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Epidemiological Profile of Pet Bites and Rabies Cases from 2005-2015: Case of the City of Lubumbashi in the DRC

Open Journal of Veterinary Medicine 2022年第3期12卷 19-26页

作者： Nathalie Nseya André Ngombe Kaseba Charles Muhadila Jean Claude Mbang Claude Yav Ghislain Kikunda Augustin Mutombo Mulangu Philippe Mulenga Cilundika Oscar Luboya Numbi eric mukomena sompwe Ministry of Public Health Hygiene and Prevention Vaccinogenic Office of Lubumbashi Lubumbashi Democratic Republic of the Congo Schoolof Public Health University of Lubumbashi Lubumbashi Democratic Republic of the Congo Higher Institute of Agronomic and Veterinary Studies of Sandoa Kolwezi Democratic Republic of the Congo University of Lubumbashi Faculty of Medicine Lubumbashi Democratic Republic of the Congo

Introduction: Rabies, a neglected disease, could be grossly underreported in the DRC;in the absence of post-exposure prophylaxis, the WHO estimates that this disease would cause 327,000 deaths per year in Africa and Asia. The objective of this study is to determine the epidemiological profile of this zoonosis in order to encourage decision-makers to develop national strategies for its elimination. Materials and Methods: We conducted a cross-sectional descriptive study. Data collection was done retrospectively and in total6 420 victims of bites received during the period between January 2005 and December 2015 at the anti-rabies center in Lubumbashi were included in this work. Excel 13 software and Epi info 3.3.4 were used for data analysis and interpretation. Results: People over the age of 15 are the main victims of canine bites (62.1%), more than half of the victims are male (55.9%);dogs represent the majority of biting animals (96.4%) of which around 3/4 are unvaccinated (71.37%). Two municipalities are more affected: Lubumbashi (prevalence 83.35/100,000 and Kampemba (Prevalence 51.74/100,000). LBite peaks were observed from July to October (p = 0.01). For the 34 people seen with clinical signs of rabies encephalitis (confirmed case of rabies), the case fatality rate was 100%. Conclusion: Rabies is a major problem in Lubumbashi but its extent is different depending on the municipality. The dog is the main biting animal and the vaccination coverage of dogs remains very low. Access to rabies vaccine for bite victims is difficult. Its elimination remains possible through the implementation of an extensive canine vaccination program, the awareness of owners and the large-scale provision of post-exposure prophylaxis.

关键词： Epidemiology Bites Rabies Lubumbashi

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Occupational Hearing Hazards among Informal Sector Welders in Lubumbashi, Democratic Republic of Congo

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Health 2021年第9期13卷 995-1009页

作者： Nowa Mutangala Mor Ndiaye André Ngombe Kaseba Clarence Mukeng Philippe Mulenga Cilundika eric sompwe mukomena Ruashi Mining Lubumbashi Democratic Republic of Congo (DRC) Occupational Medicine Service Faculty of Medicine University Cheikh Anta Diop (UCAD) Dakar Senegal School of Public Health University of Lubumbashi Lubumbashi Democratic Republic of Congo Department of Public Health School of Medicine University of Lubumbashi Lubumbashi Democratic Republic of Congo

Introduction: Noise, an undesirable sound which is found in all areas of occupational activity, is still a matter of concern given the damage it causes. Various machines and tools, from simple to sophisticated ones, produce several types of noise in the workplace. The purpose of this study was to assess the current status of occupational hearing loss among informal sector welders in the city of Lubumbashi, in the Democratic Republic of Congo. Methods: This was a descriptive cross-sectional study which was conducted among 122 informal sector welders over a period of five months. The study used an anonymous questionnaire on noise exposure in the workplace and collected audio-metric data of welders. The survey collected data on welders who had a minimal three-year duration of employment without the morbidity associated with the Ear Nose Throat (ENT) region. Socio-professional data (age, duration of employment, sex, education), noise exposure, awareness of hazards and audiometric data were taken into account. Results: 122 questionnaires were completed by male subjects, or 100% (n = 122). The mean age of welders was 36.37 ± 11.91 years with extremes being 20 and 63 years. The mean duration of employment was 11.51 ± 9.6 years with extremes being 3 and 44 years. Audiometric data have shown 37.96% (n = 41) of occupational hearing loss. Three degrees of hearing loss were recorded, notably mild hearing loss standing at 80.49% (n = 33);moderate and severe hearing loss standing at 2.44% (n = 1). Ninety-six percent (n = 117) of welders reported not using personal protective equipment (PPE) and 1% (n = 111) were aware of the hazard associated with noise exposure in the workplace. A correlation was found between welders with an advanced age (p Conclusion: In the study are

关键词： Audiometry Informal Sector Welders Lubumbashi DRC

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Mass Distribution Campaign of Long-Lasting Insecticidal Nets in the Democratic Republic of Congo from 2018 to 2021 in the Context of the Emergence of COVID-19: Results and Lessons Learned

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Journal of Biosciences and Medicines 2022年第2期10卷 136-159页

作者： Joris Losimba Likwela Adrien N’siala Kumbi Michèle Luntadila Kiamenga Mireille Lusiense Zena Daniela Mundele Iris Simon-Pierre Kazadi Mutuba eric mukomena sompwe Patrick Kanku-Ka-Lukusa Albert Kalonji Ntumba Ghislain Makhan Yav Didier Gasigwa Baneti eric Tsasa Mbuku Charlotte Ndolerire Isingoma Muriel Nzazi Nsambu Philippe Lukanu Ngwala SANRU Asbl Kinshasa Democratic Republic of the Congo Public Health Department Faculty of Medicine and Pharmacy University of Kisangani Kisangani Democratic Republic of the Congo National Malaria Control Program Kinshasa Democratic Republic of the Congo School of Public Health University of Lubumbashi Lubumbashi Democratic Republic of the Congo Financial Support and Management Unit Ministry of Public Health Prevention and Hygiene Kinshasa Democratic Republic of the Congo Interchuch Medical Assistance World Heath Kinshasa Democratic Republic of the Congo World Health Organisation Kinshasa Sub-Office Democratic Republic of the Congo Department of Family Medicine et Primary Health Care Protestant University of Congo Kinshasa Democratic Republic of the Congo

Introduction: The DRC had planned 23 mass distribution campaigns distribution of long-lasting insecticidal nets (LLIN) for the years 2018-2020, the implementation of which spanned from 2018 to July 2021. This article reviews the campaign’s planning process, the results, challenges, and lessons learned. Methods: A descriptive method was used to postpone the planning and implementation process according to the National Malaria Control Program (NMCP) standards adapted to the COVID-19 context. The changes and adaptations implemented as well as the challenges encountered are described. Results: Between January 2018 to June 2021, 23 LLIN mass distribution campaigns were organized in the DRC with the financial support of The Global Fund to Fight against Tuberculosis, AIDS and Malaria (GFTAM) and Against Malaria Foundation (AMF) allowing the distribution of 55,273,473 LLINs to 19,048,372 households at risk of malaria transmission with an average of 2.9 LLINs per household. The enumerated population (111,081,191) exceeded 7% of the micro plans projected population (102,790,391) while the number of households enumerated (19,311,629) was 3% lower compared to the micro planning projection households (19,862,417). Compared to a reported household coverage of 96% of households achieved over the expected households, the independent monitoring carried out revealed 91% of households served in the intervention areas. The main reasons for not reaching households mentioned by the respondents were absence at the time of distribution (26%) followed by the loss of vouchers (16%). Several communication channels were used among which, community workers were the most frequently mentioned (63.1%), followed by radios (18.5%) and churches (12.4%). Conclusion: Good planning, effective coordination of stakeholders, and revision of the implementing campaigns methods following the COVID-19 were factors in the success of this campaign. An effort to respect the schedules for renewing LLINs in househo

关键词： Vector Control LLIN Campaigns COVID-19 Lessons Democratic Republic of Congo

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Determinants and Knowledge on Geo-Helminthiasis in Prison Inmates: Case of Kassapa Central Prison, Lubumbashi, Democratic Republic of Congo

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Health 2021年第5期13卷 600-618页

作者： André Ngombe Kaseba Tshipapa Mujinga Aly Antoine Kamano Cissé Kadari Kikunda Ghislain Nowa Mutangala Philippe Mulenga-Cilundika eric mukomena sompwe School of Public Health University of Lubumbashi Lubumbashi Democratic Republic of Congo Faculty of Medicine University of Lubumbashi Lubumbashi Democratic Republic of Congo Ministry of Health Conakry Republic of Guinea Health Science Research Institute Ouagadougou Burkina Faso Ruashi Mining Lubumbashi Democratic Republic of Congo

Introduction: Geohelminths are infections due to various species of parasitic worms transmitted by eggs present in human excreta which contaminate the soil where sanitation is poor. The objective of this study was to analyse the determinants and knowledge on geo-helminthiasis among inmates and care providers in the Kassapa prison environment in Lubumbashi in the Demographic Republic of Congo. Methods: This is a cross-sectional descriptive study which was conducted from September 21 to October 15, 2020 in Kassapa prison in Demographic Republic of Congo. Estimates of the prevalence and general characteristics of geo-helminthiasis in prisoners were calculated by descriptive analyses. The analysis of determinants was performed based on a binary logistic regression. Results: With regard to the quantitative section, the study used a sample size of 1083 while a sample size of six was considered for the qualitative section. The annual prevalence of geo-helminthiasis was 10.2%, 4.8% and 2.9% respectively for 2017, 2018 and 2019. It was found that the general prevalence of geo-helminthiases was 17.9%. The age group above 39 years constitutes the modal class with 29.4%, the least affected age group being that of minors with 6.3%. The association is statistically significant between sex, treatment, prison residence and year. Thus, taking gender into account, women are by 2.3 (OR = 2.3, 95% CI [1.3%;4.8%], p value Conclusion: This descriptive cross-sectional study rounds off by pointing to poor hygiene, insufficient health education an

关键词： Determinants Knowledge Geo-Helminthiasis Prison Environment DRC

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Taxonomy,distribution,and contemporary exposure of terrestrial mammals to floods and human pressure across different areas for biodiversity conservation in China

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Integrative Zoology 2024年第3期19卷 458-467页

作者： Roman SHARNUUD eric I.AMECA MOE Key Laboratory for Biodiversity Science&Ecological Engineering College of Life SciencesBeijing Normal UniversityBeijingChina Climate Change Specialist Group Species Survival CommissionInternational Union for Conservation of NatureGlandSwitzerland

A significant research focus is placed on identifying animal species and areas at future risk to human-induced alterations of the environment and long-term changes in climatic ***,the extent to which exposure to extreme climatic events and intense human pressure can increase the risk of harmful impacts on species remains poorly *** on terrestrial mammals in China,one of the world’s megadiverse countries,we investigated patterns of contemporary exposure to floods and human pressures and determined their taxonomic representation and distribution across three major area-based conservation schemes,namely,national nature reserves(NNRs),priority areas for biodiversity conservation(PABCs),and key biodiversity areas(KBAs).Among the 440 species assessed with moderate or high exposure to floods,327(∼75%)also qualified as moderate or high in exposure to intense human *** species mainly belong to the orders Chiroptera,Eulipotyphla,and ***,there were 305,311,and 311 species with moderate or high exposure to flood and intense human pressure represented across NNRs,PABCs,and KBAs,*** findings support the prioritization of KBAs for expansion of site-based protection efforts such as NNRs in China,considering threats to species from exposure to adverse effects from both extreme climate and human pressure.

关键词： conservation floods human pressure mammals taxonomy

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Larval development and voracity of Eupeodes americanus (Diptera: Syrphidae): comparison of the focal prey Aphis gossypi (Hemiptera: Aphididae) and the banker prey Rhopalosiphum padi (Hemiptera: Aphididae)

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Insect Science 2024年第2期31卷 575-586页

作者： Arlette Fauteux Antonio Onofre Soares eric Lucas Laboratoire de lutte biologique Departement des sciences biologiquesUniversite du Quebec a Montreal(UQAM)MontrealQuebecCanada Faculty of Science and Technology Center for Ecology Evolution and Environmental ChangesAzorean Biodiversity Group(cE3c-ABG)&CHANGE-Global Change and Sustainability InstitutePonta DelgadaPortugal

Unlike European species,the potential of Nearctic syrphids as biological control agents is still poorly ***,the American hoverfly,Eupeodes americanus(Wiedemann),has recently demonstrated promising traits as a biocontrol agent,notably against the foxglove aphid,Aulacorthum solani Kaltenbach,on *** present study aims to extend our knowledge of the American hoverfly by evaluating its potential as a biocontrol agent in a banker plant system against the melon aphid,Aphis gossypi Glover,in a greenhouse cucumber *** preimaginal development and voracity of *** were compared when preying upon the focal prey/pest(***)or the banker prey(bird cherry-oat aphid,Rhopalosiphum padi L.)by daily observations of larvae from egg to *** development time,survival rate,and occurrence of deformation were similar on both prey *** weight of third instar and pupae,however,was higher for larvae that fed on the banker *** ad libitum voracity of the syrphid larvae was generally very high and did not significantly differ between prey species,except for the third-instar larvae which consumed more focal *** suggest that a banker plant system involving the bird cherry-oat aphid may be a promising tactic for utilizing *** for melon aphid biocontrol.

关键词： american hoverfly banker plant system biological control bird cherry-oat aphid greenhouse cucumber melon aphid

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Occupational Hearing Hazards among Informal Sector Welders in Lubumbashi, Democratic Republic of Congo

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Health 2021年第9期

作者： Nowa Mutangala Mor Ndiaye André Ngombe Kaseba Clarence Mukeng Philippe Mulenga Cilundika eric sompwe mukomena

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Opto-fluidically multiplexed assembly and micro-robotics

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Light(Science & Applications) 2024年第3期13卷 544-554页

作者： Elena Erben Weida Liao Antonio Minopoli Nicola Maghelli eric Lauga Moritz Kreysing Max Planck Institute of Molecular Cell Biology and Genetics Dresden 01307Germany Center for Systems Biology Dresden 01307Germany Institute of Biological and Chemical Systems–Biological Information Processing.Karlsruhe Institute of Technology(KIT) Eggenstein-Leopoldshafen 76344Germany Department of Applied Mathematics and Theoretical Physics University of CambridgeCambridge CB30WAUK

Techniques for high-definition micromanipulations,such as optical tweezers,hold substantial interest across a wide range of ***,their applicability remains constrained by material properties and laser *** while microfluidic manipulations have been suggested as an alternative,their inherent capabilities are limited and further hindered by practical challenges of implementation and *** we show that the iterative application of laser-induced,localized flow fields can be used for the relative positioning of multiple micro-particles,irrespectively of their material *** to the standing theoretical proposal,our method keeps particles mobile,and we show that their precision manipulation is non-linearly accelerated via the multiplexing of temperature stimuli below the heat diffusion *** resulting flow fields are topologically rich and mathematically *** represent unprecedented microfluidic control capabilities that are illustrated by the actuation of humanoid micro-robots with up to 30 degrees of freedom,whose motions are sufficiently well-defined to reliably communicate personal characteristics such as gender,happiness and *** results constitute high-definition micro-fluidic manipulations with transformative potential for assembly,micro-manufacturing,the life sciences,robotics and optohydraulically actuated micro-factories.

关键词： manipulation fluid assembly

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Exploring the modulatory role of bovine lactoferrin on the microbiome and the immune response in healthy and Shiga toxin‑producing *** challenged weaned piglets

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1278-1291页

作者： Matthias Dierick Ruben Ongena Daisy Vanrompay Bert Devriendt eric Cox Laboratory of Immunology Department of Translational PhysiologyInfectiology and Public HealthFaculty of Veterinary MedicineGhent UniversitySalisburylaan 1339820 MerelbekeBelgium Laboratory for Immunology and Animal Biotechnology Faculty of Bioscience EngineeringGhent UniversityCoupure links 6539000 GhentBelgium

Background Post-weaned piglets suffer from F18+Escherichia coli(***)infections resulting in post-weaning diar-rhoea or oedema *** used management strategies,including colistin and zinc oxide,have contrib-uted to the emergence and spread of antimicrobial *** antimicrobials capable of directly interacting with pathogens and modulating the host immune responses are being *** has shown promising results against porcine enterotoxigenic *** strains,both in vitro and in *** We investigated the influence of bovine lactoferrin(bLF)on the microbiome of healthy and infected weaned ***,we assessed whether bLF influenced the immune responses upon Shiga toxin-producing ***(STEC)***,2 in vivo trials were conducted:a microbiome trial and a challenge infection trial,using an F18+STEC *** did not affect theα-andβ-***,bLF groups showed a higher relative abundance(RA)for the Actinobacteria phylum and the Bifidobacterium genus in the ileal *** analysing the immune response upon infection,the STEC group exhibited a significant increase in F18-specific IgG serum levels,whereas this response was absent in the bLF *** Taken together,the oral administration of bLF did not have a notable impact on theα-andβ-diversity of the gut microbiome in weaned ***,it did increase the RA of the Actinobacteria phylum and Bifi-dobacterium genus,which have previously been shown to play an important role in maintaining gut ***,bLF administration during STEC infection resulted in the absence of F18-specific serum IgG responses.

关键词： E.coli Immune modulation Lactoferrin Microbiome

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Untangling the biotic stress in the late Maastrichtian Deccan-benchmark interval of Bidart(France)

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Journal of Palaeogeography 2024年第2期13卷 181-198页

作者： Subham Patra Gerta Keller eric Font Thierry Adatte Jahnavi Punekar Indian Institute of Technology Bombay PowaiMumbai 400076India Princeton University PrincetonNJ 08544USA Departamento de Ciencias da Terra Faculdade de Ciencias e TecnologiaUniversidade de Coimbra3000-272 CoimbraPortugal Institute of Earth Sciences University of Lausanne1015 LausanneSwitzerland

The late Maastrichtian witnessed substantial surges in Deccan volcanism,prompting the hypothesis that these voluminous pulses may have instigated repeated episodes of ocean acidification during this *** Cretaceous-Palaeogene(K/Pg)boundary at Bidart(France)is preceded by a~0.5 m thick interval with geochemical and taphonomic vestiges of an ocean acidification event linked with Deccan *** planktic foraminifera census and morphometric data now confirm biotic stress conditions related to acidification in the Deccan benchmark *** absolute abundance data of larger(>150μm)heavily calcified planktic morphogroups show fluctuating populations throughout zone CF1(spanning the final~225 ky),lowest peaks within the Deccan benchmark,and a demographic collapse(>90%)at the K/Pg *** analyzed species are generally reduced in size,with thinner test walls in this~0.5 m interval,indicating the likelihood of calcification stress as a contributor to the overall biotic *** the K/Pg boundary,maximum biotic stress is recorded in all the tested faunal proxies.A preliminary graphic correlation of zone CF1 at Bidart with the auxiliary GSSP at Elles(Tunisia)constrains the Deccan benchmark interval of high biotic stress to the final~58ky of the late Maastrichtian,culminating in the K/Pg mass *** volcanogenic Hg peaks coincident with faunal and taphonomic evidence of ocean acidification strengthen the Deccan-related ocean acidification hypothesis.

关键词： Deccan volcanism K/Pg mass extinction Biotic stress Calcification stress

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