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Journal of Genetics and Genomics 2015年第9期42卷 507-510页

作者： Zhou Tan Zhongkai Hu emily y.cai Cantas Alev Ting yang Zhen Li Joyce Sung yasser yehia El-Sayed Gary M.Shaw David K.Stevenson Atul J.Butte Guojun Sheng Karl G.Sylvester Harvey J.Cohen Xuefeng B.Ling Institute of Developmental and Regenerative Biology Hangzhou Normal University Department of Surgery Stanford University Lab for Early Embryogenesis RIKEN Center for Developmental Biology Department of Obstetrics and Gynecology Stanford University Department of Pediatrics Stanford University Stanford

Over 11% of all pregnancies in the US result in preterm birth, greatly contributing to perinatal morbidity and mortality （Goldenberg and Rouse, 1998）. Preterm birth etiologies remain largely unknown, and effective prevention methods have yet to be developed. The use of biofluid （e.g., serum or urine） for the analysis of the naturally occurring peptidome （MW 〈 4000） as a source of biomarkers has been reported for different diseases （Villanueva et al., 2006; Ling et al., 2010a, 2010b, 2010c, 2011）. Mass spectrometry-based profiling of naturally occurring peptides can provide an extensive in- ventory of serum peptides derived from either high-abundant endogenous circulating proteins or cell and tissue proteins （Liotta and Petricoin, 2006）.

关键词： Serological Targeted Analysis of an ITIH4 Peptide Isoform A Preterm Birth Biomarker and Its Associated SNP Implications SNP

Isolation of bacteria from fermented food and grass carp intestine and their efficiencies in improving nutrient value of soybean meal in solid state fermentation

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Journal of Animal Science and Biotechnology 2018年第3期9卷 664-673页

作者： Samantha Medeiros Jingjing Xie Paul W.Dyce Hugh y.cai Kees De Lange Hongfu Zhang Julang Li Department of Animal Bio Sciences University of Guelph State Key Laboratory of Animal Nutrition Institute of Animal SciencesChinese Academy of Agricultural Sciences Animal Science Department Auburn University Animal Health Laboratory University of Guelph College of Life Science and Engineering Foshan University

Background: Soybean meal is an excellent and cost-effective protein source; however, its usage is limited in the piglet due to the presence of anti-nutritional factors and the antigens glycinin and β-conglycinin. The objective of the current study was to screen and select for bacteria that can be efficiently adopted to ferment soybean meal in order to solve this ***: Bacteria were isolated from fermented soy foods and the grass carp intestine, and strains selected for high protease, cellulase and amylase activities. The isolated bacteria were characterized as Bacillus cereus, Bacillus subtilis and Bacilus amyloliquefacien, respectively. Fermentation with food-derived Isolate-2 and fish-derived F-9 increased crude protein content by 5.32% and 8.27%, respectively; improved the amino acid profile by increasing certain essential amino acids, broke down larger soy protein to 35 k Da and under, eliminated antigenicity against glycinin and β-conglycinin, and removed raffinose and stachyose in the soybean meal following a 24-h ***: Our results suggest these two B. amyloliquefaciens bacteria can efficiently solid state ferment soybean meal and ultimately produce a more utilizable food source for growing healthy piglets.

关键词： Allergens Fermentation Food source bacteria Soybean meal

Multiple ballistic impacts on 2024-T4 aluminum alloy by spheres:Experiments and modelling

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Journal of Materials Science & Technology 2021年第35期94卷 164-174页

作者： J.C.Cheng S.P.Zhao D.Fan H.W.Chai S.J.ye C.Li S.N.Luo y.cai J.y.Huang School of Materials Science and Engineering Southwest Jiaotong UniversityChengduSichuanP.R.China The Peac Institute of Multiscale Sciences ChengduSichuanP.R.China

Multiple ballistic impacts are carried out on a 2024-T4 aluminum alloy by spherical steel projectiles(5-mm diameter)at~400 m s^(-1),to investigate its dynamic deformation and *** ballistic impact process is captured with high-speed *** samples are characterized with optical imaging,three-dimensional laser scanning,microhardness testing and electron backscatter *** increasing number of impacts,crater diameter increases slightly,but crater depth and crater volume increase significantly,and strain accumulation leads to microhardness increase *** parameters all follow power-law relations with the number of ***-like deformation bands and macroscopic deformation twins are produced by impact as a result of spontaneous dislocation self-pinning under high strain rate,large shear *** multiple impacts,shear strain accumulation in the arc-shaped region of the crater induces deformation twinning when it exceeds a critical value(~1.1-1.6).It is highly possible that the deformation twins are related to deformation bands,since they both share one set of the{111}pole with the initial matrix grain.A finite element method model is optimized to reproduce experimental observations and interpret deformation mechanisms.

关键词： 2024Al-T4 alloy Multiple impacts Twin-like deformation band Deformation twinning Finite element method

Dynamic mechanical properties,deformation and damage mechanisms of eutectic high-entropy alloy AlCoCrFeNi_(2.1)under plate impact

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Journal of Materials Science & Technology 2023年第3期134卷 178-188页

作者： S.P.Zhao Z.D.Feng L.X.Li X.J.Zhao L.Lu S.Chen N.B.Zhang y.cai S.N.Luo The Peac Institute of Multiscale Sciences ChengduChina Key Laboratory of Advanced Technologies of Materials Ministry of EducationSouthwest Jiaotong UniversityChengduChina

Shock compression and spallation of a eutectic high-entropy alloy(HEA)AlCoCrFeNi_(2.1)with lamellar structure are investigated via plate impact loading with free-surface velocity *** as-cast and postmortem samples are characterized with transmission electron microscopy,electron back-scatter diffraction and scanning electron *** accurate Hugoniot equation of state is ***-ter shock compression to∼12 GPa,both the L1_(2)and B_(2)phases retain their ordered *** dislocations in the{111}slip planes,stacking faults and deformation twins are found in the L1_(2)phase,along with fewer dislocations in the{110}slip bands in the B(2)***-induced deformation twin-ning within the L1_(2)phase of this HEA is observed as a new deformation mechanism under various load-ing *** spallation,both ductile and brittle damage modes are *** micro voids and cracks prefer to nucleate at the phase boundaries chiefly,then in the B(2)*** similar shock stress,the spall strength of AlCoCrFeNi_(2.1)HEA is about 40%higher than those of other reported dual-phase HEAs due to the high stability of its semi-coherent phase boundaries.

关键词： High-entropy alloy Hugoniot Spall damage Microstructure

Simulation of plastic deformation induced texture evolution using the crystallographic homogenization finite element method

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Acta Mechanica Solida Sinica 2017年第1期30卷 51-63页

作者： y.P.Chen y.y.cai Department of Mechanics Huazhong University of Science and Technology

A semi-implicit elastic/crystalline viscoplastic finite element（FE） method based on a ＂crystallographic homogenization＂ approach is formulated for a multi-scale analysis. In the formulation, the asymptotic series expansion is introduced to define the displacement in the micro-continuum. This homogenization FE analysis is aimed at predicting the plastic deformation induced texture evolution of polycrystalline materials, the constituent microstructure of which is represented by an assembly of single crystal grains. The rate dependent crystal plasticity model is adopted for the description of microstructures. Their displacements are decomposed into two parts： the homogenized deformation defined in the macrocontinuum and the perturbed one in the micro-continuum. This multi-scale formulation makes it possible to carry out an alternative transition from a representative micro-structure to the macro-continuum. This homogenization procedure satisfies both the compatibility and the equilibrium in the micro-structure. This developed code is applied to predict the texture evolution, and its performance is demonstrated by the numerical examples of texture evolution of FCC polycrystalline metals.

关键词： Homogenization Local periodicity Crystalline plasticity Texture Finite element

SURFACE MODIFICATION OF TITANIUM FILMS WITH SODIUM ION IMPLANTATION:SURFACE PROPERTIES AND PROTEIN ADSORPTION

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Acta Metallurgica Sinica(English Letters) 2007年第2期20卷 148-156页

作者： K. y. cai College of Bioengineering Chong Qing University Chongqing 400044 China

Sodium implanted titanium films with different ion doses were characterized to correlate their ion implantation parameters. Native titanium films and ion implanted titanium films were characterized with combined techniques of X-ray photoelectron spectroscopy （XPS）, atomic force microscopy （AFM）, and light microscopy （LM）. The surface presented increased sodium concentration on treated titanium films with ion dose increasing, except for the group with the highest ion dose of 4×10^17ions/cm^2. XPS depth profiling displayed that sodium entered titanium film around 25-50nm depth depending on its implantation ion dose. AFM characterization showed that sodium ion implantation treatment changed the surface morphology from a relatively smooth titanium film to rough surfaces corresponding to different implantation doses. After sodium implantation, implanted titanium films presented big particles with island structure morphology. The surface morphology and particle growth displayed the corresponding trend. Fibrinogen adsorption on these titanium films was performed to correlate with the surface properties of treated titanium films. The results show that protein adsorption on ion-implanted samples with dose of 2×10^17 and 4×10^17 are statistically higher （p 〈0.01） than samples treated with dose of 5×10^16 and 1×10^17, as well as the control samples.

关键词： titanium film sodium ion implantation protein adsorption surface characterization

Perception of Potential Health Risk of Climate Change and Utilization of Fans and Air Conditioners in a Representative Population of Hong Kong

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International Journal of Disaster Risk Science 2020年第1期11卷 105-118页

作者： yang Gao emily y.y.Chan Holly C.y.Lam Aiwei Wang Department of Sport and Physical Education Hong Kong Baptist UniversityHong KongChina Collaborating Centre for Oxford University and CUHK for Disaster and Medical Humanitarian Response The Jockey Club School of Public Health and Primary CareThe Chinese University of Hong KongHong KongChina

Climate change, especially as reflected in heat waves, is a rising threat worldwide. Appropriate use of cooling devices can protect people from health impacts during a heat wave. A population-based telephone survey was conducted in a representative sample of residents in Hong Kong to investigate ownership and use of domestic cooling devices, identify correlates, and examine their associations with risk perception of potential health impact of climate change. More than 90% of the 1002 respondents owned and used cooling devices at home. The majority(57.7%) perceived the potential health risk of climate change at a high level. However, risk perception had no relationship with ownership and utilization of cooling devices. Old people(≥ 65 years), the low-educated, those with low income, and those with chronic diseases were more likely not to use air conditioners when feeling *** findings suggest that there are no signs showing people have taken more protective actions although half of respondents recognized climate change as a threat. Familial economic condition may be a major determinant in ownership and use of air conditioners at home. Old people and those with chronic diseases are at high risk of adverse exposure to climate change and therefore should be equipped with appropriate measures to use cooling devices.

关键词： Climate change Domestic cooling device Heat wave health impact Hong Kong Risk perception

A method for analyzing on-line video images of crystallization at high-solid concentrations

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Particuology 2008年第1期6卷 9-15页

作者： Jian Wan cai y. Ma Xue Z. Wang Institute of Particle Science and Engineering School of Process Environmental and Materials Engineering University of Leeds Leeds LS2 9JT UK

Recent research has demonstrated that on-line video imaging is a very promising technique for monitoring crystallization processes. The bottleneck in applying the technique for real-time closed-loop control is considered as image analysis that needs to be robust, fast and able to handle varied image qualities due to temporal variations of operating conditions such as mixing and solid concentrations. Image analysis at highsolid concentrations turns out to be extremely challenging because crystals tend to overlap or attach to each other and the boundaries between the crystals are usually ambiguous. This paper presents an image segmentation algorithm that can effectively deal with images taken at high-solid concentrations. The method segments crystals attached to each other along the mostly related concave points on the contours of crystal blocks. The detailed procedure is introduced with application to crystallization of L-glutamic acid in a hot-stage reactor.

关键词： Crystallization High-solid concentrations Image processing Multi-scale segmentation Watershed segmentation Crystal size distribution

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提高活性染料染棉可染性的一种新方法

国外纺织技术 2000年第7期 20-26页

作者： y.cai 单瑛滑钧凯

饲喂豆饼粉——玉米基础日粮的河鲇鱼蛋氨酸需要量

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国外畜牧学（饲料） 1997年第1期 9-14页

作者：金光明 y.cai

应用豆饼粉—玉米基础日粮测定,25℃时42天试验期中14克河鲇鱼日粮蛋氨酸(Met)的需要量。与鲇鱼体成分氨基酸有关的平衡限制氨基酸基础日粮含277克CP、3.6克Met、4.0克胱氨酸(Cys)和10MJDE/kgDM。在谷氨酸缺乏时,DL—蛋氨酸按0～12克/千... 详细信息

应用豆饼粉—玉米基础日粮测定,25℃时42天试验期中14克河鲇鱼日粮蛋氨酸(Met)的需要量。与鲇鱼体成分氨基酸有关的平衡限制氨基酸基础日粮含277克CP、3.6克Met、4.0克胱氨酸(Cys)和10MJDE/kgDM。在谷氨酸缺乏时,DL—蛋氨酸按0～12克/千克,间隔 2克添加到基础日粮中形成7种等氮和等能日粮。对照日粮含331克CP、8克Met、5克Cys和10MJDE/kgDM(包括8％鱼粉),7种等级Met水平日粮在增重、特定生长率、饲料或GE摄入量、饲料或能量利用率、蛋白质或能量潴留、蛋白质利用率、表观净蛋白质或能量利用方面产生了二次方式反应(P<0.01)。根据多重回归剂量——反应模式,河鲇鱼需要9.4克Met/kgDM(34.1克/千克CP)和11.3克/千克计算可消化含硫氨基酸,或根据蛋白质增加与Met摄入的断线反应需要270mgMet/kg·鱼·日。在全价Met水平时,鲇鱼具有最低肝脂(P<0.05),表明饲料摄入量和蛋白质或能量利用率与饲喂对照日粮鲇鱼相同。饲喂所有植物蛋白质日粮鲇鱼需要日粮蛋氨酸较以前报道高,饲喂玉米——豆饼粉日粮添加全价蛋氨酸的鲇鱼产生的生长性能与饲喂鱼粉基础日粮相似。

关键词：豆饼粉玉米鲇鱼蛋氨酸