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Formation, Structure and Properties of Bulk Metallic Glasses

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Journal of Materials Science & Technology 1999年第2期15卷 97-110页

作者： Y. Li(Department of Materials Science, Faculty of Science, National University of Singapore, lower Kent Ridge Road,Singapore 119260 e-mail:masliy@nus.edu.sg) Department of Materials Science Faculty of Science National University of Singapore Singapore 119260 Lower Kent Ridge Road Singapore

Bulk metallic glasses with up to 72 mm critical section thickness have been obtained by conventional casting techniques and the properties of these materials, particularly the mechanical and magnetic properties have been studied. These materials have been demonstrated to have novel properties which are fundamentally different from their crystalline counterparts. The recent status of research and development in formation, structure and properties of bulk metallic glasses is reviewed. The techniques to produce such bulk glasses are summarized and the glass forming ability and the critical cooling rate of these materials are discussed. Further consideration of the development and application of this new class of materiaIs will be proposed.

关键词： Ni Zr Structure and Properties of Bulk Metallic Glasses Formation OK Cu Figure

enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

An anisotropic propagation technique for synthesizing hyperbranched polyvillic gold nanoparticles

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Nano Research 2016年第10期9卷 2889-2903页

作者： Aaron S. Schwartz-Duval Santosh K. Misra Prabuddha Mukhejee elyse Johnson Alvin S. Acerbo Dipanjan Pan Department of Bioengineering and Beckman Institute University of Illinois Urbana-Champaign Urbana 61801 USA Biomedical Research Center Carle Foundation Hospital Urbana 61801 USA Cytoviva Inc. Auburn 36830 USA Center for Advanced Radiation Sources The University of Chicago Chicago 60637 USA

Of late, many synthesis processes have been studied to develop irregular nano-rnorphologies of gold nanostructures for biomedical applications in order to increase the efficacy of nanoparticle theranostics, tune the plasmonic absorbance spectra, and increase the sensitivity of biomolecule detection through surface enhanced Raman spectroscopy. Here we report, a novel, non-seed mediated versatile single pot synthesis method capable of producing hyperbranched gold ＂nano-polyvilli＂ with more than 50-90 branching nanowires propagating from a single origin within each structure. The technique was capable of achieving precise tuning of the branch propagation where the branching could be controlled by varying the duration of incubation, temperature, and hydrogen ion concentration.

关键词： gold nanoparticles surface enhanced Raman spectroscopy (SeRS) anisotropy asymmetric nanocrystallization

Power Lunches on Financial Street

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China International Business 2008年第3期 56-57页

作者： elyse RIBBONS

Over the past few years, Beijing＇s business community has embarked on a gradual migration *** was when most multinational organizations were based in the east of the city, near Guomao, Jianguomen, or the east Third Ring Road. But, with the development of Beijing＇s new financial center, Financial Street, more and more businesses are relocating to the dusty delights of the West Second Ring Road.

关键词：北京金融中心餐馆餐饮业

Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(english edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAeI H.GHANDVAR e.JUMAeV S.KHATIR T.CUONG-Le School of Mechanical engineering Babol Noshirvani University of Technology Department of Mechanical engineering Faculty of Engineering New Uzbekistan University University of Business and Science Center for engineering Application and Technology Solutions Ho Chi Minh City Open University

This paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. The strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. The curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. Subsequently, the natural frequencies and transient response of the system are determined. The accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANSYS, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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Optimization of Multi-Join Queries in Shared-Nothing Systems

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Journal of Computer Science & Technology 1995年第2期10卷 149-162页

作者： Kian-Lee Tan(Department of Information Systems and Computer Science, National University ofSingapore, lower Kent Ridge Road, Singapore 0511) Department of Information Systems and Computer Science National University of Singapore Singapore

This paper proposes a semi-greedy framework for optimizing multi-joinqueries in shared-nothing systems. The plan generated by the framework com-prises several pipelines, each performing several joins. The framework deter-mines the 'optimal' number of joins to be performed in each pipeline. Thedecisions are made based on the cost estimation of the entire processing *** ekisting optimization algorithms are extended under the framework. Ananalytical model is presented and used to compare the quality of plans producedby each optimization algorithm. Our study shows that the new algorithms out-perform their counterparts that are not extended.

关键词： Multi-join optimization shared-nothing systems pipelining,hash join segmented right-deep tree

Translational Semantics for a Conceptual Level Query Language

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Journal of Computer Science & Technology 1995年第2期10卷 175-187页

作者： $Hock C. Chan(Department of Information Systems and Computer Science, National University ofSingapore, lower Kent Ridge Road, Singapore 0511) Department of Information Systems and Computer Science National University of Singapore Singapore

A conceptual level database language for the entity relationship (eR) modelimplicitly contains integrities basic to eR concepts and special retrieval seman-tics for inheritances of attributes and relationships. Prolog, which belongs tothe logical and physical level, cannot be used as a foundation to directly definethe database language. It is shown how Prolog can be enhanced to under-stand the concepts of entities, relationships, attributes and is-a *** enhanced Prolog is then used as a foundation to define the semantics of adatabase query language for the eR model. The three basic functions of modelspecification, updates and retrievas are defined.

关键词： Conceptual level query language semantics logic entityrelationship model abstraction level eR calculus

Oestrogen-androgen crosstalk in the pathophysiology oferectile dysfunction

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Asian Journal of Andrology 2003年第4期5卷 307-313页

作者： B Srilatha PG Adaikan Department of Obstetrics & Gynaecology National University of Singapore 5 lower Kent Ridge Road Singapore 119074Department of Obstetrics & Gynaecology National University of Singapore 5 Lower Kent Ridge Road Singapore 119074

Ageing in man is associated with a decline in testosterone following changes in the hypothalamo-pituitary testicular axis. This may offset the physiologic equilibrium between oestrogen and androgen and at some point when the ratio of free testosterone to oestradiol reaches a critical level, the oestrogenic gonadotropin suppressive effect predominates with decreased release of FSH and LH. Adding to this endocrinal complexity is the continued peripheral conversion to oestradiol through aromatisation. Although the androgen deficiency is not the sole cause for impotence in the elderly, there is a gradual decrease in nocturnal penile tumescence (NPT) and spontaneous morning erections with ageing. Despite the age related increase in oestrogen levels, the information on the pathophysiological role of the 'female hormone' in erectile dysfunction has been scanty. Together with our identification of oestrogen receptors within the penile cavernosum, we have delineated dysfunctional changes on male erection mediated by oestradiol. These findings parallel the recent concerns over environmental oestrogens on fertility declines in young men. Oestrogenic activity is also present in plants and thereby in human diet. These phytoestrogens are structurally and functionally similar to oestradiol and more potent than the environmental oestrogenic chemicals such as organochlorine and phenolic compounds. Thus in the light of growing concerns of possible compromising effects on sexuality by endogenous and environmental oestrogens, we are faced with the scientific need to delineate their role on the mechanism of male erectile pathway in health and disease for clinical correlates and prognostics.

关键词： oestrogen environmental oestrogens oestrogen receptor testosterone functional crosstalk erectile dysfunction