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Favorable surgical treatment outcomes for chronic constipation with features of colonic pseudo-obstruction

World Journal of Gastroenterology 2012年第32期18卷 4441-4446页

作者： eon chul han Heung-Kwon Oh Heon-Kyun Ha Eun Kyung Choe Sang Hui Moon Seung-Bum Ryoo Kyu Joo Park Department of Surgery Seoul National University College of MedicineSeoul 110-744South Korea Seoul National University Hospital Gangnam Center Seoul 110-744South Korea

AIM:To determine long-term outcomes of surgical treatments for patients with constipation and features of colonic ***:Consecutive 42 patients who underwent surgery for chronic constipation within the last 13 years were prospectively *** identified a subgroup with colonic pseudo-obstruction(CPO) features,with dilatation of the colon proximal to the narrowed transitional zone,in contrast to typical slowtransit constipation(STC),without any dilated colonic *** outcomes of surgical treatments for chronic constipation with features of CPO were analyzed and compared with outcomes for ***:Of the 42 patients who underwent surgery for constipation,33 patients had CPO with dilatation of the colon proximal to the narrowed transitional *** were 16 males and 17 females with a mean age of 51.2 ± 16.1 *** had symptoms of chronic intestinal obstruction,including abdominal distension,pain,nausea,or vomiting,and the mean duration of symptoms was 67 mo(range:6-252 mo).Preoperative defecation frequency was 1.5 ± 0.6 times/wk(range:1-2 times/wk).Thirty-two patients underwent total colectomy,and one patient underwent diverting transverse *** was no surgery-related *** histologic examination showed hypoganglionosis or agangliosis in 23 patients and hypoganglionosis combined with visceral neuropathy or myopathy in 10 *** contrast,histology of STC group revealed intestinal neuronal dysplasia type B(n = 6) and visceral myopathy(n = 3).Early postoperative complications developed in six patients with CPO;wound infection(n = 3),paralytic ileus(n = 2),and intraabdominal abscess(n = 1).Defecation frequencies 3 mo after surgery improved to 4.2 ± 3.2 times/d(range:1-15 times/d).Long-term follow-up(median:39.7 mo) was available in 32 patients;all patients had improvements in constipation symptoms,but two patients needed intermittent medication for management of *** 32 patients had distinct

关键词： Constipation Total colectomy Pseudoobstruction Surgical outcome Hypoganglionosis

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Complications after ileal pouch-anal anastomosis in Korean patients with ulcerative colitis

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World Journal of Gastroenterology 2014年第23期20卷 7488-7496页

作者： Seung-Bum Ryoo Heung-Kwon Oh eon chul han Heon-Kyun Ha Sang Hui Moon Eun Kyung Choe Kyu Joo Park Division of Colorectal Surgery Department of SurgerySeoul National University College of MedicineSeoul 110-744South Korea Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam CenterSeoul 135-984South Korea

AIM: To investigate the outcomes of treatments for complications after ileal pouch-anal anastomosis (IPAA) in Korean patients with ulcerative colitis.

关键词： Ulcerative colitis Ileal pouch-anal anastomosis Complications Pouch failure Pouch function

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Surgical management of colonic diverticular disease:Discrepancy between right- and left-sided diseases

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World Journal of Gastroenterology 2014年第29期20卷 10115-10120页

作者： Heung-Kwon Oh eon chul han Heon-Kyun Ha Eun Kyung Choe Sang Hui Moon Seung-Bum Ryoo Seung-Yong Jeong Kyu Joo Park Division of Colorectal Surgery Department of SurgerySeoul National University College of Medicine

AIM:To compare the outcome of the surgical management of left-sided and right-sided diverticular ***:The medical records of 77 patients who were surgically treated for diverticular disease between 1999 and 2010 in a tertiary referral hospital were retrospectively *** study population was limited to cases wherein the surgical specimen was confirmed as diverticulosis by *** diverticula were classified as those arising from the cecum,ascending colon,and transverse colon,and those from the descending colon,sigmoid colon,and rectum were classified as left-sided *** assess the changing trend of occurrence of diverticulosis,data were compared with two previous studies of 51 ***:The proportion of left-sided disease cases was significantly increased compared to the results of our previous studies in 1994 and 2001,(27.5%vs48.1%,P<0.05).Moreover,no differences in gender,body mass index,multiplicity of the diverticula,fever,or leukocytosis were noted between patients with rightsided and left-sided ***,patients with right-sided disease were significantly younger(50.9year vs 64.0 year,P<0.01).Furthermore,left-sided disease was significantly associated with a higher incidence of complicated diverticulitis(89.2%vs 57.5%,P<0.01),combined resection due to extensive inflammation(21.6%vs 5.0%,P<0.05),operative complications(51.4%vs 27.5%,P<0.05),and in-hospital mortality(10.8%vs 0%,P<0.05),along with longer post-operative hospitalization duration(21.3±10.2 d vs 10.6±8.1 d,P<0.05).CONCLUSION:Compared with right-sided diverticular disease,the incidence of left-sided disease in Korea has increased since 2001 and is associated with worse surgical outcomes.

关键词： Colonic diverticulosis Diverticular bleeding Diverticulitis Poor surgical outcome Left-sided diverticulitis

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UBVVI Surface Photometry of the Spiral Galaxy NGC 300 in the Sculptor Group

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Chinese Journal of Astronomy and Astrophysics 2004年第4期4卷 299-310页

作者： Sang chul Kim Hwankyung Sung Hong Soo Park eon-Chang Sung Korea Astronomy Observatory Taejon 305-348Republic of KoreaDepartment of Astronomy and Space ScienceSejong University98 Gunja-dongGwangjin-guSeoul 143-747Republic of KoreaAstronomy ProgramSEESSeoul National UniversitySeoul 151-742Republic of KoreaKorea Astronomy ObservatoryTaejon 305-348Republic of Korea

We present UBVI surface photometry over a 20.5' × 20.5' area of the late-type spiral galaxy NGC 300. We have derived isophotal maps, surface brightness profiles, ellipticity profiles, position angle profiles, and color profiles. By merging our I-band measurements with those of Boker et al. based on Hubble Space Telescope observations, we have obtained combined I-band surface brightness profiles for the region 0.02' < r < 500' and have decomposed the profiles into three components: a nucleus, a bulge, and an exponential disk.

关键词： galaxies: spiral - galaxies: photometry - galaxies: individual(NGC 300) - galaxies: nuclei

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Entransy and Exergy Analyses for Optimizations of Heat-Work Conversion with Carnot Cycle

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Journal of Thermal Science 2016年第3期25卷 242-249页

作者： chul Ho han Kyoung Hoon Kim Department of Mechanical System Engineering Kumoh National Institute of Technology Department of Mechanical Engineering Kumoh National Institute of Technology

The concept of entransy has been newly proposed in terms of the analogy between heat and electrical conduction and could bc useful in analyzing and optimizing the heat-work conversion systems. This work presents comparative analyses of entransy and exergy for optimizations of heat-work conversion. The work production and heat transfer processes in Carnot cycle system are investigated with the formulations of exergy destruction, entransy loss, work entransy, entransy dissipation, and cfficiencics for both cases of dumping and non-dumping of used source fluid. The effects of source and condensation temperatures on the system performance arc systematically investigated for optimal condition of producing maximum work or work cntransy.

关键词： entransy exergy heat-work conversion Carnot cycle efficiency

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Exergetical Analysis of Organic Flash Cycle with Two-Phase Expander for Recovery of Finite Thermal Reservoirs

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Journal of Thermal Science 2014年第6期23卷 572-579页

作者： chul Ho han Kyoung Hoon Kim Department of Intelligent Mechanical Engineering Kumoh National Institute of TechnologyDaehakro 61GumiGyeongbuk 730-701Korea Department of Mechanical Engineering Kumoh National Institute of TechnologyDaehakro 61GumiGyeongbuk 730-701Korea

In this work exergetical performance analysis is carried out based on the second law of thermodynamics for organic flash cycle(OFC) using a two-phase expander instead of throttle expansion in order to recover efficiently finite thermal *** exergy destructions(anergies) at various components of the system are theoretically investigated as well as the exergy *** show that the anergy of heat exchanger or two-phase expander decreases while the anergy of throttle valve increases with increasing flash temperature,and the exergy efficiency has an optimum value with respect to the flash *** the optimal conditions with respect to the flash temperature,exergy efficiency increases with the heating temperature and the component having the largest exergy destruction varies with the flash temperature or heating temperature.

关键词： organic flash cycle(OFC) low grade heat source exergy anecgy

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EMMS drag model for simulating a gas-solid fluidized bed of geldart B particles: Effect of bed model parameters and polydisperity

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Particuology 2020年第4期18卷 142-154页

作者： Krishnadash SKshetrimayum Seongho Park Chonghun han chul-Jin Lee School of Chemical Engineering and Materials Science Chung-Ang University06974 SeoulSouth Korea School of Chemical and Biological Engineering Seoul National UniversitySan 56-1Shillim-dongKwanak-guSeoul151-742South Korea

The energy minimization multi-scale(EMMS)is a heterogeneous drag model widely used to simulate gas-solid fluidized *** this work,we conducted computational fluid dynamics simulations of a gas-solid fluidized bed for Geldart B particles to compare the EMMS with the homogeneous Gidaspow drag *** results from both the homogeneous and heterogeneous drag models were compared with literature experimental data on pressure drop and bed *** was no noticeable difference in predicted bed characteristics in the slugging ***,in the turbulent regime,the EMMS model predicted slightly lower bed expansion than did the Gidaspow *** evaluated the effects of solid-solid and solid-wall interaction parameters by varying the restitution and specularity *** expansion increases by a factor of 1.05-1.08 when the restitution coefficient increases from 0.9 to *** models predict a higher solid volume fraction and higher solid downflow velocity near the wall for a low specularity coefficient of 0.01 or *** we considered solid phases of different sizes to model polydisperity,the simulation predicted vertical segregation of 300,350,and 400μm in the fluidized region due to ***,the drag models made similar predictions in bad characteristics from cold model simulation ofa polysilicon fluidized-bed reactor,although there was very little vertical segregation of solid particles for this case.

关键词： CFD simulation Energy minimization multi-scale drag Gas-solid fluidized bed Polydisperity Fluidized-bed reactor

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THE PHYSICAL PROPERTIES OF POLY(2-HYDROXYETHYL METHACRYLATE)COPOLYMER HYDROGELS USED AS INTRAVAGINAL RINGS

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Chinese Journal of Polymer Science 2009年第3期27卷 359-366页

作者： Young A han Eun Mi Lee Byung chul Ji Department of Textile System Engineering Kyungpook National UniversityDaegu 702-701Korea Department of Advanced Organic Materials Science and Engineering Kyungpook National UniversityDaegu 702-701Korea

Poly(2-hydroxyethyl methacrylate)(PHEMA)and poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) [P(HEMA-co-SMA)]hydrogels with different compositions were prepared to be used as intravaginal rings,and their gelation time,water content,mechanical properties and morphology were *** water content of PHEMA and P(HEMA-co-SMA) hydrogels decreased as the concentration of the monomer and the degree of crosslinking increased,while the water content significantly increased as the content of SMA,the hydrophilic monomer,*** increasing of the concentration of the crosslinking agent affected the tensile and flexural properties *** presence of a proper small amount of SMA also led the tensile and flexural modulus to move to a higher *** results showed that P(HEMA-co-SMA) hydrogel with high drug load and good mechanical properties at optimum preparation conditions can be prepared for intravaginal rings to deliver nonhormonal *** results may be applied to prepare better intravaginal drug delivery devices.

关键词： PHEMA and P(HEMA-co-SMA)hydrogels Tensile and flexural properties High drug load Intravaginal drug delivery devices.

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Germline-competent stem cell in avian species and its application

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Asian Journal of Andrology 2015年第3期17卷 421-426页

作者： Jae Yong han Hyung chul Lee Tae Sub Park Department of Agricultural Biotechnology College of Agriculture and Life Sciences and Research Institute of Agriculture and Life Sciences Seoul National University Seoul 151-921 Korea Graduate School of International Agricultural Technology and Institute of Green-Bio Science and Technology Seoul National University Pyeongchang-gun Gangwon-do 232-916 Korea

Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to,the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.

关键词： birds germline-competent stem cells primordial germ cells spermatogonial stem cells

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Coupled CUBIC Congestion Control for MPTCP in Broadband Networks

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Computer Systems Science & Engineering 2023年第4期45卷 99-115页

作者： Jae Yong Lee Byung chul Kim Youngmi Kwon Kimoon han Department of Information and Communications Engineering Chungnam National UniversityDaejeon34134Korea Agency for Defense Development Daejeon34186Korea

Recently,multipath transmission control protocol(MPTCP)was standardized so that data can be transmitted through multiple paths to utilize all available path ***,when high-speed long-distance networks are included in MPTCP paths,the traffic transmission performance of MPTCP is severely deteriorated,especially in case the multiple paths’characteristics are heavily *** order to alleviate this problem,we propose a“Coupled CUBIC congestion control”that adopts TCP CUBIC on a large bandwidth-delay product(BDP)path in a linked increase manner for maintaining fairness with an ordinary TCP traversing the same bottleneck *** verify the performance excellence of the proposed algorithm,we implemented the Coupled CUBIC Congestion Control into Linux kernels by modifying the legacy MPTCP linked-increases algorithm(LIA)congestion control source *** constructed asymmetric heterogeneous network testbeds mixed with large and small BDP paths and compared the performances of LIA and Coupled CUBIC by *** results show that the proposed Coupled CUBIC utilizes almost over 80%of the bandwidth resource in the high BDP path,while the LIA utilizes only less than 20%of the bandwidth for the same *** was confirmed that the resource utilization and traffic transmission performance have been greatly improved by using the proposed Coupled CUBIC in high-speed multipath networks,as well as maintaining MPTCP fairness with competing single-path CUBIC or Reno TCP flows.

关键词： MPTCP congestion control Coupled CUBIC high BDP network

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