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Difficulties in Recruitment for a Randomised Controlled Trial of Lifestyle Intervention for Type 2 Diabetes: Implications for Diabetes Management

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Open Journal of Endocrine and Metabolic Diseases 2012年第4期2卷 53-57页

作者： George A. Jelinek emily hadgkiss Craig Hassed Bernard Crimmins Peter Schattner Danny Liew Rick Kausman Warrick J. Inder Siegfried Gutbrod Tracey J. Weiland Department of General Practice Faculty of Medicine Nursing and Health Sciences Monash University Clayton Australia Department of Medicine Faculty of Medicine and Health Sciences The University of Melbourne Royal Melbourne Hospital Melbourne Australia East Bentleigh General Practice Melbourne Australia Emergency Practice Innovation Centre St Vincent’s Hospital Melbourne Australia Formerly Department of Endocrinology St Vincent’s Hospital Melbourne Australia Manningham General Practice Melbourne Australia The Butterfly Foundation Malvern Australia The Gawler Foundation Yarra Junction Australia

Objective: To report our experience of attempting a randomised controlled trial of an intensive lifestyle intervention for early type 2 diabetes delivered in a residential setting. Methods: We established a trial requiring 84 participants (46 standard care and 38 intervention) to detect a 1% difference in HbA1c between intervention and control groups at 12 months, allowing for attrition. Ethics approval was obtained from Monash University. Results: The study was abandoned after five months of consistent promotion due to recruitment failure (four subjects recruited). Conclusion: It appears to be difficult for patients with diabetes to commit to a live-in period of education regarding lifestyle modification as a means of treating the illness. We recommend better education of patients and their doctors about the potential health benefits of lifestyle change to manage type 2 diabetes, and further research into novel methods of delivering lifestyle advice which are both effective and sustainable.

关键词： Type 2 Diabetes Mellitus Randomised Controlled Trial Management Lifestyle Risk Factors

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Difficulties in Recruitment for a Randomised Controlled Trial of Lifestyle Intervention for Type 2 Diabetes: Implications for Diabetes Management

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Open Journal of Endocrine and Metabolic Diseases（内分泌与新陈代谢疾病期刊） 2012年第4期

作者： George A. Jelinek emily hadgkiss Craig Hassed Bernard Crimmins Peter Schattner Danny Liew Rick Kausman Warrick J. Inder Siegfried Gutbrod Tracey J. Weiland

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