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作者： ellen M.Cahill Kevin Chua sai Krishnaraya Doppalapudi saum Ghodoussipour Rutgers Robert Wood Johnson Medical school New BrunswickNJUSA section of Urologic Oncology Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNJ 08903-2681USA

Nonmuscle invasive bladder cancer is associated with a high risk of recurrence as well as progression to muscle-invasive ***,adequate visualization and identification of malignant lesions as well as complete resection are *** white-light cystoscopy is limited in its ability to detect bladder cancer,specifically carcinoma in ***-light cystoscopy makes use of the intravesical instillation of a heme precursor to differentiate areas of malignancy from normal tissue.A narrative review of the literature on the use of blue-light cystoscopy in bladder cancer was ***-light cystoscopy has been shown in several randomized clinical trials to increase detection of Ta,T1,and carcinoma in situ,as well as reduce risk of recurrence at 12 months as compared with traditional white-light *** into the effects of blue-light cystoscopy on risk of disease progression has produced mixed results,in part due to changing definitions of ***,more recent research suggests a correlation with decreased risk of *** the use of blue-light was initially limited to rigid cystoscopy in the operating room,results from a recent randomized clinical trial showing enhanced detection of recurrent disease using blue-light in-office surveillance flexible cystoscopy have led to expanded Food and Drug Administration ***,blue-light cystoscopy offers promise as an enhancement to white-light cystoscopy for the detection of nonmuscle invasive bladder cancer and may yield additional benefits in reducing disease recurrence and *** prospective research is needed to evaluate the true benefit of blue-light cystoscopy in terms of disease progression as well as the cost-effectiveness of this technique.

关键词： Nonmuscle invasive bladder cancer Blue-light cystoscopy White-light cystoscopy

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