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Application of indocyanine green-enhanced near-infrared fluorescence-guided imaging in laparoscopic lateral pelvic lymph node dissection for middle-low rectal cancer

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World Journal of Gastroenterology 2019年第31期25卷 4502-4511页

作者： Si-Cheng Zhou Yan-Tao Tian Xue-Wei Wang Chuan-Duo Zhao Shuai Ma Jun Jiang er-ni li Hai-Tao Zhou Qian liu Jian-Wei liang Zhi-Xiang Zhou Xi-Shan Wang Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Pancreatic and Gastric Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Radiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND As one effective treatment for lateral pelvic lymph node(LPLN)metastasis(LPNM),laparoscopic LPLN dissection(LPND)is limited due to the complicated anatomy of the pelvic sidewall and various complications after *** regard to improving the accuracy and completeness of LPND as well as safety,we tried an innovative method using indocyanine green(ICG)visualized with a near-infrared(niR)camera system to guide the detection of LPLNs in patients with middle-low rectal *** To investigate whether ICG-enhanced niR fluorescence-guided imaging is a better technique for LPND in patients with rectal *** A total of 42 middle-low rectal cancer patients with clinical LPNM who underwent total mesorectal excision(TME)and LPND between October 2017 and March 2019 at our institution were assessed and divided into an ICG group and a non-ICG *** characteristics,operative outcomes,pathological outcomes,and postoperative complication information were compared and analysed between the two *** Compared to the non-ICG group,the ICG group had significantly lower intraoperative blood loss(55.8±37.5 mL vs 108.0±52.7 mL,P=0.003)and a significantly larger number of LPLNs harvested(11.5±5.9 vs 7.1±4.8,P=0.017).The LPLNs of two patients in the non-IVG group were residual during *** addition,no significant difference was found in terms of LPND,LPNM,operative time,conversion to laparotomy,preoperative complication,or hospital stay(P>0.05).CONCLUSION ICG-enhanced niR fluorescence-guided imaging could be a feasible and convenient technique to guide LPND because it could bring specific advantages regarding the accuracy and completeness of surgery as well as safety.

关键词： Rectal cancer Lateral pelvic lymph node dissection Indocyanine green Lateral pelvic lymph node

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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu liang ni-Hui Zhang Zhi-Lai Zhan Guang-Lu Chang Yan Gao Xia li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

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Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong li li Dan Jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

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Dehydration at subduction zones and the geochemistry of slab fluids

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Science China Earth Sciences 2020年第12期63卷 1925-1937页

作者： Wancai li Huaiwei ni CAS Key Laboratory of Crust-Mantle Materials and Environments School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei230026China CAS Center for Excellence in Comparative Planetology Hefei230026China

Subducting oceanic slabs undergo metamorphic dehydration with the increase of temperature and pressure during *** is an essential step for element recycling,and slab fluids are critical agents for mediating slab-mantle *** is mainly controlled by the thermal structure of subduction zones and the stability of hydrous *** fore-arc depths,slab dehydration produces aqueous fluid with dissolved salts such as *** subduction proceeds deeper,the content of silicate components *** sub-arc and post-arc depths,a hydrous silicate melt is likely to form,or a supercritical fluid could arise from complete miscibility between silicates and H_(2)*** partitioning of elements between slab fluid and the residual solid rock is controlled by the type of fluid,and generally it is the supercritical fluid that is the most capable of mobilizing trace elements,being an effective carrier even for high field strength *** the chemistry of slab fluids relies on sophisticated integration of experiments,theoretical computation and investigation of natural rock *** contribution focuses on the content and speciation of key volatiles,including carbon,nitrogen and sulfur,in slab fluids as well as important fluid properties such as oxygen fugacity and *** properties of slab fluids show complicated variation under the control of mineral assemblages and T-P *** fluids at great depths of subductions have been inferred to be modestly alkaline and not necessarily very oxidizing as often *** progress in the research of slab dehydration and the chemistry and properties of slab fluids demands urgently the development of innovative experimental and computational technology including in situ analytical methods at high T-P.

关键词： Subduction zone Dehydration Slab fluids Volatiles Oxygen fugacity Acidity

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Ultraviolet humic-like component contributes to riverine dissolved organic matter biodegradation

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Journal of Environmental Sciences 2023年第2期124卷 165-175页

作者： Maofei ni Siyue li College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China Research Center for Environmental Ecology and Engineering School of Environmental Ecology and Biological EngineeringWuhan Institute of TechnologyWuhan 430205China The karst environmental geological hazard prevention laboratory of Guizhou Minzu University Guiyang 550025China Key Laboratory of Reservoir Aquatic Environment Research Center for EcohydrologyChongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China

Biological degradation of dissolved organic matter(DOM)regulates its structure and fate in river *** views suggested that labile components were dominantly consumed by microbial *** we provide new observations that a part of recalcitrant compounds largely contribute to riverine DOM *** excitationemission matrix fluorescent spectroscopy combined with peak picking and parallel factor analysis are used to explore component variability during DOM ***-like and tryptophan-like DOM are the primary components of riverine DOM,with proportion contributions of 39%–82% and 16%–61% for % of the maximumfluorescence intensity,*** 56 days of aerobic incubation in the dark,large amounts of tyrosine-like DOM generation are *** temperature enhances the decomposition of ultraviolet humiclike substance and further stimulates labile DOM bio-mineralization into carbon ***,averaged proportions of amino acid compositions(peak B and T)markedly increase(plike compositions(peak A,M and C)decrease after DOM incubation,suggesting incomplete degradation of refractory DOM from high-molecular to low-molecular weight *** findings support the new notion of the continuous DOM biodegradation in a mode as“steps by steps”,contributing to a new understanding of carbon cycling for the UN Sustainable Development Goal.

关键词： Dissolved organic matter(DOM) Sequential biodegradation Recalcitrant compounds Component and fate Fluorescence analysis

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颈部周围神经源性肿瘤的CT表现

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当代医学 2009年第20期15卷 87-90页

作者：李二妮罗德红赵晶薛梅王振常周纯武中国医学科学院北京协和医学院肿瘤医院影像诊断科北京100021 首都医科大学附属北京同仁医院放射科北京100730

目的分析颈部周围神经源性肿瘤的CT表现,提高对该疾病的诊断水平。方法回顾性总结经手术病理证实的61例颈部神经源性肿瘤的CT表现,患者年龄7～75岁,平均40岁。24例男性,37例女性。9例行平扫,52例行增强扫描。神经鞘瘤34例,副神经节瘤18... 详细信息

目的分析颈部周围神经源性肿瘤的CT表现,提高对该疾病的诊断水平。方法回顾性总结经手术病理证实的61例颈部神经源性肿瘤的CT表现,患者年龄7～75岁,平均40岁。24例男性,37例女性。9例行平扫,52例行增强扫描。神经鞘瘤34例,副神经节瘤18例,神经纤维瘤5例,恶性神经鞘瘤4例。23例可判断肿瘤的神经起源,来自交感神经6例,迷走神经3例,臂丛6例,颈丛5例,舌下神经、面神经及三叉神经各1例。结果43例位于颈动脉间隙,10例位于椎旁间隙,3例位于咀嚼肌间隙,2例咽旁间隙,椎前间隙、腮腺区及枕部皮下各1例。25例神经鞘瘤(25/28,89.3%)增强扫描呈不均匀高低混杂密度。17例颈动脉体瘤,2例为双侧病变,均位于颈动脉分叉水平,17个病灶(17/19,89.5%)使颈内、外动脉夹角增大,11个病灶(11/19,57.9%)包绕颈动脉。4例恶性神经鞘瘤密度不均匀。4例神经纤维瘤增强呈不均匀强化。结论解剖部位及增强扫描强化特点对于颈部周围神经源性肿瘤具有重要的诊断价值。周围血管或肌肉移位对判断肿瘤神经起源有提示作用。

关键词：头颈部神经鞘瘤神经纤维瘤副神经节瘤体层摄影术,X线计算机

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Neural mechanisms of social learning and decision-making

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Science China(life Sciences) 2021年第6期64卷 897-910页

作者： Yinmei ni Jian li School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health Peking UniversityBeijing 100871China

One of the hallmarks of human society is the ubiquitous interactions among ***,a significant portion of human daily routine decision making is socially *** economic theory,namely game theory,has prescribed the canonical decision strategy when"rational"social agents have full information about the decision *** reality,however,social decision is often influenced by the trait and state parameters of selves and ***,understanding the cognitive and neural processes of inferring the decision parameters is pivotal for social decision ***,both correlational and causal non-invasive neuroimaging studies have started to reveal the critical neural computations underlying social learning and decision-making,and highlighted the unique roles of"social"brain structures such as temporal-parietal junction(TPJ)and dorsomedial prefrontal cortex(dmPFC).Here we review recent advances in social decision neuroscience and maintain the focus on how the inference about others is dynamically acquired during social learning,as well as how the prosocial(altruistic)behavior results from orchestrated interactions of different brain regions specified under the social utility *** conclude by emphasizing the importance of combining computational decision theory with the identification of neural mechanisms that represent,evaluate and integrate value related social information and generate decision variables guiding behavioral output in the complex social environment.

关键词： social cognition decision-making reinforcement learning value altruism

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Improving effect on forming quality and accuracy using a polyurethane board positioning/resetting the discrete steel pad in multi-point forming

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International Journal of Minerals,Metallurgy and Materials 2019年第4期26卷 447-459页

作者： er-hu Qu Ming-zhe li Rui li College of Materials Science and Engineering Jilin University Roll Forging Institute Jilin University Changchun Ruiguang Technology Co. Ltd.

To improve the quality of multi-point die forming, a new approach using discrete steel pads was proposed. The formability of three different multi-point die forming processes was analyzed through numerical simulation and experiments. Numerical simulation and experimental results showed that the use of discrete steel pads in the multi-point forming process can substantially improve the stress–strain state on the plate and suppress dimple, straight-edge, and wrinkle defects. This analysis verified that the use of discrete steel pads in a multi-point forming process can effectively improve the quality and accuracy with which sheet metal is formed.

关键词： multi-point forming dimple wrinkle numerical simulation forming accuracy

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Carbon nanotube-based electrodes for flexible supercapacitors

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Nano Research 2020年第7期13卷 1825-1841页

作者： Sheng Zhu Jiangfeng ni Yan li Beijing National Laboratory far Molecular Sciences Key Laboratory for the Physics and Chemistry of NanodevicesState Key Laboratory of Rare Earth Materials Chemistry and ApplicationsCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China School of Physical Science and Technology Center far Energy Conversion Materials&Physics(CECMP)Jiangsu Key Laboratory of Thin FilmsSoochow UniversitySuzhou 215006China

Flexible supercapacitors(SCs)have attracted increasing attention as the power supply unit for portable/wearable *** nanotubes(CNTs)are promising candidate materials for flexible SC electrodes because of their outstanding mechanical property,high electrical conductity,large surface area,and *** can assemble into various macroscopic materials with different *** this review,flexible CNT assemblies including 1D fibers,2D films,and 3D aerogels and sponges are introduced with a focus on the design strategies and fabrication *** recent developments and state-of-the-art applications of such structures as electrodes in flexible SCs are summarized based on device configurations including sandwiched,interdigital in-plane,and cable-type *** flexible CNT-based electrodes have shown great advantages in bendability,stretchability and/or compresisbility,as well as a long cycle *** current challenges and future research opportunities in this field are also discussed.

关键词： carbon nanotubes nanostructures electrodes flexible supercapacitors

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Mass to light ratio of galaxies and gravitational lensing

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Research in Astronomy and Astrophysics 2013年第9期13卷 1041-1051页

作者： Nan li Ran li Xin-Zhong er National Astronomical Observatories Chinese Academy of Sciences

We investigate the potential of constraining the mass to light ratio of field galaxies using weak lensing shear and flexions. A suite of Monte Carlo simulations are used to generate weak lensing observations with different noise models. Using mock data, we find that the inclusion of flexions can improve the estimate of foreground halo parameters, but the details are strongly dependent on noise in the model. In the intrinsic noise limit, both shear and flexions are promising tools to study the mass to light ratio of galaxies. However, if the noise model of flexions follows the form described by Rowe et al., there is only - 5% improvement in the constraints even with next generation lensing observations.

关键词： cosmology: dark matter -- galaxies: halos -- gravitational lensing

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