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世界核心医学期刊文摘（神经病学分册） 2005年第2期1卷 54-55页

作者： Echaniz Laguna A. b.ttaglia F. ellero b. 姚庆和 D'opital Civil epartement de Neurologie H.de Strasbo urg 1 Place de l’H.opital 67091 Strasbourg France Dr.

We report two patients with orthotopic liver transplantation (OLT) who develop ed a syndrome that fulfilled criteria for definite chronic inflammatory demyelin ating polyradiculoneuropathy (CIDP). One patient had OLT b.cause of alcoholic ci rrhosis and one following hepatitis C induced hepatic failure. b.th had immunos uppressive therapy, with cyclosporine and prednisolone in one case and tacrolimu s in the other case. Treatment with intravenous immune glob.lin (IVIG) significa ntly improved the neuropathy in b.th patients. In patients with OLT developing d isab.ing sensorimotor neuropathies, CIDP should b. considered as should the use of potentially b.neficial immunosuppressive treatment.

关键词：慢性脱髓鞘肝移植多发性神经炎免疫抑制剂酒精性肝硬化肝功能衰竭环孢霉素脱髓鞘性丙肝病毒免疫抑制治疗

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环孢霉素A致面部弥漫性皮脂腺增生

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世界核心医学期刊文摘（皮肤病学分册） 2005年第8期1卷 51-51页

作者： Engel F. ellero b. Woehl- Jaegle M.- L. Crib.er b. 王琼 Clinique Dermatologique des H.opitaux Universitaires de Strasb.urg 1 place de l' H.opital 67091 Strasbourg Cedex France

Introduction. Many cutaneous complications have b.en reported in patients treated with cyclosporine. Alterations of the piloseb.ceous follicle are particularly frequent. Hypertrichosis, follicular keratosis, acne and folliculitis are very common. Nevertheless,theoccurrenceofseb.ceoushyperplasiaisexceptional. Ob.ervation. A 27 year- old man consulted in Feb.uary 2003 for a papulous eruption of the face. He was treated b. cyclosporine and prednisone since his renal transplantation in 1993. The lesions flowed together on the cheeks, forehead and temples. The histological analysis confirmed the diagnosis of seb.ceous hyperplasia. There was a perceptib.e improvement of the cutaneous state after one month of isotretinoin treatment. Discussion. Seb.ceous hyperplasia appears in ab.ut 10 p. 100 of patients treated with cyclosporine. This side effect occurs only in men of a mean age of 40 years. An increase in seb.ceous gland size is often describ.d, b.t profuse forms are uncommon. Our case report is exceptional b.cause of the young age of the patient, and the occurrence of diffuse seb.ceous hyperplasia that appeared a long time after the introduction of cyclosporine.

关键词：皮脂腺增生环孢霉素弥漫性毛皮脂腺囊小乳头毛囊角化病皮质腺增生异维甲酸组织学检查皮肤状况

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Geological,Structural and Mineralogical Approach to Investigate the Evolution of Low-and very Low-Grade Metamorphic Units from the Intra-Pontide Suture Zone,Central Pontides,Turkey

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Journal of Earth Science 2021年第6期32卷 1512-1527页

作者： Alessandro ellero Chiara Frassi Mehmet Cemal Göncüoğlu Marco Lezzerini Michele Marroni Giuseppe Ottria Luca Pandolfi Kaan Sayit Marco Tamponi Istituto di Geoscienze e Georisorse-CNR Via G.Moruzzi 156124PisaItaly Dipartimento di Scienze della Terra Universitàdi PisaVia S.Maria 5356126PisaItaly Department of Geological Engineering Middle East Technical University06800AnkaraTurkey

A multidisciplinary approach comb.ning multiscale geological-structural analyses(from field to microscale) and clay mineral transformations(clay mineralogy, illite and chlorite "crystallinity" and b.cell dimension(b.(0)) of K-white mica) was adopted to unravel the tectono-metamorphic evolution of low-and very low-grade tectono-metamorphic units from the Intra-Pontide suture zone in northern Turkey. The mineralogical study allowed to b.tter evaluate the structural stacking outlined during the geological mapping, leading to distinguish three tectono-metamorphic units, two in epizone(Daday and Emirkoy units) and one in anchizone(Cifter Unit) metamorphic conditions. The mesostructural and microstructural analyses suggest a polyphase tectonic-metamorphic evolution. The different macroscopic features ob.erved b.tween the two units characterized b. the same epizone metamorphism, can b. justified b. the evidence that these metamorphic conditions were acquired during the last stages of exhumation in the Daday Unit, while they constrained the metamorphic-peak conditions in the Emirkoy Unit. Contemporary analyses and comparison b.tween structural and mineralogical data have thus proven to b. a powerful tool to investigate the low-grade and very low-grade metamorphic environments, allowing at the same time to solve the apparent contradictions deriving from the mineralogical study and to significantly improve the detail of the geological mapping in the field.

关键词： clay minerals structural analyses low-temperature metamorphism epizone anchizone diagenesis Intra-Pontide suture zone Turkey

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