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International Journal of Geosciences 2012年第5期3卷 899-907页

作者： enner alcantara Department of Cartography Sao Paulo State University (UNESP) Presidente Prudente Brazil

The objective of this work is to evaluate the feasibility of moderate resolution satellite data estimating the surface heat balance in a tropical hydroelectric reservoir. Each component of the heat flux balance was computed using the MODIS (Moderate Resolution Imaging Spectroradiometer) water surface temperature (WST) level 2, 1 km nominal resolution data (MOD11L2, version 5) from 2003 to 2008. The consequence of the heat flux exchange in the water column thermal structure is also investigated. The passage of cold front over a region decreases the atmospheric pressure and air temperature, enhancing the relative humidity. The sensible flux presents a small variability but an increase occurs due to a convective turbulence caused by front passage. The latent flux decrease but insufficiently to cause a condensation, just the evaporation decreases. The upwelling events are the responsible to maintain the loss of heat after the cold front pas- sage.

关键词： Thermal Infrared Heat and Cooling Mixing Stratification

Disaster risk reduction in mountain areas: a research overview

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Journal of Mountain Science 2022年第6期19卷 1487-1494页

作者： alcantara-AYALA Irasema CUI Peng PASUTO Alessandro Institute of Geography National Autonomous University of Mexico(UNAM)Mexico City 04510Mexico Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610041China CNR-IRPI Research Institute for Geo-Hydrological ProtectionC.so Stati UnitiPadova 435127Italy.

This paper gives an account of the diverse dimensions of research on disaster risk reduction in mountain regions derived from an open call of the Journal of Mountain Science that brought 21 *** special issue includes topics as diverse as landslide dynamics and mechanisms,landslide inventories and landslide susceptibility models,insights to landslide hazards and disasters and mitigation measures,disaster response and disaster risk *** overall structure of the paper takes the form of three *** first part begins by laying out the significance of disaster risk reduction in mountain areas,whereas the second one looks at the research insights on disaster risk reduction in mountains provided by the contributions comprised in the special *** final section identifies areas for further research.

关键词： disaster risk reduction hazards integrated disaster risk management mitigation measures response mountains

Effectiveness of traffic light system on Brazilian consumers perception of food healthfulness

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Food Science and Human Wellness 2019年第4期8卷 368-374页

作者： Mayara Lima Marcela de alcantara Amauri Rosenthal Rosires Deliza IT/DTA–Federal Rural University of Rio de Janeiro BR 465–Km 07CEP 23.890-000SeropédicaRJBrazil Nutrition and Dietetics Department–Federal Fluminense University Rua Mário Santos Braga30CEPNiteróiRJBrazil PDJ-CNPq/Embrapa Agroindústria de Alimentos Av.das Américas29501CEP 23.020-470Rio de JaneiroRJBrazil Embrapa Agroindústria de Alimentos Av.das Américas29501CEP 23.020-470Rio de JaneiroRJBrazil

Front-of-package(FOP)nutrition labelling schemes were developed to improve consumer’s comprehension about the food nutrients associated with non-communicable diseases(NCDs).Several FOPs have already been developed,and Brazil is in the process of evaluating a scheme to introduce in the *** aim of this study was to investigate the impact of TLS,the scheme proposed by the food industry,on the product healthfulness perception.A study with 141 participants was carried out.A conjoint task was designed considering three categories and levels:types of dairy products(light yogurt,prato cheese,and chocolate flavoured milk),Traffic Light System(yes ***)and brand(well-known ***).The effect of TLS on perceived healthfulness was evaluated using a 9-point scales(1:not healthy;9:very healthy).Results showed that the inclusion of TLS did not influence the perceived healthfulness of the products by consumers,even among consumers with higher interest in healthy *** findings suggest that the proposal supported by the food industry does not seem to be the most appropriate,being recommended the development of further studies to compare the efficacy of TLS and other FOP schemes.

关键词： Front of pack Traffic light system Healthfulness perception Food products

Synaptic pathology in multiple sclerosis:a role for Nogo-A signaling in astrocytes?

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Neural Regeneration Research 2023年第1期18卷 127-128页

作者： Sheila Espírito-Santo Vinícius Gabriel Coutinho Flávia Carvalho alcantara Gomes Laboratório de Biologia Celular e Tecidual Universidade Estadual do Norte Fluminense Darcy RibeiroCampos dos GoytacazesRJBrazil Laboratório de Neurobiologia Celular Universidade Federal do Rio de JaneiroInstituto de Ciências BiomédicasRio de JaneiroRJBrazil

Multiple sclerosis(MS)is characterized as an inflammatory demyelinating disease that affects the central nervous system(CNS),leading to sensory,motor and cognitive ***,axonal denudation culminates in axonal lesions and *** demyelinating lesions in MS are associated with infiltration of immune cells combined with activation of the resident CNS inflammatory cells,astro-and microglia.

关键词： sclerosis impairment lesions

Axillary recurrence after intramammary sentinel lymph nodes metastases with capsular extravasation

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Journal of Cancer Metastasis and Treatment 2019年第1期4卷 13-17页

作者： Paulo R.De alcantara Filho Stephania Martins Bezerra Breast Surgery Department Hospital Sirio-LibanesSao Paulo 01308-050Brazil Pathology Department ACCamargo Cancer CenterSao Paulo 01509-010Brazil

Axillary recurrence is a rare event in patients treated with sentinel lymph node biopsy alone with the majority occurring in the first 5 years after surgery. Intramammary lymph node (IMLN) can be the primary sites of metastasis and sentinel lymph nodes, but the clinical significance, including prognosis and therapeutic approach is yet unclear, even more with capsular extravasation. IMLN metastases are strongly correlated with axillary lymph nodes involvement and therefore a guide for further surgical management of the axillary nodes.

关键词： Breast cancer sentinel lymph node lymph node dissection metastasis locoregional neoplasm recurrence

Diagnosis of Laron syndrome using monoplex-polymerase chain reaction technology with a whole-genome amplification template: A case report

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World Journal of Clinical Cases 2019年第23期7卷 4029-4035页

作者： Adina Neumann Miguel Angel alcantara-Ortigoza Ariadna Gonzalez-del Angel Felipe Camargo-Diaz Esther Lopez-Bayghen Laboratorio de Investigacion y Diagnostico Molecular Instituto de Infertilidad y Genetica Mexico SCINGENESMexico City 05320Mexico Instituto Nacional de Pediatria Torre de InvestigacionMexico City 04530Mexico Laboratorio de Biologia Molecular Departamento de Genetica HumanaInstituto Nacional de PediatriaMexico City 04530Mexico Departamento de Toxicologia Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional(CINVESTAV-IPN)Mexico City 07360Mexico

BACKGROUND Laron syndrome(LS)is an autosomal recessive hereditary condition affecting only 1/1000000 *** cause is associated with mutations in the growth hormone(GH)receptor(GHR),leading to GH *** patients typically present with severe growth retardation,obesity,and abnormal sexual ***,LS diagnosis is performed ***,we assessed the efficiency of Pre-implantation Genetic Testing(PGT)coupled with monoplex-polymerase chain reaction(PCR)technology for detecting this monogenic disease in embryos from a couple confirmed as LS heterozygous carriers CASE SUMMARY The couple LS-carriers were confirmed by the presence of a first child born with *** couple underwent a standard in vitro fertilization(IVF)*** was collected from trophectoderm cells from day 5 *** genome amplification(WGA)was performed using a Sureplex DNA Amplification System and analyzed by PCR,targeting the deletion of the exons 5 and 6 in the GHR gene as well as PGT by Next-generation Sequencing(Illumina).Eleven embryos were collected and analyzed.27.3%were the wild type for GHR,45.5%were heterozygotes,and 18.2%homozygous *** embryo yielded no *** 2-embryos transfers were performed;2 normal homozygous and four heterozygous carriers were selected for *** first two transfers were unsuccessful,whereas the final transfer with two heterozygous embryos resulted in clinical *** genomic composition of the fetus was verified,applying the same techniques using amniocytes,extracted after 21 wk of the ongoing *** fetus was confirmed as GHR deletion in exon 5-6,carrier.A non-affected baby was *** Here,we present a case demonstrating that using WGA as a template in addition to PCR targeting specific gene regions,exons 5 and 6 on the GHR gene,could identify LS carrier *** provides evidence that WGA and PCR serve as an excellent tool to detect this specific monogenic disease in IVF e

关键词： Growth hormone insensitivity Growth hormone receptor mutations Intragenic deletions Molecular diagnosis Embryo diagnosis Laron syndrome Case report

The Tesistan, Mexico earthquake (M_w 4.9) of 11 May 2016: seismic-tectonic environment and resonance vulnerability on buildings

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Earthquake Engineering and Engineering Vibration 2019年第3期18卷 579-595页

作者： Alejandro Ramírez-Gaytán Adolfo Preciado William L. Bandy Edilson F. Salazar-Monroy Miguel A. Jaimes Leonardo alcantara Departamento de Ciencias Computacionales Centro Universitario de Ciencias Exactas e Ingeniería Universidad de Guadalajara Boulevard Marcelino García Barragán # 1421 44430 Guadalajara Jalisco México Departamento del Hábitat y Desarrollo Urbano Instituto Tecnológico y de Estudios Superiores de Occidente (ITESO). Periférico Sur Manuel Gómez Morin 8585 45604 Tlaquepaque Jalisco México Instituto de Geofísica Universidad Nacional Autónoma de México Circuito Interior Ciudad Universitaria Del. Coyoacán 04510 México Programa de Posgrado en Ciencias de la Tierra Universidad Nacional Autó noma de Mé xico Circuito Interior Ciudad Universitaria Del. Coyoacá n 04510 Mé xico Instituto de Ingenieria Universidad Nacional Autónoma de México Circuito Interior Ciudad Universitaria Del. Coyoacán 04510 México

To highlight the importance of small earthquakes in seismic hazard, a study of the 11 May 2016, Mw 4.9, Tesistan, Mexico earthquake is presented. Due to the close proximity of the event to the city, accelerations were considerably higher than those caused by historical severe earthquakes (6.0 < Mw < 8.2). This paper addresses two objectives related to the Tesistan event: the fi rst is to estimate the focal mechanism solution in order to place the event in the context of the tectonic environment of this area. The second is focused on a vulnerability evaluation of buildings that suff ered resonance. Several building′s typologies with variations in construction system and height are assessed in terms of resonance with the structural and soil periods. The results show that around the Zapopan station, strong damage is expected in intermediate to high-rise buildings (12-30 m) with moment resistant frame systems and in reinforced concrete shear walls. Masonry structures around this station may not present resonance. In contrast, in the surroundings of the Guadalajara station, all intermediate height buildings from 9 to 21 m may present resonance.

关键词： Tesistan earthquake seismicity of Guadalajara site eff ects structural vulnerability

SCO and Cybersecurity:Eastern Security Vision for Cyberspace

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International Relations and Diplomacy 2018年第10期6卷 549-555页

作者： Bruna Toso de alcantara Federal University of Rio Grande do Sul Rio Grande do SulBrazil

Cyberspace is presenting not only new challenges for states but also new opportunities for power ***,analyzing how non-Western perspectives have been developed around this subject becomes relevant to understand some dynamics of contemporary international *** this way,in order to understand how China and Russia have been behaving in this area,the present paper seeks,through a constructivist approach based on the perspective of the regional complexes,to develop an exploratory research toward the existence of an Eastern regional strategic thinking to cybersecurity,materialized by the Shanghai Cooperation Organization(SCO).To achieve this objective,the paper will use the qualitative document analysis as a method,seeking not only to verify if such Eastern thought for cyberspace is cohesive within the organization,but also to explain what the implications for international society of this thought are.

关键词： Cyberspace SCO Security

Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?

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World Journal of Gastroenterology 2014年第18期20卷 5235-5243页

作者： Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M alcantara-Neves Instituto de Ciências da Saúde Universidade Federal da BahiaSalvadorBahia 41110-100Brazil

Helicobacter pylori(***)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human *** is a risk factor for gastritis,ulcer disease and stomach *** against *** is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including ***,host genetic factors that affect cytokines may determine differences in the susceptibility to many *** this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to *** and discuss how such polymorphisms may influence infection/disease outcomes.

关键词： Helicobacter pylori Stomach cancer Immunity Cytokines Polymorphisms

Transanal endoscopic surgery in rectal cancer

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World Journal of Gastroenterology 2014年第33期20卷 11538-11545页

作者： Xavier Serra-Aracil Laura Mora-Lopez Manel alcantara-Moral Aleidis Caro-Tarrago Carlos Javier Gomez-Diaz Salvador Navarro-Soto Coloproctology Unit General and Digestive Surgery Service Parc Tauli University Hospital Universitat Autònoma de Barcelona 08208 Sabadell (Barcelona) Spain

Total mesorectal excision(TME) is the standard treatment for rectal cancer, but complications are frequent and rates of morbidity, mortality and genitourinary alterations are high. Transanal endoscopic microsurgery(TEM) allows preservation of the anal sphincters and, via its vision system through a rectoscope, allows access to rectal tumors located as far as 20 cm from the anal verge. The capacity of local surgery to cure rectal cancer depends on the risk of lymph node invasion. This means that correct preoperative staging of the rectal tumor is necessary. Currently, local surgery is indicated for rectal adenomas and adenocarcinomas invading the submucosa, but not beyond(T1). Here we describe the standard technique for TEM, the different types of equipment used, and the technical limitations of this approach. TEM to remove rectal adenoma should be performed in the same way as if the lesion were an adenocarcinoma, due to the high percentageof infiltrating adenocarcinomas in these lesions. In spite of the generally good results with T1, some authors have published surprisingly high recurrence rates; this is due to the existence of two types of lesions, tumors with good and poor prognosis, divided according to histological and surgical factors. The standard treatment for rectal adenocarcinoma T2N0M0 is TME without adjuvant therapy. In this type of adenocarcinoma, local surgery obtains the best results when complete pathological response has been achieved with previous chemoradiotherapy. The results with chemoradiotherapy and TEM are encouraging, but the scientific evidence remains limited at present.

关键词： Rectal cancer Rectal adenocarcinoma Transanal endoscopic microsurgery Transanal endo-scopic surgery Colorectal cancer