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Colonic duplication in an adult who presented with chronic constipation attributed to hypothyroidism

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World Journal of Gastroenterology 2008年第4期14卷 644-646页

作者： Tihomir Kekez Goran Augustin Irena Hrstic Dubravko Smud Mate Majerovic Zeljko Jelincic emil Kinda Department of Surgery Division of Abdominal SurgeryClinical Hospital Center ZagrebKispaticeva 1210000 ZagrebCroatia Department of Internal medicine Division of GastroenterologyClinical Hospital Center ZagrebKispaticeva 1210000 ZagrebCroatia

Gastrointestinal duplications are an uncommon congenital abnormality that manifest before the age of two in 80% of cases. Ileal duplication is the most common while colonic duplication, either cystic or tubular, occurs in 10%-15% of cases and remains asymptomatic and undiagnosed in most cases. Mostly occurring in pediatric patients, colonic duplication is encountered in adults in only a few cases. The most common clinical manifestations are abdominal pain and intestinal obstruction. Rarely, duplications present with signs of acute abdomen or acute bleeding. This study reports a case of colonic duplication in an adult who presented with chronic constipation. Complete diagnostic workup was made on several occasions during the previous eight year period, but no pathology was found and chronic constipation was attributed to hypothyroidism caused by long standing Hashimoto thyroiditis. Nultislice CT, performed because of abdominal distension, defined colonic pathology but the definite diagnosis of duplication of the transversal colon was made at operation. The cystic duplication and the adjacent part of the ascending and transversal colon were excised enblock. This study implies that colonic duplication, though uncommon, should be included in the differential diagnosis of chronic constipation even when precipitating factors for constipation, such as hypothyroidism are present.

关键词： Colonic duplication Constipation Abdominaldistension Hypothyroidism

Cardiac papillary fibroelastoma

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Journal of Geriatric Cardiology 2021年第5期18卷 346-351页

作者： Dominika M Zoltowska Edin Sadic Kyeesha Becoats Shreya Ghetiya Aleem Azal Ali Srinivasan Sattiraju emil Missov Department of Cardiovascular Disease University of Florida College of MedicineJacksonvilleFLUSA

Papillary fibroelastoma(PFE)is a primary,histologically benign endocardial *** PFE has long been reported as the second most common primary cardiac neoplasm,it has since pulled ahead of cardiac myxomas,largely due to evolving cardiac imaging *** PFEs are benign histologically,they have the potential for devastating clinical consequences,transient ischemic attack,stroke,myocardial infarction,syncope,pulmonary,and peripheral *** increased detection rate,there remains uncertainty regarding etiology,exact prevalence,and clinical management of *** paucity of information is reflected by the lack of official guidelines on this *** this article,we aim to summarize the current state of understanding regarding PFE and discuss areas of ongoing controversy.

关键词： cardiac neoplasm clinical

Pressure drop of structured packing in pilot column and comparison to common correlations

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Chinese Journal of Chemical Engineering 2023年第12期64卷 281-291页

作者： emil Madsen Randi Neerup Arne Gladis Jens K.Jørsboe Nicolas von Solms Philip L.Fosbøl Center for Energy Resources Engineering(CERE) Department of Chemical and Biochemical EngineeringTechnical University of Denmark(DTU)Søltofts Plads 2292800 Kgs.LyngbyDenmark

Packed columns are widely used in the chemical industry such as absorption,stripping,distillation,and extraction in the production of *** chemicals,and *** loss and pressure drop correlations are of special interest when it comes to the hydrodynamic properties of a *** pressure loss across the column is of interest in the design phase when the size of the blower to drive the gas stream through the column has to be *** loading point and flooding point are also influenced by the pressure loss and the area of operation is determined from these *** work examines four different correlations on pressure *** correlations are(i)Ergun’s equation(1952),(ii)an improved version of Ergun’s equation by Stichlmair,Bravo,and Fair(1989),(iii)an equation developed by Billet and Schultes(1999),and(iv)an equation by Rocha,Bravo,and Fair(1993).The complexity of the correlations is increasing in the mentioned order,Ergun’s equation being the simplest *** study investigates if the more complicated correlations give better predictions to pressure drop in packed *** is determined by comparing the correlations to experimental data for pressure drop in a packed column with 8.2 m of structured packing using water as the liquid and atmospheric air as the *** experiments were carried out for determining the pressure drop in the column with liquid flows varying from 0 to 500 kg·h^(-1).At constant liquid flow,the gas flow was varied from approximately 10 to 70 kg·h^(-1).The pressure drop across the non-wetted column was best described by the correlation by Rocha et *** the pressure drop for liquid flows from 100 to 500 kg·h^(-1)was,in general,best described by Stichlmair’s *** an irrigated column,the highest deviation was a predicted pressure drop 69.6%lower than *** best prediction was 0.1%higher than the *** study shows,surprisingly,that for a system of water and atmospheric air,complica

关键词： Pressure drop correlations Packed columns Structured packing Fluid dynamics

Effects of primary selective laser trabeculoplasty on anterior segment parameters

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International Journal of Ophthalmology(English edition) 2015年第5期8卷 954-959页

作者： Suzan Guven Yilmaz Melis Palamar emil Yusifov Halil Ates Sait Egrilmez Ayse Yagci Department of Ophthalmology Faculty of MedicineEge University

AIMTo investigate the effects of selective laser trabeculoplasty (SLT) on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG).METHODSPentacam measurements of 45 eyes of 25 (15 females and 10 males) patients (12 with OHT, 13 with POAG) before and after SLT were obtained. Measurements were taken before and 1 and 3mo after SLT. Pentacam parameters were compared between OHT and POAG patients, and age groups (60y and older, and younger than 60y).RESULTSThe mean age of the patients was 57.8±13.9 (range 20-77y). Twelve patients (48%) were younger than 60y, while 13 patients (52%) were 60y and older. Measurements of pre-SLT and post-SLT 1mo were significantly different for the parameters of central corneal thickness (CCT) and anterior chamber volume (ACV) (P0.05).CONCLUSIONSLT leads to significant increase in CCT and decrease in ACV at the 1st month of the procedure. Effects of SLT on these anterior segment parameters, especially for CCT that interferes IOP measurement, should be considered to ensure accurate clinical interpretation.

关键词： anterior segment selective laser trabeculoplasty Pentacam

All carbon non-covalent exohedral hybrids:C60 aggregates on nanotube networks

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Journal of Energy Chemistry 2018年第4期27卷 957-961页

作者： Evgenee Yekymov Celine Bounioux Racheli Itzhak-Cohen Leila Zeiri emil Shahnazaryan Eugene A.Katz Rachel Yerushalmi-Rozen Department of Chemical Engineering the Ben-Curion University of the NegevBeer-ShevaIsrael The Ilse Katz Institute for Nanoscience and Technology the Ben-Gurion University of the NegevBeer-ShevaIsrael Department of Solar Energy and Envirornental Physics Jacob Blaustein Institute of Desert ResearchBen-Garion University of the NegevSde-Boker CampusMidreshet Ben-GurionIsrael

Exohedral van der Waals （vdW） hybrids comprising pristine carbon nanotubes （CNTs） and C60 fullerenes are expected to enable the engineering of carbonaceous materials with tunable physical and chemical properties due to the unperturbed sp2 hybridization of the comprising allotropes. In spite of theoretical predictions, experimental realization of exohedral non-covalent hybridization of unmodified C60 fullerenes and CNTs was not reported before, probably due to the relatively strong inter-fullerene and inter-tube interactions that drive the system toward phase separation and the formation of fullerene crystals and CNTs bundles. Here we describe a two-step process for preparation of C60-CNTs hybrids. The first step is based on solution-assembly of random, 3D-networks of individual, pristine CNTs followed by fast solvent-quenching. In the second step sublimated fullerenes are deposited onto the pre-assembled networks where structural defects serve as nucleation points for fullerite nanocrystals. Annealing at low temperature （80 ℃） results in re-organization of the C6o nanocrystals into nanometric layers, forming a CNT-C6o core-shell like cylindrical hybrids. Raman characterization and the observed high mobility of the fullerenes at the CNT surface support the assumption that the exohedral hybrids are of vdW type. The approach presented here offers a pathway for preparation of exohedral hybrids with controlled nano- morphology： CNTs-networks decorated by nanometric C60 crystals and CNTs-3D-networks coated by a shell of non-covalently bonded mono- or multi-layers of C60 molecules that may serve to shape the nanomorphology of the active layer in polymer-fullerene bulk-heterojunction solar cells.

关键词： Fullerenes Exohedral hybrids Carbon-nanotubes

Post-op cocaine use resulting in catastrophic cardiovascular compromise

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Journal of Geriatric Cardiology 2023年第2期20卷 155-158页

作者： Abhinav Karan Aleem Azal Ali Khadeeja Esmail Temitope Akinjogbin Sanjay Lamsal emil Missov Internal Medicine University of Florida College of Medicine-JacksonvilleFloridaUSA Division of Cardiology University of Florida College of Medicine-JacksonvilleFloridaUSA Department of Radiology University of Florida College of Medicine-JacksonvilleFloridaUSA

Cardiac tamponade can result from a variety of intrapericardial or extrapericardial sources of compression of the heart and great *** tamponade can be acute or subacute and results from fluid or gas collection in the pericardial space leading to impairment in cardiac *** cardiac tamponade following open heart surgery can be caused by hemorrhage within the pericardial sac or by mediastinal hematoma formation.

关键词： cardiac function acute

DelPhi Web Server:A Comprehensive Online Suite for Electrostatic Calculations of Biological Macromolecules and Their Complexes

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Communications in Computational Physics 2013年第1期13卷 269-284页

作者： Subhra Sarkar Shawn Witham Jie Zhang Maxim Zhenirovskyy Walter Rocchia emil Alexov Computational Biophysics and Bioinformatics Department of PhysicsClemson UniversityClemsonSC 29634USA Department of Computer Science Clemson UniversityClemsonSC 29634USA Drug Discovery and Development Italian Institute of Technologyvia Morego 3016163 GenovaItaly

Here we report a web server,the DelPhi web server,which utilizes DelPhi program to calculate electrostatic energies and the corresponding electrostatic potential and ionic distributions,and dielectric *** server provides extra services to fix structural defects,as missing atoms in the structural file and allows for generation of missing hydrogen *** hydrogen placement and the corresponding DelPhi calculations can be done with user selected force field parameters being either Charmm22,Amber98 or *** completion of the calculations,the user is given option to download fixed and protonated structural file,together with the parameter and Delphi output files for further *** Jmol viewer,the user can see the corresponding structural file,to manipulate it and to change the *** addition,if the potential map is requested to be calculated,the potential can be mapped onto the molecule *** DelPhi web server is available from http://***/delphi webserver.

关键词： DelPhi electrostatics proteins continuum models electrostatic potential finitedifference Poisson-Boltzmann solver

In Silico Investigation of pH-Dependence of Prolactin and Human Growth Hormone Binding to Human Prolactin Receptor

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Communications in Computational Physics 2013年第1期13卷 207-222页

作者： Lin Wang Shawn Witham Zhe Zhang Lin Li Michael Hodsdon emil Alexov Computational Biophysics and Bioinformatics Department of PhysicsClemson UniversityClemsonSC 29634USA Department of Laboratory Medicine and the Department of Pharmacology Yale School of MedicineNew HavenConnecticut 06520USA

Experimental data shows that the binding of human prolactin(hPRL)to human prolactin receptor(hPRLr-ECD)is strongly pH-dependent,while the binding of the same receptor to human growth hormone(hGH)is *** we carry in silico analysis of the molecular effects causing such a difference and reveal the role of individual amino *** is shown that the computational modeling correctly predicts experimentally determined pKa’s of histidine residues in an unbound state in the majority of the cases and the pH-dependence of the binding free *** analysis carried in conjunction with calculated pH-dependence of the binding revealed that the main reason for pH-dependence of the binding of hPRL-hPRLr-ECD is a number of salt-bridges across the interface of the complex,while no salt-bridges are formed in the ***,most of the salt-bridges involve histidine residues and this is the reason for the pH-dependence across a physiological range of *** analysis not only revealed the molecular mechanism of the pH-dependence of the hPRL-hPRLr-ECD,but also provided critical insight into the underlying physicchemical mechanism.

关键词： Human prolactin human prolactin receptor human growth hormone pKa calculations pH-dependence electrostatics

Challenges in Thermal Welding of Aluminium Alloys

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World Journal of Engineering and Technology 2018年第2期6卷 296-303页

作者： emil Schubert ABICOR Binzel Giessen Germany

Modern transport systems have the challenge to integrate more and more functions. This increases the weight of the structures. On the other hand demands and the legal regulations for emissions can only be fulfilled if the weight is reduced. This results in an ongoing increase of the usage of lightweight materials. Due to its low density and high strength Aluminium Alloys are the most used lightweight metals. However, some other physical properties hamper the processing of these alloys. The publication shows ways to overcome these challenges applying appropriate material preparation and handling in combination with specialized welding equipment for Aluminium welding. Application examples demonstrate the state of the art in Aluminium welding.

关键词： Aluminium Alloys Thermal Welding