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Mortality rate after total knee arthroplasty or total hip arthroplasty in patients with a history of liver transplant

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World Journal of Orthopedics 2024年第4期15卷 310-311页

作者： E carlos rodriguez-merchan Department of Orthopedic Surgery La Paz University Hospital-IdiPazMadrid 28046Spain

In this editorial I comment on the article by Ahmed et al published in a recent issue of the World J Orthop 2023;14:*** is well known that patients who have undergone a liver transplant(LT)may need to have a total hip arthroplasty(THA)or total knee arthroplasty(TKA)*** et al stated that the mortality rate in these patients was similar to the one of the general ***,there are three articles previously published that found higher mortality in LT patients who experienced THA/TKA than in the general population(individuals without LT).Therefore,in this Editorial I would like to point out that there is controversy in the literature regarding whether LT patients undergoing THA/TKA have higher mortality than the general ***,future research should attempt to resolve this controversy.

关键词： Liver transplant Total knee arthroplasty Total hip arthroplasty Results Mortality

Metastatic pancreatic and lung cancer patient in complete remission following immunotherapy: A case report and review of literature

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2233-2240页

作者： Joaquina Martínez-Galán Cristina Jiménez-Luna Isabel rodriguez Elisabeth Maza carlos García-Collado Antonio Rodríguez-Fernández Javier Luis López-Hidalgo Octavio Caba Department of Medical Oncology Virgen de las Nieves University HospitalGranada 18014Spain Instituto de Investigación Biosanitaria Ibs.GranadaGranada 18012Spain Institute of Biopathology and Regenerative Medicine(IBIMER) University of GranadaGranada 18016Spain Pharmacogenetics Unit Virgen de las Nieves University HospitalGranada 18014Spain Department of Medicina Nuclear Virgen de las Nieves University HospitalGranada 18014Spain Department of Anatomía Patológica Virgen de las Nieves University HospitalGranada 18014Spain

BACKGROUND Metastatic pancreatic ductal adenocarcinoma(PDAC)is a lethal malignancy with dispiriting survival *** is a promising approach to many cancer types,but achieves poor outcomes in advanced PDAC due to its immunosuppressive tumor *** describe a case of metastatic PDAC effectively treated with *** SUMMARY We report the case of a 67-year-old woman with unresectable locally advanced PDAC,treated with gemcitabine plus nab-paclitaxel followed by radiotherapy plus *** nine months,pancreatic tumor progression was observed at the level of the hepatic hilum with the appearance of a new pulmonary nodule suggestive of a second primary,confirmed by left lung *** immunotherapy was then initiated with pembrolizumab,an immune checkpoint inhibitor targeting programmed cell death protein-1 that covers the two tumor *** patient showed a complete metabolic response that was maintained throughout the *** patient continues to be disease-free at 5.6 years since the start of *** These results suggest that the administration of pembrolizumab after chemoradiotherapy has a beneficial effect in patients with metastatic *** our knowledge,this is the first reported case of a patient with metastatic PDAC and metastatic lung cancer showing such a long-lasting complete response after pembrolizumab treatment without curative *** studies are required to determine biomarkers that identify PDAC patients most likely to benefit from this immunotherapy.

关键词： Pancreatic ductal adenocarcinoma Lung cancer Immunotherapy Pembrolizumab Programmed cell death protein-1 Case report

Deforestation in Latin America in the 2000s predominantly occurred outside of typical mature forests

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The Innovation 2024年第3期5卷 88-98页

作者： Zhiyu Zhang Wenjian Ni Shaun Quegan Jingming Chen Peng Gong Luiz carlos Estraviz rodriguez Huadong Guo Jiancheng Shi Liangyun Liu Zengyuan Li Yating He Qinhuo Liu Yosio Shimabukuro Guoqing Sun Key Laboratory of Remote Sensing and Digital Earth Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Shijingshan DistrictBeijing 100049China Chinal of Mathematics and Statistics University of SheffieldSheffield S37RHUK Department of Geography and Program in Planning University of TorontoTorontoON M5S 3G3Canada Department of Earth Sciences and Department of Geography University of Hong KongHong KongChina Forest Science Department Luiz de Queiroz College of AgricultureUniversity of São PauloAv.Pádua Dias11Piracicaba 13418-900Brazil National Space Science Center Chinese Academy of SciencesBeijing 100190China Institute of Forest Resource Information Techniques Chinese Academy of ForestryBeijing 100091China Research Institute of Forest Policy and Information Chinese Academy of ForestryBeijing 100091China Remote Sensing Department National Institute for Space Research(INPE)Av.dos Astronautas 1758São Josédos Campos 12227-010Brazil Department of Geographical Sciences University of MarylandCollege ParkMD 20742USA

The role of tropical forests in the global carbon budget remains controversial,as carbon emissions from deforestation are highly *** high uncertainty arises from the use of either fixed forest carbon stock density or maps generated from satellite-based optical reflectance with limited sensitivity to biomass to generate accurate estimates of emissions from *** space missions aiming to accurately map the carbon stock density rely on direct measurements of the spatial structures of forests using lidar and *** found that lost forests are special cases,and their spatial structures can be directly measured by combining archived data acquired before and after deforestation by space missions principally aimed at measuring ***,using biomass mapping,we obtained new estimates of carbon loss from deforestation ahead of forthcoming space ***,using a high-resolution map of forest loss and the synergy of radar and lidar to estimate the aboveground biomass density of forests,we found that deforestation in the 2000s in Latin America,one of the severely deforested regions,mainly occurred in forests with a significantly lower carbon stock density than typical mature forests.

关键词： forest Latin lidar

Physical activity and amyloid beta in middle-aged and older adults:A systematic review and meta-analysis

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Journal of Sport and Health Science 2024年第2期13卷 133-144页

作者： María rodriguez-Ayllon Patricio Solis-Urra Cristina Arroyo-ávila Miriam álvarez-Ortega Pablo Molina-García Cristina Molina-Hidalgo Manuel Gómez-Río Belinda Brown Kirk I.Erickson Irene Esteban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and Social Sciences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Physical Medicine and Rehabilitation Service Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Psychology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia School of Medical and Health Sciences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health Research Institute Neuroscience Institute OrlandoOrlandoFL 32803USA Physiopathology of Obesity and Nutrition Research Center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels *** aimed to explore the relationship between physical activity and Aβin middle-aged and older ***:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,*** were eligible if they included physical activity and Aβdata in adults aged 45 years or ***-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβ***:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and *** physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older ***,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included *** observational studies,higher levels of physical activity were positively associated with Aβonly in ***,further research is needed t

关键词： Aging Cognitive impairment Dementia Exercise PET

Bridge plating in the setting of radiocarpal instability:Does distal fixation to the second or third metacarpal matter?A cadaveric study

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World Journal of Orthopedics 2023年第4期14卷 207-217页

作者： Eloy Tabeayo James M Saucedo Ramesh C Srinivasan Amita R Shah Efstathios Karamanos Jason Rockwood E carlos rodriguez-merchan Department of Orthopedic Surgery Albert Einstein College of MedicineMontefiore Medical CenterNew YorkNY 10461United States Houston Methodist Institute for Academic Medicine Houston Methodist Orthopedics and Sports MedicineHoustonTX 77479United States Hand Center of San Antonio and the Department of Orthopedic Surgery University of Texas Health Science CenterThe Hand Center of San AntonioSan AntonioTX 78240United States University of Texas Health Science Center at San Antonio University of North Carolina at Chapel HillSan AntonioTX 78229United States Surgeon in the Division of Acute Care Surgery in the Department of Surgery at Henry Ford Hospital in Detroit UT Health San AntonioSan AntonioTX 78229United States Naval Hospital Yokosuka Yokosuka96350-1600Japan Department of Orthopedic Surgery La Paz University Hospital-IdiPazMadrid 28046Spain

BACKGROUND Radiocarpal dislocations are rare but potentially devastating *** outcomes are associated with inadequate or lost reduction,such as ulnar translocation,but no consensus exists on the ideal fixation *** bridge plate fixation has been described for various settings in the treatment of complex distal radius fractures and can be fixed distally to the second or third metacarpal,but its application for radiocarpal dislocations has not been *** To determine whether distal fixation to the second or third metacarpal *** Using a cadaveric radiocarpal dislocation model,the effect of distal fixation was studied in two stages:(1)A pilot study that investigated the effect of distal fixation alone;and(2)a more refined study that investigated the effect of described techniques for distal and proximal *** were measured in various parameters to determine the quality of the reduction *** The pilot study found that focusing on distal fixation alone without changing proximal fixation results in ulnar translocation and volar subluxation when fixing distally to the second metacarpal compared with the *** second iteration demonstrated that anatomic alignment in coronal and sagittal planes could be achieved with each *** In a cadaveric radiocarpal dislocation model,anatomic alignment can be maintained with bridge plate fixation to the second metacarpal or the third metacarpal if the described technique is *** considering dorsal bridge plate fixation for radiocarpal dislocations,the surgeon is encouraged to understand the nuances of different fixation techniques and how implant design features may influence proximal placement.

关键词： Wrist Instability Bridge plate Dorsal spanning plate Radiocarpal dislocation model Cadaveric study

Gone with the wind： Seasonal trends in foraging movement directions for a central-place forager

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Current Zoology 2014年第5期60卷 604-615页

作者： Jesus HERNANDEZ-PLIEGO carlos rodriguez Javier BUSTAMANTE Department of Wetland Ecology Estacion Biologica de Dofiana CSIC c/Amorico Vespucio s/n 41092 Seville Spain Department of Conservation Biology Estacion Biologica de Dofiana C SIC c/Amorico Vespucio s/n 41092 Seville Spain

Lesser kestrels Falco naumanni are migratory central-place foragers that breed in dynamic arable landscapes. After arriving from migration, kestrels have no knowledge of the distribution of crops, and consequently prey, around their colony. The energy demand of pairs increases as breeding season progresses, but at the same time prey abundance, and their knowledge on prey distribution, also increases. Wind can have a strong influence on flight cost and kestrels should try to reduce energy expendi- ture when possible. When prey abundance is low, kestrels have little knowledge of prey distribution, and pairs have no chicks, they could reduce foraging flight cost by leaving the colony with tailwinds. When prey is abundant, knowledge on prey distribu- tion has increased, and chick demand is high, kestrels should fly to the most favorable foraging patches. We analyzed foraging trips directions in a lesser kestrel colony along the breeding season and in relation to wind speed and direction. We recorded 664 foraging trips from 19 individuals using GPS-dataloggers. We found that outward flights direction changed from uniform to a concentrated distribution along the season, as prey abundance and individual experience increased. We also found a temporal trend in the angular difference between outward flights and wind directions, with low values early in the season and then increa- sing as expected, but again low values at the end, contrary to expectation. Results suggest changes in kestrels foraging strategy along the season in relation to wind. Kestrels depart more with tailwinds in exploratory flights early in the season, while there is a spurious coincidence in direction to preferred foraging patches and dominant wind direction at the end [Current Zoology 60 （5）： 604-615, 2014].

关键词： Falco naumanni Movement ecology Foraging behavior Wind effect GPS-dataloggers

Photovoltaic-based DC microgrid with partial shading and fault tolerance

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Journal of Modern Power Systems and Clean Energy 2019年第2期7卷 340-349页

作者： carlos CORREA-BETANZO Hugo CALLEJA carlos AGUILAR Adolfo R.LOPEZ-NUNEZ Elías rodriguez Electronics Department National Center for Research and Development of Technology62490 CuernavacaMorelosMexico Electronics Department Technological Institute of Celaya38010 CelayaGuanajuatoMexico

Partial shading is a common problem that affects bus regulation in DC microgrids with several photovoltaic(PV) modules as energy sources, as a result of reduced solar irradiance reaching the *** problem can be mitigated by incorporating batteries, but if they are not included, appropriate control strategies must be used. This paper presents a new approach in a PV-based DC microgrid, which provides a high-quality bus voltage regulation in islanding mode, without being affected by partial shading or problems associated with PV module connection and disconnection. The solution proposed herein ensures a proper voltage regulation without being affected by problems such as failures in PV modules or mismatch between them. Besides, it can help to prevent PV partial shade stress by disconnecting the affected modules. A further advantage of the approach is the flexibility to connect more PV modules. The advantages of this approach were verified in a 200 W prototype.

关键词： Photovoltaic Microgrid Partial shading Fault Control strategy

Woody biochar potential for abandoned mine land restoration in the U.S.:a review

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Biochar 2021年第1期3卷 7-22页

作者： carlos rodriguez‑Franco Deborah S.Page‑Dumroese U.S.Department of Agriculture Forest ServiceWashington Office.Research and Development20114th StreetS.W.2 NWWashingtonDC 20250USA U.S.Department of Agriculture Forest ServiceRocky Mountain Research Station1221 S.MainMoscowID 83843USA

There are thousands of abandoned mine land(AML)sites in the *** need to be restored to reduce wind and water erosion,provide wildlife forage,shade streams,and improve *** created from woody biomass that would normally be burned in slash piles can be applied to soil to improve soil properties and is one method to restore AML soil productive *** this‘waste’biomass for biochar and reclamation activities will reduce wildfire risk,air pollution from burning,and particulates released from burning *** has the potential to improve water quality,bind heavy metals,or decrease toxic chemical concentrations,while improving soil health to establish sustainable plant cover,thereby preventing soil erosion,leaching,or other unintended,negative environmental *** forest residues to create biochar also helps reduce woody biomass and improves forest health and *** address concerns surrounding organic and inorganic contaminants on the biochar and how this might affect its’efficacy and provide valuable information to increase restoration activities on AMLs using biochar alone or in combination with other organic *** examples of AML biochar restoration sites initiated to evaluate short-and long-term above-and belowground ecosystem responses are presented.

关键词： Biochar Abandoned mine lands Restoration Woody biomass Heavy metals

Lid scrubbing with a gel combining natural extracts for dry eye treatment

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1053-1059页

作者： Blanca Diaz-Vega carlos rodriguez-Fabuel Sofia Vitores-Mate carlos Carpena-Torres Gran Visión Oftalmología Madrid 28026Spain e-Health Vision Department of OphthalmologyMadrid 28232Spain Gran Óptica Madrid Department of Dry EyeMadrid 28026Spain Ocupharm Research Group Department of Optometry and VisionFaculty of Optics and OptometryComplutense University of MadridMadrid 28037Spain

AIM:To evaluate the effect of lid scrubbing using a gel combining different natural extracts on ocular signs and symptoms of dry eye ***:A retrospective study was performed on 19 dry eye patients(51.1±16.0y).Non-invasive tear break-up time,tear meniscus height,meibomian gland loss,lipid layer thickness,conjunctival redness,corneal staining,ocular surface disease index(OSDI),and ocular pain intensity were measured before(baseline),1wk,and 2mo after lid scrubbing with a gel containing different natural extracts(okra extract,aloe vera leaf juice,hydrolysed soy protein,caffeine,citrus unshiu peel extract,and raspberry seed oil).RESULTS:Compared with the baseline,there was a statistically significant improvement in both first(P=0.048)and average(P=0.026)non-invasive tear break-up time 2mo after treatment,as well as in corneal staining(P=0.043,0.012),OSDI(P<0.001),and ocular pain intensity(P<0.001)after 1wk and *** addition,there was no correlation between ocular signs and ***:The lid scrubbing with a gel combining different natural extracts show beneficial effects on tear film stability,corneal damage,and ocular symptoms,which is the reason why this therapeutic procedure is proposed as an alternative for dry eye ***,it is not possible to attribute this beneficial effect solely to the presence of the natural extracts in the gel,primarily due to the absence of a negative control group.

关键词： lid hygiene natural extracts okra aloe vera soy dry eye