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Longitudinal analysis of quantitative biomarkers using projection-resolved OCT angiography in retinal vein occlusion

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Annals of Eye Science 2021年第2期6卷 19-31页

作者： Alexandra Miere Donato Colantuono Camille Jung Agnès Glacet-Bernard Severine Becuwe eric Petit eric souied Department of Ophthalmology Centre Hospitalier Intercommunal de CréteilUniversitéParis EstCréteilFrance Laboratory of Images Signals and Intelligent Systems Laboratory(LISSI/EA 3956)University Paris-EstCréteilFrance Clinical Research Center GRC Maculaand Biological Ressources CenterCentre Hospitalier Intercommunal de CréteilCréteilFrance UNIACT NeurospinISVFJCEAGif-sur-YvetteFrance

Background:To evaluate a fully automated vascular density(VD),skeletal density(SD)and fractal dimension(FD)method for the longitudinal analysis of retinal vein occlusion(RVO)eyes using projection-resolved optical coherence tomography angiography(OCTA)images and to evaluate the association between these quantitative variables and the visual prognosis in RVO ***:Retrospective longitudinal observational case *** presenting with RVO to Creteil University Eye Clinic between October 2014 and December 2018 and healthy controls were retrospectively *** 1 consisted of central RVO(CRVO)eyes,group 2 consisted of eyes with branch RVO(BRVO)and group 3 of healthy control *** acquisitions(AngioVue RTVue XR Avanti,Optovue,Inc.,Freemont,CA)were performed at baseline and last follow up ***,SD,and FD analysis were computed on OCTA superficial and deep vascular complex(SVC,DVC)images at baseline and final follow up using an automated *** regression was performed to find if and which variable(VD,SD,FD)was predictive for the visual ***:Forty-one eyes,of which 21 consecutive eyes of 20 RVO patients(13 CRVO in group 1,8 BRVO in group 2),and 20 eyes of 20 healthy controls were *** the level of SVC,VD and FD were significantly lower in RVO eyes compared to controls(P<0.0001 and P=0.0008 respectively).Best-corrected visual acuity(BCVA)at last follow-up visit was associated with baseline VD(P=0.013),FD(P=0.016),and SD(P=0.01)at the level of the SVC,as well as with baseline FD at the DVC level(P=0.046).Conclusions:Baseline VD,SD,and FD are associated with the visual outcome in RVO *** parameters seem valuable biomarkers and may help improve the evaluation and management of RVO patients.

关键词： Retinal vein occlusion(RVO) vascular density(VD) optical coherence tomography angiography(OCTA) fractal dimension(FD) image analysis

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Oculoplastic publication trends in general ophthalmology journals

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International Journal of Ophthalmology(English edition) 2022年第11期15卷 1852-1856页

作者： Jean-Paul Dray Nur Khatib eric souied Peerooz Saeed Guy Ben Simon Juliana Gildener-Leapman Ofira Zloto Department of Ophthalmology Centre Hospitalier Intercommunal de CreteilCreteil 94000France Orbital Center Department of OphthalmologyAmsterdam University Medical CentersAmsterdam 1105the Netherlands Goldschleger Eye Institute Sheba Medical CenterAffiliated to the Sackler Faculty of MedicineTel Aviv UniversityTel Aviv6997801Israel Meir Medical Center Kfar Saba 4428164Israel

AIM: To examine the publication trend of oculoplastic articles throughout the last decade in general ophthalmology ***: A review of all abstracts published between Januar y 2010 to December 2019 in general, clinical ophthalmic journals was conducted. Articles that were categorized as original articles in general and clinical journals were included in the ***: Totally 10 281 abstracts were included. Of them 465(4.5%) were oculoplastic publications. The mean number of annual-publications was 46.5 and the mean annual-rate of oculoplastic publications was 4.51%. A significant decreasing trend in the number of oculoplastic publication in the last decade was found(P<0.01, R^(2)=0.770). However, there was no significant change in the annual-rate of oculoplastic publications during the last decade(P=0.191, R2=0.203). From the 465 oculoplastic articles: 179(38.5%) were articles about eyelid diseases, 160(34.40%) were about orbit diseases, 92(19.80%) were about lacrimal diseases and 34(7.30%) were about thyroid eye disease(TED). A significant decreasing trends in the number of orbital and eyelids publications were found(P<0.01, P<0.01). However, there were no significant changes in the annual-rate of orbital, eyelids, TED and lacrimal-diseases publications throughout the last ***: Oculoplastic subspecialty deals with a wide range of pathologies in different ages. However, less than 5% of the articles in general, clinical, high impact factor ophthalmology journals are about oculoplastic diseases. One of the best way for ophthalmologists from different subspecilties, nowadays, to be updated, is to read highimpact-factor, general ophthalmology journals. Therefore, it is important that those journals will include articles about breakthroughs in oculoplastic.

关键词： oculoplastic publications journals general articles ophthalmology

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