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Lung cancer management during the COVID-19 pandemic:experience of a medical oncology unit at a tertiary hospital in Singapore

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Journal of Cancer Metastasis and Treatment 2020年第1期6卷 707-717页

作者： Elise Ky Vong Puey-Ling Chia Alex y.chang Department of Medical Oncology Tan Tock Seng HospitalSingapore Lee Kong Chian School of Medicine Singapore Johns Hopkins University School of Medicine BaltimoreMD 21836USA

Coronavirus disease 2019(COVID-19),caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),was declared a pandemic by the World Health Organisation(WHO)on 11 March *** pandemic has had profound effects on healthcare systems across the world,and also poses unique challenges for oncology *** saw its first imported case of COVID-19 on 23 January 2020,and there has since been 52,000 confirmed cases and 27 deaths as of early August 2020 *** have a special duty to our patients to ensure patient safety and provide optimum care without undue disruption which may compromise long-term cancer-specific *** herein examine the impact that the COVID-19 pandemic has had on our clinical services,and share our experience with regards to manpower reconfiguration,infection control measures,diagnostic evaluation of patients with suspected COVID-19,oncological management of lung cancer patients,as well as changes in the education and training of juniors,from our unique position as a Medical Oncology department in Tan Tock Seng Hospital,a tertiary hospital affiliated with the National Centre of Infectious Diseases in Singapore.

关键词： COVID-19 lung cancer thoracic cancer

美国放射学院适宜性标准:肩关节置换术后影像学检查(续)

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中华肩肘外科电子杂志 2017年第4期5卷 299-304页

作者：张晓萌陈建海 Soterios Gyftopoulos Zehava S.Rosenberg Catherine C.Roberts Jenny T.Bencardino Marc Appel Steven J.Baccei R.Carter Cassidy eric y.chang Michael G.Fox Bennett S.Greenspan Mary G.Hochman Jon A.Jacobson Douglas N.Mintz Joel S.Newman Nehal A.Shah Kirstin M.Small Barbara N.Weissman 北京大学人民医院创伤骨科 100044 纽约大学医疗中心纽约市纽约关节病医院纽约市梅奥诊所亚利桑那州凤凰城纽约大学医学院纽约市 James J.Peters VA医疗中心纽约市马萨诸塞大学医疗中心伍斯特英国医疗脊柱和全关节服务列克星敦 VA圣地亚哥医疗系统圣地亚哥弗吉尼亚卫生系统夏洛茨维尔奥古斯塔大学佐治亚州医学院奥古斯塔贝斯以色列女执事医疗中心波士顿密歇根大学医疗中心安娜堡纽约特种外科医院纽约市新英格兰浸信会医院波士顿布列根和妇女医院波士顿

过去的20年里,在美国实施的肩关节置换术的数量迅速增长,其中包括部分或全肱骨头表面置换术、半肩置换术、全肩关节置换术和反式全肩关节置换术。影像学检查在诊断这些肩关节置换术引起的并发症方面起到了重要作用。本综述分为两个部分... 详细信息

过去的20年里,在美国实施的肩关节置换术的数量迅速增长,其中包括部分或全肱骨头表面置换术、半肩置换术、全肩关节置换术和反式全肩关节置换术。影像学检查在诊断这些肩关节置换术引起的并发症方面起到了重要作用。本综述分为两个部分。第一部分阐述了对各种影像学检查模式的总体探讨,包括X线片、计算机断层扫描、核磁共振成像、超声、核医学以及它们提供有益的以治疗为导向的信息时所发挥的作用。第二部分重点研究最佳影像学方法的选择,用于肩关节置换术的并发症,包括无菌性松动、感染、骨折、肩袖肌腱撕裂和神经损伤。在本报告中所提供的美国放射学院适宜性标准循证指南,是通过广泛分析来自同行评审期刊的现有医学文献,并应用行之有效的方法学而完成的(兰德/加州大学洛杉矶分校的适宜性方法以及推荐评价、发展和评估分级),它们用于特殊临床情况下的影像学检查和治疗措施的适宜性评价。多学科专家小组对指南进行了进一步的分析和审查。由于用于推荐合适成像算法的数据会出现不足或模棱两可,在这种情况下,专家意见可能对现有证据进行补充。为此,将美国《放射学院适宜性标准:肩关节置换术后影像学检查》翻译成中文,供同道参考。

关键词：全肩关节置换术美国放射学院影像学检查适宜性标准核磁共振成像计算机断层扫描循证指南

Study on the Synthesis and Adsorption Properties of KH-560 Modified PalygorskiteSupported β-Cyclodextrin

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复旦学报（自然科学版） 2007年第5期46卷 788-,791页

作者： D.M.ZHU L.yAN X.L.SHI y.chang Key Laboratory of Polymer Materials of Gansu Province College of Chemistry and Chemical EngineeringNorthwest Normal University

1 Results Palygorskite (PGS) is a chain-layer magnesium-aluminum silicate mineral. Because of its developed interior channels and large specific surface area, and thus considerable adsorption capacity, it has been studied for the application as one of environmental mineral adsorbents[1-3]. Cyclodextrins (CD) possess a hydrophilic exterior and a hydrophobic interior into which a variety of hydrophobic organic molecules maybe introduced. The CD molecule not only affects a hydrophilic cavity on the nanomet...

关键词： KH-560 modified palygorskite β-cyclodextrin adsorption phenolic compounds

Spectral Aspects of the Skew-Shift Operator:A Numerical Perspective

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Communications in Computational Physics 2014年第3期15卷 712-732页

作者： eric Bourgain-chang Mechanical Engineering Department University of CaliforniaBerkeleyCA 94720USA

In this paper we perform a numerical study of the spectra,eigenstates,and Lyapunov exponents of the skew-shift counterpart to Harper’s *** study is motivated by various conjectures on the spectral theory of these’pseudo-random’models,which are reviewed in detail in the initial sections of the *** numerics carried out at different scales are within agreement with the conjectures and show a striking difference compared with the spectral features of the Almost Mathieu *** particular our numerics establish a small upper bound on the gaps in the spectrum(conjectured to be absent).

关键词： Schrödinger operator skew-shift spectrum localization

Determination of Aminoglycosides by Capillary Electrophoresis with Laser-induced Fluorescence Detection

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Determination of Aminoglycosides by Capillary Electrophoresi...

Congenital penile curvature: long-term results of operative treatment using the plication procedure

第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会

作者： Sarah y.chang yi-Fung Lin Department of Chemistry Tunghai University Taichung Taiwan Department of Chemistry Tunghai University Taichung Taiwan

Capillary electrophoresis (CE) is a useful technique to quantify drugs in biological fluids. Due to short optical length of CE, the sensitivity is not sufficient to quantify drugs in biological samples as they often need to be quantified in the lower μg/L range. A sensitive analytical method for aminoglycosides based on capillary electrophoretic separation and laser-induced fluorescence (LIF) has been developed. 6-Carboxyfluorescein succinimidyl ester (CFSE) was used

关键词： Determination of Aminoglycosides by Capillary Electrophoresis with Laser-induced Fluorescence Detection

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Asian Journal of Andrology 2004年第3期6卷 273-276页

作者： S.-S.Lee E.Meng F.-P.Chuang C.-y.yen S.-y.chang D.-S.yu G.-H.Sun Division of Urology Department of SurgeryTri-Service General HospitalNational Defense Medical CenterNationalDefense UniversityTaipeiChina

Aim: To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. Methods: From January 1992 to January 2002, 106 young patients underwent surgical correction of congenital penile curvature by corporeal plication. Indications for operation were difficult or impossible vaginal penetration and cosmetic problems. The technique of corporeal plication consists of placing longitudinal plication sutures of 2-zero braided polyester on the convex side of the curvature until the curvature is corrected when erection is artificially induced. Results of this procedure were obtained by retrospective chart reviews and questionnaires via mail. Long-term follow-up ranged from 11 to 132 (mean 69.3) months and data were available for 68 patients. Results: Penile straightening was excellent in 62 patients (91 %) and good with less than 15 degree of residual curvature in 6 patients (9 %). Sixty-seven patients reported no change in erectile rigidity or maintenance postoperatively, while 1 described early detumescence. Shortening of the penis without functional problems was noted by 26 patients (38 %). Thirty-Five patients (51 %) reported feeling palpable indurations (suture knots) on the penis. Temporary numbness of glans penis was described in 3 patients. Overall, 60 patients were very satisfied, 6 satisfied, 2 unsatisfied. Conclusion: Corporeal plication is an effective and durable procedure with a high rate of patient satisfaction.

关键词： penile curvature treatment plication procedure

Experimental Hamiltonian Learning of an 11-Qubit Solid-State Quantum Spin Register

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Chinese Physics Letters 2019年第10期36卷 11-16页

作者： P.-y.Hou L.He F.Wang X.-Z.Huang W.-G.Zhang X.-L.Ouyang X.Wang W.-Q.Lian X.-y.chang L.-M.Duan Center for Quantum Information Institute for Interdisciplinary Information SciencesTsinghua UniversityBeijing 100084

Learning the Hamiltonian of a quantum system is indispensable for prediction of the system dynamics and realization of high fidelity quantum ***,it is a significant challenge to efficiently characterize the Hamiltonian which has a Hilbert space dimension exponentially growing with the system ***,we develop and implement an adaptive method to learn the effective Hamiltonian of an 11-qubit quantum system consisting of one electron spin and ten nuclear spins associated with a single nitrogen-vacancy center in a *** validate the estimated Hamiltonian by designing universal quantum gates based on the learnt Hamiltonian and implementing these gates in the *** experimental result demonstrates a well-characterized 11-qubit quantum spin register with the ability to test quantum algorithms,and shows our Hamiltonian learning method as a useful tool for characterizing the Hamiltonian of the nodes in a quantum network with solid-state spin qubits.

关键词： Hamiltonian quantum system

Tuning periodicity of polymer-decorated carbon nanotubes

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Science China Chemistry 2012年第5期55卷 802-807页

作者： LAIRD eric D. LI Christopher y. A. J. Drexel Nanotechnology Institute and Department of Materials Science and Engineering Drexel University Philadelphia Pennsylvania 19104 USA

Carbon nanotube (CNT) is one of the most extensively investigated nanomaterials. Patterning soft matter such as liquid crystals and polymers on CNTs could potentially enable various applications for CNTs. We have demonstrated that controlled polymer crystallization using CNTs as the 1D nucleation sites can lead to periodically functionalized CNTs. Here we show that selected crystalline block copolymers can be periodically decorated along CNTs. This facile technique opens a gateway to periodic patterning on 1-D nanomaterials.

关键词： polymer crystallization carbon nanotube block copolymers

Proton therapy in clinical practice

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Chinese Journal of Cancer 2011年第5期30卷 315-326页

作者： Hui Liu Joe y. chang Sun yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China Radiation Oncology Department University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Radiation dose escalation and acceleration improves local control but also increases *** radiation is an emerging therapy for localized cancers that is being sought with increasing frequency by *** with photon therapy,proton therapy spares more critical structures due to its unique *** physical properties of a proton beam make it ideal for clinical *** modulating the Bragg peak of protons in energy and time,a conformal radiation dose with or without intensity modulation can be delivered to the target while sparing the surrounding normal ***,proton therapy is ideal when organ preservation is a ***,protons are more sensitive to organ motion and anatomy.changes compared with *** this article,we review practical issues of proton therapy,describe its image-guided treatment planning and delivery,discuss clinical outcome for cancer patients,and suggest challenges and the future development of proton therapy.

关键词：质子束临床实践治疗 Bragg峰辐射剂量物理特性局部控制癌症病人