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Exercise-induced torsades de pointes as an unusual presentation of cardiac sarcoidosis: A case report and review of literature

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World Journal of Cardiology 2020年第6期12卷 291-302页

作者： Chadi Ghafari Frédéric Vandergheynst emmanuel parent Kaoru Tanaka Stéphane Carlier Department of Cardiology Centre Hospitalier Universitaire Ambroise ParéMons 7000Belgium Department of Cardiology Universitéde MonsMons 7000Belgium Department of Internal Medicine Cliniques Universitaires de Bruxelles-ErasmeBruxelles 1070Belgium Department of Cardiology Universitair Ziekenhuis BrusselsJette 1090Belgium

BACKGROUND Sarcoidosis is a rare multisystem disease characterized histologically by noncaseating granuloma formation in the affected *** cardiac sarcoidosis is found on autopsy in up to 25%of sarcoidosis cases,it is still underdiagnosed and is associated with a poor *** the etiology of sarcoidosis remains unclear,an antigen triggered exaggerated immune response has been *** detection and prompt management of cardiac sarcoidosis remains *** SUMMARY A 60-year-old female,with pulmonary sarcoidosis in remission,presented to the cardiology outpatient clinic for evaluation of weeks-long dyspnea on moderate exertion(New York Heart Association class II)that was relieved by *** exercise stress test showed multifocal ventricular extrasystoles,followed by a self-limiting torsades de *** magnetic resonance imaging showed nondilated and normotrophic left ventricle with basoseptal and mid-septal *** magnetic resonance imaging-derived left ventricular ejection fraction was 45%.Delayed enhancement showed patchy transmural fibrosis of the septum and hyperenhancement of the papillary muscles,all in favor of extensive cardiac involvement of sarcoidosis.A double-chamber implantable cardiac defibrillator was implanted,and methylprednisolone(12 mg/d)and methotrexate(12.5 mg/wk)treatment was ***-up and implantable cardiac defibrillator interrogation showed episodes of asymptomatic nonsustained ventricular tachycardia and an asymptomatic episode of nonsustained ventricular tachycardia ending by the first antitachycardia pacing *** Along an extensive review of the literature,this unusual case report highlights the importance of early detection of cardiac involvement of sarcoidosis,in order to avoid potential complications and increase survival.

关键词： Sarcoidosis Cardiac sarcoidosis Torsades de pointes Ventricular tachycardia Immunotherapy Case report

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Potential of using forest residue to offset coal use in co-fired coal power plants in the eastern United States

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International Journal of Agricultural and Biological Engineering 2014年第4期7卷 99-105页

作者： Jason parent Marcello Graziano Xiusheng Yang Department of Natural Resources and the Environment University of ConnecticutStorrsCT 06269-4087USA Department of Geography University of ConnecticutStorrsCT 06269-1063USA

The global transition from fossil fuel-based energy sources to renewable energy sources will be most effective,for at least the near future,by utilizing local resources and existing *** many areas of the eastern United States,forest residue is abundant and can be used in existing facilities to supplement coal in coal-fired power *** forest residue has potential as a renewable energy source that could be effectively utilized in the near *** study uses GIS to estimate the potential quantity of forest residue available for use in coal-fired power plants in the eastern United *** costs limit the distance over which it is feasible to transport forest residue to the power plants and these costs may fluctuate depending on economic ***,we consider three scenarios in our analysis assuming the maximum feasible transport distances to be 60,80,and 100 *** the eastern U.S.,the total annual forest residue available to coal plants is approximately 29.4,40.2,and 48.2 million dry tons,respectively,for maximum transport distances of 60,80,and 100 *** an 80 km transport distance,forest residue has the potential to reduce coal consumption by 22.3 million tons per *** this scenario,greenhouse gas emissions would be reduced by almost 58.1 million tons per year,and NOx and SOx emissions would be reduced by 69.3 and 122.6 thousand tons *** analysis suggests that by offsetting coal use,forest residue has the potential to substantially reduce power plant emissions.

关键词： forest residue coal biofuel co-firing GIS alternative energy

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The History of the Basal Ganglia: The Contribution of Karl Friedrich Burdach

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Neuroscience & Medicine 2012年第4期3卷 374-379页

作者： André parent Département de Psychiatrie et de Neurosciences Faculté de Medicine Université Laval Québec (Québec) Canada.

It took many centuries for the basal ganglia (BG) to be recognized as specific brain entities involved in the control of psychomotor behavior. Andreas Vesalius (1514-1564) was the first to delineate this set of structures, but he did not name them nor payany attention to their functional significance. This was left to the English physician Thomas Willis (1621-1675), who used the term corpus striatum (striated or chamfered body) to designate the largest BG constituent, which he considered a major sensorimotor integration center. Willis’s pioneering description influenced markedly some 18th and 19th centuries scholars, particularly the German physician and anatomist Karl Friedrich Burdach (1776-1847). Burdach’s insightful studies of the human brain are summarized in a three-volume treatise entitled Vom Baue und Leben des Gehirns (1819-1826). This landmark opus provides a description of the BGwhose originality has largely been overlooked. Burdach’s careful investigation allowed him to differentiate the caudate nucleus from the putamen, which he respectively termed Streifenhügel (elongated hillock) and Schale (shell). He also called the putamen Linsenkern (lens-shaped nucleus), a term that he admittedly borrowed from his compatriot Johann Christian Reil (1759-1813). He further identified a paler structure (blasser Klumpen) within the inner portion of the lentiform nucleus that he called globus pallidus, and correctly identified its inner and outer segments (innern und ?ussern Theil). He aptly pointed out that the major BG nuclei are separated from one another by fibers fascicles that he termed inner and ?ussre Capsel (internal and external capsules). Burdach also referred to the substantia nigra (schwarzgraue Schicht or stratum nigrum) and claustrum (Vormauer), but gave full credit to the French anatomist Félix Vicq-d’Azyr (1748-1794) for their discovery. Although Burdach did not comment much on BG function, his anatomical description was sufficiently cogent to be still

关键词： Basal Ganglia Movement Disorders Striatum Globus Pallidus Putamen Neuroscience History

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Louis Pierre Gratiolet (1815-1865) and His Contribution to the Study of Cerebral Convolutions in Primates

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Neuroscience & Medicine 2014年第1期5卷 1-8页

作者： André parent Département de Psychiatrie et de Neurosciences Faculté de Médecine Université Laval Québec City Canada

Louis Pierre Gratiolet (1815-1865) was one of the first modern anatomists to pay attention to cerebral convolutions. Born in Sainte-Foy-la-Grande (Gironde), he moved to Paris in 1834 to study medicine, as well as comparative anatomy under Henri de Blainville (1777-1850). In 1842, he accepted de Blainville’s offer to become his assistant at the Muséum d’histoire naturelle and progressively abandoned medicine for comparative anatomy. He undertook a detailed study of brains of human and nonhuman primates and soon realized that the organizational pattern of cerebral convolutions was so predictable that it could serve as a criterion to classify primate groups. He noted that only the deepest sulci exist in lower primate forms, while the complexity of cortical folding increases markedly in great apes and humans. Gratiolet provided the first cogent description of the lobular organization of primate cerebral hemispheres. He saw the insula as a central lobe around which revolved the frontal, parietal, temporal (temporo-sphenoidal) and occipital lobes. He correctly identified most gyri and sulci on all brain surfaces, introduced the term “plis de passage” for some interconnecting gyri, and provided the first description of the optic radiations. In the early 1860s, Gratiolet fought a highly publicized battle against Paul Broca (1824-1880) on the relationship between brain and intelligence. Gratiolet agreed that the brain was most likely the seat of intelligence, but he considered human cognition far too subtle to have any direct relationship with brain size. He argued that a detailed study of the human brain architecture would be more profitable than Broca’s vain speculations on the relationship between brain weight and intelligence, which he considered a monolithic entity. Despite remarkable scientific achievements and a unique teaching capacity, Gratiolet was unable to secure any academic position until three years before his sudden death in Paris at age 49.

关键词： Humans Primates Cerebral Hemispheres Cerebral Convolutions Cerebral Cortex Neuroscience History

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Biochemical Fractionation of Soil Organic Matter after Incorporation of Organic Residues

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Open Journal of Soil Science 2015年第6期5卷 135-143页

作者： Serge-étienne parent Léon E. parent Department of Soils and Agrifood Engineering Université Laval Québec Canada

Soil organic matter (SOM) is a key factor for building and maintaining soil quality. The SOM quality is commonly assessed using densitometric and sieving separation methods, but such methods do not inform on the biochemical composition of SOM. Our objective was to evaluate the van Soest extraction procedure for soluble (SOL), holocellulose (HOLO) and lignin/cutin (LIC) fractions of SOM after incorporating crop residues and animal wastes into a C-depleted loamy sand. Millet cuttings, oat straw, fresh cattle manure and cattle manure compost were dried, sieved to obtain 53 - 250 and 250 - 2000 μm size fractions and characterized biochemically using a modified NDF-ADF-ADL van Soest method. Soil was also sieved into 53 - 250 and 250 - 2000 μm fractions. On a dry mass basis, crop residues contained 60% - 70% holocellulose while animal wastes contained more than 40% ash. Each soil fraction was combined with three rates of the corresponding organic fraction (2, 4, and 6 Mg·haǃ millet forage cuttings or oat straw and 5, 10, and 15 Mg·haǃ of cattle manure or cattle manure compost). Changes in soil biochemical components were analyzed using the balance method of compositional data analysis. Amendment, application rate and size fraction influenced significantly (p < 0.05) the [SOL | HOLO] balance but did not significantly affect the [SOL,HOLO | LIC] balance. The [SOL | HOLO] increased linearly with addition rate of crop residues, and decreased linearly with addition rate of animal wastes. This approach of balancing biochemical SOM components is a promising method to monitor the changes in SOM quality after the incorporation of organic residues and to elaborate beneficial practices for managing crop residues and animal wastes in agro-ecosystems.

关键词： Soil Organic Matter Van Soest Holocellulose Lignin Compositional Data Analysis

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HAVE LESS,BE MORE Five Easy Steps for Cleaning Out Your Wardrobe

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城市漫步（上海版、英文） 2017年第3期 30-31页

作者： Timothy parent 不详

Is it possible to have too many clothes?While there's no correct answer;I'd argue that having more clothes doesn't necessarily mean yoifll be happier or better *** fact,it may make it harder to find what you're looking for And I don't just mean asking your ayi where that one t-shirt *** having too many choices makes it difficult to maintain a cohesive sense of self.

关键词： looking dress And

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FASHION RULES NotAII Fashion Shows Are Created Equal

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城市漫步（上海版、英文） 2017年第5期 32-33页

作者： Timothy parent 不详

The idea of a'fashion show' is a rather loose *** are innumerable ways to present a new collection,so the fashion show itself has become another mode through which designers can communicate their vision and *** while most brands and platforms stick with the defaults,some designers are pushingthe boundaries of what a fashion show is and could be.

关键词： Create fashion communicate

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THE CREATION OF CREATIVITY Rounding Up Shanghai Fashion Week and Beijings Fashion Now

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城市漫步（上海版、英文） 2016年第11期 26-27页

作者： Timothy parent 不详

Timothy parent is the founder of *** and has followed Shanghai Fashion Week for 15 seasons and Fashion Now in *** he gives That san exclusive recap of which local fashion designers we should be looking out for.

关键词： Round looking fashion

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Short-Term Impact of Elemental Sulfur on Cranberry Nutrition and Crop Performance

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Open Journal of Soil Science 2023年第2期13卷 83-96页

作者： Reza Jamaly Serge-Étienne parent Noura Ziadi Léon E. parent Department of Soils and Agri-Food Engineering Université Laval Québec City Canada Ottawa Research and Development Centre Ottawa Canada Quebec Research and Development Centre Québec City Canada

Cranberry (Vaccinium macrocarpon Ait.) is an ammophilous plant grown on acid soils (pH 4.0 - 5.5). Elemental sulfur is commonly applied at a recommended rate of 1120 kg S ha−1 per pH unit to acidify cranberry soils, potentially impacting the plant mineral nutrition. The general recommendation may not fit all conditions encountered in the field. Our objective was to develop an equation to predict the sulfur requirement to reach pHwater of 4.2 to tackle nitrification in acidic cranberry soils varying in initial pH values, and to measure the effect of elemental sulfur on the mineral nutrition and the performance of cranberry crops. A 3-yr experiment was designed to test the effect of elemental sulfur on soil and tissue tests and on berry yield and quality. Four S treatments (0, 250, 500 and 1000 kg S ha−1) were established on three duplicated sites during two consecutive years. We ran soil, foliar tissue, berry tissue tests, and measured berry yield, size, anthocyanin content (TAcy), Brix, and firmness. Nutrients were expressed as centered log ratios to reflect nutrient interactions. Results were analyzed using a mixed model. Soil Ca decreased while soil Mn and S increased significantly (p ≤ 0.05). Sulfur showed no significant effects on nutrient balances in uprights. The S impacted negatively berry B balance, and positively berry Mn and S balances. A linear regression model relating pH change to S dosage and elapsed time (R2 = 0.53) showed that to reach pHwater of 4.2 two years after S application, 250 - 1000 kg S ha−1 could be applied depending on initial soil pH value. The stratification of surface-applied elemental S in the soil profile should be further examined in relation to plant rooting and nutrient leaching.

关键词： Sulfur Berry Yield and Quality Compositional Data Local Diagnosis Plant Nutrition Soil Acidification

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Fractal Kinetics Parameters Regulating Carbon Decomposition Rate under Contrasting Soil Management Systems

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Open Journal of Soil Science 2017年第7期7卷 111-117页

作者： Léon E. parent Department of Soils and Agrifood Engineering Université Laval Québec Canada

Agricultural soils can sequester and release large amounts of carbon. Accessibility of soil carbon to microbial attacks depends on biological, chemical, and physical protection mechanisms such as organic matter composition and particle size, soil aggregation, and chemical protection through the silt-clayorganic matter complex. While soil and organic matter are fractal objects controlling exposure of reactive surfaces to the environment, soil aggregation and biomass production and quality are regulated by agricultural practices. Organic matter decomposition in soil is generally described by the classical first-order kinetics equations fitted to define distinct carbon pools. By comparison, fractal kinetics assigns a coefficient to adjust time-dependent decomposition rate of total soil carbon to protection mechanisms. Our objective was to relate fractal parameters of organic matter decomposition to soil management systems. Retrieving published data, the decomposition of organic matter was modeled in a silt loam soil maintained under pasture, annual cropping or bare fallow during 11 years. The classical first-order kinetics model returned quadratic relationships indicating that reactive carbon decreased with time. Fractal kinetics rectified the relationships successfully. Initial decomposition rate (k 1 at t = 1) was 7 × 10-4 for pasture, 1 × 10-4 for annual cropping, and 0.5 × 10-4 for bare-soil fallow. Fractal coefficients h were 0.71, 0.45, and 0.25 for pasture, annual cropping and fallow, respectively. Due to aggregation, physical protection against microbial attacks was highest under pasture management, leading to higher carbon sequestration despite higher biomass production and “priming” effects. Parameters k 1 and h proved to be useful indicators for soil quality classification integrating the opposite effects of labile carbon decomposition and carbon protection mechanisms that regulate the decomposition rate of organic matter with time as driven by soil manageme

关键词： Aggregation Annual Cropping Carbon Pools Carbon Sequestration Fallow Fractal Coefficient Pasture Soil Quality

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