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Quantitative phase imaging based on holography:trends and new perspectives

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Light(Science & Applications) 2024年第7期13卷 1235-1277页

作者： Zhengzhong Huang Liangcai cao Department of Precision Instrument Tsinghua UniversityBeijing 100084China

In 1948,Dennis Gabor proposed the concept of holography,providing a pioneering solution to a quantitative description of the optical *** 75 years of development,holographic imaging has become a powerful tool for optical wavefront measurement and quantitative phase *** emergence of this technology has given fresh energy to physics,biology,and materials *** holography(DH)possesses the quantitative advantages of wide-field,non-contact,precise,and dynamic measurement capability for *** has unique capabilities for the propagation of optical fields by measuring light scattering with phase *** offers quantitative visualization of the refractive index and thickness distribution of weak absorption samples,which plays a vital role in the pathophysiology of various diseases and the characterization of various *** provides a possibility to bridge the gap between the imaging and scattering *** propagation of wavefront is described by the complex *** complex-value in the complex-domain is reconstructed from the intensityvalue measurement by camera in the ***,we regard the process of holographic recording and reconstruction as a transformation between complex-domain and real-domain,and discuss the mathematics and physical principles of *** review the DH in underlying principles,technical approaches,and the breadth of *** conclude with emerging challenges and opportunities based on combining holographic imaging with other methodologies that expand the scope and utility of holographic imaging even *** multidisciplinary nature brings technology and application experts together in label-free cell biology,analytical chemistry,clinical sciences,wavefront sensing,and semiconductor production.

关键词： holographic phase precise

Germ layer formation during Xenopus embryogenesis: the balance between pluripotency and differentiation

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Science China(Life Sciences) 2015年第4期58卷 336-342页

作者： cao Ying Model Animal Research Center of Nanjing University and MOE Key Laboratory of Model Animals for Disease Study

The African clawed frog, Xenopus laevis, has long been a model animal for the studies in the fields of animal cloning, developmental biology, biochemistry, cell biology, and physiology. With the aid of Xenopus, major molecular mechanisms that are involved in embryonic development have been understood. Germ layer formation is the first event of embryonic cellular differentiation, which is induced by a few key maternal factors and subsequently by zygotic signals. Meanwhile, another type of signals, the pluripotency factors in ES cells, which maintain the undifferentiated state, are also present during early embryonic cells. In this review, the functions of the pluripotency factors during Xenopus germ layer formation and the regulatory relationship between the signals that promote differentiation and pluripotency factors are discussed.

关键词： Xenopus germ layer formation pluripotency factors ES cells

Detecting large-scale underwater cracks based on remote operated vehicle and graph convolutional neural network

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Frontiers of Structural and Civil Engineering 2022年第11期16卷 1378-1396页

作者： Wenxuan cao Junjie LI Faculty of Infrastructure Engineering Dalian University of TechnologyDalian 116024China College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing 210098China

It is of great significance to quickly detect underwater cracks as they can seriously threaten the safety of underwater *** to date has mainly focused on the detection of above-water-level cracks and hasn’t considered the large scale *** this paper,a large-scale underwater crack examination method is proposed based on image stitching and *** addition,a purpose of this paper is to design a new convolution method to segment underwater *** improved As-Projective-As-Possible(APAP)algorithm was designed to extract and stitch keyframes from *** graph convolutional neural network(GCN)was used to segment the stitched *** GCN’s m-IOU is 24.02%higher than Fully convolutional networks(FCN),proving that GCN has great potential of application in image segmentation and underwater image *** result shows that the improved APAP algorithm and GCN can adapt to complex underwater environments and perform well in different study areas.

关键词： underwater cracks remote operated vehicle image stitching image segmentation graph convolutional neural network

Dynamic Setting Method of Assessment Indicators for Power Curves of Renewable Energy Sources Considering Scarcity of Reserve Resources

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 101-114页

作者： Minghao cao Jilai Yu the Department of Electrical Engineering Harbin Institute of TechnologyHarbinChina

With the increasing proportion of renewable energy sources(RESs)in power grid,the reserve resource(RR)scarcity for correcting power deviation of RESs has become a potential ***,the power curve of RES needs to be more rigorously *** RR scarcity varies during different time periods,so the values of assessment indicators should be dynamically *** assessment indicators in this paper include two aspects,i.e.,deviation exemption ratio and penalty ***,this paper proposes a method for dynamically calculating the supply capacity and RR cost,primarily taking into account the operating status of thermal units,forecast information of RES,and load ***,after clarifying the logical relationship between the degree of RR scarcity and the values of assessment indicators,this paper establishes a mapping function between *** on this mapping function,a dynamic setting method for assessment indicators is *** the future,RES will generally be equipped with battery energy storage systems(BESSs).Reasonably utilizing BESSs to reduce the power deviation of RESs can increase the expected income of ***,this paper proposes a power curve optimization strategy for RESs considering self-owned *** case study demonstrates that the dynamic setting method of assessment indicators can increase the revenue of RESs while ensuring that the penalty fees paid by RESs to the grid are sufficient to cover the RR ***,the power curve optimization strategy can help RESs further increase income and fully utilize BESSs to reduce power deviation.

关键词： Renewable energy battery energy storage system(BESS) power curve assessment reserve service parameter setting

Reliability-based design of lining structures for underground space against water seepage

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Underground Space 2021年第3期6卷 290-299页

作者： cao Wang Department of Civil Engineering Monash UniversityClaytonVIC 3800Australia School of Civil Engineering The University of SydneySydneyNSW 2006Australia

The use of underground spaces is becoming increasingly important in this era of rapid urbanization and population ***,underground spaces are susceptible to water ingress,which may trigger the deterioration of their structural performance and reduce their *** highlights the importance of the proper design of lining structures with an emphasis on water *** study develops a reliability-based approach to guide the design of lining structures used for underground *** equivalent depth of water seepage is considered for a two-dimensional lining structure in the presence of the randomness and spatial correlation of the water seepage *** probabilistic behavior of the equivalent seepage depth that is derived serves as the basis for reliability-based design of lining structures.A simple design criterion is *** example is presented to demonstrate the applicability of the proposed approach.

关键词： Reliability-based design Spatial correlation Underground space Lining structure Water penetration Serviceability

Environmental pollution and DNA methylation： carcinogenesis, clinical significance, and practical applications

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Frontiers of Medicine 2015年第3期9卷 261-274页

作者： Yi cao Laboratory of Molecular and Experimental Pathology Kunming Institute of Zoology Chinese Academy of Sciences Kunming 650223 China

Environmental pollution is one of the main causes of human cancer. Exposures to environmental carcinogens result in genetic and epigenetic alterations which induce cell transformation. Epigenetic changes caused by environmental pollution play important roles in the development and progression of environmental pollution-related cancers. Studies on DNA methylation are among the earliest and most conducted epigenetic research linked to cancer. In this review, the roles of DNA methylation in carcinogenesis and their significance in clinical medicine were summarized, and the effects of environmental pollutants, particularly air pollutants, on DNA methylation were introduced. Furthermore, prospective applications of DNA methylation to environmental pollution detection and cancer prevention were discussed.

关键词： environmental pollution DNA methylation cancer biomarker diagnosis therapy prevention

Explicit Reciprocity Law for Lubin-Tate Formal Groups

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1399-1412页

作者： Lei cao School of Mathematical Sciences Peking University Beijing 100871 P. R. China

In this article, using Fontaine＇s ФГ-module theory, we give a new proof of Coleman＇s explicit reciprocity law, which generalizes that of Artin-Hasse, Iwasawa and Wiles, by giving a complete formula for the norm residue symbol on Lubin-Tate groups. The method used here is different from the classical ones and can be used to study the Iwasawa theory of crystalline representations.

关键词： ФГ-module Formal groups explicit reciprocity law Kummer map

Numerical interpretation of transient permeability test in tight rock

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第1期10卷 32-41页

作者： Chong cao Department of Civil Engineering and Applied Mechanics McGill University

Pulse-decay method has been widely used to estimate the fluid transport properties of low-permeability geomaterials. In this context, radial flow transient pulse test is conducted to measure the water permeability of Cobourg limestone hollow cylinder. The proposed method applies hydraulic pulses to the sealed central cavity and then the cavity pressure dissipates as the fluid migrates into the saturated rock matrix. The influence of entrapped air bubbles within the pressurized cavity is crucial to interpreting permeability from transient pulse test. The modeling results indicate that the air inclusions can significantly increase the fluid compressibility and thus delay the hydraulic pulse decay process, which may lead to the underestimation of the rock permeability.

关键词： Pulse-decay method Low-permeability Air-water mixture Compressibility

Mesoscopic-Scale Numerical Investigation Including the Influence of Process Parameters on LPBF Multi-Layer Multi-Path Formation

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Computer Modeling in Engineering & Sciences 2021年第1期126卷 5-23页

作者： Liu cao Institute for Systems Rheology School of Mechanical and Electrical EngineeringGuangzhou UniversityGuangzhou Higher Education Mega CenterGuangzhou510006China

As a typical laser additive manufacturing technology,laser powder bed fusion(LPBF)has achieved demonstration applications in aerospace,biomedical and other ***,how to select process parameters quickly and reasonably is still themain concern of LPBF *** order to quantitatively analyze the influence of different process parameters(laser power,scanning speed,hatch space and layer thickness)on the LPBF process,the multilayer and multi-path forming process of LPBF was predicted based on the open-source discrete element method framework Yade and the open-source finite volume method framework *** on the design of experiments method,a four-factor three-level orthogonal test scheme was designed,and the porosity and surface roughness data of each calculation scheme were *** analyzing the orthogonal test data,it was found that as the laser power increased,the porosity decreased,and as the scanning speed,hatch space,and layer thickness increased,the porosity *** addition,the influence of laser power and scanning speed on surface roughness showed a trend of decreasing first and then increasing,while the influence of scanning distance and layer thickness on surface roughness showed amonotonous increasing *** order of the influence of each process parameter on porosity was:scanning speed>laying thickness>laser power>hatch space,and the order of the influence of each process parameter on surface roughness was:hatch space>layer thickness>laser power>scanning *** the porosity of the part is most sensitive to scanning speed,and the surface roughness is the most sensitive to hatch *** above conclusions are expected to provide process control basis for actual LPBF production of the 316L stainless steel alloy.

关键词： Laser powder bed fusion process parameter porosity surface roughness orthogonal test method numerical simulation