检索结果-南通市图书馆

Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2019年第2期11卷 244-257页

作者： Sang Bong lee Jae-eon lee Sung Jin Cho Jungwook Chin Sang Kyoon Kim In-Kyu lee Sang-Woo lee Jaetae lee Yong Hyun Jeon New Drug Development Center Daegu-Gyeongbuk Medical Innovation FoundationDaeguSouth Korea Department of Biomaterials Science College of Natural Resources and Life Science/Life and Industry Convergence Research InstitutePusan National UniversityPusanSouth Korea Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease Kyungpook National University HospitalDaegu 702-210South Korea Department of Nuclear Medicine Kyungpook National University HospitalDaegu 702-210South Korea Department of Internal Medicine Kyungpook National University School of MedicineDaegu 700-721South Korea Daegu-Gyeongbuk Medical Innovation Foundation Daegu 360-4South Korea [Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation FoundationDaegu 360-4South Korea

Plasmonic nanostructure-mediated photothermal therapy(PTT) has proven to be a promising approach for cancer treatment,and new approaches for its effective delivery to tumor lesions are currently being *** study aimed to assess macrophage-mediated delivery of PTT using radioiodine-124-labeled gold nanoparticles with crushed gold shells(124I-Au@AuCBs) as a theranostic nanoplatform.124I-Au@AuCBs exhibited effective photothermal conversion effects both in vitro and in vivo and were efficiently taken up by macrophages without *** the administration of 124I-Au@AuCB-labeled macrophages to colon tumors,intensive signals were observed at tumor lesions,and subsequent in vivo PTT with laser irradiation yielded potent antitumor *** results indicate the considerable potential of 124I-Au@AuCBs as novel theranostic nanomaterials and the prominent advantages of macrophage-mediated cellular therapies in treating cancer and other diseases.

关键词： Photothermal therapy Radionuclide crushed gold shell nanoballs Macrophage-mediated delivery

Heuristic solution using decision tree model for enhanced XML schema matching of bridge structural calculation documents

在线全文

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2020年第6期14卷 1403-1417页

作者： Sang IPARK Sang-ho lee Department of Civil Environmental and Architectural EngineeringUniversity of Colorado at BoulderBoulderco 80309USA Department of"Civil and Environmental Engineering Yonsei UniversitySeoul 03722Korea

Research on the quality of data in a structural calculation document(SCD)is lacking,although the SCD ofa bridge is used as an essential reference during the entire lifecycle of the *** Schema matching enables qualitative improvement of the stored *** study aimed to enhance the applicability of XML Schema matching,which improves the speed and quality of information stored in bridge ***,the authors proposed a method of reducing the computing time for the schema matching of bridge *** computing speed of schema matching was increased by 13 to 1800 times by reducing the checking process of the ***,the authors developed a heuristic solution for selecting the optimal weight factors used in the matching process to maintain a high accuracy by introducing a decision *** decision tree model was built using the content elements stored in the SCD,design companies,bridge types,and weight factors as input variables,and the matching accuracy as the target *** inverse-calculation method was applied to extract the weight factors from the decision tree model for high-accuracy schema matching results.

关键词： structural calculation document bridge structure XML Schema matching weight factor data mining decision tree model

Rationally designed graphene channels for real-time sodium ion detection for electronic tongue

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

InfoMat 2023年第7期5卷 43-58页

作者： Chung Won lee Sang eon Jun Seung Ju Kim Tae Hyung lee Sol A.lee Jin Wook Yang Jin Hyuk Cho Shinyoung Choi Cheol-joo Kim Soo Young Kim ho Won Jang Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)PohangRepublic of Korea Advanced Institute of Convergence Technology Seoul National UniversitySuwonRepublic of Korea

Monitoring taste-inducing ions and molecules continuously in liquids or solutions is of great considerable matter for the realization of the electronic tongue(E-tongue).Particularly from the five major tastes,the highly selective,sensitive detection of Na^(+)in real-time is *** is due to the saltiness of food is the key ingredient in most ***,existing Na^(+)detecting devices have relatively low performances of selectivity,sensitivity,and lack of on–off ***,conventional devices significantly deteriorate in capac-ity due to repetitive usage or lifetime shortage by degradation of the sensing ***,a graphene-based channel was rationally designed by the facile decoration of Calix[4]arene and Nafion to address this *** act as a receptor and a molecular sieve,respectively,to enhance selectivity and sensitivity and elon-gate the life expectancy of the *** device was merged with a microfluidic channel to control the injection and withdrawal of solutions to fulfill dynamic on–off *** fabricated device has highly selective,sensitive Na^(+)detection properties compared to other 10 molecule/ionic *** on–off functions of the device were available,also possesses a long lifespan of at least 220 ***,it can precisely discriminate real beverages containing Na^(+),which can be observed by principal component analysis *** features offer the possibility of ascending to a platform for E-tongues in near future.

关键词： electronic tongue graphene microfluidic channels Na^(+)sensors solution-gated field-effect transistors

Thermoresponsive Al^(3+)-crosslinked poly(N-isopropylacrylamide)/alginate composite for green recovery of lithium from Li-spiked seawater

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green Energy & Environment 2022年第2期7卷 334-344页

作者： Sung ho Park Sang Joon lee Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang790-784South Korea

With the rapid increase in the demand for lithium as an energy-critical element,the recovery of Li+ions from seawater is a worldwide challenging ***,we propose a new facile and fast selective recovery approach of Li+using an Al^(3+)-crosslinked poly(N-isopropylacrylamide)(PNIPAAm)/alginate(Alg)(PNP/Alg(Al)) *** in situ TEM images indicate that Alg-Al^(3+)coordination is reorganized via the rearrangement of PNIPAAm and Alg networks,as the temperature *** reorganization eventually leads to the formation of polycrystalline *** in situ FTIR results exhibit that PNP/Alg(Al) composite has peculiar phase transitions,which includes a retrogressive phase change from hydrophobic to *** synergetic effect of the strong repulsion force of Al^(3+) ions and the attractive force of negatively charged polymeric chains enables the efficient adsorption of Li+ions with a low affinity from Li-spiked seawater.7.3% of Li+ions are recovered from Li-spiked seawater although the concentration of Li-spiked seawater is very *** addition,Li+ions can be extracted from PNP/Alg(Al) composite with the use of a small thermal *** proposed thermoresponsive IPN gel provides a strong potential in practical applications for Li+recovery as an innovative energy-material strategy.

关键词： structure seawater lithium

Virtual reconfigurable architecture for evolving combinational logic circuits

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2014年第5期21卷 1862-1870页

作者：王进 lee Chong-ho Chongqing Key Laboratory of Computational Intelligence(Chongqing University of Posts and Telecommunications) Department of Information&Communication Engineering Inha University

A virtual reconfigurable architecture(VRA)-based evolvable hardware is proposed for automatic synthesis of combinational logic circuits at *** proposed VRA is implemented by a Celoxica RC1000 peripheral component interconnect(PCI)board with an Xilinx Virtex xcv2000E field programmable gate array(FPGA).To improve the quality of the evolved circuits,the VRA works through a two-stage evolution: finding a functional circuit and minimizing the number of logic gates used in a feasible *** optimize the algorithm performance in the two-stage evolutionary process and set free the user from the time-consuming process of mutation parameter tuning,a self-adaptive mutation rate control(SAMRC)scheme is *** the evolutionary process,the mutation rate control parameters are encoded as additional genes in the chromosome and also undergo evolutionary *** efficiency of the proposed methodology is tested with the evolutions of a 4-bit even parity function,a 2-bit multiplier,and a 3-bit *** obtained results demonstrate that our scheme improves the evolutionary design of combinational logic circuits in terms of quality of the evolved circuit as well as the computational effort,when compared to the existing evolvable hardware approaches.

关键词： evolutionary algorithm evolvable hardware self-adaptive mutation rate control virtual reconfigurable architecture

Geochemical evaluation of low salinity hot water injection to enhance heavy oil recovery from carbonate reservoirs

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2019年第2期16卷 366-381页

作者： Ji ho lee Kun Sang lee Department of Earth Resources and Environmental Engineering Hanyang University

Although low salinity water injection(LSWI) has recovered residual oil after the conventional waterflood, highly viscous oil has remained in heavy oil reservoirs. hot water injection is an economic and practical method to improve oil mobility for viscous oil reservoirs. It potentially controls temperature-dependent geochemical reactions underlying the LSWI mechanism and oil viscosity. Therefore, this study has modeled and evaluated a hybrid process of low salinity hot water injection(hot LSWI) to quantify synergistic effects in heavy oil reservoirs. In comparison to seawater injection(SWI) and LSWI, hot LSWI results in more cation ion-exchange(Ca^(2+) and Mg^(2+)) and more wettability modification. hot LSWI also reduces oil viscosity. In core-scaled systems, it increases oil recovery by 21% and 6% over SWI and LSWI. In a pilotscaled reservoir, it produces additional oil by 6% and 3% over SWI and LSWI. Probabilistic forecasting with uncertainty assessment further evaluates the feasibility of hot LSWI to consider uncertainty in the pilot-scaled reservoir and observes enhanced heavy oil production. This study confirms the viability of hot LSWI due to synergistic effects including enhanced wettability modification and oil viscosity reduction effects.

关键词： Low salinity water injection hot water injection Wettability modification Geochemical reaction Viscosity reduction

Plasma Post Oxidation of Plasma Nitrocarburized SKD 61 Steel

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2008年第1期24卷 136-138页

作者： Insup lee Kwang-ho Jeong Department of Advanced Materials Engineering Dongeui University Busan 614-714 Korea

Plasma nitrocarburizing and plasma oxidizing treatments were performed to improve the wear and corrosion resistance of SKD 61 *** nitrocarburizing was conducted for 12 h at 540℃in the nitrogen, hydrogen and methane atmosphere to produce theε-Fe-（2-3）（N,C） *** compound layer produced by plasma nitrocarburising was predominantly composed ofε-phase,with a small proportion ofγ′-Fe-4 （N,C） phase. The thickness of the compound layer and the diffusion layer are about 10μm and about 200μm,respectively. Plasma post oxidation was performed on the nitrocarburized samples with various oxygen/hydrogen ratio at constant temperature of 500℃for 1 *** very thin magnetite （Fe-3O-4） layer of 1-2μm in thickness on top of the compound layer was *** polarization test revealed that plasma nitrocarburizing process contributed a significant improvement of corrosion resistance of SKD 61 ***,the corrosion characteristics of the nitrocarburized compound layer was deteriorated by oxidation treatment.

关键词： Plasma nitrocarburizing Post oxidation ε-Fe2-3(N,C) γ′-Fe4(N,C) Fe3O4

Pancreatic parenchymal injection of ethanol and octreotide to induce focal pancreatic fibrosis in rats: Strategies to eliminate postoperative pancreatic fistula

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2018年第1期17卷 81-85页

作者： Soo ho lee Tae ho hong Department of Surgery Uijeongbu St.Mary’s Hospital College of Medicine The Catholic University of Korea Department of Surgery Seoul St.Mary’s Hospital College of Medicine The Catholic University of Korea

Background: Postoperative pancreatic fistula(POPF) is more likely to occur in a soft pancreas compared to a hard pancreas in which fibrosis has progressed. There is almost no leakage at the anastomosis site or cut surface of a hard pancreas. The aim of this study was to induce localized fibrosis at the cut surface of the pancreas in a rat ***: Thirty-six rats were divided into three groups(group S: normal saline group; group E: ethanol group; and group O: octreotide group). Each rat was directly injected with a particular compound at the duodenal lobe of the pancreatic parenchyma. Each group was divided into three subgroups according to the time of post-injection sacrifice(1, 2, or 4 weeks). The hardness, suture holding capacity(SHC), and histological fibrosis grade of each pancreas were ***: The hardness, SHC, and fibrosis grade of groups E and O were increased at week 1, with greater increases in group E(all P < 0.001). In a subgroup comparison, the hardness, SHC, and fibrosis grade of group E tended to decrease gradually over time, with no regular pattern evident in group O. A comparison between the injected site(duodenal lobe) and non-injected site(splenic lobe) of the pancreas revealed increases in the three parameters of group E only in the duodenal lobe, with increases in group O at both the duodenal and splenic ***: Parenchymal injection of ethanol and octreotide increased pancreatic fibrosis. Unlike octreotide, ethanol provoked localized fibrosis that was maintained over time. It is expected that ethanol injection could eliminate POPF during pancreatic surgery.

关键词： Ethanol Octreotide Pancreatic fibrosis Pancreatic fistula Rat model

Development of a Biomimetic Quadruped Robot

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2007年第4期4卷 193-199页

作者： Thanhtam ho Sunghac Choi Sangyoon lee Department of Mechanical Design and Production Engineering Konkuk University Seoul 143-701 Korea

This paper presents the design and prototype of a small quadruped robot whose walking motion is realized by two piezocomposite actuators. In the design, biomimetic ideas are employed to obtain the agility of motions and sustainability of a heavy load. The design of the robot legs is inspired by the leg configuration of insects, two joints （hip and knee） of the leg enable two basic motions, lifting and stepping. The robot frame is designed to have a slope relative to the horizontal plane, which makes the robot move forward. In addition, the bounding locomotion of quadruped animals is implemented in the robot. Experiments show that the robot can carry an additional load of about 100 g and run with a fairly high velocity. The quadruped prototype can be an important step towards the goal of building an autonomous mobile robot actuated by piezocomposite actuators.

关键词： quadruped robot piezocomposite actuator bounding locomotion