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Effect of corneal light scatter on vision: a review of the literature

International Journal of Ophthalmology(English edition) 2016年第3期9卷 459-464页

作者： Leopoldo Spadea Giorgia Maraone Francesca Verboschi enzo maria vingolo Daniele Tognetto Department of Biotechnology and Medical-Surgical Sciences "Sapienza" University of Rome Eye Clinic Ospedale MaggioreUniversity of Trieste

The cornea is the transparent connective tissue window at the front of the *** physiological role of the cornea is to conduct external light into the eye,focus it,together with the lens,onto the retina,and to provide rigidity to the entire ***,good vision requires maintenance of the transparency and proper refractive shape of the *** surface structures irregularities can be associated with wavefront aberrations and scattering *** scattering in the human cornea causes a reduction of visual *** fact,the cornea must be transparent and maintain a smooth and stable curvature since it contributes to the major part of the focusing power of the *** most cases,a simple examination of visual acuity cannot demonstrate the reduction of visual quality secondary light *** fact,clinical techniques for examining the human cornea in vivo have greatly expanded over the last few *** measurement of corneal back scattering qualifies the degree of corneal *** measurement of corneal forward-scattering quantifies the amount of visual impairment that is produced by the alteration of *** aim of this study was to review scattering in the human cornea and methods of measuring it.

关键词： cornea haze light photorefraetive keratectomy scattering vision

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Long term results of no- alcohol laser epithelial keratomileusis and photorefractive keratectomy for myopia

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International Journal of Ophthalmology(English edition) 2015年第3期8卷 574-579页

作者： Leopoldo Spadea Francesca Verboschi Vittoria De Rosa Mariella Salomone enzo maria vingolo Department of Medico-Surgical Sciences and Biotechnologies Sapienza University of Rome

AIM: To evaluate the long term clinical results of mechanical no-alcohol-assisted laser epithelial keratomileusis(LASEK) versus standard photorefractive keratectomy(PRK) for low-moderate ***: Twenty-five eyes treated with LASEK and twenty-five eyes treated with PRK were evaluated with a mean follow-up duration of 60 mo. Mechanical separation of the epithelium was performed with blunt spatula and without application of alcohol. Laser ablation was performed with the MEL-70 excimer laser. All patients were examined daily until epithelial closure; at 1, 3, 6,and 12 mo, and every year subsequently. Main outcome measures were uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA),manifest refraction, haze, efficacy and safety ***: Twenty-one eyes and 22 eyes completed follow-up of 60 mo in LASEK and PRK group respectively. Manifest refraction at 60 mo follow-up was-0.01 and 0.26 in LASEK and PRK group respectively. In the LASEK group mean UDVA and mean CDVA after60 mo were 20/22 and 20/20 respectively(P >0.01). In the PRK group mean UDVA and mean CDVA at 60 mo follow-up were 20/20 and 20/20 after 60mo(P >0.01). The efficacy indexes were 0.87 and 0.95, and the safety indexes were1.25 and 1.4 respectively for LASEK group and PRK ***: Both standard PRK and no-alcohol LASEK offer safe and effective correction of low-moderate myopia in the long term without any statistically significant difference between the two groups.

关键词： alcohol laser epithelial keratomileusis myopia photorefractive keratectomy

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Massive carcinoma of the cornea in an immunocompetent patient

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Health 2011年第4期3卷 245-248页

作者： Irene Pecorella Pierluigi Grenga enzo maria vingolo 不详

A case of massive well-differentiated, superficially invasive, squamous cell carcinoma of the cornea is described. This patient did not have any common identifiable risk factors in the development of SCC of the ocular surface, such as excessive solar exposure, HPV infection, immunocompromised state, or chronic ocular irritation. A perforating injury in the cornea of the same eye had occurred 11 years before. The possible role of trauma in causing subsequent neoplastic development is discussed, as well as the immunohistochemical results for p53 and p63.

关键词： Squamous Cell Carcinoma Cornea HPV Trauma Solar Elastosis

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