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Advances in the treatment of autism spectrum disorder:Wharton jelly mesenchymal stem cell transplantation

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World Journal of Methodology 2025年第1期15卷 72-79页

作者： Serdar Kabatas ErdinçCivelek Eyüp Can Savrunlu Umut Karaaslan Özlem Yıldız erdal Karaöz Department of Neurosurgery University of Health Sciences TurkeyGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Pediatric Allergy-Immunology Institute of Health Sciences Marmara UniversityIstanbul 34865Türkiye Center for Stem Cell&Gene Therapy Research and Practice University of Health Sciences TurkeyIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry University of Health SciencesGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry Kocaeli University Faculty of MedicineKocaeli 41001Türkiye Center for Regenerative Medicine and Stem Cell Research&Manufacturing Liv HospitalIstanbul 34340Türkiye Department of Histology and Embryology Istinye UniversityFaculty of MedicineIstanbul 34010Türkiye Center for Stem Cell and Tissue Engineering Research and Practice Istinye UniversityIstanbul 34340Türkiye

BACKGROUND Autism spectrum disorder(ASD)is a complex neurodevelopmental disorder with multifaceted *** recent studies,neuroinflammation and immune dysregulation have come to the forefront in its *** are studies suggesting that stem cell therapy may be effective in the treatment of *** To evolve the landscape of ASD treatment,focusing on the potential benefits and safety of stem cell *** A detailed case report is presented,displaying the positive outcomes observed in a child who underwent intrathecal and intravenous Wharton’s jelly-derived mesenchymal stem cells(WJ-MSCs)transplantation combined with *** The study demonstrates a significant improvement in the child’s functional outcomes(Childhood Autism Rating Scale,Denver 2 Developmental Screening Test),especially in language and gross motor *** serious side effects were encountered during the 2-year *** The findings support the safety and effectiveness of WJ-MSC transplantation in managing ASD.

关键词： Autism spectrum disorder Neurorehabilitation Stem cell transplantation Wharton jelly mesenchymal stem cells Inflammation

Effect of 0h11/2 Level on Shell Model Calculations of ^105Sb and ^107Sb

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Chinese Physics Letters 2006年第6期23卷 1430-1433页

作者： erdal Dikmen Department of Physics Siileyman Demirel University Isparta Turkey

The full and reduced shell model calculations have been carried out for the light odd-even ^105Sb and ^107Sb isotopes. The model space has been chosen as 1d5/2, 0g7/2, 1d3/2, 2s1/2, and 0h11/2 for the full calculations and excluded 0h11/2 for the reduced calculations. The reduced shell model calculations of ^105Sb and ^107Sb isotopes are presented for the first time. We obtain the energy spectra for the ^105Sb and ^107Sb isotopes in the full and reduced model space by using CD-Bonn two-body effective nucleon-nucleon interaction. The resulting energy spectra are compared to the experimental results to understand the effect of the 0h11/2 level on the shell model calculations. We draw conclusions about the right model space in the shell model calculations for the isotopes around the N =Z= 50 region of the periodic table.

关键词： Shell Model Calculations periodic table

A New Hybrid Approach Using GWO and MFO Algorithms to Detect Network Attack

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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1277-1314页

作者： Hasan Dalmaz erdal erdal Halil Muratünver Department of Computer Engineering Faculty of Engineering and ArchitectureKırıkkale UniversityKırıkkale71450Turkey

This paper addresses the urgent need to detect network security attacks,which have increased significantly in recent years,with high accuracy and avoid the adverse effects of these *** intrusion detection system should respond seamlessly to attack patterns and *** use of metaheuristic algorithms in attack detection can produce near-optimal solutions with low computational *** achieve better performance of these algorithms and further improve the results,hybridization of algorithms can be used,which leads to more successful ***,many studies are conducted on this *** this study,a new hybrid approach using Gray Wolf Optimizer(GWO)and Moth-Flame Optimization(MFO)algorithms was developed and applied to widely used data sets such as NSL-KDD,UNSW-NB15,and CIC IDS 2017,as well as various benchmark *** ease of hybridization of the GWO algorithm,its simplicity,its ability to perform global optimal search,and the success of the MFO algorithm in obtaining the best solution suggested that an effective solution would be obtained by combining these two *** these reasons,the developed hybrid algorithm aims to achieve better results by using the good aspects of both the GWO algorithm and the MFO *** reviewing the results,it was found that a high level of success was achieved in the benchmark *** achieved better results in 12 of the 13 benchmark functions *** addition,the success rates obtained according to the evaluation criteria in the different data sets are also *** the 97.4%,98.3%,and 99.2% classification accuracy results obtained in the NSL-KDD,UNSW-NB15,and CIC IDS 2017 data sets with the studies in the literature,they seem to be quite successful.

关键词： Network attack detection hybrid GWO MFO

Shell Model Description of Neutron-Deficient Sn Isotopes

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Communications in Theoretical Physics 2009年第5期51卷 899-903页

作者： erdal Dikmen Department

The shell model calculations in the sdgh major shell for the neutron-deficient ^106,107,108,109Sn isotopes have been carried out by using CD-Bonn and Nijmegenl two-body effective nucleon-nucleon interactions. The singleshell states and the corresponding matrix elements needed for describing Sn isotopes are reconstructed to calculate the coefficient of fractional parantage by reducing the calculation requirements. This reconstruction allows us to do the shell model calculations of the neutron deficient Sn isotopes in very reasonable time. The results are compared to the recent high-resolution experimental data and found to be in good agreement with experiments.

关键词： shell model low-lying states effective interactions

A fixed point theorem for Proinov mappings with a contractive iterate

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Applied Mathematics(A Journal of Chinese Universities) 2023年第3期38卷 403-412页

作者： erdal Karapnar Andreea Fulga Department of Medical Research China Medical UniversityTaichungTaiwanChina Department of Mathematics Cankaya University06790EtimesgutAnkaraTurkey Department of Mathematics and Computer Science Transilvania University of BrasovBrasovRo-mania.

In this paper,we consider the fixed point theorem for Proinov mappings with a contractive iterate at a *** other words,we combine and unify the basic approaches of Proinov and Sehgal in the framework of the complete m... 详细信息

关键词： contractive iterate at a point Proinov mappings fixed point theorems

Relations between Simplicial Groups, 3-Crossed Modules and 2-Quadratic Modules

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Acta Mathematica Sinica,English Series 2014年第6期30卷 968-984页

作者： Hasan ATK erdal ULUALAN Department of Mathematics stanbul Medeniyet University Department of Mathematics Dumlup?nar University

In this paper, we define two-quadratic module and explore the relations among two-quadratic modules, three-crossed modules and simplicial groups.

关键词： Simplicial group quadratic module grossed module

MEIR-KEELER TYPE CONTRACTIONS FOR TRIPLED FIXED POINTS

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Acta Mathematica Scientia 2012年第6期32卷 2119-2130页

作者： Hassen Aydi erdal Karapvnar Calogero Vetro Universitde Monastir Institut Supérieur d'Informatique de MahdiaRoute de RéjicheKm 4BP 35Mahdia 5121Tunisie Department of Mathematics Atilim University 06836IncekAnkaraTurkey Dipartimento di Matematica e Informatica Universitàdi PalermoVia Archirafi3490123 PalermoItaly

In 2011, Berinde and Borcut [6] introduced the notion of tripled fixed point in partially ordered metric spaces. In our paper, we give some new tripled fixed point theorems by using a generalization of Meir-Keeler con... 详细信息

关键词： tripled fixed point theorems Meir-Keeler type contractions partially or-dered sets

Influences of Pr and Ta doping concentration on the characteristic features of FTO thin film deposited by spray pyrolysis

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Chinese Physics B 2015年第10期24卷 414-422页

作者： Güven Turgut Adem Koqyigit erdal Snmez Erzurum Technical University Science FacultyDepartment of Basic Sciences Igdir University Engineering FacultyDepartment of Electrical Electronic Engineering Ataturk University Kazim Karabekir Education FacultyDepartment of Physics

The Pr and Ta separately doped FTO（10 at.% F incorporated Sn O2） films are fabricated via spray pyrolysis. The microstructural, topographic, optical, and electrical features of fluorine-doped TO（FTO） films are investigated as functions of Pr and Ta dopant concentrations. The x-ray diffraction（XRD） measurements reveal that all deposited films show polycrystalline tin oxide crystal property. FTO film has（200） preferential orientation, but this orientation changes to（211） direction with Pr and Ta doping ratio increasing. Atomic force microscopy（AFM） and scanning electron microscopy（SEM） analyses show that all films have uniform and homogenous nanoparticle distributions. Furthermore, morphologies of the films depend on the ratio between Pr and Ta dopants. From ultraviolet-visible（UV-Vis） spectrophotometer measurements, it is shown that the transmittance value of FTO film decreases with Pr and Ta doping elements increasing. The band gap value of FTO film increases only at 1 at.% Ta doping level, it drops off with Pr and Ta doping ratio increasing at other doped FTO films. The electrical measurements indicate that the sheet resistance value of FTO film initially decreases with Pr and Ta doping ratio decreasing and then it increases with Pr and Ta doping ratio increasing. The highest value of figure of merit is obtained for 1 at.% Ta- and Pr-doped FTO film. These results suggest that Pr- and Ta-doped FTO films may be appealing candidates for TCO applications.

关键词： Pr-doped FTO Ta-doped FTO spray pyrolysis tin oxide thin films double doping

Fitting Single Particle Energies in sdgh Major Shell

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Communications in Theoretical Physics 2015年第2期63卷 222-228页

作者： erdal Dikmen Oguz ztrk Yavuz Cengiz Department of Physics Sleyman Demirel University Department of Electronics and Communication Engineering Sleyman Demirel University

We have performed two kinds of non-linear fitting procedures to the single-particle energies in the sdgh major shell to obtain better shell model results. The low-lying energy eigenvaiues of the light Sn isotopes with A = 103 - 110 in the sdgh-shell are calculated in the framework of the nuclear shell model by using CD-Bonn two-body effective nucleon- nucleon interaction. The obtained energy eigenvalues are fitted to the corresponding experimental values by using two different non-linear fitting procedures, i.e., downhill simplex method and clonai selection method. The unknown single-particle energies of the states 2s1/2, ld3/2, and Oh11/2 are used in the fitting methods to obtain better spectra of the 104,106,108,110Sn isotopes, We compare the energy spectra of the 104,106,108,110Sn and 103,105,107,109Sn isotopes with/without a nonlinear fit to the experimental results.

关键词： shell model optimization of single-particle energies Sn isotopes