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Long-term results of Ahmed glaucoma valve implantation in Egyptian population

International Journal of Ophthalmology(English edition) 2018年第3期11卷 416-421页

作者： eman elhefney Tharwat Mokbel Waleed Abou Samra Hanem Kishk Tarek Mohsen Amr El-Kannishy Department of Ophthalmology Faculty of Medicine Mansoura University

AIM： To evaluate the long-term results and complications of Ahmed glaucoma valve （AGV） implantation in a cohort of Egyptian patients. METHODS： A retrospective study of 124 eyes of 99 patients with refractory glaucoma who underwent AGV implantation and had a minimum follow-up of 5y was performed. All patients underwent complete ophthalmic examination and intraocular pressure （lOP） measurement before surgery and at ld, weekly for the 1st month, 3, 6mo, and ly after surgery and yearly afterward for 5y. lOP was measured by Goldmann applanation tonometry and/or Tono-Pen. Complications and the number of anti-glaucoma medications needed were recorded. Success was defined as lOP less than 21 mm Hg with or without anti-glaucoma medication and without additional glaucoma surgery. RESULTS： Mean age was 23.1±19.9y. All eyes had at least one prior glaucoma surgery, lOP was reduced from a mean of 37.2±6.8 to 19.2±5.2 mm Hg after 5y follow-up with a reduced number of medications from 2.64±0.59 to 1.81±0.4. Complete and qualified success rates were 31.5% and 46.0% respectively at the end of follow-up. The most common complications were encapsulated cyst formation in 51 eyes （41.1%）, complicated cataract in 9 eyes （7.25%）, recessed tube in 8 eyes （6.45%）, tube exposure in 6 eyes （4.8%） and corneal touch in 6 eyes （4.8%）. Other complications included extruded AGV, endophthalmitis and persistent hypotony. Each of them was recorded in only 2 eyes （1.6%）. ~ CONCLUSION： Although refractory glaucoma is a difficult problem to manage, AGV is effective and relatively safe procedure in treating refractory glaucoma in Egyptian patients with long-term follow-up. Encapsulated cyst formation was the most common complication, which limits successful lOP control after AGV implantation. However, effective complications management can improve the rate of success.

关键词： intraocular pressure Ahmed glaucoma valve refractory glaucoma long-term follow-up of glaucoma Ahmedvalve complications

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Efficacy of topical dorzolamide 2% in diabetic cystoid macular edema

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International Journal of Ophthalmology(English edition) 2021年第9期14卷 1413-1418页

作者： Amani E Badawi Tharwat H.Mokbel eman M elhefney Sherein M.Hagras Ameera G Abdelhameed Department of Ophthalmology Mansoura Ophthalmic CenterFaculty of MedicineMansoura UniversityMansoura 35516Egypt

AIM:To study the effect of topical dorzolamide 2%on macular thickness reduction in diabetic cystoid macular edema(CME).METHODS:This was a prospective,non-randomized,open study including eyes with diabetic macular edema(DME).All eyes received topical dorzolamide 2%three times daily for one *** in best-corrected visual acuity(BCVA),and central macular thickness(CMT)by optical coherence tomography were evaluated at 1 wk,1,and 3 mo ***:Ninety-three eyes(84 patients)were ***±SD(log MAR)BCVA improved significantly from 1.08±0.26 pretreatment to 0.66±0.24 at 1 mo and 0.87±0.26 at 3 mo post-treatment(P<0.001 both).The mean±SD CMT was significantly reduced from 535.27±97.4μm at baseline to 357.43±125.8μm at 1 mo and 376.23±114.5μm at 3 mo post-treatment(P<0.001 both).No significant ocular or systemic side effects were ***:Topical dorzolamide 2%results in significant improvement of mean BCVA and reduction of mean CMT at 3 mo *** can be used as an effective,affordable,and safe therapy for treatment of nonrefractory diabetic CME.

关键词： cystoid macular edema diabetic maculopathy dorzolamide retina

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