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Twitter Sentiment at the Hospital and Patient Level as a Measure of Pediatric Patient Experience

Open Journal of Pediatrics 2021年第4期11卷 706-722页

作者： Samantha Robinson ellie vicha Department of Mathematical Sciences University of Arkansas Fayetteville USA Department of Biological Sciences University of Arkansas Fayetteville USA

Although pediatric cancer survival rates have improved, cancer is still the leading cause of death by disease among children in the United States. With nearly 16,000 new diagnoses each year of children having an average age of six years old, there is still much to be done to improve survival rates among children diagnosed with cancer. Additionally, clinical outcomes can be greatly improved by first understanding the patient perspective and, consequently, there is a need to understand the pediatric cancer patient experience. Interest in the analysis of patient-reported outcome (PRO) measures, including those specific to patient experience, has grown in recent years as attempts are made to understand and assess latent (i.e., unobserved) traits such as quality of life. While most traditional PRO measures involve lengthy and costly surveys that are limited in scope, posts on social media platforms are frequently lauded as more authentic, unbiased measures of patient experience. While many previous studies have utilized Twitter as a source for patient experience data that is not easily captured by traditional PROs, very few studies have examined the use of Twitter data to explore and better understand the experience of pediatric cancer patients specifically. Lexicon-based sentiment analysis of Twitter data was used both to examine the pediatric cancer patient experience as well as to compare the attitudes, perceptions, and overall impressions of individuals with St. Jude experiences to those with more general experiences. Results indicated that patients reflected on their care with more relative negativity when speaking of experiences other than St. Jude. While there were some notable differences between the two comparison groups, the sentiment of both was still mostly positive. Pediatric oncology differs greatly from adult oncological care and, thus, the proposed use of sentiment

关键词： Twitter Health Data Acquisition Patient Experience Self-Report Measures Cancer

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The Impact of Short Selling Disclosure Regulatory Constraint on the Lending Market and Stock Ownership

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Journal of Modern Accounting and Auditing 2024年第3期20卷 99-114页

作者： Geoffrey Ducournau Jinliang Li Yan Li Zigan Wang Qie ellie Yin Tsinghua University BeijingChina The University of Hong Kong Hong KongChina Tsinghua University ShenzhenChina Hong Kong Baptist University Hong KongChina

We examine the impact of the short sell disclosure(SSD)regime on the stock lending market and investor behaviors,employing a staggered difference-indifference(DiD)*** research reveals that the introduction of the disclosure regime enhances market transparency,resulting in a diminished appeal of stock ownership in the lending market for active *** shift is accompanied by a reduction in information leakage risks and longer loan ***,our analysis reveals a significant decrease in the risk of loan recall by 4.87%,accompanied by an average increase of 23.72%in loan duration for short selling ***,the cost associated with short-sell disclosure causes a decline in both lending supply and short demand.

关键词： short sell disclosure stock equity lending market stock ownership

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Topology and Shape Optimization of 2-D and 3-D Micro-ArchitecturedThermoelastic Metamaterials Using a Parametric Level Set Method

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Computer Modeling in Engineering & Sciences 2021年第6期127卷 819-854页

作者： ellie Vineyard Xin-Lin Gao PepsiCo R&D Center ValhallaNY 10595USA Department of Mechanical Engineering Southern Methodist UniversityDallasTX 75275-0337USA

2-D and 3-D micro-architectured multiphase thermoelastic metamaterials are designed and analyzed using a parametric level set method for topology optimization and the finite element *** asymptotic homogenization approach is employed to obtain the effective thermoelastic properties of the multiphase ***ε-constraint multi-objective optimization method is adopted in the *** coefficient of thermal expansion(CTE)and Poisson’s ratio(PR)are chosen as two objective functions,with the CTE optimized and the PR treated as a *** optimization problems are solved by using the method of moving *** isotropic and anisotropic CTEs and stiffness constants are obtained for the topologically optimized metamaterials with prescribed values of PR under the constraints of specified effective bulk modulus,volume fractions and material *** solid materials along with one additional void phase are involved in each of the 2-D and 3-D optimal design *** numerical results reveal that the newly proposed approach can integrate shape and topology optimizations and lead to optimal microstructures with distinct topological *** current method can topologically optimize metamaterials with a positive,negative or zero CTE and a positive,negative or zero Poisson’s ratio.

关键词： Topology optimization thermoelastic metamaterial level set method sensitivity analysis Poisson’s ratio coefficient of thermal expansion effective elastic properties

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RGK regulation of voltage-gated calcium channels

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Science China(Life Sciences) 2015年第1期58卷 28-38页

作者： BURAEI Zafir LUMEN ellie KAUR Sukhjinder YANG Jian Department of Biology Pace University Ion Channel Research and Drug Development Center and Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan ProvinceKunming Institute of ZoologyChinese Academy of Sciences Department of Biological Sciences Columbia University

Voltage-gated calcium channels(VGCCs) play critical roles in cardiac and skeletal muscle contractions,hormone and neurotransmitter release,as well as slower processes such as cell proliferation,differentiation,migration and *** in VGCCs lead to numerous cardiac,muscle and neurological disease,and their physiological function is tightly regulated by kinases,phosphatases,G-proteins,calmodulin and many other *** years ago,RGK proteins were discovered as the most potent endogenous regulators of *** are a family of monomeric GTPases(Rad,Rem,Rem2,and Gem/Kir),in the superfamily of Ras GTPases,and they have two known functions: regulation of cytoskeletal dynamics including dendritic arborization and inhibition of *** we review the mechanisms and molecular determinants of RGK-mediated VGCC inhibition,the physiological impact of this inhibition,and recent evidence linking the two known RGK functions.

关键词： calcium channel modulation trafficking cardiac physiology neurobiology beta subunit

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New perspectives on epigenetic modifications and PARP inhibitor resistance in HR-deficient cancers

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Cancer Drug Resistance 2023年第1期6卷 35-44页

作者： Rachel Bayley ellie Sweatman Martin R.Higgs Institute of Cancer and Genomic Sciences University of BirminghamBirmingham B152TTUK

The clinical treatment of DNA-repair defective tumours has been revolutionised by the use of poly(ADP)ribose polymerase(PARP)***,the efficacy of these compounds is hampered by resistance,which is attributed to numerous mechanisms including rewiring of the DNA damage response to favour pathways that repair PARP inhibitor-mediated ***,we comment on recent findings by our group identifying the lysine methyltransferase SETD1A as a novel factor that conveys PARPi *** discuss the implications,with a particular focus on epigenetic modifications and H3K4 *** also deliberate on the mechanisms responsible,the consequences for the refinement of PARP inhibitor use in the clinic,and future possibilities to circumvent drug resistance in DNA-repair deficient cancers.

关键词： Double strand break repair histone methylation PARP inhibitor resistance SETD1A BOD1L H3K4

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Plant species with extremely small populations(PSESP) in China:A seed and spore biology perspective

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Plant Diversity 2016年第5期38卷 209-220页

作者： ellie Merrett Wade Jayanthi Nadarajan Xiangyun Yang Daniel Ballesteros Weibang Sun Hugh W.Pritchard Royal Botanic Gardens KewWellcome Trust Millennium Building The Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of Sciences Kunming Botanical Garden Kunming Institute of BotanyChinese Academy of Sciences

Approximately one fifth of the world's plants are at risk of *** these,a significant number exist as populations of few individuals,with limited distribution ranges and under enormous pressure due to habitat *** China,these most-at-risk species are described as 'plant species with extremely small populations'(PSESP).Implementing conservation action for such listed species is *** seeds is one of the main means of ex situ conservation for flowering *** storage could provide a simple and economical method for fern ex situ *** and spore germination in nature is a critical step in species regeneration and thus in situ *** what is known about the seed and spore biology(storage and germination) of at-risk species? We have used China's PSESP(the first group listing) as a case study to understand the gaps in knowledge on propagule biology of threatened plant *** found that whilst germination information is available for 28 species(23%of PSESP),storage characteristics are only known for 8%of PSESP(10 species).Moreover,we estimate that 60%of the listed species may require cryopreservation for long-term *** conclude that comparative biology studies are urgently needed on the world's most threatened taxa so that conservation action can progress beyond species listing.

关键词： Threatened species Orchids Storage characteristics Cryopreservation ex situ conservation

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Order from Chaos: Self-Assembly of Nanoprism from a Mixture of Tetratopic Terpyridine-Porphyrin Conformers

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Chinese Journal of Chemistry 2019年第11期37卷 1167-1173页

作者： Alexander Filosa Heng Wang Wei-Jian Li Wenjing Zhang ellie Ngo Jonathan EPiccolo Hai-Bo Yang Xiaopeng Li Department of Chemistry University of South Florida4202 Fowler AvenueTampaFlorida 33620United States Shanghai Key Laboratory of Green Chemistry and Chemical Processes School of Chemistry and Molecular EngineeringEast China Normal University3663 N.Zhongshan RoadShanghai 200062China College of Chemistry and Molecular Engineering Zhengzhou UniversityZhengzhouHenan 450001China

Background and Originality Content Porphyrins are a vibrant class of organic dyes found widely in nature,ranging from the well-studied chlorophyll and heme found in the cells of plants and red blooded animals to the l... 详细信息

关键词： Porphyrin Chaos porphyrin

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Does the Type of Dive Mask Matter to a Shark?

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Open Journal of Animal Sciences 2020年第3期10卷 618-626页

作者： Erich Ritter Raid Amin ellie Farquhar Department of Statistics and Mathematics University of West Florida Pensacola FL USA Shark Research Institute Princeton NJ USA PHS Science Research Pawling NY USA

Eye contact with a shark is a crucial element during an interaction with a diver. Different mask frames change the size of a diver’s available field of vision, and so make a person’s eyes unequally visible from different angles, particularly when comparing mirrored to regular glass. This study examined whether it matters to a shark if it can see a diver’s eyes when getting closer. The test-subjects changed masks in a random, timed routine, while the relative distance, the absolute distance between a shark and diver expressed in a fraction of the shark’s body length, between approaching shark and human was tallied. Sharks came significantly closer (p = 0.0139) when a diver’s eyes could not be detected, showing that they orient themselves and approach based on the human’s eyes. Given that human comprehension of sharks is rudimentary, every possible benefit, even a minimal one like choosing the most optimal mask, is recommended whenever approaching sharks are likely to be encountered.

关键词： Approach Eye Contact Interruption Mask Shark

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年度回顾:2023年八大建筑故事

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艺术与设计（理论版） 2024年第1期 6-9页

作者：埃莉·斯塔塔基迈克尔·韦伯(摄影) 塞尔吉奥·皮罗内(摄影) 不详

从广受好评的2023年威尼斯建筑双年展的启动,到一系列文化空间和私人住宅的开放,让我们一同回顾2023年有关可持续发展、社区、创新和新兴人才的建筑故事。

关键词：私人住宅威尼斯建筑双年展可持续发展故事社区

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JavaScript by example

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1000年

作者： Quigley ellie.

来源：畅想之星图书光盘版（南... 评论

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