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Laparoscopic approach in complicated diverticular disease

World Journal of Gastrointestinal Surgery 2016年第4期8卷 308-314页

作者： Nicolás A Rotholtz Alejandro G Canelas Maximiliano E Bun Mariano Laporte emmanuel E Sadava Natalia Ferrentino Sebastián A Guckenheimer Department of Surgery Hospital Alemán Colorectal Surgery Division Hospital Alemán

AIM: To analyze the results of laparoscopic colectomy in complicated diverticular ***: This was a retrospective cohort study conducted at an academic teaching hospital. Data were collected from a database established earlier, which comprise of all patients who underwent laparoscopic colectomy for diverticular disease between 2000 and 2013. The series was divided into two groups that were compared: Patients with complicated disease(abscess, perforation, fistula, or stenosis)(G1) and patients undergoing surgery for recurrent diverticulitis(G2). Recurrent diverticulitis was defined as two or more episodes of diverticulitis regardless of patient age. Data regarding patient demographics, comorbidities, prior abdominal operations, history of acute diverticulitis, classification of acute diverticulitis at index admission and intra and postoperative variables were extracted. Univariate analysis was performed in both ***: Two hundred and sixty patients were included: 28%(72 patients) belonged to G1 and 72%(188 patients) to G2. The mean age was 57(27-89) years. The average number of episodes of diverticulitis before surgery was 2.1(r 0-10); 43 patients had no previous inflammatory pathology. There were significant differences between the two groups with respect to conversion rate and hospital stay(G1 18% vs G2 3.2%, P = 0.001; G1: 4.7 d vs G2 3.3 d, P < 0.001). The anastomotic dehiscence rate was 2.3%, with no statistical difference between the groups(G1 2.7% vs G2 2.1%, P = 0.5). There were no differences in demographic data(body mass index, American Society of Anesthesiology and previous abdominal surgery), operative time and intraoperative and postoperative complications between the groups. The mortality rate was 0.38%(1 patient), represented by a death secondary to septic shock in ***: The results support that the laparoscopic approach in any kind of complicated diverticular disease can be performed with low morbidity and acceptable conver

关键词： Complicated diverticulitis Laparoscopy Recurrent diverticulitis Sigmoid colectomy Outcomes

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Occupational exposure to flour dust among bakery workers:prevalence,potential hazards and promising interventions

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Toxicology Advances 2023年第4期5卷 33-44页

作者： Seyi-Samson Enitan Osareniro-Eguagie Osakue Esther-Ngozi Adejumo Temitope-Oyewole Olusanya emmanuel-Olusegun Ileoma Comfort-Bosede Enitan Nwachi-Idume Ogbonna Department of Medical Laboratory Science Babcock University Ilishan-RemoOgun state 121103Nigeria Department of Chemical Pathology Babcock University Teaching HospitalIlishan-RemoOgun state 121103Nigeria Department of Education Medical Laboratory Science Council of NigeriaFCT-Abuja 900110Nigeria

Occupational exposure to flour dust within bakery environments presents significant health hazards to bakery *** dust,generated as a byproduct during baking,becomes airborne during the baking process,thus constituting a respiratory *** health consequences include respiratory diseases,skin irritation,allergic reactions,and potential long-term health *** indicates that a broad segment of bakery workers encounters exposure to flour dust,with specific subgroups,such as bakers and dough mixers,being particularly *** factors to this exposure encompass insufficient ventilation and a lack of *** is vital to assess exposure levels through air quality monitoring and health *** interventions encompass engineering solutions(e.g.,ventilation systems,dust extraction),administrative measures(including training and the use of personal protective equipment),and the implementation of occupational health and safety *** efforts with healthcare professionals and regulatory authorities are paramount for achieving *** studies underscore the effectiveness of such interventions,resulting in improved worker health,thus underscoring the advantages of protective *** in this endeavor include industry resistance to change,financial considerations,and issues related to *** recommendations entail further research,policy enhancements,and the involvement of industry stakeholders and labor unions in advocating for worker safety.

关键词： flour dust bakery workers occupational exposure interventions health hazards

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“至上”与“虚无”

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现代装饰 2019年第1期 152-159页

作者： APPAREIL Atelier Quentin de Coster Rachel Griffin Jonas Lutz CTRLZAK Daisuke Kitagawa Elina Ulvio Amanda Karsberg Dennis Graben emmanuel Gonzalez Guzman Sanna V?lker Guilherme Wentz Laura Bilde Sara Moroni Axolight Valeria Vasileva Hi Thanks Bye 彭佳 Kristina Dam Studio

俄国画家马列维奇是'至上主义'抽象绘画流派的创始者,其绘画作品简约而纯粹,以最简单的形式——方块展现出艺术家丰富的感情世界,探索了形体、色彩与空间的关系。而同样善于运用几何形态的西班牙雕塑家奥泰萨的风格则显得冷静而克制,其... 详细信息

俄国画家马列维奇是'至上主义'抽象绘画流派的创始者,其绘画作品简约而纯粹,以最简单的形式——方块展现出艺术家丰富的感情世界,探索了形体、色彩与空间的关系。而同样善于运用几何形态的西班牙雕塑家奥泰萨的风格则显得冷静而克制,其雕塑作品通常看起来虚幻而抽象,没有强烈的情感表现,以高度理性化的手法展现出一种'虚无'的艺术境界。二人所专注的领域虽有不同,但他们的作品都在关注形式与其所在空间之间的复杂关系。

关键词：设计灵感衣帽架

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阿法达贝泊汀在2型糖尿病和慢性肾病中的疗效

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中国处方药 2009年第12期8卷 59-59页

作者： Marc A. Pfeffer emmanuel A. Burdmann Chao-Yin Chen

背景及目的：在2型糖尿病和慢性肾病患者中，贫血与心血管和肾脏事件风险增加有关。尽管阿法达贝泊汀（darbepoetin alfa）可有效增加血红蛋白水平，但它在临床上的疗效还未被充分验证，本研究就此进行了探讨。

关键词： 2型糖尿病慢性肾病疗效血红蛋白水平肾病患者心血管

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元情感结构作为成人与儿童互动素养的组成部分

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幼儿教育（教育科学） 2017年第10期 3-8页

作者：瓦西里奥斯·伊曼努埃尔·菲纳克思胡亿军张虹德国巴伐利亚学前教育研究所浙江外国语学院中德教育研究所浙江师范大学杭州幼儿师范学院《幼儿教育》编辑部

本研究从成人（父母、教师）对自己情感的意识、对儿童情感的意识和对儿童情感处理的支持等三个维度出发，将父母的元情感结构分为情感拒绝型和情感训练型两类。元情感结构对父母一儿童互动具有重大影响作用；幼儿园教师应该努力形成情... 详细信息

本研究从成人（父母、教师）对自己情感的意识、对儿童情感的意识和对儿童情感处理的支持等三个维度出发，将父母的元情感结构分为情感拒绝型和情感训练型两类。元情感结构对父母一儿童互动具有重大影响作用；幼儿园教师应该努力形成情感训练型元情感结构，运用合适的方法，支持儿童的情感处理，并通过优化自己的元情感结构去优化儿童的元情感结构。

关键词：元情感结构情感意识情感拒绝情感训练情感处理

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HLA-DQB1*0602基因与呼吸中枢低氧反应性降低有关

HLA-DQB1*0602基因与呼吸中枢低氧反应性降低有关

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中国睡眠研究会第六届学术年会

作者：高莹卉韩芳 emmanuel Mignot 魏翠英董霄松李静 Ling Lin 安培王慧玲王少杰何忠明李梅高占成 Kingman P.Strohl 北京大学人民医院呼吸与危重症医学科斯坦福大学发作性睡病中心凯斯西储大学呼吸与危重症医学及睡眠医学科

【目的】探索发作性睡病患者通气化学反应性的改变及其与下丘脑分泌素和HLA-DQB1*0602的关系。【方法】选择130名发作性睡病/下丘脑分泌素缺乏患者和117名年龄和性别匹配的正常对照。分别测定其HLA-DQB1*0602状态、低O高CO(△VE/△PCO,L... 详细信息

【目的】探索发作性睡病患者通气化学反应性的改变及其与下丘脑分泌素和HLA-DQB1*0602的关系。【方法】选择130名发作性睡病/下丘脑分泌素缺乏患者和117名年龄和性别匹配的正常对照。分别测定其HLA-DQB1*0602状态、低O高CO(△VE/△PCO,L/min/mmHg)反应性和低O(△VE/△SaO,L/min/%SaO)反应性。下丘脑分泌素缺乏的判定是通过检测脑脊液下丘脑分泌素水平(37名患者)或通过检测HLA-DQB1*0602(95%的HLA-DQB1*0602阳性患者伴有脑脊液水平降低)。所有患者和49%的正常对照都接受了整夜多导睡眠图检查和多次小睡潜伏期实验。【结果】发作性睡病患者的睡眠呼吸暂停低通气指数(AHI)较高(P=0.03),而睡眠时的最低氧饱和度较低(P=0.0002),这种差异与年龄、性别及BMI无关。与对照组(22%为DQB1*0602阳性)相比,发作性睡病患者对低氧的反应性显著降低(0.13±0.09 vs0.19±0.13,P<0.0001)。而在正常对照组中,DQB1*0602阳性者的△VE/△SaO也比DQB1*0602阴性者显著降低(0.13±0.08 vs 0.20±0.14,P=0.002)。且这种差异与AHI无关。但△VE/△PCO在发作性睡病患者和正常对照及DQB1*0602阳性者和阴性者之间无显著差异。【结论】猝倒型发作性睡病患者低氧反应性的降低与HLA-DQB1*0602有关。

关键词：发作性睡病化学反应性低O2 高CO2 HLADQB1

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Socio-Demographic Determinant of Yellow Fever Patient: A Retrospective Study (2020), Federal Medical Center, Asaba

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Journal of Biosciences and Medicines 2022年第12期10卷 225-238页

作者： Ngozi Esther Ezunu Joy Ifeyinwa Egeonu Ajiri Henry Osihro Uyi-Oghosa Onyemushani Said Abdulkareem Omole Clementina Oyakhire Onyema Edith Wayemeru Chidera Olivia Okey-Ezufo Chikadibia Eze-Otulaka Faith Inegbejie Clever Ajiri Oghale Diana Chinenye Ofomata Grace Nnenna Onubogu Orhomuromo Paul Okpomo Eguolo Unique Okorhi Onobhase Theresa Agbele Anastacia Okwudili Ojimba Adesuwa Queen Aigbokhaode Francis Chinedu Ugoeze Victor Azubike Osiatuma emmanuel Okechukwu Ezunu Obianuju Nkemjika Jisieike Erhinyaye Omoyibo Efe Department of Nursing Federal Medical Centre Asaba Nigeria CCDRC Federal Medical Centre Asaba Nigeria Department of Internal Medicine Federal Medical Centre Asaba Nigeria Department of Radiology Federal Medical Centre Asaba Nigeria Department of Health Info.mation Management Federal Medical Centre Asaba Nigeria Department of Pediatrics Federal Medical Centre Asaba Nigeria

Background: Yellow fever is transmitted primarily to humans and non-human primates through the bite of an infected female mosquito Aedes Spp. It is prevented mainly by vaccination. Method: This retrospective observational study at the Center for Communicable Disease Control and Research (CCDCR) Federal Medical Center Asaba (F.M.C) was conducted on all patients diagnosed and managed with yellow fever in the year 2020. We studied a total number of 57 patients’ case files seen within the period. A chi-square test was done to test the null and alternative hypotheses. Result: About 48 (84.2%) males and female 9 (15.8%) females were mostly affected and gender was significant with a chi-squared value of 26.6 and p-value of 0.00. Conclusion: To eradicate this virus, vaccination and health promotions should be encouraged by the health care workers supported by the government. This is to ensure that a greater proportion of the affected community can be immunized.

关键词： Yellow Fever Socio-Demograpic Determinants Asaba

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学前教育中的同龄和混龄教育组织形式

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幼儿教育（教育科学） 2018年第6期 3-7,17页

作者：瓦西里奥斯·伊曼努埃尔·菲纳克思张虹(译) 胡亿军(译) 德国巴伐利亚学前教育研究所慕尼黑浙江师范大学杭州幼儿师范学院杭州310012 浙江外国语学院德国研究中心杭州310012

梳理当下通行的各种早期儿童教育组织形式发现，混龄教育对儿童社会发展素养的培养具有较大的优势。菲纳克思方案综合运用同龄和混龄两种教育组织形式，并采用独特的幼儿园园舍设计方式，是幼儿园教育组织形式创新的一种积极尝试。

关键词：同龄教育混龄教育社会发展素养菲纳克思方案

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国际视野下的学前教育课程发展

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幼儿教育（教育科学） 2017年第11期 3-10,24页

作者：瓦西里奥斯·伊曼努埃尔·菲纳克思胡亿军张虹德国巴伐利亚学前教育研究所慕尼黑浙江外国语学院德国研究中心杭州310012 浙江师范大学杭州幼儿师范学院《幼儿教育》编辑部杭州310012

自上世纪90年代开始，世界各国政府对本国学前教育课程发展的影响越来越大。以现代建构主义“自我发展”儿童观为指导的第一代学前教育课程慢慢被以后现代社会建构主义“合作建构”儿童观为指导的第二代学前教育课程所取代。第二代学前... 详细信息

自上世纪90年代开始，世界各国政府对本国学前教育课程发展的影响越来越大。以现代建构主义“自我发展”儿童观为指导的第一代学前教育课程慢慢被以后现代社会建构主义“合作建构”儿童观为指导的第二代学前教育课程所取代。第二代学前教育课程强调异质性所具有的意义、强调学习和教育是一个社会过程、强调从开端开始强化儿童的素养。这些体现的是后现代的特征。对异质性的理解和应对、主张强化儿童的强项、强调以评估保证教育的高质量等则体现了第二代课程的基本特点。

关键词：学前教育课程后现代异质性合作建构

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Evaluation of the Antidiabetic Activity and Toxicological Properties of Hippocratea Velutina (Afzel.)

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Clinical Complementary Medicine and Pharmacology 2023年第2期3卷 50-56页

作者： Farouk A.Oladoja emmanuel SIrokosu Marcus D.Ayoola Oyinloye O.Elijah Murtala A.Akanji Ogunleye T.Beatrice Odewo A.Samuel Department of Pharmacology and Toxicology Faculty of PharmacyOlabisi Onabanjo UniversityAgo-Iwoye 121102Ogun-State.Nigeria Department of Pharmacology and Therapeutics Faculty of Basic Medical ScienceOlabisi Onabanjo University.Ago-Iwoye 121102Ogun-State.Nigeria Department of Pharmacognosy Faculty of PharmacyObafemi Awolowo University Ile-Ife 220282Osun-State.Nigeria Forest Research Institute of Nigeria Ibadan 200221Oyo-State.Nigeria

Background:Hippocratea velutina(HV)is a novel plant folklorically used for lowering blood glucose,hence a potential source of new antidiabetic ***:The study evaluated the anti-diabetic potentials of the methanol extract of Hippocratea velutina leaf and its toxicity profile in mice and ***:Acute and subacute toxicity tests of the plant extract were carried out by using a modified OECD *** antidiabetic activity in streptozotocin-induced diabetic rats at 50,150,and 300 mg/kg for 28 days was assayed,while glibenclamide(5 mg/kg)and distilled water were the positive and negative controls,*** examination of vital organs was also carried ***:Preliminary phytochemical screening of the leaf extract showed the presence of tannins,flavonoids,saponins,alkaloids,terpenoids,deoxy-sugars,and anthraquinones in *** extract had LD 50 greater than 2000 mg/kg in *** had no toxic effects on the haematological and biochemical components from blood samples collected but caused significant blood glucose level reduction in normal rats at 150 and 300 mg/*** streptozotocin-induced diabetic rats,the extract elicited a non-dose-dependent antidiabetic effect on day seven at all the tested doses,significantly higher than glibenclamide(10 mg/kg).However,on days 14,21,and 28,the extract activity at all the tested doses and glibenclamide were *** extract did not affect the liver,brain,kidney,and pancreas histology at 200 mg/kg but caused slight and severe effects on these organs at 400 and 800 mg/kg,***:The study concluded that Hippocratea velutina possessed antihyperglycaemic activity and was non-toxic at low doses but could have deleterious effects to the liver and kidney at high concentrations.

关键词： Hippocratea Velutina Diabetes mellitus Haematological and biochemical parameters

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