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The level and influencing factors of gerotranscendence in community-dwelling older adults

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International Journal of Nursing Sciences 2015年第2期2卷 123-127页

作者： Ke Wang Gong-xiang Duan Hong-li Jia er-shan xu xue-mei Chen Hong-hui Xie School of Nursing University of South ChinaHengyangHunan ProvincePeople's Republic of China Community of Qingshan HengyangHunan ProvincePeople's Republic of China

Purpose:To study the level and influencing factors of gerotranscendence in communitydwelling older ***:We investigated 772 community-dwelling older adults in Hengyang in the Hunan Province of the People's Republic of China using a translated Gerotranscendence Scale and demographic ***:The community-dwelling older adults had an overall intermediate level of ***-way analysis of variance and multiple linear regression analysis showed that sex,living arrangements,regular activities,and religious affiliation influenced the gerotranscendence perspective of the community-dwelling older adults(perotranscendence perspective were not significantly *** covariates clarified about 38.8%of the variation in gerotranscendence ***:Our findings suggest that sex,regular activities,religious affiliation,and living arrangement influence *** findings can guide the planning and implementation of better practices in elderly care by nurses and other healthcare professionals.

关键词： Community-dwelling older adults Gerotranscendence Influencing factors

Nanomedicine targeting ferroptosis to overcome anticancer therapeutic resistance

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Science China(Life Sciences) 2024年第1期67卷 19-40页

作者： Jing Cai Xiaoding xu Phei er Saw Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineMedical Research CenterSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Nanhai Translational Innovation Center of Precision Immunology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityFoshan 528200China

A potential reason for the failure of tumor therapies is treatment *** to chemotherapy,radiotherapy,and immunotherapy continues to be a major obstacle in clinic,resulting in tumor recurrence and *** major mechanisms of therapy resistance are inhibitions of cell deaths,like apoptosis and necrosis,through drug inactivation and excretion,repair of DNA damage,tumor heterogeneity,or changes in tumor microenvironment,*** studies have shown that ferroptosis play a major role in therapies resistance by inducing phospholipid peroxidation and iron-dependent cell *** ferroptosis inducers in combination with clinical treatment techniques have been used to enhance the effect in tumor ***,versatile ferroptosis nanoinducers exhibit an extensive range of functions in reversing therapy resistance,including directly triggering ferroptosis and feedback ***,we provide a detailed description of the design,mechanism,and therapeutic application of ferroptosis-mediated synergistic tumor *** also discuss the prospect and challenge of nanomedicine in tumor therapy resistance by regulating ferroptosis and combination therapy.

关键词： ferroptosis cancer therapy therapy resistance nanoinducers

Consolidation of high replacement ratio stone column-reinforced ground:Analytical solutions incorporating clogging effect

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 3311-3326页

作者： Jinxin Sun Mengmeng Lu Baolong xu Jie shan School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou221116China Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou221006China

The utilization of stone columns has emerged as a popular ground improvement strategy,whereas the drainage performance can be adversely hampered by clogging *** the ample progress of calculation methods for the consolidation of stone column-improved ground,theoretical investigations into the clogging effect have not been thoroughly ***,it is imperative to involve the column consolidation deformation to mitigate computational error on the consolidation of composite ground with high replacement *** this context,an analytical model accounting for the initial clogging and coupled time and depth-dependent clogging of stone columns is ***,the resulting governing equations and analytical solutions are obtained under a new flow continuity relationship to incorporate column consolidation *** accuracy and reliability of the proposed model are illustrated by degradation analysis and case studies with good ***,the computed results of the current study are juxtaposed against the existing models,and an in-depth assessment of the impacts of several crucial parameters on the consolidation behavior is *** results reveal that ignoring column consolidation deformation leads to an overestimate of the consolidation rate,with maximum error reaching up to 16%as the replacement ratio ***,the initial clogging also has a significant influence on the consolidation ***,the increment of depth and time-clogging factors a and b will induce a noticeable retardation of the consolidation process,particularly in the later stage.

关键词： Consolidation Composite ground Stone column Clogging effect Ground improvement Analytical model

Recyclable hydrolyzed polymers of intrinsic microporosity-1/Fe_(3)O_(4) magnetic composites as adsorbents for selective cationic dye adsorption

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Frontiers of Chemical Science and Engineering 2024年第2期18卷 113-125页

作者： Feng Zhang Shuainan xu Xiumei Geng Meixia shan Yatao Zhang School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China

Polymers of intrinsic microporosity shows great potential for dye adsorption and magnetic Fe_(3)O_(4) are easy to be *** this work,hydrolyzed polymers of intrinsic microporosity-1/Fe_(3)O_(4) composite adsorbents were prepared by phase inversion and hydrolysis process for cationic dye *** chemical structure and morphology of the composite adsorbents were systematically characterized by several characterization *** methylene blue as the target dye,the influences of solution pH,contact time,initial dye concentration,and system temperature on the methylene blue adsorption process were *** incorporation of Fe_(3)O_(4) particle into hydrolyzed polymers of intrinsic microporosity-1 endow the adsorbent with high magnetic saturation(20.7 emu·g^(–1))which allows the rapid separation of the ***,the adsorption process was simulated by adsorption kinetics,isotherms and thermodynamics to gain insight onto the intrinsic adsorption *** addition,the composite adsorbents are able to selectively adsorb cationic dyes from mixed dyes *** polymers of intrinsic microporosity/Fe_(3)O_(4) shows only a slight decrease for methylene blue adsorption after 10 adsorption/regeneration cycles,demonstrating the outstanding regeneration *** high adsorption capacity,outstanding regeneration ability,together with simple preparation method,endow the composite adsorbents great potential for selective removal of cationic dyes in wastewater system.

关键词： polymers of intrinsic microporosity magnetic adsorbent cationic dye adsorption

Influence of Incomplete Soil Plugs on Bearing Capacities of Bucket Foundations in Clay

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China Ocean Engineering 2024年第1期38卷 144-155页

作者： LI Hui-shan LIU Run YANG xu LIAN Ji-jian State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation Tianjin UniversityTianjin 300072China School of Civil Engineering Tianjin UniversityTianjin 300072China Institute of Marine Energy and Intelligent Construction Tianjin University of TechnologyTianjin 300384China

Due to the uneven seabed and heaving of soil during pumping,incomplete soil plugs may occur during the installation of bucket foundations,and the impacts on the bearing capacities of bucket foundations need to be *** this paper,the contact ratio(the ratio of the top diameter of the soil plug to the diameter of the bucket)and the soil plug ratio(the ratio of the soil heave height to the skirt height)are defined to describe the shape and size of the incomplete soil ***,finite element models are established to investigate the bearing capacities of bucket foundations with incomplete soil plugs and the influences of the contact ratios,and the soil plug ratios on the bearing capacities are *** results show that the vertical bearing capacity of bucket foundations in homogeneous soil continuously improves with the increase of the contact ***,in normally consolidated soil,the vertical bearing capacity barely changes when the contact ratio is smaller than 0.75,while the bearing capacity suddenly increases when the contact ratio increases to 1 due to the change of failure *** contact ratio hardly affects the horizontal bearing capacity of bucket ***,the moment bearing capacity improves with the increase of the contact ratio for small aspect ratios,but hardly varies with increasing contact ratio for aspect ratios larger than ***,the reduction coefficient method is proposed based on this analysis to calculate the bearing capacities of bucket foundations considering the influence of incomplete soil *** comparison results show that the proposed reduction coefficient method can be used to evaluate the influences of incomplete soil plug on the bearing capacities of bucket foundations.

关键词： bucket foundation incomplete soil plug uniaxial bearing capacity contact ratio soil plug ratio

Spherical Confinement Generates Entropic Force to Accelerate Polymer Chain Detachment

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Chinese Journal of Polymer Science 2024年第3期42卷 407-416,I0010页

作者： Yu-shan Zheng Jian-Ping Zhou Yan xu Kai Li Mechanical Engineering Xinjiang UniversityUrumqi 830002China

To understand the dynamic process of polymer detachment, it is necessary to determine the mean detachment time of a single breakable link, which is modeled as a spring. Normally, this time can be viewed as the escape of a Brownian particle from the potential well of the spring. However, as the free dangling length of the polymer chain increases, the conformational entropy of the chain is affected by geometric confinement. It means that the wall exerts a repulsive force on the chain, resulting in accelerated link detachment from a macroscopic perspective. In this work, we investigate the effect of entropy on the detachment rate in the case where the substrate is spherical. We demonstrate that spherical confinement accelerates chain detachment both inside and outside the sphere. An analytical expression for the mean detachment time of breakable links is given, which includes an additional pre-factor that is related to the partition function. Additionally, we analyze the expressions for entropic forces inside the sphere, outside the sphere, and on a flat wall, comparing their magnitudes to explain the difference in mean detachment time.

关键词： Polymer detachment Breakable link Entropic force Mean first passage time

HCRVD: A Vulnerability Detection System Based on CST-PDG Hierarchical Code Representation Learning

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Computers, Materials & Continua 2024年第6期79卷 4573-4601页

作者： Zhihui Song Jinchen xu Kewei Li Zheng shan School of Cyberspace Security Information Engineering UniversityZhengzhou450001China

Prior studies have demonstrated that deep learning-based approaches can enhance the performance of source code vulnerability detection by training neural networks to learn vulnerability patterns in code ***,due to limitations in code representation and neural network design,the validity and practicality of the model still need to be ***,due to differences in programming languages,most methods lack cross-language detection *** address these issues,in this paper,we analyze the shortcomings of previous code representations and neural *** propose a novel hierarchical code representation that combines Concrete Syntax Trees(CST)with Program Dependence Graphs(PDG).Furthermore,we introduce a Tree-Graph-Gated-Attention(TGGA)network based on gated recurrent units and attention mechanisms to build a Hierarchical Code Representation learning-based Vulnerability Detection(HCRVD)*** system enables cross-language vulnerability detection at the *** experiments show that HCRVD surpasses many competitors in vulnerability detection *** benefits from the hierarchical code representation learning method,and outperforms baseline in cross-language vulnerability detection by 9.772%and 11.819%in the C/C++and Java datasets,***,HCRVD has certain ability to detect vulnerabilities in unknown programming languages and is useful in real open-source *** shows good validity,generality and practicality.

关键词： Vulnerability detection deep learning CST-PDG code representation tree-graph-gated-attention network cross-language

Strong hetero-interface interaction in 2D/2D WSe2/ZnIn2S4 heterostructures for highly-efficient photocatalytic hydrogen generation

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Journal of Energy Chemistry 2024年第10期97卷 379-387页

作者： xu Guo Xing Liu Jing shan Zhuo xu Zhiming Fang Lu Wang Shengzhong Liu School of Energy Power and Mechanical Engineering North China Electric Power University Shaanxi Key Laboratory for Advanced Energy Devices School of Materials Science and Engineering Shaanxi Normal University Qinghai Advanced Energy Storage Laboratory SPIC Qinghai Photovoltaic Industry Innovation Center Co. Ltd.State Power Investment Corporation Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Green hydrogen is urgently required for sustainable development of human beings and rational construction of heterostructures holds great promising for photocatalytic hydrogen ***,2D/2D WSe2/ZnIn2S4heterostructures with strong hetero-interface interaction and abundant contact were constructed via an impregnation-annealing *** charge transfer from ZnIn2S4to WSe2was evidenced by transient absorption spectroscopy in crafted heterostructures owing to the tight and2D face-to-face *** a result,the prepared WSe2/ZnIn2S4heterostructures exhibited boosted photocatalytic performance and a highest hydrogen evolution rate of 3.377 mmol/（g h） was achieved with an apparent quantum yield of 45.7% at 420 *** work not only provides new strategies to achieve efficient 2D/2D heterostructures but also paves the way for the development of green hydrogen in the future.

关键词： Indium compounds

Reversal of complete atrioventricular block in dialysis patients following parathyroidectomy:A case report

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World Journal of Clinical Cases 2024年第7期12卷 1313-1319页

作者： shan-shan xu Li-Hai Hao Yan-Meng Guan Hemodialysis Center Weifang People’s HospitalWeifang 261041Shandong ProvinceChina

BACKGROUND Refractory secondary hyperparathyroidism(SHPT)is a common complication observed in patients with end-stage renal disease and can result in ectopic *** calcification involving the heart valves and the conduction system can easily lead to arrhythmias,including atrioventricular *** case report describes a maintenance hemodialysis patient with refractory SHPT resulting in a complete atrioventricular block(CAVB),which was eventually reversed to a first-degree atrioventricular *** SUMMARY We present the case of a 31-year-old Asian female who was receiving maintenance hemodialysis because of lupus *** developed SHPT,and an electrocardiogram revealed a first-degree atrioventricular ***,she underwent parathyroidectomy(PTX)with ***,a few years later,she developed SHPT again,and an electrocardiogram revealed a CAVB.A few years after the second PTX surgery,the calcification of the left atrium and left ventricle improved,and her CAVB was *** This case revealed that metastatic cardiac calcification can result in complete atrioventricular *** parathyroid surgery,calcification of the cardiac conduction system improved,leading to reversal of the atrioventricular *** is important for dialysis patients to optimize intact parathyroid hormone therapy and pay attention to calcification metastasis.

关键词： Secondary hyperparathyroidism Ectopic calcification Atrioventricular block Reversal Case report