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Predictive factors for compliance with transanal irrigation for the treatment of defecation disorders

World Journal of Gastroenterology 2017年第11期23卷 2029-2036页

作者： Clémence Bildstein ChloéMelchior Guillaume Gourcerol Estelle Boueyre valérie Bridoux eric vérin Anne-Marie Leroi INSERM U1073 Service de Physiologie DigestiveCHU Rouen INSERM U1073 Service de Chirurgie DigestiveCHU Rouen EA 3830 Pole 3RCHU RouenGroupe de Recherche sur le Handicap Ventilatoire INSERM CIC 0204

AIM To investigate compliance with transanal irrigation(TAI) one year after a training session and to identify predictive factors for *** The compliance of one hundred eight patients [87 women and 21 men; median age 55 years(range 18-83)] suffering from constipation or fecal incontinence(FI) was retrospectively assessed. The patients were trained in TAI over a four-year period at a single institution. They were classified as adopters if they continued using TAI for at least one year after beginning the treatment or as non-adopters if they stopped. Predictive factors of compliance with TAI were based on pretreatment assessments and trainingprogress. The outcomes of the entire cohort of patients who had been recruited for the TAI treatment were expressed in terms of *** Forty-six of the 108(43%) trained patients continued to use TAI one year after their training session. The patients with FI had the best results, with 54.5% remaining compliant with TAI. Only one-third of the patients who complained of slow transit constipation or obstructed defecation syndrome continued TAI. There was an overall discontinuation rate of 57%. The most common reason for discontinuing TAI was the lack of efficacy(41%). However, 36% of the patients who discontinued TAI gave reasons independent of the efficacy of the treatment such as technical problems(catheter expulsion, rectal balloon bursting, instilled water leakage or retention, pain during irrigation, anal bleeding, anal fissure) while 23% said that there were too many constraints. Of the patients who reported discontinuing TAI, the only predictive factor was the progress of the training(OR = 4.9, 1.3-18.9, P = 0.02).CONCLUSION The progress of the training session was the only factor that predicted patient compliance with TAI.

关键词： Neurogenic bowel dysfunction Fecal incontinence Constipation Obstructed defecation Transanal irrigation

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Telomeric impact of conventional chemotherapy

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Frontiers of Medicine 2013年第4期7卷 411-417页

作者： Yiming Lu Waiian Leong Olivier Guérin eric Gilson Jing Ye Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200025China Institut for Research on Cancer and Aging Nice(IRCAN)Nice UniversityCNRS UMR7284/INSERM U1081Faculty of MedicineNiceFrance Geriatric Unit Cimiez HospitalCHU of NiceFrance Department of Medical Genetics Archet 2 HospitalCHU of NiceFrance

The increased level of chromosome instability in cancer cells,leading to aneuploidy and gross chromosomal rearrangements,is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies(CT)kill cells by inducing a non-tolerable rate of DNA damage.A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic *** results raise the interesting possibility that CT with genotoxic drugs preferentially target *** agreement with this view,accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT(stem cell transplantation)or non-myeloablative ***,almost nothing is known on the consequences of this shortening in terms of telomere stability,senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors(cognitive defect,fertility impairment,etc.).In this article,we propose:(1)telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance;(2)telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity;(3)the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.

关键词： telomere antineoplasic drugs conventional chemotherapies

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Choice of suitable regional and residual gravity maps, the case of the South-West Cameroon zone

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Earth and Planetary Physics 2019年第1期3卷 26-32页

作者： Fidèle Koumetio Donatien Njomo Constant Tatchum Noutchogwe eric Ndoh Ndikum Sévérin Nguiya Alain-Pierre Kamga Tokam Department of Physics Faculty of Science University of Dschang Department of Physics Faculty of Science University of Yaounde I Department of Physics ENS Bambili University of Bamenda Department of Fundamental Sciences H.T.T.T.C.Bambili-Bamenda University of Bamenda Department of Physics Faculty of Genial Engineering University of Douala

The quantitative interpretation of gravity anomalies due to shallow structures needs separation between long wavelength anomalies(regional anomalies) and short wavelength anomalies(residual anomalies).The regional-residual field separation can be carried out using the polynomial *** this case, the so-called regional field of order n is treated as a polynomial of degree *** present study shows that the degree n must vary between a smallest value n_(min) and a maximum value n_(max).This article presents a method to process gravity data that allows determination of n_(min) and n_(max) for a given study *** apply the method to gravity data of the South-West Cameroon *** this chosen study area, we find that regional anomaly maps of orders ranging from 1 to 9 and residual anomaly maps of orders ranging from 1 to 8 can be used for suitable *** analyses show that one may need residual anomaly maps of several orders to perform satisfactory quantitative interpretation of the different intrusive bodies found in a given area.

关键词： gravity regional anomaly residual anomaly upward continuation correlation factors intrusive body

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Who is at risk in the French mountains? Profiles of the accident victims in outdoor sports and mountain recreation

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Journal of Mountain Science 2017年第8期14卷 1490-1499页

作者： SOULE Bastien REYNIER véronique LEFEvRE Brice BOUTROY eric Laboratory of vulnerabilities & Innovation in Sport University Claude Bernard Lyon 1 Laboratory Sport & Social Environment University Grenoble Alpes

The risk of both severe and frequent injury associated with active pursuits in mountain areas is acknowledged. This phenomenon is all the most relevant to investigate in France that there is a growing enthusiasm for outdoor sports and recreation. This paper focuses on the social-demographic and sporting profiles of accident victims. Our intent is to better understand who is specifically at risk, while practicing mountain recreation, in the French mountains. Such identification doubtlessly constitutes an important asset in order to enhance prevention. Three critical activities are notably tackled, among some others: hiking, a widespread activity that exposes many practitioners to hazardous settings; mountaineering and ski touring, supposedly entailing the most severe *** order to align the information collected, then provide estimations based on the reasoned crossing of these secondary data, we consulted and summarised all the databases that we knew of on the French territory: rescue team intervention reports, aggregated statistics from the sports ministry, sporting federation accident declarations, avalanche experts statistics, mountain guides union accident/incident reports, healthcare facilities admissions, etc. Only the sources consideredto be the most reliable and representative were used, owing to the number of cases processed, the exhaustive nature of data collection, or the level of information detail available. Our method also included consultation of all the parties playing an active role in prevention, training and mountain rescue, thus ensuring a participative, co-constructive approach to the study with the people that have the best knowledge of victim profiles. Around fifty such parties were interviewed on the methods implemented, the benefits and limits of current data, and the main expectations in terms of accidentology progress, thus further enhancing the credibility of the study proposed in this paper. Our results show that the parent populat

关键词： Mountain sports Outdoor recreation Accident victims profile

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High efficiency GHz laser processing with long bursts

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International Journal of Extreme Manufacturing 2023年第1期5卷 202-210页

作者： eric Audouard eric Mottay Amplitude PessacFrance

Bursts of GHz repetition rate pulses involve more ablation mechanisms than single femtosecond *** ablation by GHz laser pulses is a multi-step process,consisting of a first thermal incubation phase,followed by a highly efficient ablation *** ablation therefore combines thermal and non-thermal ablation *** an optimal choice of the burst duration,the ablation efficiency can be highly *** bursts,comprising tens of pulses to hundreds of pulses,are needed to take full advantage of the increase in ablation efficiency.

关键词： femtosecond laser temporal pulses shaping GHz bursts femtosecond processing

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Current perspectives into the evaluation and management of hepatitis B: a review

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Hepatobiliary Surgery and Nutrition 2019年第4期8卷 361-369页

作者： vignan Manne eric Gochanour Kris v. Kowdley Liver Care Network Swedish Medical Center Seattle WA USA

Hepatitis B is a widespread disease which affects millions of people worldwide. Chronic hepatitis B (CHB) can lead to significant morbidity and mortality due to complications such as cirrhosis and hepatocellular carcinoma. The pathophysiology of hepatitis is critical to diagnosing CHB. Deciding which patients with CHB should be treated is an important decision as treatment can often lead to better outcomes in the appropriate patient population. The nucleos(t)ide analog inhibitors entecavir and tenofovir are currently the mainstay of treatment as they are able to successfully suppress the virus and lead to fewer complications. Novel therapies are currently being developed which may offer a potential cure for this disease in the future.

关键词： Chronic hepatitis B (CHB) hepatocellular carcinoma (HCC) tenofovir entecavir

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Artificial urinary sphincter surgery in the special populations:neurological,revision,concurrent penile prosthesis and female stress urinary incontinence groups

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Asian Journal of Andrology 2020年第1期22卷 45-50页

作者： eric Chung AndroUrology Centre BrisbaneQLD 4000Australia University of Queensland Princess Alexandra HospitalBrisbaneQLD 4000Australia Macquarie University Hospital SydneyNSW 2109Australia

The artificial urinary sphincter(AUS)remains the standard of care in men with severe stress urinary incontinence(SUI)following prostate surgery and *** the current AUS provides an effective,safe,and durable treatment option,it is not without its limitations and complications,especially with regard to its utility in some“high-risk”*** article provides a critical review of relevant publications pertaining to AUS surgery in specific high-risk groups such as men with spinal cord injury,revision cases,concurrent penile prosthesis implant,and female *** discussion of each category includes a brief review of surgical challenge and a practical action-based set of *** increased understandings of the pathophysiology of various SUI cases coupled with effective therapeutic strategies to enhance AUS surgery continue to improve clinical outcomes of many patients with SUI.

关键词： artificial urinary sphincter female stress incontinence penile prosthesis implant revision surgery spinal cord injury urinary incontinence

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Penile prosthesis implant in the special populations:diabetics,neurogenic conditions,fibrotic cases,concurrent urinary continence surgery,and salvage implants

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Asian Journal of Andrology 2020年第1期22卷 39-44页

作者： eric Chung AndroUrology Centre BrisbaneQLD 4000Australia University of Queensland Princess Alexandra HospitalBrisbaneQLD 4000Australia Macquarie University Hospital SydneyNSW 2109Australia

Penile prosthesis implant(PPI)remains an effective and safe treatment option for men with erectile dysfunction(ED).However,PPI surgery can be associated with a higher risk of complications in certain *** article provides a critical review of relevant publications pertaining to PPI in men with diabetes,significant corporal fibrosis,spinal cord injury,concurrent continence surgery,and complex salvage *** discussion of each category of special populations includes a brief review of the surgical challenges and a practical action-based set of *** specific patient populations posed considerable challenges in PPI surgery,strict pre-and postoperative management coupled with safe surgical practice is a prerequisite to achieving excellent clinical outcomes and high patient satisfaction rate.

关键词： continence surgery diabetes erectile dysfunction penile prosthesis implant Peyronie’s disease priapism salvage surgery spinal cord injury

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Photocatalytic degradation of dye effluent by titanium dioxide pillar pellets in aqueous solution

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Journal of Environmental Sciences 2004年第3期16卷 375-379页

作者： eric Hu School of Engineering and Technology

Photocatalytic oxidation(PCO) process is an effective way to deal with organic pollutants in wastewater which could be difficult to be degraded by conventional biological treatment methods. Normally the TiO 2 powder in nanometre size range was directly used as photocatalyst for dye degradation in wastewater. However the titanium dioxide powder was arduous to be recovered from the solution after treatment. In this application, a new form of TiO 2(i. e. pillar pellets ranging from 2 5 to 5 3 mm long and with a diameter of 3 7 mm) was used and investigated for photocatalytic degradation of textile dye effluent. A test system was built with a flat plate reactor(FPR) and Uv light source(blacklight and solar simulator as light source respectively) for investigating the effectiveness of the new form of TiO 2. It was found that the photocatalytic process under this configuration could efficiently remove colours from textile dyeing effluent. Comparing with the TiO 2 powder, the pellet was very easy to recovered from the treated solution and can be reused in multiple times without the significant change on the photocatalytic property. The results also showed that to achieve the same photocatalytic performance, the FPR area by pellets was about 91% smaller than required by TiO 2 powder. At least TiO 2 pellet could be used as an alternative form of photocatalyst in applications for textile effluent treatment process, also other wastewater treatment processes.

关键词： dyes degradation photocatalytic reactions TiO 2 catalyst

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Waveform LiDAR concepts and applications for potential vegetation phenology monitoring and modeling:a comprehensive review

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Geo-Spatial Information Science 2021年第2期24卷 179-200,I0001页

作者： eric Ariel L Salas Agricultural Research Development Program(ARDP) Central State UniversityWilberforceUSA

Researchers continually demonstrated through published literature how LiDAR could create unparalleled measurements of ecosystem structure and forest *** are a number of studies conducted utilizing waveform LiDAR products for terrestrial monitoring,but those that deal specifically with the assessment of space-borne waveform LiDAR for monitoring and modeling of phenology is very *** review highlights the waveform LiDAR system and looks into satellite sensors that could link waveform LiDAR and vegetation phenology,such as the proposed NASA’s Global Ecosystem Dynamics Investigation(GEDI)and the Japanese Experimental Module(JEM)-borne LiDAR sensor named MOLI(Multi-footprint Observation LIDAR and Imager).Further,this work examines the richness and utility of the waveform returns and proposes a spline-function-derived model that could be exploited for estimating the leaf-shooting *** new approach may be utilized for ecosystem-level phenological studies.

关键词： Ecosystems gedi moli phenology vegetation modeling waveform LiDAR

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