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Non-operative management of rectal cancer: Highlighting the controversies

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1501-1506页

作者： Sameh Hany emile Anjelli Wignakumar Department of Colorectal Surgery Cleveland Clinic FloridaWestonFL 33331United States

There remains much ambiguity on what non-operative management(NOM)of rectal cancer truly entails in terms of the methods to be adopted and the best algorithm to *** is clearly shown by the discordance between various national and international guidelines on NOM of rectal *** main aim of the NOM strategy is organ preservation and avoiding unnecessary surgical in-tervention,which carries its own risk of morbidity.A highly specific and sensitive surveillance program must be devised to avoid patients undergoing unnecessary surgical *** many studies,NOM,often interchangeably called the Watch and Wait strategy,has been shown as a promising treatment option when undertaken in the appropriate patient population,where a clinical complete res-ponse is ***,there are no clear guidelines on patient selection for NOM along with the optimal method of surveillance.

关键词： Non-operative Management Rectal cancer Highlighting Controversies

Toward less invasive coloproctology: The future is out there

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World Journal of Gastroenterology 2024年第3期30卷 199-203页

作者： Sameh Hany emile Jonathan Ragheb Department of Colorectal Surgery Cleveland Clinic FloridaWestonFL 33331United States Department of Gastroenterology and Hepatology Cleveland Clinic FloridaWestonFL 33331United States

Medical care has undergone remarkable improvements over the past few *** of the most important innovative breakthroughs in modern medicine is the advent of minimally and less invasive *** trend towards employing less invasive treatment has been vividly shown in the field of gastroenterology,particularly *** to foregut interventions,colorectal surgery has shifted towards a minimally invasive ***,including both medical and surgical management of colorectal diseases,has undergone a remarkable paradigm *** treatment of both benign and malignant colorectal conditions has gradually transitioned towards more conservative and less inva-sive *** interesting paradigm shift was the trend to avoid the need for radical resection of rectal cancer altogether in patients who showed complete response to neoadjuvant *** trend of adopting less invasive appro-aches to treat various colorectal conditions does not seem to be stopping soon as further research on novel,more effective and safer methods is ongoing.

关键词： Toward Less invasive Minimally invasive Coloproctology Future Colorectal surgery

Usefulness of a Clinico-Biological Francois’Score in the Diagnosis of Acute Appendicitis:Experience of the University Hospital Center of Parakou,Benin

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Surgical Science 2018年第3期9卷 91-96页

作者： Montcho Adrien Hodonou Bio Tamou-Sambo Salako Alexandre Allode Roméo Romaric Gbédolo Djifid Morel Séto Selome Romaric Tobome Moise Francis Dossou Dodji emile mensah Department of Surgery and Specialties Teaching HospitalMedicine SchoolUniversity of ParakouParakouBenin Saint John of God Hospital Center of Tanguieta TanguietaBenin Teaching Hospital of Porto-Novo Faculty of Health ScienceUniversity of Abomey CalaviCotonouBenin

Introduction: Diagnostic wanderings of acute appendicitis are responsible for serious complications or abusive appendectomies. Existing Clinico-biological scores are efficient. Objective: To determine the diagnostic efficiency of Fran?ois’ score in acute appendicitis. Methodology: over 10 months, all the patients admitted in the CHUD-Parakou Emergency Department for pain in the right iliac fossa had been examined by resident students who calculated Fran?ois’ score. After verification by the surgeon, patients were put into three categories: category 1 score ≥ 2;category 2, score between -6 and 2;category 3, score below -6. Sensitivity and specificity were calculated. Results: out of 54 patients selected (29 men and 25 women), 29 were classified as group 1;19 as group 2 and 6 as group 3. An ultrasound was performed in all patients in group 2, and signs in favor of appendicitis were found in 12 patients. Of the 41 appendicectomies performed, the histologic analysis of 33 operative specimens found a pathological appendix. Sensitivity, specificity and negative predictive value per group were 100%. It has prevented almost in one every four patients (24.07%) an abusive appendectomy. Conclusion: This score would reduce diagnostic wanderings and target patient groups for imaging studies.

关键词： Acute Appendicitis Francois Score Sensitivity Specificity Resource-Limited Countries

A tribo-chemical view on astringency of plant-based food substances

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Friction 2024年第7期12卷 1392-1407页

作者： Samuel S.GAMANIEL Paloma S.DUEÑAS ROBLES Hans TROMP Els H.A.de HOOG Sissi de BEER emile van der HEIDE Laboratory for Surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 LWthe Netherlands NIZO Food Research B.V. Ede6710 BAthe Netherlands Department of Molecules and Materials MESA+Institute for Nanotechnology University of TwenteEnschede 7500 AEthe Netherlands

Consumption of plant-based food products having high composition of polyphenols leads to the sensation of *** sliding oral surfaces,friction is an essential property during the oral perception of roughness and dryness which are attributes associated with *** factors including the chemical composition of interacting layers,structure and operation of interfaces have an effect on the astringency development *** manner of interactions occurring at oral interfaces suggest there is a system dependence of astringency and highlights the importance of adopting a tribosystems *** measurement techniques have shown an existing relationship between salivary protein-polyphenol interaction and an astringent ***,the tribo-chemistry involved in this multifaceted sensation remains largely unexplored in a comprehensive *** this review the underlying tribo-chemical processes useful in understanding the mechanism of astringency are highlighted and discussed considering current techniques employed to investigate astringency *** of lubrication on oral surfaces owing to the tribo-chemical interactions involving saliva and astringent plant proteins requires subsequent deformations of oral tissues which are significant enough to induce strains at mechanoreceptor locations,leading to the sensation of *** is proposed that micro-scale contact modelling on the interaction of food particles/aggregates,boundary layers and oral surfaces shows potential in addressing the knowledge gap between tribo-chemical measurement techniques and panel tests,making it possible to attain a predictor for astringency.

关键词： oral lubrication astringency tribo-chemistry tribology

Papillary Carcinoma on Stroma Ovarii: A Case Report from Madagascar and Review of the Literature

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Journal of Cancer Therapy 2024年第3期15卷 57-61页

作者： Toky Rakotoarivo Christiana Ranaivoson Vonjy Andrianarison Nomeharisoa Rodrigue emile Hasiniatsy Florine Rafaramino Department of Oncology University Hospital Tanambao Antsiranana Madagascar Department of Oncology University Hospital Joseph Ravoahangy Andrianavalona Antananarivo Madagascar Department of Radiotherapy University Hospital Joseph Ravoahangy Andrianavalona Antananarivo Madagascar Department of Oncology and Pallliative Care Soavinandriana Hospital Center Antananarivo Madagascar

A 64-year-old woman with no particular history presented with chronic pelvic pain since November 2021. The ultrasound performed showed multiple right ovarian cystic ranging from 0.4 to 4 cm on the long axis. She underwent a right salpingo-oophorectomy in May 2022. The anatomical pathology result is in favor of a papillary carcinoma developed on stroma ovarii. No adjuvant treatment was necessary since the tumor was well limited, without capsular rupture, stage IA. The thyroid test was normal. The patient is currently being monitored. There is no sign of recurrence 20 months after surgery.

关键词： Papillary Carcinoma Surgery Struma Ovarii

Successful Laparoscopic Management of a Migrated Intrauterine Contraceptive Device in the Pelvic Cavity: A Case Report

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Open Journal of Obstetrics and Gynecology 2024年第1期14卷 36-43页

作者： Tompeen Isidore Inna Rakya Tchounzou Robert Neng Humphry Mangala Georges Tchenté Charlotte Mboudou emile Department of Gynecology and Obstetrics Faculty of Medicine and Biomedical Sciences The University of Yaoundé I Yaoundé Cameroon Department of Gynecology and Obstetrics Faculty of Medicine and Biomedical Sciences The University of Garoua Garoua Cameroon Department of Gynecology and Obstetrics Faculty of Health Sciences The University of Buea Buea Cameroon Department of Gynecology and Obstetrics Faculty of Medicine and Pharmaceutical Sciences The University of Douala Douala Cameroon

Background: An Intrauterine device (IUD) is a long-acting reversible contraceptive commonly used in clinical practice. Its insertion in the uterus is simple and safe. But sometimes, complications can occur. Case Report: Herein, we report a case of successful laparoscopic removal of a missing IUD Copper-T, mis-inserted in a 32-year-old woman, 4 months after she delivered by caesarian section, and presented persistent lower abdominal pain lasting 6 months. Uterine ultrasound was unremarkable, but a plain abdominopelvic X-ray confirmed the presence of the Copper-T inside the abdominal cavity. Conclusion: Insertion of IUD is simple and safe. When the diagnosis of uterine perforation following its insertion is clinically suspected and radiologically confirmed, laparoscopy, when available, remains one of the best options for removal.

关键词： IUD Ectopic Migration Contraception Laparoscopy

Comparative Study of the Physicochemical Quality of the Waters of the Méné River (Sassandra Watershed, Ivory Coast) in the Dry Season and in the Rainy Season

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Journal of Environmental Protection 2024年第6期15卷 738-746页

作者： Konan Lopez Kouamé Gansso Valentin Akilinon Olivier Simon Mananga Kombo Gneneyougo emile Soro Bi Tié Albert Goula Science and Technology Department Alassane Ouattara University Bouak Ivory Coast Environmental Sciences Laboratory Nangui Abrogoua University Abidjan Ivory Coast

The study carried out on the waters of the Méné River led to an overall assessment of its water quality during the dry season and the rainy season. The analysis focused on eight (8) water samples taken from the river during a period of dry season (January-February) and a period of rainy season (June and September). The various physicochemical parameters were measured according to Afnor standardized methods. The readings of temperature, turbidity, pH and conductivity made it possible to account for the disturbances occurring in water quality. A temporal variation correlated with the seasons (dry or rainy) is noted. Turbidity depends on the concentration of suspended solids (SS) in the water and drained particles and therefore on the seasons. Just like the temperature, the conductivity changes with the season. The waters of the Méné River are generally acidic. The results obtained show that there is a low level of pollution by chlorides, phosphates, nitrites and nitrates. A slight pollution of the waters of Méné in organic matter (chemical oxygen demand values are less than 25 mg∙L−1 during dry season and 32.33 ± 4.73 mg∙L−1 during rainy season) was observed. The concentrations of metallic trace elements such as iron, manganese and aluminum indicate significant pollution of these waters by these elements. Overall, the waters of the Méné River are of satisfactory quality because all the physicochemical parameters analyzed have values below standards during the dry season as well as during the rainy season with the exception of COD and a few metallic trace elements.

关键词： Méné Physicochemical Parameters River Season Water Quality

Hydrogeochemical Characterization of Groundwater from Fissured Aquifers in the Angovia Mine Operating Permit Area (Central-West Côte d’Ivoire)

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Journal of Water Resource and Protection 2024年第1期16卷 83-101页

作者： Kouadio Michel Yao Tanina Drissa Soro Tanoh Jean Jacques Koua Akaie Jean Fabrice Tchakray Yao emile Desmond Konan Brou Dibi Laboratory of Sciences and Technologies of Environment University Jean Lorougnon Guede Daloa C&ocircte d’Ivoire

The main objective of this study is to determine the hydrogeochemical specificities of the groundwater of the Angovia mine operating permit, located in the Yaouré mountains in the center-west of Côte d’Ivoire. To do so, descriptive and multivariate statistical analysis methods with the SOM (Self Organizing Maps) algorithm were applied to the physicochemical parameters of 17 boreholes using the calcite (ISC) and dolomite (ISD) saturation indices. The results obtained have shown that the groundwater in the Angovia mine operating permit area has an average temperature of 27.52°C (long rainy season) and 27.87°C (long dry season) and has an average pH of 7.09 ± 0.35 during the main rainy season and 7.32 ± 0.35 during the main dry season. They are mineralized with an average electrical conductivity of 505.98 ± 302.85 μS/cm during the long rainy season and with 450.33 ± 233.74 μS/cm as average during the long dry season. The main phenomena at the origin of groundwater mineralization are water residence time, oxidation-reduction and surface inflow. The study of the relative age of the water shows that the groundwater in the Angovia mine operating permit area is mainly undersaturated with respect to calcite and dolomite. They are therefore very old in the aquifer with a slow circulation speed during the long rainy season and the long dry season.

关键词： Hydrogeochemistry Mineralization Fissure Aquifers Operating Permits The Angovia Mine

Cost of Medical Treatment for Primary Open-Angle Glaucoma in Relation to Patients’ Income and Its Impact on the Prognosis of the Disease, in Bouaké University Hospital

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Open Journal of Ophthalmology 2024年第1期14卷 8-17页

作者： Yves Ouattara Liliane Ella Godé Zana Diabaté Franck Hermann Koffi Mamadou Korka Diallo Philippe emile France Koffi Bilé Diomandé François Gossé Ibrahim Abib Diomandé Ophthalmology Department of Bouaké University Hospital (CHU de Bouaké) Bouaké C&#244te d’Ivoire

Introduction: Medical treatment for POAG is continuous and lifelong treatment. The aim of this study was to evaluate the relationship between the cost of this treatment and patients’ income and the impact of this relationship on treatment compliance. Materials and Methods: Prospective cross-sectional study with a descriptive aim covering sociodemographic data, average incomes, and direct and indirect costs of treatment of 57 patients followed for POAG during the period from January 1, 2012, to December 31, 2016 (5 years). Results: The patients were aged 25 to 77 years (mean = 54.4 years) with a male predominance (sex ratio = 1.5). Retirees were the most represented (26.32%), followed by workers in the informal sector (14.04%) and housewives (12.28%). Patients who had an annual income less than or equal to 900,000 CFA francs (€1370.83) per year represented 56.14% and those who did not have health coverage represented 57.89%. The treatment was monotherapy (64.91%), dual therapy (31.58%) or triple therapy (3.05%) and the average ratio of “annual cost of treatment to annual income” was 0.56 with for maximum 2.23 and 0.02 as minimum. Patients who considered the cost of treatment unbearable for their income represented 78.95%. Conclusion: Prevention of blindness due to glaucoma requires early detection but also the establishment of health coverage mechanisms to improve compliance with medical treatment. In addition, consideration should be given to the development of glaucoma surgery in our country, the indication of which could be the first intention in certain patients, considering for those patients, the geographical and financial accessibility of medical treatment. .

关键词： Primary Open-Angle Glaucoma Treatment Cost Medical Treatment Income Blindness