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砂岩中的成岩圈闭

国外油气勘探 1986年第5期 11-15页

作者： DouglasJ.cant 张绍海

在过去15年间,石油地质学家对砂岩的成岩作用和其他沉积物中的有关变化的重要性已经有了更深入的认识。这方面的主要进展包括:(1)认识到砂岩中几乎普遍存在自生粘土矿物(Wilson和Pittman,1977);(2)次生孔隙的识别(Schmidt等,1977);(3)... 详细信息

在过去15年间,石油地质学家对砂岩的成岩作用和其他沉积物中的有关变化的重要性已经有了更深入的认识。这方面的主要进展包括:(1)认识到砂岩中几乎普遍存在自生粘土矿物(Wilson和Pittman,1977);(2)次生孔隙的识别(Schmidt等,1977);(3)加深了对

关键词：砂岩渗透率成岩圈闭孔隙度碎屑岩孔隙率油气圈闭成岩作用地质作用

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玉米抽丝期夜温影响玉米着粒数

国外作物育种 1999年第4期18卷 38-42页

作者： cant.,MG 邱敦莲

Clinical Parameters in the First 5 Minutes after Birth Have a Predictive Value for Survival of Extremely Preterm Infants

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Maternal-Fetal Medicine 2023年第4期5卷 244-247页

作者： Laura Torrejón-Rodríguez Álvaro Solaz-García Inmaculada Lara-cantón Alejandro Pinilla-González Marta Aguar Máximo Vento Division of Neonatology University and Polytechnic Hospital La Fe(HULAFE)Valencia 46026Spain Neonatal Research Group Instituto de Investigación Sanitaria La Fe(IISLAFE)Valencia 46026Spain

Extreme preterm infants(60%)and lower(<30%)initial FiO_(2).Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement ... 详细信息

Extreme preterm infants(60%)and lower(chievement of arterial oxygen saturation measured by pulse oximetry≥85%at 5 minutes after *** clinical trials comparing higher versus lower initial FiO_(2)have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.

关键词： Extreme preterm Postnatal stabilization Oxygen saturation Heart rate Inspired fraction of oxygen Apgar score

Purification of the Drosophila melanogaster Proteins Inscuteable and Staufen Expressed in Escherichia coli

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Advances in Bioscience and Biotechnology 2015年第7期6卷 485-493页

作者： Xristo Zárate Megan M.McEvoy Teresa Vargas-Cortez Jéssica J.Gómez-Lugo Claudia J.Barahona Elena cantú-Cárdenas Alberto Gómez-Trevino Universidad Autónoma de Nuevo León Facultad de Ciencias QuímicasCd.UniversitariaSan Nicolás de los GarzaMéxico Department of chemistry and Biochemistry University of ArizonaTucsonUSA

The proteins Inscuteable and Staufen are key components during asymmetric cell division of neuroblasts for the development of Drosophila melanogaster. Expression and purification of both proteins has been a difficult task for structure-function studies. Based on codon optimization for protein expression in Escherichia coli, we have been able to produce, in soluble form, the C-terminal domains of Inscuteable and Staufen as chimeras with N-terminal maltose binding protein tag that contains a rigid linker between them for feasible crystallization. In addition, using an optimized synthetic gene, corresponding to the amino acid region 250 - 623 of Inscuteable fused to glutathione-S-transferase, low-scale expression experiments showed production of soluble protein. Finally, eukaryotic expression of Inscuteable in the methylothropic yeast Pichia pastoris failed to produce the Drosophila protein at detectable amounts, reinforcing the fact that E. coli still was the microorganism of choice for high-yield protein expression.

关键词： Inscuteable Staufen Protein Expression and Purification Maltose-Binding Protein Escherichia coli

Parsonage-Turner syndrome following chikungunya virus infection:A case report

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Asian Pacific Journal of Tropical Medicine 2019年第5期12卷 239-242页

作者： Luis Arthur Brasil Gadelha Farias Marina Vasconcelos Sampaio Ant?nio Carlos Delgado Sampaio Roberto da Justa Pires Neto Jorge Luiz Nobre Rodrigues School of Medicine,Federal University of Ceará School of Medicine,Universitary Center christus(Unichristus) Orthopedic Department,S?o Carlos Hospital Hospital S?o Joséde Doen?as Infecciosas Infectology Service,Walter cantídeo University Hospital School of Medicine Federal University of Ceará School of Medicine Universitary Center Christus(Unichristus) Orthopedic Department Sao Carlos Hospital Hospital Sao José de Doencas Infecciosas Infectology Service Walter Cantídeo University Hospital

Rationale: Parsonage-Turner syndrome is a rare syndrome of unknown etiology, affecting mainly the lower motor neurons of the brachial *** fever is a mosquito-borne viral disease characterized by acute fever and polyarthritis/*** concerns: A 54-year-old Brazilian male patient who presented with a 2-day history of fever(temperature 38.8 ℃), arthralgia, erythematous rash, diffuse osteomuscular pain and headache, which evolved into left shoulder pain associated with morning ***: Parsonage-Turner syndrome and chikungunya ***: Symptomatic treatment(a combination of short-acting dypirone(500 mg every 6 h) and slow-release opioids(tramadol 100 mg every 4 h) and physiotherapy/rehabilitation with ***: The patient was improved and discharged, remaining with symptomatic treatment and physiotherapy/***: To the best of our knowledge, there were no reports of Parsonage-Turner syndrome following chikungunya virus *** of the possibility of this rare association is *** present case report highlights the importance of awareness of this association as a new cause of morbidity in patients with chikungunya virus infection.

关键词： Parsonage-Turner syndrome chikungunya virus chikungunya fever Brachial amyotrophy Case report

部分涂层金属支架治疗继发于慢性胰腺炎的症状性胆总管狭窄:一项初步研究

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世界核心医学期刊文摘（胃肠病学分册） 2005年第11期1卷 27-28页

作者： cantù P. Hookey L.C. Morales A. J. Deviè re 尹勇 Department of Gastroenterology Erasme University Hospital Rue de Lennik 808 1070 Brussels BelgiumDr.

Background and study aims: Although surgery remains the gold standard for the treatment of symptomatic common bile duct stenosis associated with chronic pancreatitis, plastic and self-expandable open-mesh stents have been proposed as alternative treatments. These may dysfunction, however, mainly due to stent occlusion by clogging or by hyperplasia of inflammatory tissue. The aim of this study was to evaluate the safety and long-term results of using partially covered metal stents in this setting. Patients and methods: A total of 14 patients (12 men, 2 women; mean age 50 ± 3 years) underwent partially covered metal stent insertion for common bile duct stenosis secondary to chronic pancreatitis (12 alcohol-related, two idiopathic). They had all been treated previously with plastic prostheses. Results: Either a 40-mm (n = 13) or a 60-mm (n = 1) partially covered metal stent was placed, depending on the length of the common bile duct stenosis and the level of the cystic duct bifurcation. Stent placement was successful, with resolution of cholangitis and improvement in cholestasis, in all patients. During the median follow-up period of 22 months (range 12- 33 months)- seven patients developed dysfunction of the stent and required re-treatment. At 12, 24, and 30 months, the stent patency rates were 100% , 40% , and 37.5% respectively. Conclusions: While partially covered metal stenting is safe and effective for the initial treatment of chronic pancreatitis-associated common bile duct stenosis and shows promising short-term results, long-term data show that dysfunction occurs in 50% of cases. In light of the continued interest in nonsurgical treatment of this condition, further research is warranted to investigate new stent designs with improved long-term patency.

关键词：慢性胰腺炎胆总管狭窄金属支架胆管支架远期通畅率外科手术功能障碍炎性组织短期疗效胆汁淤积

营养素和激素通过哺乳动物雷帕霉素靶标信号通路调控乳蛋白合成

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饲料与畜牧（新饲料） 2012年第12期 24-28页

作者： S.A.Burgos M.Dai J.P.cant 季昀庞学燕不详扬州大学动物科学与技术学院

营养物质和内分泌虽能影响奶牛乳蛋白的合成,但至今这种调控作用的分子机制仍未完全阐明。本研究的目的是测定营养物质和激素是否是通过哺乳动物雷帕霉素靶标(mTOR)信号通路调控乳蛋白合成。试验从泌乳奶牛乳腺组织中分离乳腺腺泡,用含... 详细信息

营养物质和内分泌虽能影响奶牛乳蛋白的合成,但至今这种调控作用的分子机制仍未完全阐明。本研究的目的是测定营养物质和激素是否是通过哺乳动物雷帕霉素靶标(mTOR)信号通路调控乳蛋白合成。试验从泌乳奶牛乳腺组织中分离乳腺腺泡,用含有氨基酸(AA)、葡萄糖和乙酸(GA)或催乳激素(HIP)以其混合物的培养基处理腺泡,然后测定乳蛋白合成速率和mTOR信号通路中各元件的磷酸化状态。结果发现,培养基添加AA后可使乳蛋白合成率提高50%,而单独添加GA或HIP不影响乳蛋白合成。HIP可以增强AA调控乳蛋白合成,但GA没有增强AA的这种作用。HIP可诱导蛋白激酶B发生磷酸化,而且当AA或GA存在时,HIP能增强这种磷酸化作用。AA和HIP对乳蛋白合成的促进作用与mTOR的底物磷酸化有关,即与p70核糖体蛋白S6激酶-1和真核起始因子4E(eIF4E)结合蛋白-1(4E-BP1)的磷酸化有关。结果表明,营养物质和激素可能通过mTOR信号通路调控乳蛋白合成。

关键词：蛋白质合成哺乳动物雷帕霉素靶标乳腺

1998～2000年英国和爱尔兰儿童严重食物过敏反应的发病状况

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世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 28-29页

作者： Colver A.F. Nevantaus H. Macdougall C.F. cant A.J. 李开 Northumbria H ealthcare NHS Trust and University of Newcastle Upon Tyne Sir James Spence Inst itute Royal Victoria Infirmary Newcastle upon Tyne NE1 4LP United Kingdom

Aim: Medical and lay concerns about food allergy are increasing. Whilst food a llergy may be becoming more common, fatal reactions to food in childhood are ver y rare and their rate is not changing. We sought to establish how common severe reactions are. Methods: Prospective survey, 1998 to 2000, of hospital admissions for food-allergic reactions-conducted primarily through the British Paediatri c Surveillance Unit, covering the 13 million children in the United Kingdom and Ireland. Results: 229 cases reported by 176 physicians in 133 departments, yield ing a rate of 0.89 hospital admissions per 100 000 children per year. Sixty-fiv e per cent were male, 41%were under 4 y and 60%started at home. Main allergens were peanut (21%), tree nuts (16%), cow’s milk (10%) and egg (7%). Main sy mptoms were facial swelling (76%), urticaria (69%), respiratory (66%), shock (13%), gastrointestinal (4%). Fiftyeight cases were severe. Three were fatal, six near fatal, and 8 of these 9 had asthma with wheeze being the life-threaten ing symptom. Three near-fatal cases received excess intravenous epinephrine. No ne of the non-fatal reactions resulted in mental or physical impairment. Seven of 171 non-severe and 6/58 severe cases might have had a worse outcome if epine phrine auto-injectors had been unavailable. Six of the severe cases might have benefited if auto-injectors had been more widely prescribed. Conclusion: In the United Kingdom and Ireland, the incidence of severe reactions is low. The study highlights that: asthma is a strongly significant risk factor for a severe reac tion and therefore warrants optimal management; severe wheeze is a prominent fea ture of severe reactions and warrants optimal management; intravenous epinephrin e should be used with great care if needed. Epinephrine auto-injectors do not a lways prevent death, but our study design and data do not allow a definite state ment about whether overall they are beneficial.

关键词：发病状况食物过敏自动注射器发性食物肠道症状儿科病房反应症状医学专业喘鸣前瞻性调查

内镜阴性的胃食管反流病患者胃排空加速和食管酸暴露的关系

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世界核心医学期刊文摘（胃肠病学分册） 2006年第11期2卷 59-60页

作者： Carmagnola S. Fraquelli M. cantùP. R. Penagini 张诗峰 IRCCS Ospedale Maggiore Pad Granelli Via F. Sforza 35 IT-20122 Milan Italy

Objective. A delay in gastric emptying has been reported in patients with gastro-oesophageal reflux disease (GORD),but its role in increasing the number of reflux episodes is still debated. The aim of this study was to assess the relationship between acceleration of gastric emptying and gastro-oesophageal reflux in patients with endoscopy-negative GORD and pathological oesophageal acid exposure. Material and methods. Twelve patients (7 M, age range 24-65 years) underwent 6-h postprandial (2.1 MJ meal) combi-ned gastric emptying by real-time ultrasonography and intr-a-oesophageal pH monitoring after cisapride (20 mg b.i.d.)and placebo for 3 days, on two separate occasions at least 7 days apart in double-blind randomized order. Gastric emptying after placebo was also measured in 12 healthy volunteers (7M, age range 25-54 years). Results. In the patients’ group, the area under the emptying time curve was greater (p changes in gastric emptying and in the reflux variables by linear regression analysis (R2 ch is not a major determinant of gastrooesophageal reflux.

关键词：胃食管反流内镜阴性胃排空时间西沙比利实时超声胃排空延迟时间百分比安慰剂随机双盲健康