检索结果-南通市图书馆

Optimizing dietary lipid use to improve essential fatty acid status and reproductive performance of the modern lactating sow:a review

引用

Journal of Animal science and Biotechnology 2016年第3期7卷 272-289页

作者： David s.Rosero R.Dean Boyd Jack Odle eric.van Heugten The Hanor Company FranklinKY 42134USA Department of Animal science North Carolina State UniversityRaleighNC 27695USA

Dietary lipid supplementation benefits the prolific and high-producing modern lactating sow. A comprehensive review of recent studies showed that lipid supplementation increases average daily energy intake, which is partitioned for lactation as indicated by greater milk fat output and improved litter growth rate. Recent compelling findings showed that addition of particular lipids during lactation improved the subsequent reproductive outcome of sows. such benefits were related to the level of dietary essential fatty acids（EFA, linoleic acid, C18：2n-6; and α-linolenic acid, C18：3n-3） during lactation. Lactation diets without supplemental EFA resulted in a pronounced negative balance（intake minus milk output） of linoleic（-25.49 g/d） and α-linolenic acid（-2.75 g/d）; which compromised sow fertility（farrowing rate 〈 75 % and culling rates 〉 25 % of weaned sows）. This phenomenon seems to be increasingly important with advancing sow age because of a progressive reduction of body EFA pool over successive lactations. The net effect of supplemental EFA during lactation was to create a positive EFA balance, which improved the subsequent reproduction of sows. Adequate linoleic acid intake improved the proportion of sows that farrowed in the subsequent cycle（Farrowing rate（%） = [（-1.5 × 10^-3× linoleic acid intake（g/d）^2）＋（0.53 × linoleic acid intake（g/d））＋（45.2）]; quadratic P = 0.002, R^2= 0.997, RMsE = 0.031）. In addition, increasing linoleic acid intake increased the number of pigs born in the subsequent cycle（total pigs born（n） = [（9.4 × 10^-5× linoleic acid intake（g/d）^2）＋（0.04 × linoleic acid intake（g/d））＋（10.94）]; quadratic P = 0.002, R^2= 0.997, RMsE = 0.031）. supplemental α-linolenic acid resulted in a rapid return to estrus（sows bred： sows weaned = 94.2 %; wean-to-estrus interval = 4.0 d） and achieved a high retention of pregnancy（sows pregnant： sows bred = 98 %）. Collectively, we conclude that a minimum dietary intake of10 g/d of α-linolenic acid, simultaneous wit

关键词： Essential fatty acids Lactating sow subsequent reproduction supplemental lipids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion

引用

The Journal of Biomedical Research 2014年第3期28卷 178-193页

作者： eric.Fisher Elizabeth Lake Roger s McLeod Biochemistry & Molecular Biology Faculty of MedicineDalhousie University

Apolipoprotein B （apoB） is the main protein component of very low density lipoprotein （VLDL） and is necessary for the assembly and secretion of these triglyceride （TG）-rich particles. Following release from the liver, VLDL is converted to low density lipoprotein （LDL） in the plasma and increased production of VLDL can therefore play a detrimental role in cardiovascular disease. Increasing evidence has helped to establish VLDL assembly as a target for the treatment of dyslipidemias. Multiple factors are involved in the folding of the apoB protein and the formation of a secretion-competent VLDL particle. Failed VLDL assembly can initiate quality control mechanisms in the hepatocyte that target apoB for degradation. ApoB is a substrate for endoplasmic reticulum associated degradation （ERAD） by the ubiquitin proteasome system and for autophagy. Efficient targeting and disposal of apoB is a regu- lated process that modulates VLDL secretion and partitioning of TG. Emerging evidence suggests that significant overlap exists between these degradative pathways. For example, the insulin-mediated targeting of apoB to autop- hagy and postprandial activation of the unfolded protein response （UPR） may employ the same cellular machinery and regulatory cues. Changes in the quality control mechanisms for apoB impact hepatic physiology and pathology states, including insulin resistance and fatty liver. Insulin signaling, lipid metabolism and the hepatic UPR may impact VLDL production, particularly during the postprandial state. In this review we summarize our current understanding of VLDL assembly, apoB degradation, quality control mechanisms and the role of these processes in liver physiology and in pathologic states.

关键词： apolipoprotein B very low density lipoprotein proteasome ubiquitin autophagy steatosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adaptive introductions:How multiple experiments and comparisons to wild populations provide insights into requirements for long-term introduction success of an endangered shrub

引用

Plant Diversity 2016年第5期38卷 238-246页

作者： eric.s.Menges stacy A.smith Carl W.Weekley Archbold Biological station 123 Main DriveVenusEL 33960USA

Recovery of an imperiled plant species may require augmentation of existing populations or creation of new *** of such projects have been conducted over the last few decades,but there is a bias in the literature favoring successes over *** this paper,we evaluate a series of introductions that experimentally manipulated microhabitat and fire in an adaptive introduction *** 2002 and 2012,we(and our collaborators) carried out ten introductions and augmentations of Florida ziziphus Pseudoziziphus(Condalia,Ziziphus) celata,a clonal shrub limited to very small populations and narrowly endemic to pyrogenic central Florida *** of the introductions were designed as experiments to test hypotheses about how demographic performance was affected by microhabitat,fire,and propagule *** transplants had high survival(nconsistent growth,and little transition to reproduction,while introduced seeds had low germination and *** were more efficient than seeds as translocation ***(***) sites supported generally higher transplant and seedling survival and seed germination percentages,but growth responses varied among *** irrigation increased transplant survival and seed germination,but otherwise seedling and plant survival and growth were not significantly *** to expectations based on wild populations,introduced propagules have not been more successful in unshaded sites,suggesting that Florida ziziphus has broader microhabitat preferences than *** to wild plants,introduced plants had similar survival and responses to fire,slower growth,and more delayed *** plants had no clonal *** no introduced population has demonstrated a capacity for long-term viability,one augmented population has flowered and produced viable *** that Florida ziziphus genets are long-lived,low levels of sexual reproduction may be a

关键词： Florida ziziphus Translocation Augmentation Rare plant Florida sandhill Microhabitat

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mode-synthesizing atomic force microscopy for 3D reconstruction of embedded low-density dielectric nanostructures

引用

Nano Research 2015年第7期8卷 2199-2205页

作者： Pauline Vitry eric.BouriUot Cedric Plassard Yvon Lacroute eric.Calkins Laurene Tetard eric.Lesniewska Avenue Alain savary UMR CNRs 6303 Physics Department University of Bourgogne 210786 Cedex France Nanoscience Technology Center University of Central Florida Orlando FL 32826 USA Department of Physics University of Central Florida Orlando FL 32826 USA

Challenges in nanoscale characterization call for non-invasive, yet sensitive subsurface characterization of low-density materials such as polymers. In this work, we present new evidence that mode-synthesizing atomic force microscopy can be used to detect minute changes in low-density materials, such as those engendered in electro-sensitive polymers during electron beam lithography, surpassing all common nanoscale mechanical techniques. Moreover, we propose 3D reconstruction of the exposed polymer regions using successive high-resolution frames acquired at incremental depths inside the sample. In addition, the results clearly show the influence of increasing dwell time on the depth profile of the nano-sized exposed regions. Hence, the simple approach described here can be used for achieving sensitive nanoscale tomography of soft materials with promising applications in material sciences and biology.

关键词： na_noscale subsurface imaging tomic force microscopy,3D reconstruction, nanoscale tomography acoustic microscopy dielectic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Towards a bisimulation theory for open synchronized networks of automata

引用

science China(Information sciences) 2016年第5期59卷 21-23页

作者： eric.MADELAINE Min ZHANG INRIA 2004 rte des Lucioles shanghai Key Laboratory of Trustworthy Computing MOE IntalJoint Laboratory of Trustworthy SoftwareECNU

Dear editor,Open parameterised Networks of synchronized automata(p Nets)are new semantic objects that we propose for defining the semantics of simple or complex composition operators for distributed *** p Nets have an operational semantics,using open transitions that include symbolic hypotheses on the behavior of the p Nets"holes".We discuss when this semantics can be finite and how to compute it *** define bisimulation equivalences between open p Nets,and we explore under which hypotheses these equivalences are compatible with composition and are decidable.

关键词： Towards a bisimulation theory for open synchronized networks of automata

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis

引用

science China(Life sciences) 2010年第2期53卷 195-203页

作者： MEIssNER eric Lineberger Comprehensive Cancer Center Department of Microbiology and ImmunologySchool of MedicineUniversity of North Carolina at Chapel Hill

A robust animal model for "hypothesis-testing/mechanistic" research in human immunology and immuno-pathology should meet the following ***,it has well-studied hemato-lymphoid organs and target cells similar to those of ***,the human pathogens establish infection and lead to relevant ***,it is genetically inbred and can be manipulated via genetic,immunological and pharmacological *** human-tropic pathogens such as HIV-1 fail to infect murine cells due to the blocks at multiple steps of their life *** mouse with a reconstituted human immune system and other human target organs is a good candidate.A number of human-mouse chimeric.models with human immune cells have been developed in the past 20 years,but most with only limited success due to the selective engraftment of xeno-reactive human T cells in hu-PBL-sCID mice or the lack of significant human immune responses in the sCID-hu Thy/Liv *** review summarizes the current understanding of HIV-1 immuno-pathogenesis in human patients and in sIV-infected primate *** also reviews the recent progress in the development of humanized mouse models with a functional human immune system,especially the recent progress in the immunodeficient mice that carry a defective gammaC ***/sCID/gammaC-/(NOG or NsG) or the Rag2-/-/gammaC-/double knockout (DKO) mice,which lack NK as well as T and B cells (NTB-null mice),have been used to reconstitute a functional human immune system in central and peripheral lymphoid organs with human CD34+ *** NTB-hu HsC humanized models have been used to investigate HIV-1 infection,immuno-pathogenesis and therapeutic *** models,with further improvements,will contribute to study human immunology,human-tropic pathogens as well as human stem cell biology in the tissue development and function in vivo.

关键词： Humanized mouse models HIV-1 NOD/sCID/gammaC-/- Rag2-/-/gammaC-/-

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ferroelectricity Induced by Oxygen Vacancies in Rhombohedral ZrO_(2) Thin Films

引用

Energy & Environmental Materials 2024年第1期7卷 229-237页

作者： Veniero Lenzi José P.B.silva Břetislav Šmíd Vladimir Matoín Cosmin M.Istrate Corneliu Ghica Judith L.MacManus-Driscoll Luís Marques Physics Center of Minho and Porto Universities(CF-UM-UP) University of MinhoCampus de Gualtar 4710-057Braga Portugal Laboratory of Physics for Materials and Emergent Technologies LapMETUniversity of Minho4710-057Braga Portugal Department of surface and Plasma science Faculty of Mathematics and PhysicsCharles UniversityV Holešovičkách 218000Prague 8 Czech Republic National Institute of Materials Physics 105 bis Atomistilor 077125Magurele Romania Department of Materials science and Metallurgy 27 Charles Babbage Rd.Cambridge CB3 OFSUK

Rhombohedral phase Hf_(x)Zr_(1.x)O_(2)(HZO,x from 0 to 1)films are promising for achieving robust ferroelectric polarization without the need for an initial wake-up pre-cycling,as is normally the case for the more commonly studied orthorhombic ***,a large spontaneous polarization observed in rhombohedral films is not fully understood,and there are also large discrepancies between experimental and theoretical *** this work,in rhombohedral ZrO_(2)thin films,we show that oxygen vacancies are not only a key factor for stabilizing the phase,but they are also a source of ferroelectric polarization in the *** is shown experimentally through the investigation of the structural properties,chemical composition and the ferroelectric properties of the films before and after an annealing at moderate temperature(400℃)in an oxygen environment to reduce the V_(o)concentration *** experimental work is supported by density functional theory(DFT)calculations which show that the rhombohedral phase is the most stable one in highly oxygen defective ZrO_(2)*** DFT calculations also show that V_(o)contribute to the ferroelectric *** findings reveal the importance of V_(o)for stabilizing rhombohedral ZrO_(2)thin films with superior ferroelectric properties.

关键词： charged defects ferroelectric polarization rhombohedral phase stability zirconia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epidemiological, Clinical Aspects and Outcome of Measles in a Low-Income Country in 2023

引用

Open Journal of Pediatrics 2024年第1期14卷 139-148页

作者： sime Tchouamo Arielle Annick Enyama Dominique Noukeu Diomède Atyam Ekotto Marie Christine Abouame Palma Haoua Epee Ngoue Jeannette Kago Tague Daniel Armand Touka eric.Brice Tasse simo Nathalie Ines Nguéfack Félicité Faculty of Medicine and Pharmaceutical sciences of University of Dschang Dschang Cameroon Gynaeco-Obstetric and Pediatric Hospital of Yaounde Yaounde Cameroon Gynaeco-Obstetric and Pediatric Hospital of Douala Douala Cameroon Regional Annex Hospital of Dschang Dschang Cameroon Faculty of Medicine and Biomedical sciences of University of Garoua Garoua Cameroon Faculty of Medicine and Biomedical sciences of University of Yaounde 1 Yaounde Cameroon West Regional Delegation of Public Health Bafoussam Cameroon

Introduction: Measles remains a worrying health problem in sub-saharan African countries. There have been measles outbreaks in Cameroon with the most recent occurring between October 2022 and september 2023. The Centre region of Cameroon was the most affected in the country and being at the frontline of the fight against this illness, we conducted this study in order to determine the epidemiological and clinical characteristics as well as the outcome of children who contracted the measles and were hospitalized at the Yaoundé Gynaeco-Obstetric and Pediatric Hospital. Methodology: We conducted a cross-sectional descriptive and prospective study for one year from October 2022 to November 2023 corresponding to the duration of the outbreak. We included all children admitted in the pediatric unit for measles and its complications during this period. Results: In total, 60 children were enrolled. Their caregivers were mostly their mothers who had a mean age of 34.71 ± 9.55 years living in significant precarious conditions for the majority. The median age of children was 16 months (09 - 30 months). Twenty six percent of children (16) were less than 9 months. Girls were predominant (55%). Most children were not up to date with their routine EPI vaccination (80%) and most did not receive the measles and Rubella vaccine (76.67%). Clinical manifestations, included fever, conjunctivitis, and cough. skin rash and catarrh (98.33% and 86.67% respectively) are the case definition signs of measles. The outcome was unfavorable for 4 children. One had a neurological disorder: coma and three presented with pneumonia and severe respiratory distress (6.67%). Conclusion: Measles is still being a reality and claiming lives in our context, emphasis should be made on immunization coverage and if possible, advocacies should be formulated to decrease the age of measles vaccine administration.

关键词： Measles Complications Low-Income Countries

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Osteoarticular Lesions of the shoulder Girdle by Hippopotamus Bite: Highly septic Lesion

引用

Open Journal of Orthopedics 2024年第2期14卷 114-121页

作者： Jr Pierre Germain Ochou Achié Jean Régis Akobe Yao Aboh Ganyn Robert Arnaud Assere Kouamé Jean-eric.Kouassi Adelaïde Aya Natacha Kouassi Ibrahim soumahoro Zolopégué Marcel soro sédi Loues De Randolphe Akpro Gbalé Yannick Blé Kouamé Innocent M’bra Loukou Blaise Yao Bada Juste Léopold Niaorésery Koffi Léopold Krah Michel Kodo Department of Orthopaedic and Traumatological surgery Bouaké University Hospital Bouaké Ivory Coast Raoul Follereau Institute Manikro Centre Bouaké Ivory Coast

Hippopotamus bites are rare in medical consultations, despite several studies exposing their aggressive character. A case of a hippopotamus bite on the shoulder of a fisherman has been reported. In addition to the osteoarticular aspect representing a therapeutic problem, the infectious aspect was marked by sepsis, with a death in less than 48 hours. Based on this observation, a protocol for the initial management of large animal bites was submitted.

关键词： Bite Hippopotamus septic shock

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

苦瓜果汁对链脲霉素诱导的大鼠糖尿病的影响

引用

国外医学（中医中药分册） 1992年第1期14卷 14-15页

作者： eric.,HK 李宗友

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：