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Prevalence and risk factors of fatty liver disease in Chengdu,Southwest China

Hepatobiliary & Pancreatic Diseases International 2009年第4期8卷 377-382页

作者： Li, Hong Wang, You-Juan Tan, Ke Zeng, Li Liu, Li Liu, Feng-Jun Zhou, Tao-You Chen, en-qiang Tang, Hong Sichuan Univ W China Hosp Natl Key Lab Biotherapy Div Mol Biol Infect DisCtr Infect Dis Chengdu 610041 Peoples R China W China Hosp Phys Examinat Ctr Chengdu 610041 Peoples R China Sichuan Univ Dept Hlth Stat W China Coll Publ Hlth Chengdu 610041 Peoples R China

BACKGROUND: Fatty liver disease (FLD) is increasingly recognized as one of the most common chronic liver diseases in China. This study aimed to investigate the prevalence and risk factors of FLD in Chengdu, Southwest China, and to provide a relevant basis for the prevention and intervention of FLD. METHODS: Altogether 9094 subjects (4721 men and 4373 women) of over 18 years old who had received a medical checkup in the West China Hospital of Sichuan University between January and December 2007 were evaluated for FLD. FLD was diagnosed by ultrasonography. Body mass index (BMI), height, body weight, blood pressure, fasting plasma glucose (FPG), triglycerides (TG), total cholesterol (TCh), alanine aminotransferase (ALT), hepatitis B surface antigen (HBsAg), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured using routine laboratory methods. RESULTS: The overall prevalence of FLD was 12.5%, which was more than 3-fold higher in males than in females 2 (18.9% vs. 5.7%, chi(2) =359.624, Pence increased with age in females and males of less than 50 years. The prevalence of alcoholic, suspected alcoholic, and non-alcoholic FLD was 2.6%, 3.6%, and 6.3%, respectively. Multiple logistic regression analyses showed that 10 factors (male sex, age, BMI, FPG, hypertension, TG, TCh, HDL-C, LDL-C, and ALT abnormalities) were closely related to FLD. In heavy drinkers, obesity increased the risk of FLD by 23.78-fold (95% CI, 10.22-55.33), but heavy drinking was only associated with a 2-fold (95% CI, 1.50-2.66) increased risk in obese subjects. CONCLUSIONS: The prevalence of FLD among a health-checkup population in Chengdu, Southwest China was lower than the published for other areas of China. FLD in Chengdu adults was found to be closely associated with sex, age, BMI, and other metabolic syndrome features.

关键词： fatty liver prevalence risk factors obesity alcohols

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Replanting Affects the Tree Growth and Fruit Quality of Gala Apple

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Journal of Integrative Agriculture 2014年第8期13卷 1699-1706页

作者： LIU en-tai WANG Gong-shuai LI Yuan-yuan SHen Xiang CHen Xue-sen SONG Fu-hai WU Shu-jing CHen qiang MAO Zhi-quan College of Horticultural Science and engineering/State Key Laboratory of Crop Biology Shandong Agricultural University Qingdao Bright Moon Bluesea Bio-Tech Co Ltd. Faculty of Landscape Architecture College of Art Shandong Jianzhu University

Apple replant disease（ARD） causes the inhibition of root system development, stunts tree growth and so on. To further investigate the effects of ARD on apple fruits, a 25-year-old apple orchard was remediated to establish a replant orchard between November 2008 and March 2009. A rotational cropping orchard was established on an adjacent wheat field. The cultivar and rootstock-scion combination used in the newly established orchards was Royal Gala/M26/Malus hupehensis Rehd. Ripe fruits were collected in mid-August 2011 and mid-August 2012, meanwhile, the following indices were measured： yield per plant; fruit weight; the fruit shape index; the contents of anthocyanin, carotenoid and chlorophyll; the soluble sugar content in the flesh; titratable acid; the sugar-acid ratio; firmness; and aroma components; apple plant ground diameter, plant height increment and the total length of the current-year shoots. The results showed that compared to rotational cropping, continuous cropping yielded statistically significant reductions in fruit weight and yield per plant of 39.8 and 76.5%, respectively. However, there were no changes in the fruit shape index. The anthocyanin and carotenoid contents decreased by 81.7 and 37.7%, respectively, while the chlorophyll content increased by 251.0%. All of these differences in content were statistically significant. The soluble sugar levels and sugar-acid ratio decreased by 25.4 and 60.9%, respectively, but the titratable acid levels and fruit firmness increased by 90.9 and 42.8%, respectively. Ten of the most important esters contributing to the apple aroma were analyzed, and the following changes were observed： hexyl acetate, butyl acetate, hexyl butyrate, acetate-2-methyl butyl, 2-methyl-hexyl butyrate, amyl acetate, butyl butyrate, 2-methyl-butyl butyrate, hexyl propionate and hexyl hexanoate decreased by 25.5, 78.4, 89.1, 55.5, 79.5, 77.2, 86.8, 69.9, 61.2, and 68.1%, respectively. The contents of three other aroma components,（E）-2-h

关键词： apple fruit replanting quality yield

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Rapid Differentiation of Aconiti Kusnezoffii Radix from Different Geographic Origins Using Ultra-Performance Liquid Chromatography Coupled with Time-of-Flight Mass Spectrometry

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World Journal of Traditional Chinese Medicine 2021年第1期7卷 71-77页

作者： en-Yu Lu Zi-Feng Pi Zhong Zheng Shu Liu Feng-Rui Song Na Li Zhi-qiang Liu National Center for Mass Spectrometry in Changchun Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass SpectrometryChangchun Institute of Applied ChemistryChinese Academy of ScienceChangchunChina College of Applied Chemistry and engineering University of Science and Technology of ChinaHefeiChina Changchun Sunnytech Co. Ltd.ChangchunChina State Key Laboratory for Quality Research of Chinese Medicines Macao University of Science and TechnologyTaipaMacao

Objective:There are different geographic origins of Aconiti Kusnezoffii Radixs(AKRs)sold in the market with different *** study aims to establish a rapid analysis method to distinguish the different geographic origins of AKRs and to realize the rapid evaluation of their ***:An ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry(UPLC-Q-TOF MS)method was utilized to acquire the constituents'information of AKRs from different geographic *** data and Progenesis QI software were employed to identify the chemical *** component analysis(PCA)was applied to comparing MS data to find the chemical markers of AKRs from different geographic ***:Twenty-three components were detected and 17 out of them were identified,including diester-diterpenoid alkaloids,monoester-diterpenoid alkaloids,and amine-diterpenoid *** pairs of isomers were detected and two of them were distinguished by the retention time of standard *** chemical markers were screened out through PCA and orthogonal partial least square discriminant *** detecting Napelline or isomer of Napelline(m/z 360.2530)and Aconifine(m/z 662.3170),AKRs from inner Mongolia autonomous could be *** to the existence of benzoylaconine(m/z 604.3108)and Indaconitine(m/z 630.3159),it could be confirmed that the AKRs are from Xinjiang Uygur *** that cannot detect compounds above-mentioned could be from Liaoning or Shanxi ***:The chemical profile could be used not only to distinguish the AKRs from different geographic origins but also to identify the true and false of *** study lays a foundation for the study of efficacy and toxic of AKRs.

关键词： Aconiti Kusnezoffii Radix chemical markers rapid differentiation ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry

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Analysis of gain distribution in cladding-pumped thulium-doped fiber laser and optical feedback inhibition problem in fiber-bulk laser system

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Chinese Physics B 2015年第10期24卷 238-247页

作者：吉恩才柳强胡震岳巩马理 State Key Laboratory of Precision Measurement Technology and Instruments Center for Photonics and ElectronicsDepartment of Precision InstrumentTsinghua University

The steady-state gain distribution in cladding pumped thulium-doped fiber laser（TDFL） is analytically and numerically solved based on the rate equations including loss coefficients and cross relaxation effect. With the gain curve, a problem, which is named optical feedback inhibition（OFI） and always occurs in tandem TDFL-Ho：YAG laser system, is analyzed quantitatively. The actual characteristics of output spectra and power basically prove the conclusion of theoretical analysis. Then a simple mirror-deflected L-shaped cavity is employed to restrain the external feedback and simplify the structure of fiber-bulk Ho：YAG laser. Finally, 25 W of 2097-nm laser power and 51.2% of optical-to-optical conversion efficiency are obtained, and the beam quality factor is less than 1.43 obtained by knife-edge method.

关键词： thulium-doped fiber laser gain distribution optical feedback inhibition Ho:YAG laser

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Quantum　Chemistry　Studies　on　the　Heteropoly　Blues　of　Molybdosilic　Series　with　α-Keggin　Structure

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Chemical Research in Chinese Universities 1997年第3期13卷 262-267页

作者： FU qiang, YANG Ming , CHen Bin , WANC en-Bo, XIE De-Min , JIANG Zhong-Ming,PenG Jun (Department of Chemistry,Northeast Normal University,Changchun,130024) NE NORMAL UNIV DEPT CHEMCHANGCHUN 130024PEOPLES R CHINA

SCC-DV-X method was used for the theoretical calculation of heteropoly an- ion , [SiMoO40]4- . and heteropoly blue anions,[SiMo2 Mo10O40]6 and [SiMo4 Mo!; O' 1,-. Th. ***.. .ol...l.. orbital. , orbital ***.. , *** 1...l. , the o.- cupied numbers of basis functions , free valences , Mulliken populations and the fig- ure of the total density of states have been obtained. The theoretical analysis indi- cates that all the atoms in the anions participate in chemical reactions , but Oc and Od have higher chemical activities than other atonts , which is supported by the ex- perimental results. The heteropoly hue anions with the α-Keggin structure distort a little and the levels of valence orbitals demonstrate that [SiMo4 Mo8O40]8 can form a six-electron heteropoly blue anoint by accepting two electrons.

关键词： SCC-DV-X method α-Keggin structure Fermi level Mulliken popu- lations

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三角形对称双脊波导的有限元分析与设计

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通信学报 2011年第8期32卷 31-37页

作者：陈小强任恩恩逯迈王磊兰州交通大学自动化与电气工程学院甘肃兰州730070 兰州交通大学光电技术与智能控制教育部重点实验室甘肃兰州730070

在对新型三角形对称双脊波导特性参数研究的基础上,应用有限元法系统分析计算了三角形对称双脊波导几何尺寸变化对截止波长、单模带宽、场结构、特性阻抗、衰减常数及功率容量等传输特性的影响。与常规矩形双脊波导相比,三角形对称双脊... 详细信息

在对新型三角形对称双脊波导特性参数研究的基础上,应用有限元法系统分析计算了三角形对称双脊波导几何尺寸变化对截止波长、单模带宽、场结构、特性阻抗、衰减常数及功率容量等传输特性的影响。与常规矩形双脊波导相比,三角形对称双脊波导具有小的截止波长、窄的单模带宽、低的功率容量、高的衰减常数和大的特性阻抗,可用于窄带微波滤波器。得到的数据结论将为三角形脊波导在微波系统中的设计应用提供详细的设计数据。

关键词：三角形脊波导有限元法截止波长特性阻抗衰减特性功率容量

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Antibacterial activities of a novel Cu-bearing high-entropy alloy against multi-drug-resistant Acinetobacter baumannii and Staphylococcus aureus

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Rare Metals 2022年第2期41卷 570-579页

作者： en-Ze Zhou Guang-Yu Ren Yun-Ling Sun Yong-qiang Fan Yi Yang Ming-Yue Sun Da-Ke Xu Yi-Ping Lu Jian-Jun Wang Hua-Bing Li Fu-Hui Wang Shenyang National Laboratory for Materials Science Key Laboratory for Anisotrotropy and Texture of Materials(Ministry of Education)School of Materials Science and EngineeringNortheastern UniversityShenyang 110819China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China General Hospital of Northern Theater Command Shenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China

Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus(MRSA)are two prevalent pathogens and have developed high resistant to most ***,it is a pressing need to develop a new method to inhibit the spread of drug-resistant *** containing high-entropy alloy(HEA,Al0.4CoCr-CuFeni)is a new kind of alloy material,which shows extensive antibacterial activity and mechanical properties in our previous *** study further develops another HEA(CoCrCuFeni)and evaluates its resistance against gram-negative *** and Gram-positive *** antibacterial tests show that the antibacterial rate of the HEA toward both bacteria reached nearly 99%,far better than the traditional copper-bearing 304 stainless steel(304 Cu-SS).The biofilm observation shows that the HEA could not only kill the planktonic bacteria,but also effectively inhibit the formation of *** data demonstrate that CoCrCuFeni HEA possesses effective antibacterial and antibiofilm activities,making it a potential candidate for using in hospital,food industry,and domestic kitchens.

关键词： High-entropy alloy Acinetobacter baumannii Methicillin-resistant Staphylococcus aureus(MRSA) Antibacterial activity Antibiofilm activity

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Diagnosis of gastric intraepithelial neoplasia by narrow-band imaging and confocal laser endomicroscopy

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World Journal of Gastroenterology 2012年第34期18卷 4771-4780页

作者： Shu-Fang Wang Yun-Sheng Yang Li-Xin Wei Zhong-Sheng Lu Ming-Zhou Guo Jin Huang Li-Hua Peng Gang Sun en-qiang Ling-Hu Jiang-Yun Meng Departments of Gastroenterology and Hepatology Chinese PLA General Hospital Beijing 100853 China Departments of Pathology Chinese PLA GeneralHospital Beijing 100853 China

AIM:To evaluate the diagnosis of different differentiated gastric intraepithelial neoplasia (IN) by magnifica-tion endoscopy combined with narrow-band imaging (ME-NBI) and confocal laser endomicroscopy (CLE). METHODS:Eligible patients with suspected gastric IN lesions previously diagnosed by endoscopy in secondary hospitals and scheduled for further diagnosis and tratment were recruited for this study. Excluded from the study were patients who had liver cirrhosis, impaired renal function, acute gastrointestinal (GI) bleeding, coagulopathy, esophageal varices, jaundice, and GI post-surgery. Also excluded were those who were pregnant, breastfeeding, were younger than 18 years old, or were unable to provide informed consent. All patients had all mucus and bile cleared from their stom-achs. They then received upper GI endoscopy. When a mucosal lesion is found during observation with whitelight imaging, the lesion is visualized using maximal magnification, employing gradual movement of the tip of the endoscope to bring the image into focus. Saved images are analyzed. Confocal images were evaluated by two endoscopists (Huang J and Li MY), who were familiar with CLE, blinded to the related information about the lesions, and asked to classify each lesion as either a low grade dysplasia (LGD) or high grade dysplasia (HGD) according to given criteria. The results were compared with the final histopathologic diagnosis. ME-NBI images were evaluated by two endoscopists (Lu ZS and Ling-Hu EQ) who were familiar with NBI, blinded to the related information about the lesions and CLE images, and were asked to classify each lesion as a LGD or HGD according to the "microvascular pattern and surface pattern" classification system. The results were compared with the final histopathologic diagnosis. RESULTS: The study included 32 pathology-proven low grade gastric IN and 26 pathology-proven high grade gastric IN that were detected with any of the modalities. CLE and ME-NBI enabled clear v

关键词： Gastric intraepithelial neoplasia Histologicaldiagnosis Confocal laser endomicroscopy Magnifica-tion endoscopy Narrow-band imaging Gastric intraepi-thelial neoplasia lesion

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食管胃底静脉曲张致上消化道出血的内镜下诊治

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继续医学教育 2007年第3期21卷 18-20页

作者：令狐恩强中国人民解放军总医院消化科北京100853

肝硬化是我国的常见病，无食管胃底曲张静脉的肝硬化患者，每年有5％～15％出现曲张静脉，曲张静脉一旦形成，每年增粗约4％～10％，最终所有的肝硬化患者都会出现食管胃底静脉曲张。约1／3的食管胃底曲张静脉患者出现曲张静脉破裂出血... 详细信息

肝硬化是我国的常见病，无食管胃底曲张静脉的肝硬化患者，每年有5％～15％出现曲张静脉，曲张静脉一旦形成，每年增粗约4％～10％，最终所有的肝硬化患者都会出现食管胃底静脉曲张。约1／3的食管胃底曲张静脉患者出现曲张静脉破裂出血，每次出血的病死率达20％～30％，未经治疗的患者一年内因出血致死的机率可达70％。首次出血后6周之内会发生再次出血，48小时之内是再次出血的高峰时间。内镜下进行食管静脉曲张的硬化剂注射治疗（EIS）、内镜下食管静脉曲张套扎治疗（EVL）、组织粘合剂注射治疗以及联合治疗方法的出现，使我们有能力救治曲张静脉破裂出血患者。

关键词：食管胃底静脉曲张上消化道出血食管胃底曲张静脉内镜曲张静脉破裂出血硬化剂注射治疗食管静脉曲张肝硬化患者

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Tungsten-containing high-entropy alloys: a focused review of manufacturing routes, phase selection, mechanical properties, and irradiation resistance properties

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Tungsten 2021年第2期3卷 181-196页

作者： Tian-Xin Li Jun-Wei Miao en-Yu Guo He Huang Jun Wang Yi-Ping Lu Tong-Min Wang Zhi-qiang Cao Ting-Ju Li Key Laboratory of Solidifi cation Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Materials China Academy of Engineering PhysicsMianyang 621907China State Key Laboratory of Solidifi cation Processing Northwestern Polytechnical UniversityXi’an 710072China High entropy Alloy Materials engineering Research Center(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China

Alloying is one of the most effective means to confer superior properties to metal *** far too long,conventional W-based alloys were generally improved by the addition of minor *** exploitation of conventional W-based alloy is restricted to the corner of multielement phase diagrams with tiny compositional ***-entropy alloys(HEAs)are a novel kind of alloys consisting of multi-principal alloying elements(usually more than 4)and have attracted increasing attention,since they were first reported in *** emergence of HEAs filled the gap of the unexplored central region of multielement phase *** them,tungsten-containing HEAs(TCHEAs)exhibit excellent mechanical properties,especially at extraordinarily elevated ***,recent studies showed that TCHEAs had outstanding irradiation resistance *** might serve as a promising candidate for plasma-facing materials in the fusion *** characteristics of TCHEAs are different from other HEAs due to the addition of tungsten with ultrahigh-melting ***,this paper aimed to introduce the manufacturing routes of TCHEAs;review the phase selection,mechanical properties,and irradiation resistance properties of TCHEAs;and propose the future prospects of TCHEAs.

关键词： Tungsten-containing high-entropy alloys Irradiation resistance properties Mechanical properties Manufacturing routes Phase selection

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