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Assessing the impact of concurrent high-fructose and highsaturated fat diets on pediatric metabolic syndrome:A review

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World Journal of Clinical Pediatrics 2024年第2期13卷 62-79页

作者： Manuel Alejandro Vargas-Vargas marcela González-Montoya Olin Torres-Isidro Claudia Isabel García-Berumen Omar Ortiz-Avila Elizabeth calder.n-Cortés Christian Cortés-Rojo Instituto de Investigaciones Químico–Biológicas Universidad Michoacana de San Nicolás de HidalgoMorelia 58030MichoacánMexico Facultad de Enfermería Universidad Michoacana de San Nicolás de HidalgoMorelia 58020MichoacánMexico

High-saturated fat(HF)or high-fructose(HFr)consumption in children predispose them to metabolic syndrome(MetS).In rodent models of MetS,diets containing individually HF or HFr lead to a variable degree of ***,simultaneous intake of HF plus HFr have synergistic effects,worsening MetS *** children,the effects of HF or HFr intake usually have been addressed ***,we have reviewed the outcomes of HF or HFr diets in children,and we compare them with the effects reported in *** humans,HFr intake causes increased lipogenesis,hypertriglyceridemia,obesity and insulin *** the other hand,HF diets promote low grade-inflammation,obesity,insulin *** the deleterious effects of simultaneous HF plus HFr intake on MetS development in rodents,there is little information about the combined effects of HF plus HFr intake in *** aim of this review is to warn about this issue,as individually addressing the effects produced by HF or HFr may underestimate the severity of the outcomes of Western diet intake in the pediatric *** consider that this is an alarming issue that needs to be assessed,as the simultaneous intake of HF plus HFr is common on fast food menus.

关键词： Fructose Saturated fat Metabolic syndrome Insulin resistance Type 2 diabetes Ultra processed foods Children Obesity Dyslipidemia non-alcoholic fatty liver disease

Airborne bacteria associated with particulate matter from a highly urbanised metropolis:A potential risk to the population’s health

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Frontiers of Environmental Science & Engineering 2022年第9期16卷 99-114页

作者： maría del Carmen calder.n-Ezquerro Elizabeth Selene Gómez-Acata Carolina Brunner-Mendoza Instituto de Ciencias de la Atmósfera y Cambio Climático Universidad Nacional Autónoma de MéxicoCiudad de México 04510Mexico Facultad de Medicina Universidad Nacional Autónoma de MéxicoCiudad de México 04510Mexico

Bacteria in the air present patterns in space and time produced by different sources and environmental *** studies have focused on the link between airborne pathogenic bacteria in densely populated cities,and the risk to the population’s *** associated with particulate matter(PM)were monitored from the air of Mexico City(Mexico).We employed a metagenomic approach to characterise bacteria using the 16S rRnA *** bacteria sampling was carried out in the north,centre,and south of Mexico City,with different urbanisation rates,during *** added to the particles were sampled using high-volume PM_(10) *** ascertain significant differences in bacterial diversity between zones and seasons,the Kruskal-Wallis,Wilcoxon tests were done on alpha diversity ***-three air samples were collected,and DnA was sequenced using next-generation *** results indicated that the bacterial phyla in the north and south of the city were Firmicutes,Cyanobacteria,Proteobacteria,and Actinobacteria,while in the central zone there were more *** were no differences in the alpha diversity indices between the sampled *** to the OTUs,the richness of bacteria was higher in the central *** diversity was higher in the rainy season than in the dry season;the Shannon index and the OTUs observed were higher in the central zone in the dry *** bacteria such as Kocuria,Paracoccus,and Micrococcus predominated in both seasonal times,while Staphylococcus,Corynebacterium,and nocardioides were found during the rainy season,with a presence in the central zone.

关键词： Airborne bacteria Urbanisation PM10 Mexico City Microbiome

Caerulin-induced pancreatitis in rats: Histological and genetic expression changes from acute phase to recuperation

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World Journal of Gastroenterology 2006年第25期12卷 3999-4003页

作者： Javier Magaa-Gómez Guillermo López-Cervantes Ana maría calder.n de la Barca Departamento de nutrición Centro de Investigación en Alimentación y Desarrollo A.C. HermosilloSonoraMéxicoDepartamento de Patología Hospital Infantil del Estado de SonoraHermosilloSonoraMéxicoDepartamento de Nutrición Centro de Investigación en Alimentación y DesarrolloA.C.HermosilloSonoraMéxico

瞄准：为了学习组织学、联系胰腺炎的蛋白质 mRnA 累积，在老鼠从导致 caerulin 的胰腺炎的尖锐阶段胰改变到恢复。方法：尖锐胰腺炎被 caerulein 在男 Wistar 老鼠导致并且列在后面在上面为 90 d 由组织学并且胰的 mRnA 分析。胰在 0 ... 详细信息

瞄准：为了学习组织学、联系胰腺炎的蛋白质 mRnA 累积，在老鼠从导致 caerulin 的胰腺炎的尖锐阶段胰改变到恢复。方法：尖锐胰腺炎被 caerulein 在男 Wistar 老鼠导致并且列在后面在上面为 90 d 由组织学并且胰的 mRnA 分析。胰在 0 点被把， 9， 24 h 并且 3， 5， 15， 30， 60， 90 d 正式就职以后。浮肿(E) ， polymorphonuclear neutrophil (PMn ) 渗入，细胞质的空泡形成(V) ，酶原小粒弄空(ZD ) 和腺泡组织的破坏(广告) 是评估的用显微镜。联系胰腺炎的蛋白质(奶头) 和 L13A mRnAs 的累积被即时 PCR 确定。结果：主要组织学的变化出现在为 PMn 渗入和细胞质的 V 正式就职以后的 9 h 在为 E 和 ZD 的 24 h 和 3 d 分别地。所有参数在 5 d 以后被恢复，除了推迟了超过 30 d 的 ZD。主要广告在 15 d 以后被观察，值在 30 d 以后回到了正常。同样到组织学的变化， PAP mRnA 的累积在 24 h 与最高的累积在 9 h 被增加，差别消失在 5 d 以后。结论：从尖锐阶段发生到胰的胰腺炎，新生和重新区别的恢复并且奶头表示是只胰腺炎的尖锐回答。

关键词：雨蛙肽胰腺炎组织遗传疾病

Operational definitions and measurement of externalizing behavior problems:An integrative review including research models and clinical diagnostic systems

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World Journal of Psychiatry 2023年第6期13卷 278-297页

作者： Lidia Torres-Rosado Oscar M Lozano Manuel Sanchez-Garcia Fermín Fernández-calder.n Carmen Diaz-Batanero Department of Clinical and Experimental Psychology University of HuelvaHuelva 21071Spain Research Center for natural Resources Health and EnvironmentUniversity of HuelvaHuelva 21071Spain

Measurement of externalizing disorders such as antisocial disorders,attentiondeficit/hyperactivity disorder or borderline disorder have relevant implications for the daily lives of people with these *** the Diagnostic and Statistical Manual of Mental Disorders(DSM)and the International Classification of Diseases(ICD)have provided the diagnostic framework for decades,recent dimensional frameworks question the categorical approach of psychopathology,inherent in traditional *** and instruments develop under the DSM or ICD framework preferentially adopt this categorical approach,providing diagnostic *** contrast,dimensional measurement instruments provide an individualized profile for the domains that comprise the externalizing spectrum,but are less widely used in *** paper aims to review the operational definitions of externalizing disorders defined under these different frameworks,revise the different measurement alternatives existing,and provide an integrative operational ***,an analysis of the operational definition of externalizing disorders among the DSM/ICD diagnostic systems and the recent Hierarchical Taxonomy of Psychopathology(HiTOP)model is carried ***,in order to analyze the coverage of operational definitions found,a description of measurement instruments among each conceptualization is *** phases in the development of the ICD and DSM diagnosis systems can be observed with direct implications for *** and DSM versions have progressively introduced systematicity,providing more detailed descriptions of diagnostic criteria and categories that ease the measurement instrument ***,it is questioned whether the DSM/ICD systems adequately modelize externalizing disorders,and therefore their *** recent theoretical approaches,such as the HiTOP model seek to overcome some of the criticism raised towards the classification ***,several issues

关键词： Externalizing disorders Measurement Diagnostic and Statistical Manual of Mental Disorders International Classification of Diseases Hierarchical Taxonomy of Psychopathology Psychopathology

On Integrable Roots in Split Lie Triple Systems

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Acta Mathematica Sinica,English Series 2009年第11期25卷 1759-1774页

作者： A.J.calder.n marTín Departamento de Matemáticas Universidad de Cádiz

We focus on the notion of an integrable root in the framework of split Lie triple systems T with a coherent 0-root space. As a main result, it is shown that if T has all its nonzero roots integrable, then its standard embedding is a split Lie algebra having all its nonzero roots integrable. As a consequence, a local finiteness theorem for split Lie triple systems, saying that whenever all nonzero roots of T are integrable then T is locally finite, is stated. Finally, a classification theorem for split simple Lie triple systems having all its nonzero roots integrable is given.

关键词： Lie triple system root split Lie algebra classification theory

What can we learn from β-cell failure biomarker application in diabetes in childhood?A systematic review

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World Journal of Diabetes 2021年第8期12卷 1325-1362页

作者： maría F calder.n-Hernández nelly F Altamirano-Bustamante Cristina Revilla-Monsalve maría Belen Mosquera-Andrade Myriam M Altamirano-Bustamante Unidad de Investigación en Enfermedades Metabólicas Centro Médico Nacional Siglo XXIIMSSMexico 06720Mexico Department of Endocrinology Instituto Nacional de PediatríaMexico 04530Mexico

BACKGROUnD The prevalence of diabetes as a catastrophic disease in childhood is growing in the *** search for novel biomarkers ofβ-cell failure has been an elusive task because it requires several clinical and biochemical measurements in order to integrate the risk of metabolic *** To determine which biomarkers are currently used to identifyβ-cell failure among children and adolescents with high risk factors for diabetes *** This systematic review was carried out using a modified version of the PICO protocol(Participants/Intervention/Comparison/Outcome).Once our research question was established,terms were individually researched on three different databases(PubMed,BIREME and Web of Science).The total articles obtained underwent a selection process from which the 78 most relevant articles were retrieved to undergo further *** were assessed individually according to quality *** First,we made the classification of theβ-cell-failure biomarkers by the target tissue and the evolution of the disease,separating the biomarkers in relation to the types of ***,we demonstrated that most biomarkers currently used as early signs ofβ-cell failure are those that concern local or systemic inflammation processes and oxidative stress as well as those related to endothelial dysfunction ***,we explored the novelties of diabetes as a protein conformational disease and the novel biomarker called real human islet amyloid polypeptide amyloid ***,we ended with a discussion about the best practice of validation and individual control of using different types of biomarkers in type 1 and type 2 diabetes in order to assess the role they play in the progress of diabetes in *** This review makes widely evident that most biomarkers currently used as early signs ofβ-cell failure are those that concern local or systemic inflammation processes and oxidative stress as well as those related to endo

关键词： Biomarker β-cell failure Children Adolescents Diabetes mellitus Metabolic syndrome

Insulin resistance is associated with subclinical vascular disease in humans

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World Journal of Diabetes 2019年第2期10卷 63-77页

作者： maría M Adeva-Andany Eva Ameneiros-Rodríguez Carlos Fernández-Fernández Alberto Domínguez-Montero Raquel Funcasta-calder.n Internal Medicine Department Hospital General Juan Cardona

Insulin resistance is associated with subclinical vascular disease that is not justified by conventional cardiovascular risk factors,such as smoking or *** injury associated to insulin resistance involves functional and structural damage to the arterial wall that includes impaired vasodilation in response to chemical mediators,reduced distensibility of the arterial wall(arterial stiffness),vascular calcification,and increased thickness of the arterial *** dysfunction associated to insulin resistance is present in asymptomatic subjects and predisposes to cardiovascular diseases,such as heart failure,ischemic heart disease,stroke,and peripheral vascular *** and functional vascular disease associated to insulin resistance is highly predictive of cardiovascular morbidity and *** pathogenic mechanisms remain *** studies have demonstrated that animal protein consumption increases the risk of developing cardiovascular disease and predisposes to type 2 diabetes(T2D)whereas vegetable protein intake has the opposite *** disease linked to insulin resistance begins to occur early in *** and adolescents with insulin resistance show an injured arterial system compared with youth free of insulin resistance,suggesting that insulin resistance plays a crucial role in the development of initial vascular *** of the vascular dysfunction related to insulin resistance should begin early in *** the clinical onset of T2D,asymptomatic subjects endure a long period of time characterized by insulin *** vascular dysfunction begins to develop during this phase,so that patients with T2D are at increased cardiovascular risk long before the diagnosis of the disease.

关键词： Diabetes Cardiovascular risk Arterial stiffness Arterial elasticity Intimamedia thickness Vascular calcification Insulin resistance Animal protein Vegetable protein WJD

A Crystallization Study of nanocrystalline PZT 53/47 Granular Arrays Using a Sol-Gel Based Precursor

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Journal of Materials Science & Technology 2011年第6期27卷 489-496页

作者： A.Surez-Gómez J.M.Saniger-Blesa F.calder.n-Pinar CCADET-Universidad nacional Autónoma de México Cd.UniversitariaCirc.Exterior s/nA.P.70-186Coyoacn 04510México D.F.México Laboratorio de Ingeniería Electroquímica Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoCd.UniversitariaCoyoacn 04510México D.F.México Facultad de Física/IMRE San Lzaro y LUniversidad de la Habana

In this work,we intend to perform a detailed study on the crystallization process of PZT 53/47 nanostructured powders by starting out with an amorphous precursor synthesized by a sol-gel based *** interests also lie in the feasibility for controlling the average grain size of the final structure in the submicron range on an ab initio ***,Fourier transform infrared spectroscopy（FT-IR）,Raman（Stokes and Anti-Stokes）,X-ray diffraction（XRD） and scanning electron microscopy（SEM） are used to examine the microstructural characteristics based on previously reported differential thermal analysis/thermal gravimetric analysis（DTA/TGA） *** results show a crystallization temperature of 800℃ to attain pure perovskite phase with excellent morphological quality,average grain size 〈DG〉〈 300 nm and with average crystallite size 〈DC〉〈15 nm.

关键词： Powders-chemical preparation PZT synthesis Sol-gel precursors Microstructure- final Vibrational spectroscopies X-ray diffraction

THE BAnACH-LIE GROUP OF LIE TRIPLE AUTOMORPHISMS OF An H^＊-ALGEBRA^＊

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Acta Mathematica Scientia 2010年第4期30卷 1219-1226页

作者： A.J.calder.n martín C.martín González Departamento de Matemáticas Universidad de Cádiz Departamento de Algebra Geometría y Topología Universidad de Málaga

We study the Banach-Lie group Ltaut（A） of Lie triple automorphisms of a complex associative H^＊-algebra A. Some consequences about its Lie algebra, the algebra of Lie triple derivations of A, Ltder（A）, are obtained. For a topologically simple A, in the infinite-dimensional case we have Ltaut（A）0 = Aut（A） implying Ltder（A） = Der（A）. In the finite-dimensional case Ltaut（A）0 is a direct product of Aut（A） and a certain subgroup of Lie derivations δ from A to its center, annihilating commutators.

关键词： Banach-Lie group Lie triple automorphism Lie triple derivation