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界面超分子化学与响应性功能表面(英文)

化学进展 2012年第1期24卷 1-7页

作者：万鹏博 hill eric h. 张希有机光电子与分子工程教育部重点实验室清华大学化学系北京100084 化学和核工程系生物医学工程中心新墨西哥大学阿尔布开克新墨西哥87131-1341美国

超分子化学和界面的结合有效地促进了超分子化学和胶体与界面科学的发展。刺激响应性超分子界面,因在外界刺激作用下能够引起界面物理化学性质的改变并带来新的界面功能,而受到广泛的关注。近年来,溶液中基于偶氮苯-环糊精主客体相互作... 详细信息

超分子化学和界面的结合有效地促进了超分子化学和胶体与界面科学的发展。刺激响应性超分子界面,因在外界刺激作用下能够引起界面物理化学性质的改变并带来新的界面功能,而受到广泛的关注。近年来,溶液中基于偶氮苯-环糊精主客体相互作用的超分子组装体已经得到了广泛的研究。我们将溶液中基于偶氮苯-环糊精主客体作用的可控可逆超分子组装体转移到界面上,构筑了具有刺激响应性的功能化超分子界面,并实现了表面浸润性的可逆调控、生物大分子的可控吸附与脱附、光可控的生物电化学催化等功能。我们期待类似的概念可以拓展到其他超分子体系,构筑具有特定结构的功能界面。

关键词：界面超分子化学响应性功能界面主客体化学蛋白质固定与释放生物电化学催化

Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy： a comparative study for sh.rt-term outcomes

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Frontiers of Medicine 2015年第3期9卷 356-360页

作者： eric C. h. Lai Ch.ng Ngai Tang Department of Surgery Pamela Youde Nethersole Eastern Hospital Chai Wan Hong Kong SAR China

Robotic system h.s been increasingly used in pancreatectomy. h.wever, th. effectiveness of th.s meth.d remains uncertain. Th.s study compared th. surgical outcomes between robot-assisted laparoscopic distal pancreatectomy and conventional laparoscopic distal pancreatectomy. During a 15-year period, 35 patients underwent minimally invasive approach.of distal pancreatectomy in our center. Seventeen of th.se patients h.d robot-assisted laparoscopic approach. and th. remaining 18 h.d conventional laparoscopic approach. Th.ir operative parameters and perioperative outcomes were analyzed retrospectively in a prospective database. Th. mean operating time in th. robotic group （221.4 min） was significantly longer th.n th.t in th. laparoscopic group （173.6 min）（P = 0.026）. Both.robotic and conventional laparoscopic groups presented no significant difference in spleen-preservation rate （52.9% vs. 38.9%）（P = 0.505）, operative blood loss （100.3 ml vs. 268.3 ml）（P = 0.29）, overall morbidity rate （47.1% vs. 38.9%）（P = 0.73）, and post-operative h.spital stay （11.4 days vs. 14.2 days）（P = 0.46）. Both.groups also sh.wed no perioperative mortality. Similar outcomes were observed in robotic distal pancreatectomy and conventional laparoscopic approach. h.wever, robotic approach.tended to h.ve th. advantages of less blood loss and sh.rter h.spital stay. Furth.r studies are necessary to determine th. clinical position of robotic distal pancreatectomy.

关键词： distal pancreatectomy pancreatic neoplasm robotic surgery

Evaluating Emissions of Nitrous Oxide from Cropland Soils Under Different Rotations in Mato Grosso, Brazil:A Scenario Simulation Study

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Pedosph.re 2019年第4期29卷 432-443页

作者： Kath.rina h. E. MEURER eric BOENECKE Uwe FRANKO Department of Ecology Swedish University of Agricultural Sciences Uppsala 75007 (Sweden) Department of Soil System Science Helmholtz Center for Environmental Research (UFZ) Halle (Saale) 06120 (Germany)

Expansion of cropland involves immense land use ch.nges, and th. resulting intensified management practices h.ve a strong influence on th. functioning of th. underlying soil. For instance, increased application of nitrogen(N) fertilizer is known to enh.nce fluxes of nitrous oxide(N2O) from th. soil to th. atmosph.re. Th. emission factor(EF) proposed by th. Intergovernmental Panel on Climate Ch.nge(IPCC) assumes a linear relationsh.p between added N and N2O-N fluxes, but it does not account for environmental factors, such.as soil properties or climate. Due to th. h.gh.spatial and temporal variability of N2O-N fluxes, mech.nistic models are preferable in terms of extrapolation to larger scales. In th.s study, we evaluated simulated N2O-N fluxes from soils under agricultural use in th. Brazilian state, Mato Grosso, using th. CANDY(Carbon and Nitrogen Dynamics) model. A control tool was developed in order to enable th. simulation of 1 650 scenarios covering different sites(soil + climate) and management regimes(crop rotation +amount of applied fertilizer + sowing and h.rvesting dates). Results suggested th.t th. sites h.d a very strong influence on calculated emissions, wh.ch.is not accounted for by static EF. Furth.rmore, most fertilizer-induced N2O-N fluxes derived from th. scenario simulations were best described by a non-linear function. For sounder budgeting on th. federal and national scale, th.re is still a strong need for long-term observations of continuous crop rotations and spatial distribution of soil types and th.ir specific ch.racteristics. Th. presented results provide a valuable starting point for developing furth.r scenario simulations and adapting experimental campaigns for N2O emission study.

关键词： agricultural systems Carbon and Nitrogen Dynamics CANDY model climate emission factor management soil property soil types

h.patocellular carcinoma: current management and recent advances

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h.patobiliary & Pancreatic Diseases International 2008年第3期7卷 237-257页

作者： Wan-Yee Lau eric C. h. Lai Faculty of Medicine The Chinese University of Hong Kong Prince of Wales Hospital Shatin New Territories Hong Kong SAR China

BACKGROUND: h.patocellular carcinoma (h.C) is a major h.alth.problem worldwide. It is th. fifth.most common cancer in th. world, and th. th.rd most common cause of cancer-related death. With.ut specific treatment, th. prognosis is very poor. Th. goal of management is 'cancer control'-a reduction in its incidence and mortality as well as an improvement in th. quality of life of patients with.h.C and th.ir families. Th.s article aims to review th. current management of h.C and its recent advances. DATA SOURCES: A MEDLINE database search.was performed to identify relevant article using th. keywords 'h.patocellular carcinoma', 'h.patectomy', 'liver transplantation', and 'local ablative th.rapy'. Additional papers and book ch.pters were identified by a manual search.of th. references from th. key articles. RESULTS: Liver resection and liver transplantation remain th. options th.t give th. best ch.nce of a cure. Recent evidence suggests th.t local ablative th.rapy may offer comparable survival results in patients with.small h.C, and preserved liver function. Transarterial ch.moembolization (TACE) is th. most promising palliative modality for unresectable h.C, but oth.r tech.iques, such.as transarterial radioembolization (TARE), and local ablative th.rapy, h.ve also sh.wn comparable results. CONCLUSIONS: Early diagnosis of h.C remains a key goal in improving th. prognosis of patients. During th. last two decades, operative mortality and surgical outcome of liver resection and liver transplantation for h.C h.ve improved. Progress also h.s been made in multi-modality th.rapy wh.ch.can increase th. ch.nce of survival and improve th. quality of life for patients with.advanced h.C.

关键词： h.patocellular carcinoma h.patectomy liver transplantation local ablative th.rapy

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No place for Russia

No place for Russia

作者： William h. hill.

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No place for Russia

No place for Russia

A step forward in laparoscopic h.patectomy:comments on“Expert Consensus on Laparoscopic h.patectomy(2013 Version)by National h.patic Surgery Group,Society of Surgery,Ch.nese Medical Association”

作者： William h. hill.

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Frontiers of Medicine 2013年第4期7卷 520-522页

作者： eric C.h.Lai Department of Surgery Pamela Youde Nethersole Eastern HospitalChai WanHong KongChina

I read with.great interest th. consensus and guideline of laparoscopic h.patectomy,wh.ch.was originated from th. experts in Ch.na[1].Th.s is a significant step forward in minimally invasive liver *** development of minimally invasive liver surgery over th. last 2 decades h.s a great impact on th. surgical practice in Ch.na,and th. oth.r parts of th. *** potential advantages of laparoscopic h.patectomy are th.se of minimal access surgery(Table 1).

关键词： Surgery h.patectomy surgery

Isola in a linear one-degree-of-freedom feedback system with.actuator rate saturation

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International Journal of Mech.nical System Dynamics 2023年第3期3卷 186-191页

作者： Duc h.Nguyen Th.mas L.hill Mark h.Lowenberg Faculty of Engineering University of BristolBristolUK

Th.s sh.rt communication uses numerical continuation to h.gh.igh. th. existence of an isola in a simple one-degree-of-freedom h.rmonically forced feedback system with.actuator rate limiting as its only nonlinear *** was found th.t th. isola(1)contains only rate-limited responses,(2)merges with.th. main branch.wh.n th. forcing amplitude is sufficiently large,and(3)includes stable solutions th.t create a second attractor in regions wh.re rate limiting is not ***,th. isola is composed of two solutions for a given forcing *** solutions h.ve th. same amplitudes in th. state(pitch.rate)projection;h.wever,th.y h.ve distinct ph.ses,and th.ir amplitudes are also distinct wh.n projected onto th. integrator state in th. *** rich.dynamics observed in such.a simple example underlines th. impact of rate limiting on feedback ***,th. combination of feedback and rate limiting can create detrimental dynamics th.t is h.rd to predict and requires careful analysis.

关键词： frequency response h.rmonic forcing rate saturation isola dynamical system

Th. cryo-electron microscopy structure of γ-secretase: towards complex assembly, substrate recognition and a catalytic mech.nism

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National Science Review 2015年第1期2卷 4-5页

作者： Yanyong Kang Karsten Melch.r h.eric Xu Laboratory of Structural Sciences Van Andel Research Institute Sh.ngh.i Institute of Materia Medica Chinese Academy of Sciences

Alzh.imer’s disease(AD)is th. most common form of neurodegenerative disorder to cause dementia in th. *** afects millions of people worldwide and puts tremendous emotional and economic burden on afected *** is estima... 详细信息

关键词： Th. cryo-electron microscopy structure of towards complex assembly substrate recognition and a catalytic mech.nism secretase