in PPI users versus non-users at admission to the hospital and throughout their hospital *** outcomes included rate of infection,gastrointestinal bleeding within the last 12 mo,mean ammonia level,and model for end-stage liver disease scores at *** The HE grade at admission using the West Haven Criteria was 2.3 in the PPI group compared to 1.7 in the PPI nonuser group(P=0.001).The average length of hospital stay in PPI group was 8.3 d compared to 6.5 d in PPI nonusers(P=0.046).Twenty-seven(31.8%)patients in the PPI user group required an Intensive Care Unit admission during their hospital course compared to 6 in the PPI nonuser group(16.7%)(P=0.138).Finally,10(11.8%)patients in the PPI group expired during their hospital stay compared to 1 in the PPI nonuser group(2.8%)(P=0.220).CONCLUSION Chronic PPI use in cirrhotic patients is associated with significantly higher average West Haven Criteria for HE compared to pa

关键词： Cirrhosis Hepatic encephalopathy Proton pump inhibitors Hepatology Proton pump inhibitor

An approach of the internal friction-dependent temperature changes for conventional and pure biogenic lubricating greases

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Friction 2024年第4期12卷 780-795页

作者： Leif AHME erik KUHN MiguelÁngel DELGADO Department of Mechanical Engineering and Production Management Hamburg University of Applied SciencesHamburg 20099Germany Department of Chemical Engineering Research in Product Technology and Chemical Processes(Pro2TecS)University of HuelvaHuelva 21071Spain

This work investigated the temperature changes inside the bulk of lubricating greases under controlled high-shear stress conditions(250-500 s-1).For this purpose,a newly developed temperature-measuring cell called Calidus was successfully *** temperature changes(ΔT)have been related to the greases'components(thickener,base oil-type,and composition)and the structural degradation of the lubricating ***,a theoretical approach was proposed for calculating the internal temperature change of lubricating greases during shear *** greases showed an internal temperature profile characterised by a sudden rise inΔT within the first 4 h from starting the test and subsequentΔT decay until it reaches the steady state ***,it was found that greases C1 and C5,formulated with lithium and calcium soap,respectively,with different soap content(16.1 wt%and 9.7 wt%,respectively),but the same base castor oil,showed the highest value of the maximumΔT,c.a.3.2 K,and the most drastic drop ofΔ*** greases showed both the highest specific densities and heat *** addition,they showed the lowest ratio of expended energies(Rtee),which means more structural degradation in the stressed *** the contrary,the grease C3,with 13 wt%of Li-soap but the lowest base oil's viscosity,showed the lowest maximumΔT and the temperature profile was characterised by a moderate variation ofΔT along the *** biogenic grease B3 developed a low-temperature change in the group of pure bio-genic greases close to grease C3.

关键词： shear-induced structural degradation rheology temperature measurements lubricating greases density lubricating greases specific heat capacities

A taxonomy of built asset information coupling

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Frontiers of Engineering Management 2024年第2期11卷 247-268页

作者： Saman DAVARI erik POIRIER Department of Construction Engineering Ecole de technologie superieureMontreal H3C 1K3Canada

The digital transformation of the built asset industry is moving toward closer integration of physical and digital assets and *** the framework of Cyber-Physical Systems(CPSs)and Digital Twins(DTs),an increasing number of studies focus on the technical aspects of CPS and ***,a unified framework describing the dimensions and characteristics essential for integrating lifecycle information remains *** leverage these concepts effectively,it is necessary to develop new frameworks to classify and put into relationship various components that comprise the lifecycle information integration of physical and digital assets and *** paper addresses these gaps by proposing a taxonomy of Built Asset Lifecycle Information Couples,which outlines the dimensions and characteristics crucial for the lifecycle information integration of built assets and *** proposed taxonomy contributes to the efforts aimed at organizing the knowledge domain of lifecycle information management in the built environment.

关键词： asset coupling taxonomy digitalization lifecycle information management built environment

Brassinosteroid biosynthesis and signaling:Conserved and diversified functions of core genes across multiple plant species

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Plant Communications 2024年第9期5卷 72-100页

作者： Brian Zebosi erik Vollbrecht Norman B.Best Department of Genetics Development and Cell BiologyIowa State UniversityAmesIA 50011USA Interdepartmental Genetics and Genomics Graduate Program Iowa State UniversityAmesIA 50011USA USDA-ARS Plant Genetics Research UnitColumbiaMO 65201USA

Brassinosteroids(BRs)are important regulators that control myriad aspects of plant growth and development,including biotic and abiotic stress responses,such that modulating BR homeostasis and signaling presents abundant opportunities for plant breeding and crop *** and other proteins involved in the biosynthesis and signaling of BRs are well understood from molecular genetics and phenotypic analysis in Arabidopsis thaliana;however,knowledge of the molecular functions of these genes in other plant species,especially cereal crop plants,is *** this manuscript,we comprehensively review functional studies of BR genes in Arabidopsis,maize,rice,Setaria,Brachypodium,and soybean to identify conserved and diversified functions across plant species and to highlight cases for which additional research is in *** performed phylogenetic analysis of gene families involved in the biosynthesis and signaling of BRs and re-analyzed publicly available transcriptomic *** trees coupled with expression data provide a valuable guide to supplement future research on BRs in these important crop species,enabling researchers to identify gene-editing targets for BR-related functional studies.

关键词： brassinosteroids maize rice Setaria soybean Brachypodium Arabidopsis

The Ti-TAN plasmid toolbox for TurboID-based proximity labeling assays in Nicotiana benthamiana

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Journal of Integrative Plant Biology 2024年第2期66卷 166-168页

作者： Huang Tan Yu Zhou erik Dinius Rosa Lozano-Durán Department of Plant Biochemistry Center for Plant MolecularBiology(ZMBP)Eberhard Karls UniversityTubingenD‐72076Germany

Protein-protein interactions and the formation of protein complexes play a central role in the regulation of virtually all aspects of *** identification and characterization of interactions between proteins is the bas... 详细信息

关键词： proximity complexes enable

Coated boron layers by boronization and a real-time boron coating using an impurity powder dropper in the LHD

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Plasma Science and Technology 2024年第8期26卷 25-31页

作者： Naoko ASHIKAWA Robert LUNSFORD Federico NESPOLI erik GILSON Yaowei YU Jiansheng HU Shinichiro KADO National Institute for Fusion Science Toki 509-5292Japan Princeton Plasma Physics Laboratory Princeton NJ 08540United States of America Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People’s Republic of China Institute of Advanced Energy Kyoto UniversityKyoto 611-0011Japan

In the Large Helical Device(LHD),diborane(B2H6)is used as a standard boron source for boronization,which is assisted by helium glow *** 2019,a new Impurity Powder Dropper(IPD)system was installed and is under evaluation as a real-time wall conditioning *** the LHD,which is a large-sized heliotron device,an additional helium(He)glow discharge cleaning(GDC)after boronization was operated for a reduction in hydrogen recycling from the coated boron *** operational time of 3 h was determined by spectroscopic data during glow discharges.A flat hydrogen profile is obtained on the top surface of the coated boron on the specimen exposed to *** results suggest a reduction in hydrogen at the top surface by *** oxygen in coated boron was obtained by boronization,and the coated boron,which has boron-oxide,on the first wall by B-IPD was also *** the difference in coating areas between B2H6 boronization and B-IPD operation,it would be most effective to use the IPD and B2H6 boronization coating together for optimized wall conditioning.

关键词： boron layer oxygen impurity hydrogen recycling impurity powder dropper LHD EAST

Increasing phosphorus fertilizer value of recycled iron phosphates by prolonged flooding and organic matter addition

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Pedosphere 2024年第3期34卷 631-640页

作者： Rochelle Joie SARACANLAO Hannah VAN RYCKEL Mieke VERBEECK Maarten EVERAERT erik SMOLDERS Division of Soil and Water Management Department of Earth and Environmental ScienceKU LeuvenKasteelpark Arenberg 20Heverlee B-3001(Belgium) Soil Service of Belgium.Willem De Croylaan 48 Leuven 3001(Belgium)

Iron(Fe)minerals are commonly used to remove phosphorus(P)from waste streams,producing P-loaded Fe(Ⅲ)oxides or Fe(Ⅱ)phosphate minerals(e.g.,vivianite).These minerals may be used as fertilizers to enhance P circularity if solubilized in ***,we tested the P fertilizer value of recycled Fe phosphates(FePs)in a pot trial and in an incubation experiment,hypothesizing that P release from FePs is possible under Fe(Ⅲ)-reducing ***,a pot trial was set up with rice(Oryza sativa)in all combinations of soil flooding or not,three P-deficient soils(acid,neutral,and calcareous),and six FePs(three Fe(Ⅲ)Ps and three Fe(Ⅱ)Ps)referenced to triple superphosphate(TSP)or zero *** P uptake responded to TSP application in all treatments but only marginally to *** redox potential did not decrease to-200 mV by flooding for a brief period(13 d)during the pot trial.A longer incubation experiment(60 d)was performed,including a treatment of glutamate addition to stimulate reductive conditions,and P availability was assessed with CaCl_(2)extraction of *** addition and/or longer incubation lowered soil redox potential to<-100 *** the longer term,Fe(Ⅲ)minerals released P,and adequate P was reached in the calcareous soil and in the neutral soil amended with Fe(Ⅲ)*** can be concluded that prolonged soil flooding and organic matter addition can enhance the P fertilizer efficiency of ***,application of FeP in powder form may enhance P availability.

关键词： agronomic efficiency circular economy P-loaded Fe(Ⅲ)oxides paddy soil vivianite redox

The 2024 Compendium of Physical Activities and its expansion

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Journal of Sport and Health Science 2024年第1期13卷 1-2,F0003页

作者： Stephen D.Herrmann erik A.Willis Barbara E.Ainsworth Kansas Center for Metabolism and Obesity Research University of Kansas Medical CenterKansas CityKS 66160USA Center for Health Promotion and Disease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA School of Exercise and Health Shanghai University of SportShanghai 200438China

First developed 30 years ago,the Compendium of Physical Activities(Compendium)was created to provide a standardized way of measuring and classifying specific physical activities(PAs),allowing researchers and health professionals to assess the energy expenditure and health benefits associated with different PA.1Since its inception,the Compendium has been widely utilized and recognized as a fundamental PA and health resource.

关键词： has utilized classify