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Each coin has 2 sides: a positive role of alien Potamopyrgus antipodarum (Grey, 1843) snails in reducing the infection of native lymnaeids with trematodes

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Current Zoology 2024年第2期70卷 262-269页

作者： Anna Cichy Anna Stanicka elzbieta Zbikowska Faculty of Biological and Veterinary Sciences Nicolaus Copernicus University in TorunLwowska 187-100 TorunPoland

The change in the distribution of organisms in freshwater ecosystems due to natural or manmade processes raises the question of the impact of alien species on local *** most studies indicate a negative effect,the positive one is more difficult to discern,espe-cially in multispecies systems,including hosts and *** purpose of the study was to check whether the presence of an alien host,Potamopyrgus antipodarum,reduces the intensity of Echinoparyphium aconiatum metacercariae in a native host,Radix *** additionally tested the impact of water temperature and the biomass of the alien host on the dilution *** experimentally studied(1)the lifespan of echinostome cercariae in different temperatures,(2)the infectivity of cercariae toward the alien host and native host,and(3)the impact of different biomass of the alien host on the intensity of metacercariae in the native *** found that cercarial survival and infectivity were tem-perature ***,cercarial survival decreased with increasing temperature,contrary to cercarial *** cercariae entered the renal cavity of both the native host and alien host,and successfully transformed into *** number of metacercariae in the native host decreased with the increasing biomass of the alien *** results indicate that lymnaeids may benefit from the co-occur-rence with P antipodarum,as the presence of additional hosts of different origins may reduce the prevalence of parasites in native ***,the scale of the dilution effect depends not only on the increased spectrum of susceptible hosts but also on the other variables of the environment,including water temperature and host density.

关键词： biological invasion density dilution effect echinostomes Radix spp. temperature.

Revisiting the standards of cancer detection and therapy alongside their comparison to modern methods

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World Journal of Methodology 2024年第2期14卷 17-37页

作者： Piotr Gromek Zuzanna Senkowska elzbieta Pluciennik Zbigniew Pasieka Lin-Yong Zhao Adrianna Gielecinska Mateusz Kciuk Karol Klosinski Zaneta Kaluzinska-Kolat Damian Kolat Department of Functional Genomics Medical University of LodzLodz 90-752LodzkiePoland Department of Biomedicine and Experimental Surgery Medical University of LodzLodz 90-136LodzkiePoland Department of General Surgery&Laboratory of Gastric Cancer State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Gastric Cancer Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Molecular Biotechnology and Genetics University of LodzLodz 90-237LodzkiePoland Doctoral School of Exact and Natural Sciences University of LodzLodz 90-237LodzkiePoland

In accordance with the World Health Organization data,cancer remains at the forefront of fatal *** upward trend in cancer incidence and mortality has been observed globally,emphasizing that efforts in developing detection and treatment methods should *** diagnostic path typically begins with learning the medical history of a patient;this is followed by basic blood tests and imaging tests to indicate where cancer may be located to schedule a needle *** initiation of diagnosis is crucial since delayed cancer detection entails higher costs of treatment and ***,there is a need for novel cancer detection methods such as liquid biopsy,elastography,synthetic biosensors,fluorescence imaging,and reflectance confocal *** therapeutic methods,although still common in clinical practice,pose many limitations and are ***,there is a dynamic advancement of clinical research and the development of more precise and effective methods such as oncolytic virotherapy,exosome-based therapy,nanotechnology,dendritic cells,chimeric antigen receptors,immune checkpoint inhibitors,natural product-based therapy,tumor-treating fields,and photodynamic *** present paper compares available data on conventional and modern methods of cancer detection and therapy to facilitate an understanding of this rapidly advancing field and its future *** evidenced,modern methods are not without drawbacks;there is still a need to develop new detection strategies and therapeutic approaches to improve sensitivity,specificity,safety,and ***,an appropriate route has been taken,as confirmed by the approval of some modern methods by the Food and Drug Administration.

关键词： Cancer detection Liquid biopsy Synthetic biosensors Fluorescence imaging Reflectance confocal microscopy Elastography Cancer therapy Tumor-treating fields Oncolytic virotherapy Nanotechnology

Acyclic colorings of graphs with bounded degree

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Science China Mathematics 2016年第7期59卷 1427-1440页

作者： FIEDOROWICZ Anna SIDOROWICZ elzbieta Faculty of Mathematics Computer Science and Econometrics University of Zielona Góra

A k coloring(not necessarily proper) of vertices of a graph is called acyclic, if for every pair of distinct colors i and j the subgraph induced by the edges whose endpoints have colors i and j is acyclic. We consider some generalized acyclic k colorings, namely, we require that each color class induces an acyclic or bounded degree graph. Mainly we focus on graphs with maximum degree 5. We prove that any such graph has an acyclic 5 coloring such that each color class induces an acyclic graph with maximum degree at most 4. We prove that the problem of deciding whether a graph G has an acyclic 2 coloring in which each color class induces a graph with maximum degree at most 3 is NP complete, even for graphs with maximum degree 5. We also give a linear time algorithm for an acyclic t improper coloring of any graph with maximum degree d assuming that the number of colors is large enough.

关键词： acyclic coloring bounded degree graph computational complexity

Hybrid aqueous capacitors with improved energy/power performance

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Progress in Natural Science:Materials International 2015年第6期25卷 642-649页

作者： Jakub Menzel Krzysztof Fic elzbieta Frackowiak Poznan University of Technology Institute of Chemistry and Technical Electrochemistry

This work reports on a high-voltage,hybrid capacitor involving two separate redox *** solutions of Mg(NO3)2and KI have been used for negative and positive electrode,*** p H ? 2 for electrode( t) with KI solution and modifying Mg(NO3)2solution to p H ? 9 for negative side play a crucial role for a stable long-term operation of capacitor at enhanced voltage.A benefit from such a construction is a pseudocapacitive contribution from hydrogen sorption reaction on the negative electrode and high iodine/iodide activity on the positive electrode,enhancing the energy with no remarkable impact on the power *** solution allows a high voltage(1.8 V) to be reached and thereby high power and energy performance( 20 W h/kg at 1 k W/kg) to be *** long-term stability has been confirmed by floating and galvanostatic tests.

关键词： Electrochemical capacitors High-voltage systems Hybrid systems Carbon electrodes Aqueous systems Neutral electrolytes

Acyclic improper colouring of graphs with maximum degree 4

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Science China Mathematics 2014年第12期57卷 2485-2494页

作者： FIEDOROWICZ Anna SIDOROWICZ elzbieta Faculty of Mathematics Computer Science and Econometrics University of Zielona G'ora

A k-colouring （not necessarily proper） of vertices of a graph is called acyclic, if for every pair of distinct colours i and j the subgraph induced by the edges whose endpoints have colours i and j is acyclic. We consider acyclie k-eolourings such that each colour class induces a graph with a given （hereditary） property. In particular, we consider aeyclic k-eolourings in which each colour class induces a graph with maximum degree at most t, which are referred to as acyclic t-improper k-colourings. The acyelic t-improper chromatic number of a graph G is the smallest k for which there exists an acyclic t-improper k-colouring of G. We focus on acyclic colourings of graphs with maximum degree 4. We prove that 3 is an upper bound for the acyclic 3-improper chromatic number of this class of graphs. We also provide a non-trivial family of graphs with maximum degree 4 whose acyclic 3-improper chromatic number is at most 2, namely, the graphs with maximum average degree at most 3. Finally, we prove that any graph G with A（G） ≤ 4 can be acyelically coloured with 4 colours in such a way that each colour class induces an acyclic graph with maximum degree at most 3.

关键词： acyclic colouring acyclic improper colouring bounded degree graph hereditary property

Diagnostic accuracy of serum biochemical fibrosis markers in children with chronic hepatitis B evaluated by receiver operating characteristics analysis

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World Journal of Gastroenterology 2005年第45期11卷 7192-7196页

作者： Dariusz Marek Lebensztejn elzbieta Skiba Jolanta Tobolczyk Maria elzbieta Sobaniec-Lotowska Maciej Kaczmarski Ⅲrd Department of Pediatrics Department of Children Allergology Department of Clinical Pathomorphology

METHODS： We determined the serum level of apolipoprotein A-I （APO A-I）, haptoglobin （HPT） and a-2 macroglobulin （A2I） with an automatic nephelometer in 63 children （age range 4-17 years, mean 10 years） with biopsy-verified chronic HBeAg-positive hepatitis B. Fibrosis stage and inflammation grade were assessed in a blinded fashion according to Batts and Ludwig. We defined mild liver fibrosis as a score ≤2 and advanced fibrosis as a score equal to 3. ROC analysis was used to calculate the power of the assays to detect advanced liver fibrosis （AccuROC, Canada）. RESULTS： Serum concentrations of APO A-I, HPT and A2M were not significantly different in patients with chronic hepatitis B compared to controls. However, APO A-I level of 1.19 ng/L had a sensitivity of 85.7% and a specificity of 60.7% （AUC = 0.7117, P = 0.035） to predict advanced fibrosis. All other serum biochemical markers and their combination did not allow a useful prediction. None of these markers was a good predictor of histologic inflammation. CONCLUSION： Apolipoprotein A-I may be a suitable serum marker to predict advanced liver fibrosis in children with chronic hepatitis B.

关键词： Chronic hepatitis B Liver fibrosis Children Apolipoprotein A-I Haptoglobin a-2 macroglobulin

Carbon/carbon supercapacitors

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Journal of Energy Chemistry 2013年第2期22卷 226-240页

作者： elzbieta Frackowiak Qamar Abbas Franois Bguin Institute of Chemistry and Technical Electrochemistry Poznan University of Technology Piotrowo 3 60-965 Poznan Poland

Supercapacitors, or electrochemical capacitors, are a power storage system applied for harvesting energy and delivering pulses during short periods of time. The commercially available technology is based on charging an electrical double-layer （EDL）, and using high surface area carbon electrodes in an organic electrolyte. This review first presents the state-of-the-art on EDL capacitors, with the objective to better understand their operating principles and to improve their performance. In particular, it is shown that capacitance might be enhanced for carbons having subnanometric pores where ions of the electrolyte are distorted and partly desolvated. Then, strategies tbr using environment l^endly aqueous electrolytes are presented. In this case, the capacitance can be enhanced through pseudo-faradaic contributions involving i） surface functional groups on carbons, ii） hydrogen electrosorption, and iii） redox reactions at the electrode/electrolyte interface. The most promising system is based on the use of aqueous alkali sulfate as electrolyte allowing voltages as high as 2 V to be reached, due to the high overpotential for di-hydrogen evolution at the negative electrode.

关键词： supercapacitors electrochemical capacitors porous carbons electrolytes pore size pseudocapacitance

Relationships between serum lipid,lipoprotein,triglyceride-rich lipoprotein,and high-density lipoprotein particle concentrations in post-renal transplant patients

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第4期11卷 249-257页

作者： elzbieta KIMAK Magdalena HALABI Iwona BARANOWICZ-GASZCZYK Department of Laboratory Diagnostics Medical University of Lublinul. Chod■ki 120-093 LublinPoland Department of Nephrology Medical University of LublinJaczewskiego 820-093 LublinPoland

Objective:Disturbances in lipid and lipoprotein profiles in patients after kidney transplantation (Tx) are still not understood. Methods:Serum levels of lipids,lipoprotein,triglyceride-rich lipoproteins (TRLs),and high-density lipoprotein (HDL) particles were determined,lipid and lipoprotein ratios were calculated,and their relationships in Tx patients with hypertriglyceridemia (HTG) and lower apolipoprotein AI (apoAI) concentration were examined. Serum lipid and lipoprotein levels were measured in 109 Tx patients and 89 healthy subjects. HDL particle levels were de-termined by enzyme-linked immunosorbent assay (ELISA). Results:Tx patients had disturbed concentration,com-position,and metabolism of TRLs and HDL particles. Multivariance analysis showed significant and positive correlation between HDL cholesterol/apoAI (HDL-C/apoAI) and HDL-C/HDL ratios,which indicates that both ratios could sensi-tively reflect changes in the HDL subclasses and their distribution into smaller size particles. In Tx patients,the de-creased HDL-C/apoAI ratio indicates that,along with the decreased apoAI concentration,the HDL-C level is de-creased. However,a low HDL-C/HDL ratio indicates that HDL particles in Tx patients transport lesser content of HDL-C but more triglyceride (TG) (high TG/HDL ratio),and thus are hypercatabolized and removed; therefore,con-centration of HDL particles in serum was decreased. Conclusion:The decrease of HDL-C/apoAI ratio seems to be a good marker of HDL subclass distribution into smaller size particles.

关键词： Lipid Lipoprotein High-density lipoprotein particle Triglyceride-rich lipoprotein Renal transplantation

Phenotypic plasticity can explain evolution of sympatric polymorphism in the hairy snail Trochulus hispidus （Linnaeus, 1758）

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Current Zoology 2017年第4期63卷 389-402页

作者： Matgorzata PROCKOW elzbieta KUZNIK-KOWALSKA Pawet MACKIEWICZ Museum of Natural History University of Wroctaw Invertebrate Systematics and Ecology Institute of Sienkiewicza 21 50-335 WrocTaw Poland Department of Biology Wroctaw University of Environmental and Life Sciences Kozuchowska 5b 51-631 Wroctaw Poland Department of Genomics Faculty of Biotechnology University of Wroctaw Fryderyka Joliot-Curie 14a 50-383 Wroctaw Poland

Morphological variation of snails from the genus Trochulus is so huge that their taxonomy is unclear. The greatest variability concerns forms hispidus and sericeus/plebeius, which are often considered as separate species. To evidence the species barriers, we carried out crossbreeding ex- periments between these two sympatric morphs. Moreover, we compared the shell morphology of laboratory-bred offspring with their wild parents to test if the variation can be explained by the phenotypic plasticity model. We found that the two Trochulus morphs show no reproductive bar- riers. The fecundity rates, the mean clutch size, and F~ viability observed for all crosses were not significantly different. In hybrid crosses （in F2 generation）, we also recorded reproduction compati- bility, similar fecundity, and hatching success as in their parents. Accordingly, phylogenetic ana- lyses revealed the significant grouping of sequences from these different morphs and supported no constrains in reproduction between them. Comparison of shell morphology between wild and laboratory samples showed that various characters appeared highly plastic. The average shell shape of the hispidus morph changed significantly from flat with wide umbilicus to elevated with narrower umbilicus such as in the sericeus/plebeius morph. All these findings indicate that the examined morphs do not represent separate biological species and the evolutionary process is not advanced enough to separate their genetic pool. Therefore, phenotypic plasticity has played a sig- nificant role in the evolution of Trochulus shell polymorphism. The two morphs can evolve inde- pendently in separate phylogenetic lineages under the influence of local environmental conditions.

关键词： crossbreeding cytochrome c oxidase subunit I molecular phylogeny phenotypic variation principal component analysis shell morphology.